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Centre for Misfolding Diseases

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  • Currently displaying 1 - 20 of 3085 publications
A library‐derived peptide inhibitor of the BZLF1 transcription factor
SK Madden, A Brennan, JM Mason
– Journal of Peptide Science
(2023)
e3557
(doi: 10.1002/psc.3557)
Sequence-based drug design using transformers
S Zhang, D Huo, RI Horne, Y Qi, SP Ojeda, A Yan, M Vendruscolo
(2023)
(doi: 10.1101/2023.11.27.568880)
Polyglucosan body density in the aged mouse hippocampus is controlled by a novel modifier locus on chromosome 1
A Gómez-Pascual, DM Glikman, HX Ng, JE Tomkins, L Lu, Y Xu, DG Ashbrook, C Kaczorowski, G Kempermann, J Killmar, K Mozhui, R Aebersold, EG Williams, RW Williams, RW Overall, M Jucker, DEM de Bakker
(2023)
(doi: 10.1101/2023.11.22.567373)
CryoENsemble - a Bayesian approach for reweighting biomolecular structural ensembles using heterogeneous cryo-EM maps
T Włodarski, J Streit, A Mitropoulou, L Cabrita, M Vendruscolo, J Christodoulou
(2023)
(doi: 10.1101/2023.11.21.567999)
Sequence-based prediction of the intrinsic solubility of peptides containing non-natural amino acids.
M Oeller, RJD Kang, HL Bolt, AL Gomes Dos Santos, AL Weinmann, A Nikitidis, P Zlatoidsky, W Su, W Czechtizky, L De Maria, P Sormanni, M Vendruscolo
– Nature communications
(2023)
14,
7475
(doi: 10.1038/s41467-023-42940-w)
Multiplexed Digital Characterization of Misfolded Protein Oligomers via Solid-State Nanopores.
SE Sandler, RI Horne, S Rocchetti, R Novak, N-S Hsu, M Castellana Cruz, Z Faidon Brotzakis, RC Gregory, S Chia, GJL Bernardes, UF Keyser, M Vendruscolo
– Journal of the American Chemical Society
(2023)
145,
25776
(doi: 10.1021/jacs.3c09335)
Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes.
R Ren, S Cai, X Fang, X Wang, Z Zhang, M Damiani, C Hudlerova, A Rosa, J Hope, NJ Cook, P Gorelkin, A Erofeev, P Novak, A Badhan, M Crone, P Freemont, GP Taylor, L Tang, C Edwards, A Shevchuk, P Cherepanov, Z Luo, W Tan, Y Korchev, AP Ivanov, JB Edel
– Nat Commun
(2023)
14,
7362
(doi: 10.1038/s41467-023-43004-9)
Targeting nucleic acid phase transitions as a mechanism of action for antimicrobial peptides
T Sneideris, NA Erkamp, H Ausserwöger, KL Saar, TJ Welsh, D Qian, K Katsuya-Gaviria, MLLY Johncock, G Krainer, A Borodavka, TPJ Knowles
– Nature Communications
(2023)
14,
7170
(doi: 10.1038/s41467-023-42374-4)
Linking modulation of bio-molecular phase behaviour with collective interactions
D Qian, H Ausserwoger, W Arter, R Scrutton, T Welsh, T Kartanas, N Ermann, S Qamar, C Fischer, T Sneideris, P St George-Hyslop, R Pappu, T Knowles
(2023)
(doi: 10.1101/2023.11.02.565376)
SDS-PAGE v1
A Röntgen
(2023)
(doi: 10.17504/protocols.io.4r3l22er4l1y/v1)
Cell culture v1
A Röntgen
(2023)
(doi: 10.17504/protocols.io.36wgq3bk5lk5/v1)
MTT assay v1
A Röntgen
(2023)
(doi: 10.17504/protocols.io.e6nvwdoqwlmk/v1)
TEM v1
A Röntgen
(2023)
(doi: 10.17504/protocols.io.q26g7pd79gwz/v1)
FTIR v1
A Röntgen
(2023)
(doi: 10.17504/protocols.io.dm6gp3xqpvzp/v1)
Merging the Isonitrile‐Tetrazine (4+1) Cycloaddition and the Ugi Four‐Component Reaction into a Single Multicomponent Process
Y Méndez, AV Vasco, G Ivey, AL Dias, P Gierth, BB Sousa, CD Navo, A Torres‐Mozas, T Rodrigues, G Jiménez‐Osés, GJL Bernardes
– Angewandte Chemie
(2023)
135,
(doi: 10.1002/ange.202311186)
Merging the Isonitrile‐Tetrazine (4+1) Cycloaddition and the Ugi Four‐Component Reaction into a Single Multicomponent Process
Y Méndez, AV Vasco, G Ivey, AL Dias, P Gierth, BB Sousa, CD Navo, A Torres-Mozas, T Rodrigues, G Jiménez-Osés, GJL Bernardes
– Angew Chem Int Ed Engl
(2023)
62,
e202311186
(doi: 10.1002/anie.202311186)
Molecular mechanism of α-synuclein aggregation on lipid membranes revealed
AJ Dear, X Teng, SR Ball, J Lewin, RI Horne, D Clow, N Harper, K Yahya, TCT Michaels, S Linse, TPJ Knowles, X Yang, SC Brewerton, J Thomson, J Habchi, G Meisl
(2023)
(doi: 10.1101/2023.10.20.563279)
An automated single-molecule FRET platform for high-content, multiwell plate screening of biomolecular conformations and dynamics.
A Hartmann, K Sreenivasa, M Schenkel, N Chamachi, P Schake, G Krainer, M Schlierf
– Nature Communications
(2023)
14,
6511
(doi: 10.1038/s41467-023-42232-3)
Phase Separation and Fibrillization of Human Annexin A7 Are Mediated by Its Proline-Rich Domain.
C Yu, SL Nelson, G Meisl, R Ghirlando, L Deshmukh
– Biochemistry
(2023)
62,
3036
(doi: 10.1021/acs.biochem.3c00349)
Atomic force microscopy methods to study protein phase transitions
A Miller
(2023)
(doi: 10.17863/CAM.104325)

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