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Centre for Misfolding Diseases

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  • Currently displaying 1 - 20 of 2138 publications
Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform.
M Koopman, Q Peter, RI Seinstra, M Perni, M Vendruscolo, CM Dobson, TPJ Knowles, EAA Nollen
– Nat Protoc
(2020)
1
Kinetic diversity of amyloid oligomers
AJ Dear, TCT Michaels, G Meisl, D Klenerman, S Wu, S Perrett, S Linse, CM Dobson, TPJ Knowles
– Proc Natl Acad Sci U S A
(2020)
201922267
ThX – a next-generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee
– Chemical Science
(2020)
11,
4578
A Microfluidic Co-Flow Route for Human Serum Albumin-drugnanoparticle assembly
TA Hakala, S Davies, Z Toprakcioglu, B Bernardim, GJL Bernardes, TPJ Knowles
– Chemistry – A European Journal
(2020)
26,
5965
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
G Krainer, T Welsh, J Joseph, J Espinosa, ED Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, M Czekalska, W Arter, PS George-Hyslop, R Collepardo-Guevara, S Alberti, TPJ Knowles
(2020)
Complexity in Lipid Membrane Composition Induces Resilience to Aβ42 Aggregation
M Sanguanini, KN Baumann, S Preet, S Chia, J Habchi, TPJ Knowles, M Vendruscolo
– ACS chemical neuroscience
(2020)
11,
1347
Author Correction: Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide.
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, CM Dobson, M Vendruscolo, S Linse, TPJ Knowles
– Nat Chem
(2020)
12,
497
Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide.
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, CM Dobson, M Vendruscolo, S Linse, TPJ Knowles
– Nature Chemistry
(2020)
12,
445
Single particle zeta-potential measurements reveal the role of electrostatics in protein condensate stability
T Welsh, G Krainer, J Espinosa, J Joseph, A Sridhar, M Jahnel, W Arter, K Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
(2020)
Digital Sensing and Molecular Computation by an Enzyme-Free DNA Circuit.
WE Arter, Y Yusim, Q Peter, CG Taylor, D Klenerman, UF Keyser, TPJ Knowles
– ACS Nano
(2020)
acsnano.0c00628
Mechanism of droplet-formation in a supersonic microfluidic spray device
T Kartanas, Z Toprakcioglu, TA Hakala, A Levin, TW Herling, R Daly, J Charmet, TPJ Knowles
– Applied Physics Letters
(2020)
116,
153702
Microfluidic approaches for the analysis of protein-protein interactions in solution.
WE Arter, A Levin, G Krainer, TPJ Knowles
– Biophysical Reviews
(2020)
12,
575
Effects of sedimentation, microgravity, hydrodynamic mixing and air–water interface on α-synuclein amyloid formation
J Zhou, FS Ruggeri, MR Zimmermann, G Meisl, G Longo, SK Sekatskii, TPJ Knowles, G Dietler
– Chemical Science
(2020)
11,
3687
The molecular processes underpinning prion-like spreading and seed amplification in protein aggregation.
G Meisl, TP Knowles, D Klenerman
– Current Opinion in Neurobiology
(2020)
61,
58
Correction: Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions.
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GJL Bernandes, TPJ Knowles
– Soft matter
(2020)
16,
3586
The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils.
FS Ruggeri, P Flagmeier, JR Kumita, G Meisl, DY Chirgadze, MN Bongiovanni, TPJ Knowles, CM Dobson
– ACS Nano
(2020)
acsnano.9b09676
Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions.
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GGL Bernandes, TPJ Knowles
– Soft Matter
(2020)
16,
3082
A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation.
R Kundra, CM Dobson, M Vendruscolo
– iScience
(2020)
23,
100934
Sequence-Based Prediction of Fuzzy Protein Interactions.
M Miskei, A Horvath, M Vendruscolo, M Fuxreiter
– J Mol Biol
(2020)
432,
2289
Autoantibodies against the prion protein in individuals with PRNP mutations
K Frontzek, M Carta, M Losa, M Epskamp, G Meisl, A Anane, J-P Brandel, U Camenisch, J Castilla, S Haïk, T Knowles, E Lindner, A Lutterotti, EV Minikel, I Roiter, JG Safar, R Sanchez-Valle, D Žáková, S Hornemann, A Aguzzi, THAUTAN-MC Study Group
– Neurology
(2020)
10.1212/wnl.0000000000009183