Centre for Misfolding Diseases

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  • Currently displaying 1101 - 1120 of 2396 publications
Author(s)
Publication title
Journal Name
Publication year
Bioorthogonal Strategy for Bioprocessing of Specific-Site-Functionalized Enveloped Influenza-Virus-Like Particles
SB Carvalho, JM Freire, MG Moleirinho, F Monteiro, D Gaspar, MARB Castanho, MJT Carrondo, PM Alves, GJL Bernardes, C Peixoto
Bioconjugate Chemistry
(2016)
27
(doi: 10.1021/acs.bioconjchem.6b00372)
Scaling and dimensionality in the chemical kinetics of protein filament formation
TCT Michaels, AJ Dear, TPJ Knowles
International Reviews in Physical Chemistry
(2016)
35
(doi: 10.1080/0144235X.2016.1239335)
Fabrication of fibrillosomes from droplets stabilized by protein nanofibrils at all-aqueous interfaces.
Y Song, U Shimanovich, TCT Michaels, Q Ma, J Li, TPJ Knowles, HC Shum
Nature Communications
(2016)
7
(doi: 10.1038/ncomms12934)
Kinetics of spontaneous filament nucleation via oligomers: insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
(2016)
(doi: 10.48550/arxiv.1610.02320)
Intra-chain organisation of hydrophobic residues controls inter-chain aggregation rates of amphiphilic polymers
P Varilly, AP Willard, JB Kirkegaard, TPJ Knowles, D Chandler
(2016)
(doi: 10.48550/arxiv.1610.00183)
Elastic instability-mediated actuation by a supra-molecular polymer
A Levin, TCT Michaels, L Adler-Abramovich, TO Mason, T Müller, B Zhang, L Mahadevan, E Gazit, TPJ Knowles
Nature Physics
(2016)
12
(doi: 10.1038/nphys3808)
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, W-L Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, M-L Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis
Science (New York, N.Y.)
(2016)
354
(doi: 10.1126/science.aag1465)
Structural basis of synaptic vesicle assembly promoted by α-synuclein.
G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, GS Kaminski Schierle, M Vendruscolo, G Veglia, CM Dobson, A De Simone
Nature Communications
(2016)
7
(doi: 10.1038/ncomms12563)
Kinetics of fragmentation and dissociation of two-strand protein filaments: Coarse-grained simulations and experiments
A Zaccone, I Terentjev, TW Herling, TPJ Knowles, A Aleksandrova, EM Terentjev
(2016)
(doi: 10.48550/arxiv.1609.05027)
Kinetics of fragmentation and dissociation of two-strand protein filaments: Coarse-grained simulations and experiments.
A Zaccone, I Terentjev, TW Herling, TPJ Knowles, A Aleksandrova, EM Terentjev
The Journal of Chemical Physics
(2016)
145
(doi: 10.1063/1.4962366)
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases.
E Evangelisti, R Cascella, M Becatti, G Marrazza, CM Dobson, F Chiti, M Stefani, C Cecchi
Sci Rep
(2016)
6
(doi: 10.1038/srep32721)
Unveiling (−)‐Englerin A as a Modulator of L‐Type Calcium Channels
T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes
Angewandte Chemie
(2016)
128
(doi: 10.1002/ange.201604336)
Physical determinants of the self-replication of protein fibrils.
A Šarić, AK Buell, G Meisl, TCT Michaels, CM Dobson, S Linse, TPJ Knowles, D Frenkel
Nat Phys
(2016)
12
(doi: 10.1038/nphys3828)
Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregation
P Flagmeier, G Meisl, M Vendruscolo, TPJ Knowles, CM Dobson, AK Buell, C Galvagnion
Proceedings of the National Academy of Sciences
(2016)
113
(doi: 10.1073/pnas.1604645113)
Metadynamic metainference: Enhanced sampling of the metainference ensemble using metadynamics
M Bonomi, C Camilloni, M Vendruscolo
Sci Rep
(2016)
6
(doi: 10.1038/srep31232)
Protein Aggregate‐Ligand Binding Assays Based on Microfluidic Diffusional Separation
Y Zhang, AK Buell, T Müller, E De Genst, J Benesch, CM Dobson, TPJ Knowles
Chembiochem : a European journal of chemical biology
(2016)
17
(doi: 10.1002/cbic.201600384)
Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells.
A Drews, J Flint, N Shivji, P Jönsson, D Wirthensohn, E De Genst, C Vincke, S Muyldermans, C Dobson, D Klenerman
Scientific Reports
(2016)
6
(doi: 10.1038/srep31910)
Controlling the Physical Dimensions of Peptide Nanotubes by Supramolecular Polymer Coassembly
L Adler-Abramovich, P Marco, ZA Arnon, RCG Creasey, TCT Michaels, A Levin, DJ Scurr, CJ Roberts, TPJ Knowles, SJB Tendler, E Gazit
ACS Nano
(2016)
10
(doi: 10.1021/acsnano.6b01587)
A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer's disease.
R Freer, P Sormanni, G Vecchi, P Ciryam, CM Dobson, M Vendruscolo
Science Advances
(2016)
2
(doi: 10.1126/sciadv.1600947)
Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody.
EMS Fernández, CD Navo, N Martínez-Sáez, R Gonçalves-Pereira, VJ Somovilla, A Avenoza, JH Busto, GJL Bernardes, G Jiménez-Osés, F Corzana, JMG Fernández, CO Mellet, JM Peregrina
Organic letters
(2016)
18
(doi: 10.1021/acs.orglett.6b01899)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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