Centre for Misfolding Diseases

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  • Currently displaying 1061 - 1080 of 2403 publications
Author(s)
Publication title
Journal Name
Publication year
Plagues and History: From the Black Death to Alzheimer's Disease
C Dobson, M Dobson
(2017)
(doi: 10.1017/9781108147910.004)
A natural product inhibits the initiation of α-synuclein aggregation & suppresses its toxicity
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
Proceedings of the National Academy of Sciences
(2017)
114
(doi: 10.1073/pnas.1610586114)
Attenuating the Toxicity of Amyloid-Beta Aggregation with Specific Species
R Limbocker, B Mannini, M Perni, S Chia, G Heller, FS Ruggeri, J Habchi, G Meisl, PK Challa, M Zasloff, TPJ Knowles, M Vendruscolo, CM Dobson
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.2673)
Structural Investigation of an Immunoglobulin Domain on the Ribosome using NMR Spectroscopy
AME Cassaignau, HMM Launay, CA Waudby, T Wlodarski, M-E Karyadi, AL Robertson, X Wang, C Camilloni, M Vendruscolo, CA Woolhead, L Cabrita, J Christodoulou
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.258)
Effects of Amyloid-Beta Expression on Neuronal Signalling Pathways in a Novel C. elegans Model of Alzheimer's Disease
T Sinnige, P Ciryam, CM Dobson, M de Bono, M Vendruscolo
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.878)
Characterization of Protein Kinase a Free Energy Landscape by NMR-Restrained Metadynamics
Y Wang, C Camilloni, J Kim, M Vendruscolo, J Gao, G Veglia
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.310)
Simultaneous NMR characterisation of multiple minima in the free energy landscape of an RNA UUCG tetraloop.
AN Borkar, P Vallurupalli, C Camilloni, LE Kay, M Vendruscolo
Physical chemistry chemical physics : PCCP
(2017)
19
(doi: 10.1039/c6cp08313g)
Networks of Dynamic Allostery Regulate Enzyme Function
MJ Holliday, C Camilloni, GS Armstrong, M Vendruscolo, EZ Eisenmesser
Structure (London, England : 1993)
(2017)
25
(doi: 10.1016/j.str.2016.12.003)
Site-selective installation of BASHY fluorescent dyes to Annexin V for targeted detection of apoptotic cells.
PMSD Cal, F Sieglitz, FMF Santos, C Parente Carvalho, A Guerreiro, JB Bertoldo, U Pischel, PMP Gois, GJL Bernardes
Chemical communications (Cambridge, England)
(2017)
53
(doi: 10.1039/c6cc08671c)
Principles of protein structural ensemble determination.
M Bonomi, GT Heller, C Camilloni, M Vendruscolo
Current opinion in structural biology
(2017)
42
(doi: 10.1016/j.sbi.2016.12.004)
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells
E Jiménez‐Moreno, Z Guo, BL Oliveira, IS Albuquerque, A Kitowski, A Guerreiro, O Boutureira, T Rodrigues, G Jiménez‐Osés, GJL Bernardes
Angewandte Chemie
(2017)
129
(doi: 10.1002/ange.201609607)
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells.
E Jiménez-Moreno, Z Guo, BL Oliveira, IS Albuquerque, A Kitowski, A Guerreiro, O Boutureira, T Rodrigues, G Jiménez-Osés, GJL Bernardes
Angewandte Chemie - International Edition
(2017)
56
(doi: 10.1002/anie.201609607)
Oxidative Activation of C-S Bonds with an Electropositive Nitrogen Promoter Enables Orthogonal Glycosylation of Alkyl over Phenyl Thioglycosides.
A Kitowski, E Jiménez-Moreno, M Salvadó, J Mestre, S Castillón, G Jiménez-Osés, O Boutureira, GJL Bernardes
Org Lett
(2017)
19
(doi: 10.1021/acs.orglett.7b02886)
In situcharacterization of advanced glycation end products (AGEs) in collagen and model extracellular matrix by solid state NMR
R Li, R Rajan, WCV Wong, DG Reid, MJ Duer, VJ Somovilla, N Martinez-Saez, GJL Bernardes, R Hayward, CM Shanahan
Chemical communications (Cambridge, England)
(2017)
53
(doi: 10.1039/c7cc06624d)
Kinetics of protein aggregation
T Knowles
FEBS JOURNAL
(2017)
284
A microfluidic platform for quantitative protein studies
TW Herling, P Arosio, T Mueller, DJ O'Connell, MC Bauer, J Persson, U Weininger, S Linse, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Single amyloid aggregates chemical and structural analysis by infrared nanospectroscopy
FS Ruggeri, J Habchi, C Sean, M Vendruscolo, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products.
KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, X Yang, S Linse, TPJ Knowles
Lab on a chip
(2017)
18
(doi: 10.1039/c7lc00797c)
The Amyloid Phenomenon and Its Links with Human Disease
CM Dobson
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
(2017)
9
(doi: 10.1101/cshperspect.a023648)
Secondary nucleation of monomers on fibril surface dominates $\alpha$-synuclein aggregation and provides autocatalytic amyloid amplification
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
Q Rev Biophys
(2017)
50
(doi: 10.1017/S0033583516000172)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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