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  • Currently displaying 1 - 20 of 3415 publications
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates
NA Erkamp, M Farag, Y Qiu, D Qian, T Sneideris, T Wu, TJ Welsh, H Ausserwöger, TJ Krug, G Chauhan, DA Weitz, MD Lew, TPJ Knowles, RV Pappu
– Nature Communications
(2025)
16,
3463
(doi: 10.1038/s41467-025-58736-z)
Scaling relations of multicomponent phase coexistence boundaries
D Qian, J Acker, RM Scrutton, CM Fischer, S Qamar, T Sneideris, A Borodavka, TPJ Knowles
(2025)
(doi: 10.1101/2025.04.02.645070)
Linking Aβ and tau in the amyloid cascade through the intersection of their proteostasis networks
CM Lim, J Hardy, M Vendruscolo
(2025)
(doi: 10.1101/2025.03.28.646065)
Serial amplification of tau filaments using Alzheimer’s brain homogenates and C322A or C322S recombinant tau
A Santambrogio, S Lövestam, MA Metrick, TS Lohr, P Xu, B Caughey, SHW Scheres, M Vendruscolo
(2025)
(doi: 10.1101/2025.03.29.646137)
Learning the rules of peptide self-assembly through data mining with large language models.
Z Yang, SK Yorke, TPJ Knowles, MJ Buehler
– Science Advances
(2025)
11,
eadv1971
(doi: 10.1126/sciadv.adv1971)
Natural aminosterols inhibit NMDA receptors with low nanomolar potency
G Fani, E Coppi, S Errico, F Cherchi, M Gennari, D Barbut, M Vendruscolo, M Zasloff, AM Pugliese, F Chiti
– FEBS Journal
(2025)
(doi: 10.1111/febs.70072)
Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen.
Y Yao, N Erkamp, T Sneideris, X Yang, R Scrutton, MM Schneider, CM Fischer, E Schoenmakers, N Schoenmakers, TPJ Knowles
– Communications biology
(2025)
8,
466
(doi: 10.1038/s42003-025-07909-z)
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes
J Nixon-Abell, FS Ruggeri, S Qamar, TW Herling, MA Czekalska, Y Shen, G Wang, C King, MS Fernandopulle, T Sneideris, JL Watson, VVS Pillai, W Meadows, JW Henderson, JE Chambers, JL Wagstaff, SH Williams, H Coyle, G Šneiderienė, Y Lu, S Zhang, SJ Marciniak, SMV Freund, E Derivery, ME Ward, M Vendruscolo, TPJ Knowles, P St George-Hyslop
– Nature communications
(2025)
16,
2814
(doi: 10.1038/s41467-025-58142-5)
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes
J Nixon-Abell, FS Ruggeri, S Qamar, TW Herling, MA Czekalska, Y Shen, G Wang, C King, MS Fernandopulle, T Sneideris, JL Watson, VVS Pillai, W Meadows, JW Henderson, JE Chambers, JL Wagstaff, SH Williams, H Coyle, G Šneiderienė, Y Lu, S Zhang, SJ Marciniak, SMV Freund, E Derivery, ME Ward, M Vendruscolo, TPJ Knowles, P St George-Hyslop
– Nature Communications
(2025)
16,
2814
(doi: 10.1038/s41467-025-58142-5)
Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen
Y Yao, N Erkamp, T Sneideris, X Yang, R Scrutton, MM Schneider, CM Fischer, E Schoenmakers, N Schoenmakers, TPJ Knowles
– Communications Biology
(2025)
8,
466
(doi: 10.1038/s42003-025-07909-z)
The α-Synuclein Proteostasis Network and its Translational Applications in Parkinson’s disease
CM Lim, M Vendruscolo
(2025)
(doi: 10.1101/2025.03.17.643594)
Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups
G Lopes Bernardes, B Gless, E Jones
– Angewandte Chemie International Edition
(2025)
(doi: 10.1002/ange.202502268)
Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay
A Santambrogio, RI Horne, MA Metrick, ZF Brotzakis, D Rinauro, E Vourkou, K Papanikolopoulou, EMC Skoulakis, S Linse, B Caughey, M Vendruscolo
(2025)
(doi: 10.1101/2025.03.09.642189)
Ganglioside lipids inhibit the aggregation of the Alzheimer's amyloid-β peptide
Z Toprakcioglu, AK Jayaram, TPJ Knowles
– RSC Chemical Biology
(2025)
(doi: 10.1039/d4cb00189c)
The SpyBLI cell-free pipeline for the rapid quantification of binding kinetics from crude samples
O Predeina, M Atkinson, O Wissett, M Ali, C Visentin, S Ricagno, AH Keeble, MR Howarth, P Sormanni
(2025)
(doi: 10.1101/2025.03.06.641810)
Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity.
M Wang, P Medarametla, T Kronenberger, T Deingruber, P Brear, W Figueroa, P-M Ho, T Krueger, JC Pearce, A Poso, JG Wakefield, DR Spring, M Welch
– Nature communications
(2025)
16,
2334
(doi: 10.1038/s41467-025-57532-z)
Phase transitions in the rolling of irregular cylinders and spheres
D Qian, Y Jung, L Mahadevan
– Proc Natl Acad Sci U S A
(2025)
122,
e2417161122
(doi: 10.1073/pnas.2417161122)
Detection of protein oligomers with nanopores.
RI Horne, SE Sandler, M Vendruscolo, UF Keyser
– Nat Rev Chem
(2025)
1
(doi: 10.1038/s41570-025-00694-7)
PLUMED Tutorials: A collaborative, community-driven learning ecosystem
GA Tribello, M Bonomi, G Bussi, C Camilloni, BI Armstrong, A Arsiccio, S Aureli, F Ballabio, M Bernetti, L Bonati, SGH Brookes, ZF Brotzakis, R Capelli, M Ceriotti, K-T Chan, P Cossio, S Dasetty, D Donadio, B Ensing, AL Ferguson, G Fraux, JD Gale, FL Gervasio, T Giorgino, NSM Herringer, GM Hocky, SE Hoff, M Invernizzi, O Languin-Cattoën, V Leone, V Limongelli, O Lopez-Acevedo, F Marinelli, P Febrer Martinez, M Masetti, S Mehdi, A Michaelides, MH Murtada, M Parrinello, PM Piaggi, A Pietropaolo, F Pietrucci, S Pipolo, C Pritchard, P Raiteri, S Raniolo, D Rapetti, V Rizzi, J Rydzewski, M Salvalaglio, C Schran, A Seal, A Shayesteh Zadeh, TFD Silva, V Spiwok, G Stirnemann, D Sucerquia, P Tiwary, O Valsson, M Vendruscolo, GA Voth, AD White, J Wu
– J Chem Phys
(2025)
162,
092501
(doi: 10.1063/5.0251501)
A Highly-Active Chemodynamic Agent Based on In Situ Generated Copper Complexes from Copper Hexacyanoferrate Nanoparticles.
J Bonet-Aleta, JL Hueso, A Valls-Chiva, I Ruiz-Aranda, B Manzanilla, JI Garcia-Peiro, S Aina, E Urriolabeitia, JV Alegre-Requena, J Santamaria
– Small (Weinheim an der Bergstrasse, Germany)
(2025)
21,
e2412355
(doi: 10.1002/smll.202412355)

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