Centre for Misfolding Diseases

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  • Currently displaying 1161 - 1180 of 2474 publications
Author(s)
Publication title
Journal Name
Publication year
Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning.
PK Challa, T Kartanas, J Charmet, TPJ Knowles
Biomicrofluidics
(2017)
11
(doi: 10.1063/1.4976690)
On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products
KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, X Yang, S Linse, TPJ Knowles
Lab on a Chip
(2017)
18
(doi: 10.1039/c7lc00797c)
Oxidative activation of C-S bonds with an electropositive nitrogen promoter enables orthogonal glycosylation of alkyl over phenyl thioglycosides
A Kitowski, E Jiménez-Moreno, M Salvadó, J Mestre, S Castillón, G Jiménez-Osés, O Boutureira, GJL Bernardes
Organic letters
(2017)
19
(doi: 10.1021/acs.orglett.7b02886)
Norbornene probes for the study of cysteine oxidation
LJ Alcock, KD Farrell, MT Akol, GH Jones, MM Tierney, HB Kramer, TL Pukala, GJL Bernardes, MV Perkins, JM Chalker
Tetrahedron
(2017)
74
(doi: 10.1016/j.tet.2017.11.011)
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease
J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences
(2016)
114
(doi: 10.1073/pnas.1615613114)
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping.
MN Bongiovanni, J Godet, MH Horrocks, L Tosatto, AR Carr, DC Wirthensohn, RT Ranasinghe, JV Fritz, CM Dobson, D Klenerman, SF Lee
Nature Communications
(2016)
7
(doi: 10.1038/ncomms13544)
Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
J Chem Phys
(2016)
145
(doi: 10.1063/1.4965040)
The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme
M Ahn, CL Hagan, A Bernardo-Gancedo, E De Genst, FN Newby, J Christodoulou, A Dhulesia, M Dumoulin, CV Robinson, CM Dobson, JR Kumita
Biophysical Journal
(2016)
111
(doi: 10.1016/j.bpj.2016.10.028)
Micro- and nanoscale hierarchical structure of core–shell protein microgels
LR Volpatti, U Shimanovich, FS Ruggeri, S Bolisetty, T Müller, TO Mason, TCT Michaels, R Mezzenga, G Dietler, TPJ Knowles
J Mater Chem B
(2016)
4
(doi: 10.1039/c6tb02683d)
Trends in therapeutic drug conjugates for bacterial diseases: a patent review
PMSD Cal, MJ Matos, GJL Bernardes
Expert opinion on therapeutic patents
(2016)
27
(doi: 10.1080/13543776.2017.1259411)
The missing link
T Rodrigues, GJL Bernardes
Nature chemistry
(2016)
8
(doi: 10.1038/nchem.2685)
A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez-Osés, GJL Bernardes
Angew Chem Int Ed Engl
(2016)
55
(doi: 10.1002/anie.201608438)
A Minimal, Unstrained S‐Allyl Handle for Pre‐Targeting Diels–Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez‐Osés, GJL Bernardes
Angewandte Chemie
(2016)
128
(doi: 10.1002/ange.201608438)
Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ
DC Butler, SN Joshi, ED Genst, AS Baghel, CM Dobson, A Messer
PLoS One
(2016)
11
(doi: 10.1371/journal.pone.0165964)
Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents.
T Rodrigues, F Sieglitz, GJL Bernardes
Chem Soc Rev
(2016)
45
(doi: 10.1039/c5cs00916b)
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, WL Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, ML Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis
Science (New York, N.Y.)
(2016)
354
Dynamics of heteromolecular filament formation.
AJ Dear, TCT Michaels, TPJ Knowles
J Chem Phys
(2016)
145
(doi: 10.1063/1.4966571)
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces
JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, M Vendruscolo, TPJ Knowles, CM Dobson, C Galvagnion
Sci Rep
(2016)
6
(doi: 10.1038/srep36010)
Structural Characteristics of α-Synuclein Oligomers
N Cremades, SW Chen, CM Dobson
International Review of Cytology
(2016)
329
(doi: 10.1016/bs.ircmb.2016.08.010)
Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
B Bernardim, PMSD Cal, MJ Matos, BL Oliveira, N Martínez-Sáez, IS Albuquerque, E Perkins, F Corzana, ACB Burtoloso, G Jiménez-Osés, GJL Bernardes
Nature communications
(2016)
7
(doi: 10.1038/ncomms13128)
Yusuf Hamied Department of Chemistry
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