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Centre for Misfolding Diseases

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  • Currently displaying 1 - 20 of 1647 publications
A microfluidic diffusion platform for characterizing the size of lipid vesicles and the thermodynamics of protein-lipid interactions.
H Gang, C Galvagnion, G Meisl, T Müller, AK Buell, A Levin, CM Dobson, B-Z Mu, TPJ Knowles
– Anal Chem
(2018)
Hsp70 inhibits the nucleation and elongation of tau and sequesters tau aggregates with high affinity.
F Kundel, S De, P Flagmeier, MH Horrocks, M Kjaergaard, SL Shammas, SE Jackson, CM Dobson, D Klenerman
– ACS Chem Biol
(2018)
Microfluidics for protein biophysics.
J Charmet, P Arosio, TPJ Knowles
– Journal of molecular biology
(2017)
Structural basis of membrane disruption and cellular toxicity by alpha-synuclein oligomers
G Fusco, SW Chen, PTF Williamson, R Cascella, M Perni, JA Jarvis, C Cecchi, M Vendruscolo, F Chiti, N Cremades, L Ying, CM Dobson, A De Simone
– Science
(2017)
358,
1440
Mechanism of biosurfactant adsorption to oil/water interfaces from millisecond scale tensiometry measurements
L Kong, KL Saar, R Jacquat, L Hong, A Levin, H Gang, R Ye, B Mu, TPJ Knowles
– Interface focus
(2017)
7,
20170013
MobiDB 3.0: more annotations for intrinsic disorder, conformational diversity and interactions in proteins.
D Piovesan, F Tabaro, L Paladin, M Necci, I Micetic, C Camilloni, N Davey, Z Dosztányi, B Mészáros, AM Monzon, G Parisi, E Schad, P Sormanni, P Tompa, M Vendruscolo, WF Vranken, SCE Tosatto
– Nucleic acids research
(2017)
46,
D471
Clusterin protects neurons against intracellular proteotoxicity.
JM Gregory, DR Whiten, RA Brown, TP Barros, JR Kumita, JJ Yerbury, S Satapathy, K McDade, C Smith, LM Luheshi, CM Dobson, MR Wilson
– Acta Neuropathologica Communications
(2017)
5,
81
Application of Lysine-specific Labeling to Detect Transient Interactions Present During Human Lysozyme Amyloid Fibril Formation.
M Ahn, CA Waudby, A Bernardo-Gancedo, E De Genst, A Dhulesia, X Salvatella, J Christodoulou, CM Dobson, JR Kumita
– Scientific reports
(2017)
7,
15018
Distance dependent photoacoustics revealed through DNA nanostructures
J Joseph, KN Baumann, P Koehler, TJ Zuehlsdorff, DJ Cole, J Weber, SE Bohndiek, S Hernández-Ainsa
– Nanoscale
(2017)
9,
16193
A Role of Metastable Regions and Their Connectivity in the Inactivation of a Redox-Regulated Chaperone and Its Inter-Chaperone Crosstalk
O Rimon, O Suss, M Goldenberg, R Fassler, O Yogev, H Amartely, G Propper, A Friedler, D Reichmann
– Antioxid Redox Signal
(2017)
27,
1252
The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris
M Bonanomi, V Roffia, A De Palma, A Lombardi, FA Aprile, C Visentin, P Tortora, P Mauri, ME Regonesi
– Scientific reports
(2017)
7,
13417
Spin-polarised electrons in a one-magnet-only Mott spin junction
L De Pietro, G Bertolini, Q Peter, H Cabrera, A Vindigni, O Gürlü, D Pescia, U Ramsperger
– Scientific reports
(2017)
7,
13237
A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases.
JB Bertoldo, T Rodrigues, L Dunsmore, FA Aprile, MC Marques, LA Rosado, O Boutureira, TB Steinbrecher, W Sherman, F Corzana, H Terenzi, GJL Bernardes
– Chem
(2017)
3,
665
MARIO MOLINA
M Molina, J Fenton, K Stroobants, T Gianetti
– NATURE
(2017)
550,
S63
Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model.
J Villadiego, A Labrador-Garrido, JM Franco, M Leal-Lasarte, EJ De Genst, CM Dobson, D Pozo, JJ Toledo-Aral, C Roodveldt
– Glia
(2018)
66,
191
Thermodynamics of Polypeptide Supramolecular Assembly in the Short-Chain Limit.
TO Mason, TCT Michaels, A Levin, CM Dobson, E Gazit, TPJ Knowles, AK Buell
– Journal of the American Chemical Society
(2017)
139,
16134
Enhanced Quality Factor Label-free Biosensing with Micro-Cantilevers Integrated into Microfluidic Systems
T Kartanas, V Ostanin, PK Challa, R Daly, J Charmet, TPJ Knowles
– Anal Chem
(2017)
89,
11929
Absolute Quantification of Amyloid Propagons by Digital Microfluidics
M Pfammatter, M Andreasen, G Meisl, CG Taylor, J Adamcik, S Bolisetty, A Sánchez-Ferrer, D Klenerman, CM Dobson, R Mezzenga, TPJ Knowles, A Aguzzi, S Hornemann
– Anal Chem
(2017)
89,
12306
Hierarchical Biomolecular Emulsions Using 3-D Microfluidics with Uniform Surface Chemistry.
Z Toprakcioglu, A Levin, TPJ Knowles
– Biomacromolecules
(2017)
18,
3642
Integrative structure modeling with the Integrative Modeling Platform.
B Webb, S Viswanath, M Bonomi, R Pellarin, CH Greenberg, D Saltzberg, A Sali
– Protein Science
(2017)
27,
245