Centre for Misfolding Diseases

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  • Currently displaying 1181 - 1200 of 2396 publications
Author(s)
Publication title
Journal Name
Publication year
Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions.
P Arosio, T Müller, L Rajah, EV Yates, FA Aprile, Y Zhang, SIA Cohen, DA White, TW Herling, EJ De Genst, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
ACS Nano
(2015)
10
(doi: 10.1021/acsnano.5b04713)
Using Pseudocontact Shifts and Residual Dipolar Couplings as Exact NMR Restraints for the Determination of Protein Structural Ensembles.
C Camilloni, M Vendruscolo
Biochemistry
(2015)
54
(doi: 10.1021/acs.biochem.5b01138)
Enhancing Methotrexate Tolerance with Folate Tagged Liposomes in Arthritic Mice.
E Nogueira, F Lager, D Le Roux, P Nogueira, J Freitas, C Charvet, G Renault, A Loureiro, CR Almeida, A Ohradanova-Repic, C Machacek, GJL Bernardes, A Moreira, H Stockinger, M Burnet, AM Carmo, AC Gomes, A Preto, G Bismuth, A Cavaco-Paulo
Journal of Biomedical Nanotechnology
(2015)
11
(doi: 10.1166/jbn.2015.2170)
Site-selective protein-modification chemistry for basic biology and drug development.
N Krall, FP da Cruz, O Boutureira, GJL Bernardes
Nature chemistry
(2015)
8
(doi: 10.1038/NCHEM.2393)
Consistent treatment of hydrophobicity in protein lattice models accounts for cold denaturation
E van Dijk, P Varilly, T Knowles, D Frenkel, S Abeln
(2015)
(doi: 10.48550/arxiv.1511.06590)
Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants.
L Tosatto, MH Horrocks, AJ Dear, TPJ Knowles, M Dalla Serra, N Cremades, CM Dobson, D Klenerman
Scientific reports
(2015)
5
(doi: 10.1038/srep16696)
N‑Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42
O Szczepankiewicz, B Linse, G Meisl, E Thulin, B Frohm, C Sala Frigerio, MT Colvin, AC Jacavone, RG Griffin, T Knowles, DM Walsh, S Linse
Journal of the American Chemical Society
(2015)
137
(doi: 10.1021/jacs.5b07849)
Parmbsc1: a refined force field for DNA simulations.
I Ivani, PD Dans, A Noy, A Pérez, I Faustino, A Hospital, J Walther, P Andrio, R Goñi, A Balaceanu, G Portella, F Battistini, JL Gelpí, C González, M Vendruscolo, CA Laughton, SA Harris, DA Case, M Orozco
Nat Methods
(2015)
13
(doi: 10.1038/NMETH.3658)
Structure-Free Validation of Residual Dipolar Coupling and Paramagnetic Relaxation Enhancement Measurements of Disordered Proteins.
FN Newby, A De Simone, M Yagi-Utsumi, X Salvatella, CM Dobson, M Vendruscolo
Biochemistry
(2015)
54
(doi: 10.1021/acs.biochem.5b00670)
Solvent exposure of Tyr10 as a probe of structural differences between monomeric and aggregated forms of the amyloid-β peptide.
P Aran Terol, JR Kumita, SC Hook, CM Dobson, EK Esbjörner
Biochem Biophys Res Commun
(2015)
468
(doi: 10.1016/j.bbrc.2015.11.018)
SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation.
R Zeineddine, JF Pundavela, L Corcoran, EM Stewart, D Do-Ha, M Bax, G Guillemin, KL Vine, DM Hatters, H Ecroyd, CM Dobson, BJ Turner, L Ooi, MR Wilson, NR Cashman, JJ Yerbury
Mol Neurodegener
(2015)
10
(doi: 10.1186/s13024-015-0053-4)
ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, AR Costa, RB Dodd, FTS Chan, CH Michel, D Kronenberg-Versteeg, Y Li, S-P Yang, Y Wakutani, W Meadows, RR Ferry, L Dong, GG Tartaglia, G Favrin, W-L Lin, DW Dickson, M Zhen, D Ron, G Schmitt-Ulms, PE Fraser, NA Shneider, C Holt, M Vendruscolo, CF Kaminski, P St George-Hyslop
Neuron
(2015)
88
(doi: 10.1016/j.neuron.2015.10.030)
Mapping the Protein Fold Universe Using the CamTube Force Field in Molecular Dynamics Simulations.
P Kukic, A Kannan, MJJ Dijkstra, S Abeln, C Camilloni, M Vendruscolo
PLoS Comput Biol
(2015)
11
(doi: 10.1371/journal.pcbi.1004435)
The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments.
D Granata, F Baftizadeh, J Habchi, C Galvagnion, A De Simone, C Camilloni, A Laio, M Vendruscolo
Sci Rep
(2015)
5
(doi: 10.1038/srep15449)
ChemInform Abstract: Biophysical Approaches for the Study of Interactions Between Molecular Chaperones and Protein Aggregates
MA Wright, FA Aprile, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
ChemInform
(2015)
46
(doi: 10.1002/chin.201545294)
The length distribution of frangible biofilaments
TCT Michaels, P Yde, JCW Willis, MH Jensen, D Otzen, CM Dobson, AK Buell, TPJ Knowles
J Chem Phys
(2015)
143
(doi: 10.1063/1.4933230)
Sulfur-Limonene Polysulfide: A Material Synthesized Entirely from Industrial By-Products and Its Use in Removing Toxic Metals from Water and Soil
MP Crockett, AM Evans, MJH Worthington, IS Albuquerque, AD Slattery, CT Gibson, JA Campbell, DA Lewis, GJL Bernardes, JM Chalker
Angewandte Chemie International Edition
(2015)
55
(doi: 10.1002/anie.201508708)
Targeting the N-myc oncoprotein using nanobody technology
L Kent, C Dobson, E de-Genst, H Laman
Molecular Cancer Research
(2015)
13
(doi: 10.1158/1557-3125.MYC15-B35)
Particle-based simulations of steady-state mass transport at high Péclet numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
(2015)
Particle-based simulations of steady-state mass transport at high Péclet numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
(2015)
(doi: 10.48550/arxiv.1510.05126)
Yusuf Hamied Department of Chemistry
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