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Currently displaying 1 - 20 of 2473 publications

In vitro liquid-liquid phase separation induced by respiratory syncytial virus proteins and RNA.

V Basse, T Agarwal, T Sneideris, C-A Richard, J Troussier, J-J Vasseur, F Debart, J-F Eléouët, E de Csillery, T Knowles, M Galloux

Science advances

(2026)

eaee2110

(doi: 10.1126/sciadv.aee2110)

Glutathione-Responsive Fragmentation of Heteronorbornadiene-Based Thiovinyl Sulfones in Glioma Cells.

M Carranza, AT Carmona, E Gil de Montes, Y Méndez, I Černauskienė, GJL Bernardes, AJ Moreno-Vargas

Bioconjug Chem

(2026)

acs.bioconjchem.5c00581

(doi: 10.1021/acs.bioconjchem.5c00581)

The role of N-terminal acetylation on biomolecular condensation

C G Oliveira, MTS Silva, E Kava, T Agarwal, G Cereghetti, E F Vicente, TPJ Knowles, AJ Costa-Filho, LFS Mendes

Commun Chem

(2026)

(doi: 10.1038/s42004-026-01975-y)

Spatially patterned, spectral single-molecule microscopy

JS Beckwith, B Cullinane, DF Heraghty, S Krokowski, CL Jones, S Yang, RC Gregory, RA Floto, AM Santos, SJ Davis, M Vendruscolo, D Klenerman, V Lindo, PK Sankaran, SF Lee

(2026)

(doi: 10.64898/2026.04.08.715690)

Microglia as transcriptional pacemakers of neuronal aging heterogeneity across individuals

CM Lim, M Vendruscolo

(2026)

(doi: 10.64898/2026.04.05.716624)

Rapid elongation drives the exceptionally fast aggregation of the most common localized human amyloid medin

V Roy Chowdhury, RI Horne, MP Cali, Z Toprakcioglu, S Linse, M Vendruscolo

Communications Chemistry

(2026)

(doi: 10.1038/s42004-026-01950-7)

Deep learning assessment of nativeness and pairing likelihood for antibody and nanobody design with AbNatiV2

A Ramon, N Frassetto, H Zhao, X Xu, M Greenig, S Onuoha, P Sormanni

Mabs

(2026)

2646361

(doi: 10.1080/19420862.2026.2646361)

Nucleation Kinetics Reveals a Distinct Biological Function Space of Biomolecular Condensates.

L-T Deck, SN Pacheco, H Ausserwöger, D Frenkel, NA Erkamp, TPJ Knowles

Advanced Science

(2026)

e22585

(doi: 10.1002/advs.202522585)

NPM1 Undergoes Salt-Dependent Reentrant Phase Separation Driven by IDR Conformational Plasticity and Electrostatic Crosstalk

Y Zhen, Y Tan, Y Tang, T Sneideris, H Ausserwöger, J Wen, TPJ Knowles, S Perrett, G Wei, S Wu

Small (Weinheim an der Bergstrasse, Germany)

(2026)

e14678

(doi: 10.1002/smll.202514678)

Discovery of first-in-class YTHDC1 small molecule inhibitors for the treatment of MYC-driven cancers

RC Centore, M Charles, M Arora, M Rebmann, MJ Rawling, J Cattin, X Yang, E Batchelor, M Watson, N Bharatham, A Howarth, S Qamar, L Andraghetti, A Seeber, MG Kharas, S Cohen, M Kulander, T Knowles, S Arora

Cancer Research

(2026)

7101

(doi: 10.1158/1538-7445.AM2026-7101)

Reversible peptide self-assembly enables sustained drug delivery with tuneable pharmacokinetics

TW Herling, J Wei, S Genapathy, C Rivera, M Persson, P Gennemark, D Workman, D Lundberg, E Bernard, H Bolt, MY Arteta, S Will, A Bak, D Hornigold, TPJ Knowles, ALG dos Santos

(2026)

(doi: 10.64898/2026.03.25.714189)

Systems-level organization of extracellular proteostasis.

CM Gomes, M Vendruscolo

Science

(2026)

391

1332

(doi: 10.1126/science.aed3712)

Formation of S- and Z-twist supramolecular micro-ropes by peptide stereoisomers

H Yuan, Z Yang, C Yuan, S Shankar, A Levin, T Lv, Z Wang, W Sun, J Sitton, P-A Cazade, Y Dan, Y Tang, L Adler-Abramovich, Y Cao, S Rencus-Lazar, D Thompson, D Kurouski, TPJ Knowles, LJW Shimon, G Wei, B Xue, R Yang, E Gazit

Nature communications

(2026)

(doi: 10.1038/s41467-026-71043-5)

Selective TRPV2 Antagonists Derived from the Natural Product Piperlongumine Inhibit Cancer Cell Migration and Metastasis

H Kiely-Collins, C Tang, MC Marques, L Butron, A Lamberti, N Bossons, F Offensperger, V Brennsteiner, B Sousa, L Carvalho, A Ferrer-Montiel, F Corzana, GE Winter, A Fernandez-Carvajal, GJL Bernardes

ACS chemical biology

(2026)

674

(doi: 10.1021/acschembio.5c00935)

Tau catalyzes amyloid-β aggregation and toxicity in a polymorph-dependent manner

M Mosconi, C Leonardi, Z Armour-Garb, B Rocutto, M Beeg, G Meisl, L Ortigosa-Pascual, L Broggini, M Salmona, S Ricagno, TPJ Knowles, L Diomede

Proceedings of the National Academy of Sciences

(2026)

123

e2532775123

(doi: 10.1073/pnas.2532775123)

OmniBind: Proteome-Wide Promiscuity Predictions for Early-Stage Drug Screening