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  • Currently displaying 1201 - 1220 of 2396 publications
Author(s)
Publication title
Journal Name
Publication year
Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity
EV Yates, T Müller, L Rajah, EJ De Genst, P Arosio, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
Nat Chem
(2015)
7
Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the α‐synuclein‐elicited immune response
A Labrador-Garrido, M Cejudo-Guillén, S Daturpalli, MM Leal, R Klippstein, EJ De Genst, J Villadiego, JJ Toledo-Aral, CM Dobson, SE Jackson, D Pozo, C Roodveldt
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
(2015)
30
Conformational effects of the A21G Flemish mutation on the aggregation of amyloid β peptide
M Yagi-Utsumi, CM Dobson
Biological and Pharmaceutical Bulletin
(2015)
38
Druggability of intrinsically disordered proteins
P Joshi, M Vendruscolo
Advances in experimental medicine and biology
(2015)
870
Structure and Dynamics of Intrinsically Disordered Proteins
B Fu, M Vendruscolo
Adv Exp Med Biol
(2015)
870
Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies
M Pickhardt, EM Mandelkow, E Mandelkow
Current medicinal chemistry
(2015)
12
Targeting disordered proteins with small molecules using entropy
GT Heller, P Sormanni, M Vendruscolo
Trends in biochemical sciences
(2015)
40
Oligomers of heat-shock proteins: Structures that don't imply function
WM Jacobs, TPJ Knowles, D Frenkel
(2015)
An N-Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species.
JD Seixas, M Chaves-Ferreira, D Montes-Grajales, AM Gonçalves, AR Marques, LM Saraiva, J Olivero-Verbel, CC Romão, GJL Bernardes
Chemistry
(2015)
21
Chromatin unfolding by epigenetic modifications explained by dramatic impairment of internucleosome interactions: A multiscale computational study
R Collepardo-Guevara, G Portella, M Vendruscolo, D Frenkel, T Schlick, M Orozco
Journal of the American Chemical Society
(2015)
137
Alzheimer’s disease: addressing a twenty-first century plague
CM Dobson
Rendiconti Lincei. Scienze Fisiche e Naturali
(2015)
26
Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α‑Synuclein Oligomers
MH Horrocks, L Tosatto, AJ Dear, GA Garcia, M Iljina, N Cremades, M Dalla Serra, TPJ Knowles, CM Dobson, D Klenerman
Anal Chem
(2015)
87
Peptide Anchor for Folate-Targeted Liposomal Delivery.
E Nogueira, IC Mangialavori, A Loureiro, NG Azoia, MP Sárria, P Nogueira, J Freitas, J Härmark, U Shimanovich, A Rollett, G Lacroix, GJL Bernardes, G Guebitz, H Hebert, A Moreira, AM Carmo, JPFC Rossi, AC Gomes, A Preto, A Cavaco-Paulo
Biomacromolecules
(2015)
16
A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate.
FA Aprile, P Sormanni, M Vendruscolo
Biochemistry
(2015)
54
Force generation by the growth of amyloid aggregates.
TW Herling, GA Garcia, TCT Michaels, W Grentz, J Dean, U Shimanovich, H Gang, T Müller, B Kav, EM Terentjev, CM Dobson, TPJ Knowles
Proceedings of the National Academy of Sciences
(2015)
112
Dynamics of protein aggregation and oligomer formation governed by secondary nucleation
TCT Michaels, HW Lazell, P Arosio, TPJ Knowles
The Journal of Chemical Physics
(2015)
143
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody
N Martínez-Sáez, J Castro-Lõpez, J Valero-González, D Madariaga, I Compañõn, VJ Somovilla, M Salvadõ, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJL Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana
Angewandte Chemie International Edition
(2015)
54
Molecular Rotors Provide Insights into Microscopic Structural Changes During Protein Aggregation
AJ Thompson, TW Herling, M Kubánková, A Vyšniauskas, TPJ Knowles, MK Kuimova
J Phys Chem B
(2015)
119
Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins.
P Sormanni, FA Aprile, M Vendruscolo
Proceedings of the National Academy of Sciences
(2015)
112
Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy
Y Pustovalova, P Kukic, M Vendruscolo, DM Korzhnev
Biochemistry
(2015)
54