Centre for Misfolding Diseases

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  • Currently displaying 1121 - 1140 of 2455 publications
Author(s)
Publication title
Journal Name
Publication year
Towards a structural biology of the hydrophobic effect in protein folding
C Camilloni, D Bonetti, A Morrone, R Giri, CM Dobson, M Brunori, S Gianni, M Vendruscolo
Scientific reports
(2016)
6
(doi: 10.1038/srep28285)
The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.
V Crippa, ME Cicardi, N Ramesh, SJ Seguin, M Ganassi, I Bigi, C Diacci, E Zelotti, M Baratashvili, JM Gregory, CM Dobson, C Cereda, UB Pandey, A Poletti, S Carra
Hum Mol Genet
(2016)
25
(doi: 10.1093/hmg/ddw232)
Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform
TO Mason, TCT Michaels, A Levin, E Gazit, CM Dobson, AK Buell, TPJ Knowles
J Am Chem Soc
(2016)
138
(doi: 10.1021/jacs.6b04136)
Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies.
R Cascella, C Capitini, G Fani, CM Dobson, C Cecchi, F Chiti
J Biol Chem
(2016)
291
(doi: 10.1074/jbc.M116.737726)
Correction: Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation.
H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois
Chem Sci
(2016)
7
(doi: 10.1039/c6sc90045c)
Unveiling (-)-EnglerinA as a Modulator of L-Type Calcium Channels
T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes
Angew Chem Int Ed Engl
(2016)
55
(doi: 10.1002/anie.201604336)
Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms.
M Iljina, GA Garcia, AJ Dear, J Flint, P Narayan, TCT Michaels, CM Dobson, D Frenkel, TPJ Knowles, D Klenerman
Scientific Reports
(2016)
6
(doi: 10.1038/srep28658)
Quantifying Measurement Fluctuations from Stochastic Surface Processes on Sensors with Heterogeneous Sensitivity
J Charmet, TCT Michaels, R Daly, A Prasad, P Thiruvenkathanathan, RS Langley, TPJ Knowles, AA Seshia
Physical Review Applied
(2016)
5
(doi: 10.1103/physrevapplied.5.064016)
Fluctuations in the Kinetics of Linear Protein Self-Assembly
TCT Michaels, AJ Dear, JB Kirkegaard, KL Saar, DA Weitz, TPJ Knowles
Phys Rev Lett
(2016)
116
(doi: 10.1103/physrevlett.116.258103)
Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation.
H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois
Chemical science
(2016)
7
(doi: 10.1039/c6sc01520d)
Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
C Galvagnion, JWP Brown, MM Ouberai, P Flagmeier, M Vendruscolo, AK Buell, E Sparr, CM Dobson
Proceedings of the National Academy of Sciences of the United States of America
(2016)
113
(doi: 10.1073/pnas.1601899113)
Structure of a low-population binding intermediate in protein-RNA recognition.
AN Borkar, MF Bardaro, C Camilloni, FA Aprile, G Varani, M Vendruscolo
Proc Natl Acad Sci U S A
(2016)
113
(doi: 10.1073/pnas.1521349113)
Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity
G Fusco, A De Simone, P Arosio, M Vendruscolo, G Veglia, CM Dobson
Sci Rep
(2016)
6
(doi: 10.1038/srep27125)
Particle-Based Monte-Carlo Simulations of Steady-State Mass Transport at Intermediate Peclet Numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
International Journal of Nonlinear Sciences and Numerical Simulation
(2016)
17
(doi: 10.1515/ijnsns-2015-0056)
Structural Effects of Two Camelid Nanobodies Directed to Distinct C-Terminal Epitopes on α-Synuclein.
F El-Turk, FN Newby, E De Genst, T Guilliams, T Sprules, A Mittermaier, CM Dobson, M Vendruscolo
Biochemistry
(2016)
55
(doi: 10.1021/acs.biochem.6b00149)
Ca2+ is a key factor in α-synuclein-induced neurotoxicity.
PR Angelova, MHR Ludtmann, MH Horrocks, A Negoda, N Cremades, D Klenerman, CM Dobson, NW Wood, EV Pavlov, S Gandhi, AY Abramov
Development (Cambridge, England)
(2016)
143
(doi: 10.1242/dev.139345)
Amyloid fibrils as building blocks for natural and artificial functional materials
TPJ Knowles, R Mezzenga
Advanced Materials
(2016)
28
(doi: 10.1002/adma.201505961)
A Microfluidic Platform for Real-Time Detection and Quantification of Protein-Ligand Interactions
TW Herling, DJ O'Connell, MC Bauer, J Persson, U Weininger, TPJ Knowles, S Linse
Biophysical journal
(2016)
110
(doi: 10.1016/j.bpj.2016.03.038)
Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability
C Camilloni, BM Sala, P Sormanni, R Porcari, A Corazza, M De Rosa, S Zanini, A Barbiroli, G Esposito, M Bolognesi, V Bellotti, M Vendruscolo, S Ricagno
Scientific reports
(2016)
6
(doi: 10.1038/srep25559)
Self-assembly of MPG1, a hydrophobin protein from the rice blast fungus that forms functional amyloid coatings, occurs by a surface-driven mechanism.
CLL Pham, A Rey, V Lo, M Soulès, Q Ren, G Meisl, TPJ Knowles, AH Kwan, M Sunde
Scientific reports
(2016)
6
(doi: 10.1038/srep25288)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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