Centre for Misfolding Diseases

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  • Currently displaying 1161 - 1180 of 2508 publications
Author(s)
Publication title
Journal Name
Publication year
Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants.
G Meisl, X Yang, CM Dobson, S Linse, TPJ Knowles
Chemical Science
(2017)
8
(doi: 10.1039/c7sc00215g)
The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage
J Kitevski-LeBlanc, A Fradet-Turcotte, P Kukic, MD Wilson, G Portella, T Yuwen, S Panier, S Duan, MD Canny, H van Ingen, CH Arrowsmith, JL Rubinstein, M Vendruscolo, D Durocher, LE Kay
Elife
(2017)
6
(doi: 10.7554/eLife.23872)
Emergence and evolution of an interaction between intrinsically disordered proteins.
G Hultqvist, E Åberg, C Camilloni, GN Sundell, E Andersson, J Dogan, CN Chi, M Vendruscolo, P Jemth
eLife
(2017)
6
(doi: 10.7554/eLife.16059)
Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS
P Ciryam, IA Lambert-Smith, DM Bean, R Freer, F Cid, GG Tartaglia, DN Saunders, MR Wilson, SG Oliver, RI Morimoto, CM Dobson, M Vendruscolo, G Favrin, JJ Yerbury
Proceedings of the National Academy of Sciences of USA
(2017)
114
(doi: 10.1073/pnas.1613854114)
Intra-chain organisation of hydrophobic residues controls inter-chain aggregation rates of amphiphilic polymers
P Varilly, AP Willard, JB Kirkegaard, TPJ Knowles, D Chandler
The Journal of chemical physics
(2017)
146
(doi: 10.1063/1.4977932)
A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages
MMA Pereira, I Mahú, E Seixas, N Martinéz-Sánchez, N Kubasova, RM Pirzgalska, P Cohen, MO Dietrich, M López, GJL Bernardes, AI Domingos
Nature Communications
(2017)
8
(doi: 10.1038/ncomms14967)
MOAG-4 promotes the aggregation of α-synuclein by competing with self-protective electrostatic interactions
Y Yoshimura, MA Holmberg, P Kukic, CB Andersen, A Mata-Cabana, SF Falsone, M Vendruscolo, EAA Nollen, FAA Mulder
Journal of Biological Chemistry
(2017)
292
(doi: 10.1074/jbc.M116.764886)
Simultaneous quantification of protein order and disorder.
P Sormanni, D Piovesan, GT Heller, M Bonomi, P Kukic, C Camilloni, M Fuxreiter, Z Dosztanyi, RV Pappu, MM Babu, S Longhi, P Tompa, AK Dunker, VN Uversky, SCE Tosatto, M Vendruscolo
Nat Chem Biol
(2017)
13
(doi: 10.1038/nchembio.2331)
Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation
O Sin, T de Jong, A Mata-Cabana, M Kudron, MA Zaini, FA Aprile, RI Seinstra, E Stroo, RW Prins, CN Martineau, HH Wang, W Hogewerf, A Steinhof, EE Wanker, M Vendruscolo, CF Calkhoven, V Reinke, V Guryev, EAA Nollen
Mol Cell
(2017)
65
(doi: 10.1016/j.molcel.2017.02.022)
Exciton Coupling of Phenylalanine Reveals Conformational Changes of Cationic Peptides
C Bortolini, L Liu, SV Hoffmann, NC Jones, TPJ Knowles, M Dong
ChemistrySelect
(2017)
2
(doi: 10.1002/slct.201601916)
Physical principles of filamentous protein self-assembly kinetics
TCT Michaels, LX Liu, G Meisl, TPJ Knowles
Journal of Physics: Condensed Matter
(2017)
29
(doi: 10.1088/1361-648X/aa5f10)
Inhibition of α‑Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α‑Synuclein Species
FA Aprile, P Arosio, G Fusco, SW Chen, JR Kumita, A Dhulesia, P Tortora, TPJ Knowles, M Vendruscolo, CM Dobson, N Cremades
Biochemistry
(2017)
56
(doi: 10.1021/acs.biochem.6b01178)
Correction for Perni et al., A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Mueller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
Proceedings of the National Academy of Sciences of the United States of America
(2017)
114
(doi: 10.1073/pnas.1701964114)
Bayesian weighing of electron cryo-microscopy data for integrative structural modeling
M Bonomi, S Hanot, CH Greenberg, A Sali, M Nilges, M Vendruscolo, R Pellarin
(2017)
(doi: 10.1101/113951)
Acceleration of α-synuclein aggregation.
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
Amyloid
(2017)
24
(doi: 10.1080/13506129.2017.1292904)
Widespread Proteome Remodeling and Aggregation in Aging C. elegans
DM Walther, P Kasturi, M Zheng, S Pinkert, G Vecchi, P Ciryam, RI Morimoto, CM Dobson, M Vendruscolo, M Mann, FU Hartl
Cell
(2017)
168
(doi: 10.1016/j.cell.2016.12.041)
Plagues and history: From the black death to alzheimer’s disease
C Dobson, M Dobson
(2017)
(doi: 10.1017/9781108147910.004)
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
Proc Natl Acad Sci U S A
(2017)
114
(doi: 10.1073/pnas.1610586114)
Structural Investigation of an Immunoglobulin Domain on the Ribosome using NMR Spectroscopy
AME Cassaignau, HMM Launay, CA Waudby, T Wlodarski, M-E Karyadi, AL Robertson, X Wang, C Camilloni, M Vendruscolo, CA Woolhead, L Cabrita, J Christodoulou
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.258)
Attenuating the Toxicity of Amyloid-Beta Aggregation with Specific Species
R Limbocker, B Mannini, M Perni, S Chia, G Heller, FS Ruggeri, J Habchi, G Meisl, PK Challa, M Zasloff, TPJ Knowles, M Vendruscolo, CM Dobson
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.2673)
Yusuf Hamied Department of Chemistry
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