Centre for Misfolding Diseases

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  • Currently displaying 1 - 20 of 2480 publications
Author(s)
Publication title
Journal Name
Publication year
Preserving Native Cellulose–Xylan Architecture Enables Structure–Property Control in Holocellulose Nanofibrils and High-Performance Sustainable Materials
PK Deralia, R Cresswell, Y Yoshimi, T Kuga, A Echevarría-Poza, P Howell, A Dickson, MJ Le Guen, E Wagner, ACS de Alcântara, CGT Batista, N Follain, A Miller, M Vendruscolo, SJ Hill, J Beaugrand, MS Skaf, DJ Cosgrove, SP Brown, JA Elliott, R Dupree, P Dupree
(2026)
(doi: 10.64898/2026.06.07.730583)
Dynamic palladium speciation governs prodrug activation by nanoparticles in vitro and in vivo
E Latocheski, GMD Forno, JP Agnes, J Konč, A Zanotto-Filho, GJL Bernardes, JB Domingos
Colloids and Surfaces B: Biointerfaces
(2026)
267
(doi: 10.1016/j.colsurfb.2026.115902)
Many-body Interaction Competition Drives Reentrant Phase Transitions
J Qiao, RM Scrutton, D Qian, TPJ Knowles
(2026)
(doi: 10.64898/2026.05.26.727925)
Prediction of antibody non-specificity using protein language models and biophysical parameters.
LI Sakhnini, L Beltrame, S Fulle, P Sormanni, A Henriksen, N Lorenzen, M Vendruscolo, D Granata
Mabs
(2026)
18
(doi: 10.1080/19420862.2026.2678000)
Phosphorylation tunes strain-specific protein condensation during rotavirus replication organelle assembly.
J Acker, X Wang, AJ Pardal, D Desirò, T Agarwal, A Colyer, A Tollervey, R Scrutton, C Haller, L Sherry, KL Saar, K Fominykh, MLLY Johncock, SH Chong, R Murray, J Terry, JD Schmit, AN Calabrese, TPJ Knowles, A Borodavka
The EMBO Journal
(2026)
(doi: 10.1038/s44318-026-00814-z)
Effects of PTMs on Tau Protein Aggregation: Insights from HCG and Atomistic MD Simulations
A Louet, J Stuke, L Pietrek, M Vendruscolo, G Hummer
(2026)
(doi: 10.64898/2026.05.22.727278)
Does the sequence of a disordered protein encode small molecule binding paths?
A Louet, G Hummer, M Vendruscolo
(2026)
(doi: 10.64898/2026.05.20.726646)
In vitro and in vivo inhibition of amyloid β aggregation by a Ru(ii)-naphthalene diimide complex
MA Tiburcio, MP Cali, LMB Pereira, AE Graminha, I Atienza-Navarro, M Vendruscolo, M Garcia-Alloza, RM Carlos
Dalton Transactions
(2026)
55
(doi: 10.1039/d5dt02853a)
Regulatory T cells sabotage anti-tumor γδ T cells by creating IL-2-deficient environments.
R Blanco-Domínguez, AM Vaz-Pinto, L Barros, N Lopes, B Henriques-Alves, M Carreira, C Labão-Almeida, JC Ribot, GJL Bernardes, B Silva-Santos, S Mensurado
Journal of Experimental Medicine
(2026)
223
(doi: 10.1084/jem.20252133)
Molecular origins of opalescence and phase separation in mAb formulations and their relation to aggregation
I Brakti, S Lenton, M Polimeni, H Ausserwöger, R Scrutton, A Henriksen, N Lorenzen, MN Pedersen, JS Marino, F Herranz-Trillo, AE Terry, TPJ Knowles, M Groenning, V Foderà
Communications Chemistry
(2026)
(doi: 10.1038/s42004-026-02056-w)
Tracer-free Contactless Acoustic Microrheometry Quantifies Viscoelastic Spectrum of Phase-separated Condensates
K Nakajima, T Yoshikawa, Y Suzuki, S Nakatani, K Adachi, N Nakamura, S Murayama, H Sakuta, N Yangisawa, NA Erkamp, T Sneideris, M Fukuyama, M Taniguchi, M Yanagisawa, H Ogi, TPJ Knowles
(2026)
(doi: 10.48550/arxiv.2605.11660)
In vitro liquid-liquid phase separation induced by respiratory syncytial virus proteins and RNA
V Basse, T Agarwal, T Sneideris, C-A Richard, J Troussier, J-J Vasseur, F Debart, J-F Eléouët, E de Csillery, T Knowles, M Galloux
Sci Adv
(2026)
12
(doi: 10.1126/sciadv.aee2110)
Glutathione-Responsive Fragmentation of Heteronorbornadiene-Based Thiovinyl Sulfones in Glioma Cells
M Carranza, AT Carmona, E Gil de Montes, Y Méndez, I Černauskienė, GJL Bernardes, AJ Moreno-Vargas
Bioconjug Chem
(2026)
37
(doi: 10.1021/acs.bioconjchem.5c00581)
The role of N-terminal acetylation on biomolecular condensation.
C G Oliveira, MTS Silva, E Kava, T Agarwal, G Cereghetti, E F Vicente, TPJ Knowles, AJ Costa-Filho, LFS Mendes
Communications chemistry
(2026)
(doi: 10.1038/s42004-026-01975-y)
Spatially patterned, spectral single-molecule microscopy
JS Beckwith, B Cullinane, DF Heraghty, S Krokowski, CL Jones, S Yang, RC Gregory, RA Floto, AM Santos, SJ Davis, M Vendruscolo, D Klenerman, V Lindo, PK Sankaran, SF Lee
(2026)
(doi: 10.64898/2026.04.08.715690)
Microglia as transcriptional pacemakers of neuronal aging heterogeneity across individuals
CM Lim, M Vendruscolo
(2026)
(doi: 10.64898/2026.04.05.716624)
Rapid elongation drives the exceptionally fast aggregation of the most common localized human amyloid medin
V Roy Chowdhury, RI Horne, MP Cali, Z Toprakcioglu, S Linse, M Vendruscolo
Communications chemistry
(2026)
9
(doi: 10.1038/s42004-026-01950-7)
Nucleation Kinetics Reveals a Distinct Biological Function Space of Biomolecular Condensates.
L-T Deck, SN Pacheco, H Ausserwöger, D Frenkel, NA Erkamp, TPJ Knowles
Advanced Science
(2026)
13
(doi: 10.1002/advs.202522585)
Deep learning assessment of nativeness and pairing likelihood for antibody and nanobody design with AbNatiV2
A Ramon, N Frassetto, H Zhao, X Xu, M Greenig, S Onuoha, P Sormanni
Mabs
(2026)
18
(doi: 10.1080/19420862.2026.2646361)
Discovery of first-in-class YTHDC1 small molecule inhibitors for the treatment of MYC-driven cancers
RC Centore, M Charles, M Arora, M Rebmann, MJ Rawling, J Cattin, X Yang, E Batchelor, M Watson, N Bharatham, A Howarth, S Qamar, L Andraghetti, A Seeber, MG Kharas, S Cohen, M Kulander, T Knowles, S Arora
Cancer Research
(2026)
86
(doi: 10.1158/1538-7445.am2026-7101)
Yusuf Hamied Department of Chemistry
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