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  • Currently displaying 1 - 20 of 3347 publications
Chemistry of “On‐Water” Reactions
AG Coyne
(2025)
11
(doi: 10.1002/9783527846849.ch2)
Prediction of protein biophysical traits from limited data: a case study on nanobody thermostability through NanoMelt.
A Ramon, M Ni, O Predeina, R Gaffey, P Kunz, S Onuoha, P Sormanni
– MAbs
(2025)
17,
2442750
(doi: 10.1080/19420862.2024.2442750)
Estimation of Ligand Binding Free Energy Using Multi-eGO
B Stegani, E Scalone, FB Toplek, T Löhr, S Gianni, M Vendruscolo, R Capelli, C Camilloni
– J Chem Inf Model
(2024)
(doi: 10.1021/acs.jcim.4c01545)
Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform
D Böken, Z Xia, JYL Lam, E Fertan, Y Wu, EA English, J Konc, F Layburn, GJL Bernardes, H Zetterberg, MR Cheetham, D Klenerman
– Analytical chemistry
(2024)
(doi: 10.1021/acs.analchem.4c04188)
In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds
N Watamura, MS Foiani, S Bez, M Bourdenx, A Santambrogio, C Frodsham, E Camporesi, G Brinkmalm, H Zetterberg, S Patel, N Kamano, M Takahashi, J Rueda-Carrasco, L Katsouri, S Fowler, E Turkes, S Hashimoto, H Sasaguri, T Saito, AS Islam, S Benner, T Endo, K Kobayashi, C Ishida, M Vendruscolo, M Yamada, KE Duff, TC Saido
– Nature Neuroscience
(2024)
1
(doi: 10.1038/s41593-024-01829-7)
Proteostasis Signatures in Human Diseases
CM Lim, M Vendruscolo
(2024)
(doi: 10.1101/2024.12.23.630032)
Tau accumulation patterns in PSP constrain mechanisms and quantify cell-to-cell and cell-autonomous aggregation rates
S-H Huang, A Quaegebeur, T Pansuwan, T Rittman, R Wang, TPJ Knowles, JB Rowe, D Klenerman, G Meisl
(2024)
(doi: 10.1101/2024.12.14.24318991)
Estimation of ligand binding free energy using multi-eGO.
B Stegani, E Scalone, F Bacic Toplek, T Lohr, S Gianni, M Vendruscolo, R Capelli, C Camilloni
(2024)
(doi: 10.26434/chemrxiv-2024-jcmgc-v2)
Detecting and Tracking β-Amyloid Oligomeric Forms and Dynamics In Vitro by a High-Sensitivity Fluorescent-Based Assay
Y Zhao, O Brener, E Andrzejewska, J Wei, C Reiß, O Tietz, TPJ Knowles, FI Aigbirhio
– ACS Chem Neurosci
(2024)
15,
4383
(doi: 10.1021/acschemneuro.4c00312)
Language Models for Molecular Dynamics
MH Murtada, ZF Brotzakis, M Vendruscolo
(2024)
(doi: 10.1101/2024.11.25.625337)
Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models.
JS Bedia, Y-W Huang, AD Gonzalez, VD Gonzalez, I-G Funingana, Z Rahil, A Mike, A Lowber, M Vias, A Ashworth, JD Brenton, WJ Fantl
– bioRxiv
(2024)
(doi: 10.1101/2024.11.21.624591)
Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen
T Knowles, Y Yao, N Erkamp, T Sneideris, X Yang, R Scrutton, M Schneider, C Fischer, E Schoenmakers, N Schoenmakers
(2024)
(doi: 10.21203/rs.3.rs-5139555/v1)
Assessment of fine-tuned large language models for real-world chemistry and material science applications.
J Van Herck, MV Gil, KM Jablonka, A Abrudan, AS Anker, M Asgari, B Blaiszik, A Buffo, L Choudhury, C Corminboeuf, H Daglar, AM Elahi, IT Foster, S Garcia, M Garvin, G Godin, LL Good, J Gu, N Xiao Hu, X Jin, T Junkers, S Keskin, TPJ Knowles, R Laplaza, M Lessona, S Majumdar, H Mashhadimoslem, RD McIntosh, SM Moosavi, B Mouriño, F Nerli, C Pevida, N Poudineh, M Rajabi-Kochi, KL Saar, F Hooriabad Saboor, M Sagharichiha, KJ Schmidt, J Shi, E Simone, D Svatunek, M Taddei, I Tetko, D Tolnai, S Vahdatifar, J Whitmer, DCF Wieland, R Willumeit-Römer, A Züttel, B Smit
– Chemical science
(2024)
16,
670
(doi: 10.1039/d4sc04401k)
The inhibitory action of the chaperone BRICHOS against the α-Synuclein secondary nucleation pathway.
D Ghosh, F Torres, MM Schneider, D Ashkinadze, H Kadavath, Y Fleischmann, S Mergenthal, P Güntert, G Krainer, EA Andrzejewska, L Lin, J Wei, E Klotzsch, T Knowles, R Riek
– Nat Commun
(2024)
15,
10038
(doi: 10.1038/s41467-024-54212-2)
A scale-invariant log-normal droplet size distribution below the critical concentration for protein phase separation.
T Amico, ST Dada, A Lazzari, M Brezinova, A Trovato, M Vendruscolo, M Fuxreiter, A Maritan
– Elife
(2024)
13,
RP94214
(doi: 10.7554/eLife.94214)
A scale-invariant log-normal droplet size distribution below the critical concentration for protein phase separation
T Amico, ST Dada, A Lazzari, M Brezinova, A Trovato, M Vendruscolo, M Fuxreiter, A Maritan
– eLife
(2024)
13,
(doi: 10.7554/elife.94214.3)
Site‐Specific Quadruple‐Functionalised Antibodies
T Journeaux, MB Geeson, TV Murray, MA Papworth, M Gothard, JG Kettle, AV Vasco, GJL Bernardes
– Angewandte Chemie International Edition
(2024)
e202417620
(doi: 10.1002/anie.202417620)
Site‐Specific Quadruple‐Functionalised Antibodies
T Journeaux, MB Geeson, TV Murray, MA Papworth, M Gothard, JG Kettle, AV Vasco, GJL Bernardes
– Angewandte Chemie
(2024)
e202417620
(doi: 10.1002/ange.202417620)
Dynamically arrested condensate fusion creates complex structures with varying material properties
N Erkamp, I Sanchez-Burgos, A Zhou, T Krug, S Qamar, T Sneideris, E Zhang, K Nakajima, A Chen, R Collepardo-Guevara, J van Hest, P St George-Hyslop, D Weitz, J Espinosa, T Knowles
(2024)
(doi: 10.1101/2024.11.15.623768)
Organization of the Proteostasis Network of Membraneless Organelles
C Lim, Y Bian, A González Díaz, F Pun, A Zhavoronkov, R Morimoto, M Vendruscolo
(2024)
(doi: 10.1101/2024.11.12.623332)

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