Centre for Misfolding Diseases

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  • Currently displaying 1101 - 1120 of 2455 publications
Author(s)
Publication title
Journal Name
Publication year
Scaling and dimensionality in the chemical kinetics of protein filament formation
TCT Michaels, AJ Dear, TPJ Knowles
International Reviews in Physical Chemistry
(2016)
35
(doi: 10.1080/0144235x.2016.1239335)
Fabrication of fibrillosomes from droplets stabilized by protein nanofibrils at all-aqueous interfaces.
Y Song, U Shimanovich, TCT Michaels, Q Ma, J Li, TPJ Knowles, HC Shum
Nat Commun
(2016)
7
(doi: 10.1038/ncomms12934)
Kinetics of spontaneous filament nucleation via oligomers: insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
(2016)
(doi: 10.48550/arxiv.1610.02320)
Elastic instability-mediated actuation by a supra-molecular polymer
A Levin, TCT Michaels, L Adler-Abramovich, TO Mason, T Müller, B Zhang, L Mahadevan, E Gazit, TPJ Knowles
Nature Physics
(2016)
12
(doi: 10.1038/nphys3808)
Intra-chain organisation of hydrophobic residues controls inter-chain aggregation rates of amphiphilic polymers
P Varilly, AP Willard, JB Kirkegaard, TPJ Knowles, D Chandler
(2016)
(doi: 10.48550/arxiv.1610.00183)
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity.
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, W-L Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, M-L Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis
Science
(2016)
354
(doi: 10.1126/science.aag1465)
Structural basis of synaptic vesicle assembly promoted by α-synuclein
G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, GS Kaminski Schierle, M Vendruscolo, G Veglia, CM Dobson, A De Simone
Nature Communications
(2016)
7
(doi: 10.1038/ncomms12563)
Kinetics of fragmentation and dissociation of two-strand protein filaments: Coarse-grained simulations and experiments
A Zaccone, I Terentjev, TW Herling, TPJ Knowles, A Aleksandrova, EM Terentjev
(2016)
(doi: 10.48550/arxiv.1609.05027)
Kinetics of fragmentation and dissociation of two-strand protein filaments: Coarse-grained simulations and experiments
A Zaccone, I Terentjev, TW Herling, TPJ Knowles, A Aleksandrova, EM Terentjev
The Journal of Chemical Physics
(2016)
145
(doi: 10.1063/1.4962366)
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases
E Evangelisti, R Cascella, M Becatti, G Marrazza, CM Dobson, F Chiti, M Stefani, C Cecchi
Sci Rep
(2016)
6
(doi: 10.1038/srep32721)
Unveiling (−)‐Englerin A as a Modulator of L‐Type Calcium Channels
T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes
Angewandte Chemie
(2016)
128
(doi: 10.1002/ange.201604336)
Physical determinants of the self-replication of protein fibrils.
A Šarić, AK Buell, G Meisl, TCT Michaels, CM Dobson, S Linse, TPJ Knowles, D Frenkel
Nat Phys
(2016)
12
(doi: 10.1038/NPHYS3828)
Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation
P Flagmeier, G Meisl, M Vendruscolo, TPJ Knowles, CM Dobson, AK Buell, C Galvagnion
Proceedings of the National Academy of Sciences of the United States of America
(2016)
113
(doi: 10.1073/pnas.1604645113)
Metadynamic metainference: Enhanced sampling of the metainference ensemble using metadynamics.
M Bonomi, C Camilloni, M Vendruscolo
Sci Rep
(2016)
6
(doi: 10.1038/srep31232)
Protein Aggregate-Ligand Binding Assays Based on Microfluidic Diffusional Separation.
Y Zhang, AK Buell, T Müller, E De Genst, J Benesch, CM Dobson, TPJ Knowles
ChemBioChem
(2016)
17
(doi: 10.1002/cbic.201600384)
Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells.
A Drews, J Flint, N Shivji, P Jönsson, D Wirthensohn, E De Genst, C Vincke, S Muyldermans, C Dobson, D Klenerman
Scientific Reports
(2016)
6
(doi: 10.1038/srep31910)
Controlling the Physical Dimensions of Peptide Nanotubes by Supramolecular Polymer Coassembly
L Adler-Abramovich, P Marco, ZA Arnon, RCG Creasey, TCT Michaels, A Levin, DJ Scurr, CJ Roberts, TPJ Knowles, SJB Tendler, E Gazit
ACS Nano
(2016)
10
(doi: 10.1021/acsnano.6b01587)
A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer's disease.
R Freer, P Sormanni, G Vecchi, P Ciryam, CM Dobson, M Vendruscolo
Science Advances
(2016)
2
(doi: 10.1126/sciadv.1600947)
Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody.
EMS Fernández, CD Navo, N Martínez-Sáez, R Gonçalves-Pereira, VJ Somovilla, A Avenoza, JH Busto, GJL Bernardes, G Jiménez-Osés, F Corzana, JMG Fernández, CO Mellet, JM Peregrina
Org Lett
(2016)
18
(doi: 10.1021/acs.orglett.6b01899)
Symptoms and patient factors associated with longer time to diagnosis for colorectal cancer: results from a prospective cohort study.
FM Walter, JD Emery, S Mendonca, N Hall, HC Morris, K Mills, C Dobson, C Bankhead, M Johnson, GA Abel, MD Rutter, W Hamilton, GP Rubin
British journal of cancer
(2016)
115
(doi: 10.1038/bjc.2016.221)
Yusuf Hamied Department of Chemistry
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