Centre for Misfolding Diseases

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  • Currently displaying 1121 - 1140 of 2508 publications
Author(s)
Publication title
Journal Name
Publication year
Sequential Release of Proteins from Structured Multishell Microcapsules
U Shimanovich, TCT Michaels, E De Genst, D Matak-Vinkovic, CM Dobson, TPJ Knowles
Biomacromolecules
(2017)
18
(doi: 10.1021/acs.biomac.7b00351)
Paratope Prediction using Convolutional and Recurrent Neural Networks
E Liberis, P Veličković, P Sormanni, M Vendruscolo, P Liò
(2017)
(doi: 10.1101/185488)
Nickel-Catalyzed Azide-Alkyne Cycloaddition To Access 1,5-Disubstituted 1,2,3-Triazoles in Air and Water
WG Kim, ME Kang, JB Lee, MH Jeon, S Lee, J Lee, B Choi, PMSD Cal, S Kang, J-M Kee, GJL Bernardes, J-U Rohde, W Choe, SY Hong
J Am Chem Soc
(2017)
139
(doi: 10.1021/jacs.7b06338)
Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide.
GT Heller, FA Aprile, M Bonomi, C Camilloni, A De Simone, M Vendruscolo
Journal of molecular biology
(2017)
429
(doi: 10.1016/j.jmb.2017.07.016)
Kinetics of protein aggregation
T Knowles
FEBS JOURNAL
(2017)
284
Methods of probing the interactions between small molecules and disordered proteins
GT Heller, FA Aprile, M Vendruscolo
Cell Mol Life Sci
(2017)
74
(doi: 10.1007/s00018-017-2563-4)
Scaling behaviour and rate-determining steps in filamentous self-assembly.
G Meisl, L Rajah, SAI Cohen, M Pfammatter, A Šarić, E Hellstrand, AK Buell, A Aguzzi, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
Chemical Science
(2017)
8
(doi: 10.1039/c7sc01965c)
The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation.
F aprile, E Källstig, G Limorenko, Vendruscolo, D Ron, C hansen
Scientific Reports
(2017)
7
(doi: 10.1038/s41598-017-08324-z)
Rapid and accurate in silico solubility screening of a monoclonal antibody library.
P Sormanni, L Amery, S Ekizoglou, M Vendruscolo, B Popovic
Scientific Reports
(2017)
7
(doi: 10.1038/s41598-017-07800-w)
Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates
S Chia, P Flagmeier, J Habchi, V Lattanzi, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2017)
114
(doi: 10.1073/pnas.1700239114)
Silk micrococoons for protein stabilisation and molecular encapsulation.
U Shimanovich, FS Ruggeri, E De Genst, J Adamcik, TP Barros, D Porter, T Müller, R Mezzenga, CM Dobson, F Vollrath, C Holland, TPJ Knowles
Nature Communications
(2017)
8
(doi: 10.1038/ncomms15902)
The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis
MA Hanspal, CM Dobson, JJ Yerbury, JR Kumita
Biochimica Et Biophysica Acta Molecular Basis of Disease
(2017)
1863
(doi: 10.1016/j.bbadis.2017.07.007)
The contribution of biophysical and structural studies of protein self-assembly to the design of therapeutic strategies for amyloid diseases.
N Cremades, CM Dobson
Neurobiology of disease
(2017)
109
(doi: 10.1016/j.nbd.2017.07.009)
Protein homeostasis of a metastable subproteome associated with Alzheimer's disease
R Kundra, P Ciryam, RI Morimoto, CM Dobson, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2017)
114
(doi: 10.1073/pnas.1618417114)
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species
D Klenerman, M Iljina, L Hong, MH Horrocks, MH Ludtmann, ML Choi, CD Hughes, FS Ruggeri, T Guilliams, AK Buell, J-E Lee, S Gandhi, SF Lee, CE Bryant, M Vendruscolo, TPJ Knowles, CM Dobson, E De Genst, D Klenerman
BMC biology
(2017)
15
(doi: 10.1186/s12915-017-0390-6)
MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis
GL Isom, NJ Davies, Z-S Chong, JA Bryant, M Jamshad, M Sharif, AF Cunningham, TJ Knowles, S-S Chng, JA Cole, IR Henderson
(2017)
(doi: 10.1101/159053)
Structural characterisation of the early events in the nucleation-condensation mechanism of folding
P Kukic, Y Pustovalova, C Camilloni, S Gianni, DM Korzhnev, M Vendruscolo
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Single amyloid aggregates chemical and structural analysis by infrared nanospectroscopy
FS Ruggeri, J Habchi, C Sean, M Vendruscolo, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils
M Tornquist, R Cukalevski, U Weininger, G Meisl, TPJ Knowles, T Leiding, M Akke, S Linse
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Ultrasensitive measurement of Ca2+ influx into lipid vesicles induced by protein aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TP Knowles, S Gandhi, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Yusuf Hamied Department of Chemistry
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