Centre for Misfolding Diseases

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  • Currently displaying 1061 - 1080 of 2489 publications
Author(s)
Publication title
Journal Name
Publication year
Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species
L-M Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, M Rodrigues, CM Dobson, S Ghandi, SE Bohndiek, TN Snaddon, SF Lee
R Soc Open Sci
(2018)
5
(doi: 10.1098/rsos.171399)
Optical Structural Analysis of Individual α-Synuclein Oligomers.
JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, D Klenerman, SF Lee
Angewandte Chemie (International ed. in English)
(2018)
57
(doi: 10.1002/anie.201710779)
Microfluidic Diffusion Platform for Characterizing the Sizes of Lipid Vesicles and the Thermodynamics of Protein–Lipid Interactions
H Gang, C Galvagnion, G Meisl, T Müller, M Pfammatter, AK Buell, A Levin, CM Dobson, B Mu, TPJ Knowles
Analytical chemistry
(2018)
90
(doi: 10.1021/acs.analchem.7b04820)
Secondary nucleation in amyloid formation.
M Törnquist, TCT Michaels, K Sanagavarapu, X Yang, G Meisl, SIA Cohen, TPJ Knowles, S Linse
Chemical Communications
(2018)
54
(doi: 10.1039/c8cc02204f)
Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils.
JWP Brown, G Meisl, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion
Chemical communications (Cambridge, England)
(2018)
54
(doi: 10.1039/c8cc03002b)
A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis
KR Scroggie, LJ Alcock, MJ Matos, GJL Bernardes, MV Perkins, JM Chalker
Peptide Science
(2018)
110
(doi: 10.1002/pep2.24069)
A fluorogenic probe for cell surface phosphatidylserine using an intramolecular indicator displacement sensing mechanism
VE Zwicker, BL Oliveira, JH Yeo, ST Fraser, GJL Bernardes, EJ New, KA Jolliffe
Angewandte Chemie (International ed. in English)
(2018)
58
(doi: 10.1002/anie.201812489)
Enhancing power density of biophotovoltaics by decoupling storage and power delivery
KL Saar, P Bombelli, DJ Lea-Smith, T Call, E-M Aro, T Müller, CJ Howe, TPJ Knowles
Nature Energy
(2018)
3
(doi: 10.1038/s41560-017-0073-0)
On-chip measurements of protein unfolding from direct observations of micron-scale diffusion
Y Zhang, EV Yates, L Hong, KL Saar, G Meisl, CM Dobson, TPJ Knowles
Chemical Science
(2018)
9
(doi: 10.1039/c7sc04331g)
Glaucoma as a protein misfolding disease: an investigation of its metastable proteome
P Joshi, M Vendruscolo
JOURNAL OF ALZHEIMERS DISEASE
(2018)
64
Microfluidic approaches for probing amyloid assembly and behaviour
TW Herling, A Levin, KL Saar, CM Dobson, TPJ Knowles
Lab on a Chip - Miniaturisation for Chemistry and Biology
(2018)
18
(doi: 10.1039/c7lc01241a)
Development of Antibody-Directed Therapies: Quo Vadis?
T Rodrigues, GJL Bernardes
Angew Chem Int Ed Engl
(2018)
57
(doi: 10.1002/anie.201712185)
Third generation antibody discovery methods: in silico rational design
P Sormanni, FA Aprile, M Vendruscolo
Chem Soc Rev
(2018)
47
(doi: 10.1039/c8cs00523k)
A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging.
BJ Stenton, BL Oliveira, MJ Matos, L Sinatra, GJL Bernardes
Chemical Science
(2018)
9
(doi: 10.1039/c8sc00256h)
Observation of molecular self-assembly events in massively parallel microdroplet arrays.
Z Toprakcioglu, PK Challa, A Levin, TPJ Knowles
Lab Chip
(2018)
18
(doi: 10.1039/c8lc00862k)
Microfluidics for Protein Biophysics.
J Charmet, P Arosio, TPJ Knowles
Journal of Molecular Biology
(2017)
430
(doi: 10.1016/j.jmb.2017.12.015)
The use of fluoroproline in MUC1 antigen enables efficient detection of antibodies in patients with prostate cancer
VJ Somovilla, IA Bermejo, IS Albuquerque, N Martínez-Sáez, J Castro-López, F García-Martín, I Compañón, H Hinou, S Nishimura, J Jiménez-Barbero, JL Asensio, A Avenoza, JH Busto,, R Hurtado-Guerrero, JM Peregrina, GJ Lopes Bernardes, F Corzana1
J Am Chem Soc
(2017)
139
(doi: 10.1021/jacs.7b09447)
Structural basis of membrane disruption and cellular toxicity by a-synuclein oligomers
G Fusco, SW Chen, PTF Williamson, R Cascella, M Perni, JA Jarvis, C Cecchi, M Vendruscolo, F Chiti, N Cremades, L Ying, CM Dobson, A De Simone
Science (New York, N.Y.)
(2017)
358
(doi: 10.1126/science.aan6160)
Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation
AM Freedy, MJ Matos, O Boutureira, F Corzana, A Guerreiro, P Akkapeddi, VJ Somovilla, T Rodrigues, K Nicholls, B Xie, G Jiménez-Osés, KM Brindle, AA Neves, GJL Bernardes
Journal of the American Chemical Society
(2017)
139
(doi: 10.1021/jacs.7b10702)
Inhibiting the Ca<sup>2+</sup> Influx Induced by Human CSF.
A Drews, S De, P Flagmeier, DC Wirthensohn, W-H Chen, DR Whiten, M Rodrigues, C Vincke, S Muyldermans, RW Paterson, CF Slattery, NC Fox, JM Schott, H Zetterberg, CM Dobson, S Gandhi, D Klenerman
Cell Rep
(2017)
21
(doi: 10.1016/j.celrep.2017.11.057)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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