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  • Currently displaying 1 - 20 of 3276 publications
Non‐natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity
A Guerreiro, I Compañón, FS Lazaris, C Labão-Almeida, P Oroz, M Ghirardello, MC Marques, F Corzana, GJL Bernardes
– Angewandte Chemie International Edition
(2024)
(doi: 10.1002/anie.202411009)
Single-molecule digital sizing of proteins in solution
G Krainer, RPB Jacquat, MM Schneider, TJ Welsh, J Fan, QAE Peter, EA Andrzejewska, G Šneiderienė, MA Czekalska, H Ausserwoeger, L Chai, WE Arter, KL Saar, TW Herling, TM Franzmann, V Kosmoliaptsis, S Alberti, FU Hartl, SF Lee, TPJ Knowles
– Nature Communications
(2024)
15,
7740
(doi: 10.1038/s41467-024-50825-9)
A human neuronal model of sporadic Alzheimer's disease induced by FBXO2 downregulation shows A β aggregation, tau hyperphosphorylation and functional network impairment
AG Díaz, A Possenti, GA Urrutia, Y Bian, S Kedia, D Boeken, CM Lim, D Licastro, B Mannini, D Klenerman, M Vendruscolo
(2024)
(doi: 10.1101/2024.09.01.610673)
TNF⍺-driven Aβ aggregation, synaptic dysfunction and hypermetabolism in human iPSC-derived cortical neurons
AG Díaz, E Belli, B Mannini, GA Urrutia, M Vendruscolo
(2024)
(doi: 10.1101/2024.08.30.610594)
Unraveling the Structure and Dynamics of Ac-PHF6-NH2 Tau Segment Oligomers
I Stroganova, Z Toprakcioglu, H Willenberg, TPJ Knowles, AM Rijs
– ACS Chem Neurosci
(2024)
(doi: 10.1021/acschemneuro.4c00404)
Surface effects on functional amyloid formation.
AJ Dear, G Meisl, CG Taylor, UC Palmiero, SN Stubbe, Q Liu, P Arosio, S Linse, TPJ Knowles, M Andreasen
– Nanoscale
(2024)
16,
16172
(doi: 10.1039/d4nr01496k)
Proximity-driven site-specific cyclization of phage-displayed peptides
L Brown, AV Vidal, AL Dias, T Rodrigues, A Sigurdardottir, T Journeaux, S O'Brien, TV Murray, P Ravn, M Papworth, GJL Bernardes
– Nature Communications
(2024)
15,
7308
(doi: 10.1038/s41467-024-51610-4)
Formation of Nanofibrillar Self-Healing Hydrogels Using Antimicrobial Peptides
EG Wiita, Z Toprakcioglu, AK Jayaram, TPJ Knowles
– ACS Applied Materials and Interfaces
(2024)
16,
46167
(doi: 10.1021/acsami.4c11542)
Small Molecule RNA Degraders.
J Bonet-Aleta, T Maehara, BA Craig, GJL Bernardes
– Angewandte Chemie (International ed. in English)
(2024)
e202412925
(doi: 10.1002/anie.202412925)
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates
NA Erkamp, M Farag, Y Qiu, D Qian, T Sneideris, T Wu, TJ Welsh, H Ausserwӧger, TJ Krug, DA Weitz, M Lew, TPJ Knowles, RV Pappu
(2024)
(doi: 10.1101/2024.08.19.608662)
Primary culture of high grade serous ovarian cancer cells, selection and derivation of three cell lines
JD Brenton, M Vias, CM Sauer, G Funingana, AM Piskorz, E Moore, C Chilamakuri, D Hall, T Goranova, E Van Oudenhove, HM Earl, I Goldlust
(2024)
(doi: 10.1101/2024.08.15.607946)
α-Synuclein oligomers form by secondary nucleation.
CK Xu, G Meisl, EA Andrzejewska, G Krainer, AJ Dear, M Castellana-Cruz, S Turi, IA Edu, G Vivacqua, RPB Jacquat, WE Arter, MG Spillantini, M Vendruscolo, S Linse, TPJ Knowles
– Nat Commun
(2024)
15,
7083
(doi: 10.1038/s41467-024-50692-4)
AlphaFold2-based prediction of the co-condensation propensity of proteins
S Zhang, CM Lim, M Occhetta, M Vendruscolo
– Proceedings of the National Academy of Sciences of the United States of America
(2024)
121,
e2315005121
(doi: 10.1073/pnas.2315005121)
A Fragment‐Based Competitive 19F LB‐NMR Platform For Hotspot‐Directed Ligand Profiling
WJ McCarthy, SE Thomas, T Olaleye, JA Boland, RA Floto, G Williams, TL Blundell, AG Coyne, C Abell
– Angewandte Chemie
(2024)
136,
e202406846
(doi: 10.1002/ange.202406846)
Gold (III)-Induced Amide Bond Cleavage In Vivo: A Dual Release Strategy via π-acid Mediated Allyl Substitution
VB Unnikrishnan, V Sabatino, F Amorim, MF Estrada, CD Navo, G Jimenez-Oses, R Fior, GJL Bernardes
– Journal of the American Chemical Society
(2024)
146,
23240
(doi: 10.1021/jacs.4c05582)
Dominance analysis to assess solute contributions to multicomponent phase equilibria.
D Qian, H Ausserwoger, T Sneideris, M Farag, RV Pappu, TPJ Knowles
– Proceedings of the National Academy of Sciences
(2024)
121,
e2407453121
(doi: 10.1073/pnas.2407453121)
Phase transitions in rolling of irregular cylinders and spheres
D Qian, Y Jung, L Mahadevan
(2024)
(link to publication)
Estimation of ligand binding free energy using multi-eGO.
B Stegani, E Scalone, F Bacic Toplek, T Lohr, S Gianni, M Vendruscolo, R Capelli, C Camilloni
(2024)
(doi: 10.26434/chemrxiv-2024-jcmgc)
On-Demand Thio-Succinimide Hydrolysis for the Assembly of Stable Protein-Protein Conjugates
AV Vasco, RJ Taylor, Y Méndez, GJL Bernardes
– J Am Chem Soc
(2024)
146,
20709
(doi: 10.1021/jacs.4c03721)
Protein Condensate Atlas from predictive models of heteromolecular condensate composition
KL Saar, RM Scrutton, K Bloznelyte, AS Morgunov, LL Good, AA Lee, SA Teichmann, TPJ Knowles
– Nature Communications
(2024)
15,
5418
(doi: 10.1038/s41467-024-48496-7)

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