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  • Currently displaying 1201 - 1220 of 2455 publications
Author(s)
Publication title
Journal Name
Publication year
Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the α-synuclein-elicited immune response
A Labrador-Garrido, M Cejudo-Guillén, S Daturpalli, MM Leal, R Klippstein, EJ De Genst, J Villadiego, JJ Toledo-Aral, CM Dobson, SE Jackson, D Pozo, C Roodveldt
FASEB Journal
(2015)
30
Conformational Effects of the A21G Flemish Mutation on the Aggregation of Amyloid β Peptide
M Yagi-Utsumi, CM Dobson
Biological and Pharmaceutical Bulletin
(2015)
38
Druggability of Intrinsically Disordered Proteins.
P Joshi, M Vendruscolo
Advances in experimental medicine and biology
(2015)
870
Structure and dynamics of intrinsically disordered proteins
B Fu, M Vendruscolo
Advances in Experimental Medicine and Biology
(2015)
870
Targeting disordered proteins with small molecules using entropy.
GT Heller, P Sormanni, M Vendruscolo
Trends in biochemical sciences
(2015)
40
Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies
M Pickhardt, EM Mandelkow, E Mandelkow
Current medicinal chemistry
(2015)
12
Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies
M Pickhardt, T Neumann, D Schwizer, K Callaway, M Vendruscolo, D Schenk, P St George-Hyslop, EM Mandelkow, CM Dobson, L McConlogue, E Mandelkow, G Tóth
Current Alzheimer research
(2015)
12
Oligomers of heat-shock proteins: Structures that don't imply function
WM Jacobs, TPJ Knowles, D Frenkel
(2015)
An N-Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species
JD Seixas, M Chaves-Ferreira, D Montes-Grajales, AM Gonçalves, AR Marques, LM Saraiva, J Olivero-Verbel, CC Romão, GJL Bernardes
Chemistry – A European Journal
(2015)
21
Chromatin unfolding by epigenetic modifications explained by dramatic impairment of internucleosome interactions: A multiscale computational study
R Collepardo-Guevara, G Portella, M Vendruscolo, D Frenkel, T Schlick, M Orozco
J Am Chem Soc
(2015)
137
Alzheimer's disease: addressing a twenty-first century plague
CM Dobson
Rendiconti Lincei
(2015)
26
Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α‑Synuclein Oligomers
MH Horrocks, L Tosatto, AJ Dear, GA Garcia, M Iljina, N Cremades, M Dalla Serra, TPJ Knowles, CM Dobson, D Klenerman
Analytical chemistry
(2015)
87
Peptide Anchor for Folate-Targeted Liposomal Delivery
E Nogueira, IC Mangialavori, A Loureiro, NG Azoia, MP Sárria, P Nogueira, J Freitas, J Härmark, U Shimanovich, A Rollett, G Lacroix, GJL Bernardes, G Guebitz, H Hebert, A Moreira, AM Carmo, JPFC Rossi, AC Gomes, A Preto, A Cavaco-Paulo
Biomacromolecules
(2015)
16
A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate
FA Aprile, P Sormanni, M Vendruscolo
Biochemistry
(2015)
54
Dynamics of protein aggregation and oligomer formation governed by secondary nucleation
TCT Michaels, HW Lazell, P Arosio, TPJ Knowles
Journal of Chemical Physics
(2015)
143
Force generation by the growth of amyloid aggregates
TW Herling, GA Garcia, TCT Michaels, W Grentz, J Dean, U Shimanovich, H Gang, T Müller, B Kav, EM Terentjev, CM Dobson, TPJ Knowles
Proceedings of the National Academy of Sciences
(2015)
112
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody
N Martínez-Sáez, J Castro-Lõpez, J Valero-González, D Madariaga, I Compañõn, VJ Somovilla, M Salvadõ, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJL Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana
Angewandte Chemie International Edition
(2015)
54
Molecular Rotors Provide Insights into Microscopic Structural Changes during Protein Aggregation
AJ Thompson, TW Herling, M Kubánková, A Vyšniauskas, TPJ Knowles, MK Kuimova
The journal of physical chemistry. B
(2015)
119
Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins.
P Sormanni, FA Aprile, M Vendruscolo
Proc Natl Acad Sci U S A
(2015)
112
Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy
Y Pustovalova, P Kukic, M Vendruscolo, DM Korzhnev
Biochemistry
(2015)
54