Centre for Misfolding Diseases

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  • Currently displaying 1101 - 1120 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces
JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, M Vendruscolo, TPJ Knowles, CM Dobson, C Galvagnion
Scientific Reports
(2016)
6
(doi: 10.1038/srep36010)
Structural Characteristics of α-Synuclein Oligomers.
N Cremades, SW Chen, CM Dobson
Int Rev Cell Mol Biol
(2016)
329
(doi: 10.1016/bs.ircmb.2016.08.010)
Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
B Bernardim, PMSD Cal, MJ Matos, BL Oliveira, N Martínez-Sáez, IS Albuquerque, E Perkins, F Corzana, ACB Burtoloso, G Jiménez-Osés, GJL Bernardes
Nature Communications
(2016)
7
(doi: 10.1038/ncomms13128)
Dynamic microfluidic control of supramolecular peptide self-assembly
ZA Arnon, A Vitalis, A Levin, TCT Michaels, A Caflisch, TPJ Knowles, L Adler-Abramovich, E Gazit
Nature communications
(2016)
7
(doi: 10.1038/ncomms13190)
Bioorthogonal Strategy for Bioprocessing of Specific-Site-Functionalized Enveloped Influenza-Virus-Like Particles.
SB Carvalho, JM Freire, MG Moleirinho, F Monteiro, D Gaspar, MARB Castanho, MJT Carrondo, PM Alves, GJL Bernardes, C Peixoto
Bioconjug Chem
(2016)
27
(doi: 10.1021/acs.bioconjchem.6b00372)
Scaling and dimensionality in the chemical kinetics of protein filament formation
TCT Michaels, AJ Dear, TPJ Knowles
International Reviews in Physical Chemistry
(2016)
35
(doi: 10.1080/0144235x.2016.1239335)
Fabrication of fibrillosomes from droplets stabilized by protein nanofibrils at all-aqueous interfaces.
Y Song, U Shimanovich, TCT Michaels, Q Ma, J Li, TPJ Knowles, HC Shum
Nature communications
(2016)
7
(doi: 10.1038/ncomms12934)
Kinetics of spontaneous filament nucleation via oligomers: insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
(2016)
(doi: 10.48550/arxiv.1610.02320)
Intra-chain organisation of hydrophobic residues controls inter-chain aggregation rates of amphiphilic polymers
P Varilly, AP Willard, JB Kirkegaard, TPJ Knowles, D Chandler
(2016)
(doi: 10.48550/arxiv.1610.00183)
Elastic instability-mediated actuation by a supra-molecular polymer
A Levin, TCT Michaels, L Adler-Abramovich, TO Mason, T Müller, B Zhang, L Mahadevan, E Gazit, TPJ Knowles
Nature Physics
(2016)
12
(doi: 10.1038/NPHYS3808)
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, W-L Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, M-L Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis
Science
(2016)
354
(doi: 10.1126/science.aag1465)
Structural basis of synaptic vesicle assembly promoted by α-synuclein.
G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, GS Kaminski Schierle, M Vendruscolo, G Veglia, CM Dobson, A De Simone
Nature communications
(2016)
7
(doi: 10.1038/ncomms12563)
Kinetics of fragmentation and dissociation of two-strand protein filaments: Coarse-grained simulations and experiments
A Zaccone, I Terentjev, TW Herling, TPJ Knowles, A Aleksandrova, EM Terentjev
(2016)
(doi: 10.48550/arxiv.1609.05027)
Kinetics of fragmentation and dissociation of two-strand protein filaments: Coarse-grained simulations and experiments.
A Zaccone, I Terentjev, TW Herling, TPJ Knowles, A Aleksandrova, EM Terentjev
J Chem Phys
(2016)
145
(doi: 10.1063/1.4962366)
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases.
E Evangelisti, R Cascella, M Becatti, G Marrazza, CM Dobson, F Chiti, M Stefani, C Cecchi
Sci Rep
(2016)
6
(doi: 10.1038/srep32721)
Unveiling (−)‐Englerin A as a Modulator of L‐Type Calcium Channels
T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes
Angewandte Chemie
(2016)
128
(doi: 10.1002/ange.201604336)
Physical determinants of the self-replication of protein fibrils.
A Šarić, AK Buell, G Meisl, TCT Michaels, CM Dobson, S Linse, TPJ Knowles, D Frenkel
Nat Phys
(2016)
12
(doi: 10.1038/nphys3828)
Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation
P Flagmeier, G Meisl, M Vendruscolo, TPJ Knowles, CM Dobson, AK Buell, C Galvagnion
Proceedings of the National Academy of Sciences of the United States of America
(2016)
113
(doi: 10.1073/pnas.1604645113)
Metadynamic metainference: Enhanced sampling of the metainference ensemble using metadynamics.
M Bonomi, C Camilloni, M Vendruscolo
Scientific reports
(2016)
6
(doi: 10.1038/srep31232)
Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells
A Drews, J Flint, N Shivji, P Jönsson, D Wirthensohn, E De Genst, C Vincke, S Muyldermans, C Dobson, D Klenerman
Scientific Reports
(2016)
6
(doi: 10.1038/srep31910)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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