Centre for Misfolding Diseases

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  • Currently displaying 1141 - 1160 of 2474 publications
Author(s)
Publication title
Journal Name
Publication year
Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species.
FA Aprile, P Arosio, G Fusco, SW Chen, JR Kumita, A Dhulesia, P Tortora, TPJ Knowles, M Vendruscolo, CM Dobson, N Cremades
Biochemistry
(2017)
56
(doi: 10.1021/acs.biochem.6b01178)
Correction for: A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity (Proceedings of the National Academy of Sciences of the United States of America (2017) 114 (E1009-E1017) DOI: 10.1073/pnas.1610586114)
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Mueller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
Proceedings of the National Academy of Sciences of the United States of America
(2017)
114
(doi: 10.1073/pnas.1701964114)
Bayesian weighing of electron cryo-microscopy data for integrative structural modeling
M Bonomi, S Hanot, CH Greenberg, A Sali, M Nilges, M Vendruscolo, R Pellarin
(2017)
(doi: 10.1101/113951)
Acceleration of α-synuclein aggregation.
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
(2017)
24
(doi: 10.1080/13506129.2017.1292904)
Widespread Proteome Remodeling and Aggregation in Aging C. elegans (vol 161, pg 919, 2015)
DM Walther, P Kasturi, M Zheng, S Pinkert, G Vecchi, P Ciryam, RI Morimoto, CM Dobson, M Vendruscolo, M Mann, FU Hartl
Cell
(2017)
168
(doi: 10.1016/j.cell.2016.12.041)
Plagues and history: From the black death to alzheimer’s disease
C Dobson, M Dobson
(2017)
(doi: 10.1017/9781108147910.004)
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
Proceedings of the National Academy of Sciences
(2017)
114
(doi: 10.1073/pnas.1610586114)
Characterization of Protein Kinase a Free Energy Landscape by NMR-Restrained Metadynamics
Y Wang, C Camilloni, J Kim, M Vendruscolo, J Gao, G Veglia
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.310)
Effects of Amyloid-Beta Expression on Neuronal Signalling Pathways in a Novel C. elegans Model of Alzheimer's Disease
T Sinnige, P Ciryam, CM Dobson, M de Bono, M Vendruscolo
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.878)
Attenuating the Toxicity of Amyloid-Beta Aggregation with Specific Species
R Limbocker, B Mannini, M Perni, S Chia, G Heller, FS Ruggeri, J Habchi, G Meisl, PK Challa, M Zasloff, TPJ Knowles, M Vendruscolo, CM Dobson
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.2673)
Structural Investigation of an Immunoglobulin Domain on the Ribosome using NMR Spectroscopy
AME Cassaignau, HMM Launay, CA Waudby, T Wlodarski, M-E Karyadi, AL Robertson, X Wang, C Camilloni, M Vendruscolo, CA Woolhead, L Cabrita, J Christodoulou
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.258)
Simultaneous NMR characterisation of multiple minima in the free energy landscape of an RNA UUCG tetraloop
AN Borkar, P Vallurupalli, C Camilloni, LE Kay, M Vendruscolo
Physical chemistry chemical physics : PCCP
(2017)
19
(doi: 10.1039/c6cp08313g)
Networks of Dynamic Allostery Regulate Enzyme Function.
MJ Holliday, C Camilloni, GS Armstrong, M Vendruscolo, EZ Eisenmesser
Structure
(2017)
25
(doi: 10.1016/j.str.2016.12.003)
Site-selective installation of BASHY fluorescent dyes to Annexin V for targeted detection of apoptotic cells.
PMSD Cal, F Sieglitz, FMF Santos, C Parente Carvalho, A Guerreiro, JB Bertoldo, U Pischel, PMP Gois, GJL Bernardes
Chem Commun (Camb)
(2017)
53
(doi: 10.1039/c6cc08671c)
Principles of protein structural ensemble determination.
M Bonomi, GT Heller, C Camilloni, M Vendruscolo
Curr Opin Struct Biol
(2017)
42
(doi: 10.1016/j.sbi.2016.12.004)
Kinetics of spontaneous filament nucleation via oligomers: insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
(2017)
(doi: 10.48550/arxiv.1610.02320)
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells
E Jiménez‐Moreno, Z Guo, BL Oliveira, IS Albuquerque, A Kitowski, A Guerreiro, O Boutureira, T Rodrigues, G Jiménez‐Osés, GJL Bernardes
Angewandte Chemie
(2017)
129
(doi: 10.1002/ange.201609607)
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells
E Jiménez-Moreno, Z Guo, BL Oliveira, IS Albuquerque, A Kitowski, A Guerreiro, O Boutureira, T Rodrigues, G Jiménez-Osés, GJL Bernardes
Angew Chem Int Ed Engl
(2017)
56
(doi: 10.1002/anie.201609607)
In situ characterization of advanced glycation end products (AGEs) in collagen and model extracellular matrix by solid state NMR.
R Li, R Rajan, WCV Wong, DG Reid, MJ Duer, VJ Somovilla, N Martinez-Saez, GJL Bernardes, R Hayward, CM Shanahan
Chemical communications (Cambridge, England)
(2017)
53
(doi: 10.1039/c7cc06624d)
Secondary nucleation of monomers on fibril surface dominates $\alpha$-synuclein aggregation and provides autocatalytic amyloid amplification
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
Q Rev Biophys
(2017)
50
(doi: 10.1017/S0033583516000172)
Yusuf Hamied Department of Chemistry
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