Centre for Misfolding Diseases

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  • Currently displaying 1161 - 1180 of 2489 publications
Author(s)
Publication title
Journal Name
Publication year
Effects of Amyloid-Beta Expression on Neuronal Signalling Pathways in a Novel C. elegans Model of Alzheimer's Disease
T Sinnige, P Ciryam, CM Dobson, M de Bono, M Vendruscolo
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.878)
Attenuating the Toxicity of Amyloid-Beta Aggregation with Specific Species
R Limbocker, B Mannini, M Perni, S Chia, G Heller, FS Ruggeri, J Habchi, G Meisl, PK Challa, M Zasloff, TPJ Knowles, M Vendruscolo, CM Dobson
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.2673)
Characterization of Protein Kinase a Free Energy Landscape by NMR-Restrained Metadynamics
Y Wang, C Camilloni, J Kim, M Vendruscolo, J Gao, G Veglia
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.310)
Simultaneous NMR characterisation of multiple minima in the free energy landscape of an RNA UUCG tetraloop
AN Borkar, P Vallurupalli, C Camilloni, LE Kay, M Vendruscolo
Physical chemistry chemical physics : PCCP
(2017)
19
(doi: 10.1039/c6cp08313g)
Networks of Dynamic Allostery Regulate Enzyme Function.
MJ Holliday, C Camilloni, GS Armstrong, M Vendruscolo, EZ Eisenmesser
Structure
(2017)
25
(doi: 10.1016/j.str.2016.12.003)
Site-selective installation of BASHY fluorescent dyes to Annexin V for targeted detection of apoptotic cells
PMSD Cal, F Sieglitz, FMF Santos, C Parente Carvalho, A Guerreiro, JB Bertoldo, U Pischel, PMP Gois, GJL Bernardes
Chemical Communications
(2017)
53
(doi: 10.1039/c6cc08671c)
Principles of protein structural ensemble determination.
M Bonomi, GT Heller, C Camilloni, M Vendruscolo
Curr Opin Struct Biol
(2017)
42
(doi: 10.1016/j.sbi.2016.12.004)
Kinetics of spontaneous filament nucleation via oligomers: insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
(2017)
(doi: 10.48550/arxiv.1610.02320)
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells
E Jiménez-Moreno, Z Guo, BL Oliveira, IS Albuquerque, A Kitowski, A Guerreiro, O Boutureira, T Rodrigues, G Jiménez-Osés, GJL Bernardes
Angewandte Chemie International Edition
(2017)
56
(doi: 10.1002/anie.201609607)
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells
E Jiménez‐Moreno, Z Guo, BL Oliveira, IS Albuquerque, A Kitowski, A Guerreiro, O Boutureira, T Rodrigues, G Jiménez‐Osés, GJL Bernardes
Angewandte Chemie
(2017)
129
(doi: 10.1002/ange.201609607)
Oxidative Activation of C-S Bonds with an Electropositive Nitrogen Promoter Enables Orthogonal Glycosylation of Alkyl over Phenyl Thioglycosides
A Kitowski, E Jiménez-Moreno, M Salvadó, J Mestre, S Castillón, G Jiménez-Osés, O Boutureira, GJL Bernardes
Organic Letters
(2017)
19
(doi: 10.1021/acs.orglett.7b02886)
On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products.
KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, X Yang, S Linse, TPJ Knowles
Lab Chip
(2017)
18
(doi: 10.1039/c7lc00797c)
In situ characterization of advanced glycation end products (AGEs) in collagen and model extracellular matrix by solid state NMR
R Li, R Rajan, WCV Wong, DG Reid, MJ Duer, VJ Somovilla, N Martinez-Saez, GJL Bernardes, R Hayward, CM Shanahan
Chemical communications (Cambridge, England)
(2017)
53
(doi: 10.1039/c7cc06624d)
Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning.
PK Challa, T Kartanas, J Charmet, TPJ Knowles
Biomicrofluidics
(2017)
11
(doi: 10.1063/1.4976690)
Secondary nucleation of monomers on fibril surface dominates $\alpha$-synuclein aggregation and provides autocatalytic amyloid amplification
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
Q Rev Biophys
(2017)
50
(doi: 10.1017/S0033583516000172)
Norbornene probes for the study of cysteine oxidation
LJ Alcock, KD Farrell, MT Akol, GH Jones, MM Tierney, HB Kramer, TL Pukala, GJL Bernardes, MV Perkins, JM Chalker
Tetrahedron
(2017)
74
(doi: 10.1016/j.tet.2017.11.011)
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease.
J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2016)
114
(doi: 10.1073/pnas.1615613114)
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping
MN Bongiovanni, J Godet, MH Horrocks, L Tosatto, AR Carr, DC Wirthensohn, RT Ranasinghe, JV Fritz, CM Dobson, D Klenerman, SF Lee
Nature Communications
(2016)
7
(doi: 10.1038/ncomms13544)
Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation.
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
The Journal of chemical physics
(2016)
145
(doi: 10.1063/1.4965040)
The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme
M Ahn, CL Hagan, A Bernardo-Gancedo, E De Genst, FN Newby, J Christodoulou, A Dhulesia, M Dumoulin, CV Robinson, CM Dobson, JR Kumita
Biophys J
(2016)
111
(doi: 10.1016/j.bpj.2016.10.028)
Yusuf Hamied Department of Chemistry
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