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- Currently displaying 1 - 20 of 2982 publications
Condensate partitioning governs the mechanism of action of FUS phase separation modulators
(2023)
(doi: 10.1101/2023.05.31.543137)
Towards sequence-based principles for protein phase separation predictions.
– Current Opinion in Chemical Biology
(2023)
75,
102317
(doi: 10.1016/j.cbpa.2023.102317)
Fragment merging strategies with known pyrimidine scaffolds targeting dihydrofolate reductase from Mycobacterium tuberculosis
– ChemMedChem
(2023)
e202300240
(doi: 10.1002/cmdc.202300240)
Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains.
– Proceedings of the National Academy of Sciences of the United States of America
(2023)
120,
e2216234120
(doi: 10.1073/pnas.2216234120)
Theoretical and Data-Driven Approaches for Biomolecular Condensates
– Chemical Reviews
(2023)
(doi: 10.1021/acs.chemrev.2c00586)
High-grade serous ovarian carcinoma organoids as models of chromosomal instability.
– Elife
(2023)
12,
e83867
(doi: 10.7554/elife.83867)
Unlocking the Potential of Bio‐Based Nitrogen‐Rich Furanic Platforms as Biomass Synthons
– Angew Chem Int Ed Engl
(2023)
e202304449
(doi: 10.1002/anie.202304449)
Unlocking the Potential of Bio‐Based Nitrogen‐Rich Furanic Platforms as Biomass Synthons
– Angewandte Chemie
(2023)
(doi: 10.1002/ange.202304449)
Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C–C Bond Cleavage Reactions
– J Am Chem Soc
(2023)
145,
10790
(doi: 10.1021/jacs.3c01960)
Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules.
– ACS Cent Sci
(2023)
9,
892
(doi: 10.1021/acscentsci.3c00015)
Characterization of Pairs of Toxic and Nontoxic Misfolded Protein Oligomers Elucidates the Structural Determinants of Oligomer Toxicity in Protein Misfolding Diseases.
– Accounts of chemical research
(2023)
(doi: 10.1021/acs.accounts.3c00045)
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference**
– Angewandte Chemie
(2023)
135,
(doi: 10.1002/ange.202300221)
Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis
– Chemistry (Weinheim an der Bergstrasse, Germany)
(2023)
29,
e202203868
(doi: 10.1002/chem.202203868)
Automated optimisation of solubility and conformational stability of antibodies and proteins
– Nat Commun
(2023)
14,
1937
(doi: 10.1038/s41467-023-37668-6)
Automated optimisation of solubility and conformational stability of antibodies and proteins
– Nature Communications
(2023)
14,
1937
(doi: 10.1038/s41467-023-37668-6)
Surface patches induce nonspecific binding and phase separation of antibodies.
– Proc Natl Acad Sci U S A
(2023)
120,
e2210332120
(doi: 10.1073/pnas.2210332120)
FuzPred: a web server for the sequence-based prediction of the context-dependent binding modes of proteins.
– Nucleic acids research
(2023)
gkad214
(doi: 10.1093/nar/gkad214)
Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins
– Nature methods
(2023)
20,
523
(doi: 10.1038/s41592-023-01807-0)