Centre for Misfolding Diseases

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  • Currently displaying 1081 - 1100 of 2508 publications
Author(s)
Publication title
Journal Name
Publication year
A Thioether-directed Palladium-cleavable Linker for Targeted Bioorthogonal Drug Decaging
BJ Stenton, BL Oliveira, MJ Matos, L Sinatra, GJL Bernardes
Chemical Science
(2018)
9
(doi: 10.1039/c8sc00256h)
Secondary nucleation in amyloid formation
M Törnquist, TCT Michaels, K Sanagavarapu, X Yang, G Meisl, SIA Cohen, TPJ Knowles, S Linse
Chemical communications (Cambridge, England)
(2018)
54
(doi: 10.1039/c8cc02204f)
Third generation antibody discovery methods: in silico rational design.
P Sormanni, FA Aprile, M Vendruscolo
Chem Soc Rev
(2018)
47
(doi: 10.1039/c8cs00523k)
A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism.
VE Zwicker, BL Oliveira, JH Yeo, ST Fraser, GJL Bernardes, EJ New, KA Jolliffe
Angewandte Chemie International Edition
(2018)
58
(doi: 10.1002/anie.201812489)
Observation of molecular self-assembly events in massively parallel microdroplet arrays
Z Toprakcioglu, PK Challa, A Levin, TPJ Knowles
Lab on A Chip
(2018)
18
(doi: 10.1039/c8lc00862k)
Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils.
JWP Brown, G Meisl, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion
Chem Commun (Camb)
(2018)
54
(doi: 10.1039/c8cc03002b)
Enhancing power density of biophotovoltaics by decoupling storage and power delivery
KL Saar, P Bombelli, DJ Lea-Smith, T Call, E-M Aro, T Müller, CJ Howe, TPJ Knowles
Nature Energy
(2018)
3
(doi: 10.1038/s41560-017-0073-0)
Glaucoma as a protein misfolding disease: an investigation of its metastable proteome
P Joshi, M Vendruscolo
JOURNAL OF ALZHEIMERS DISEASE
(2018)
64
Development of Antibody-Directed Therapies: Quo Vadis?
T Rodrigues, GJL Bernardes
Angewandte Chemie International Edition
(2018)
57
(doi: 10.1002/anie.201712185)
On-chip measurements of protein unfolding from direct observations of micron-scale diffusion
Y Zhang, EV Yates, L Hong, KL Saar, G Meisl, CM Dobson, TPJ Knowles
Chemical science
(2018)
9
(doi: 10.1039/c7sc04331g)
Microfluidic approaches for probing amyloid assembly and behaviour
TW Herling, A Levin, KL Saar, CM Dobson, TPJ Knowles
Lab Chip
(2018)
18
(doi: 10.1039/c7lc01241a)
A silicon‐labelled amino acid suitable for late‐stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis
KR Scroggie, LJ Alcock, MJ Matos, GJL Bernardes, MV Perkins, JM Chalker
Peptide Science
(2018)
110
(doi: 10.1002/pep2.24069)
Microfluidics for Protein Biophysics.
J Charmet, P Arosio, TPJ Knowles
J Mol Biol
(2017)
430
(doi: 10.1016/j.jmb.2017.12.015)
The use of fluoroproline in MUC1 antigen enables efficient detection of antibodies in patients with prostate cancer
VJ Somovilla, IA Bermejo, IS Albuquerque, N Martínez-Sáez, J Castro-López, F García-Martín, I Compañón, H Hinou, S Nishimura, J Jiménez-Barbero, JL Asensio, A Avenoza, JH Busto,, R Hurtado-Guerrero, JM Peregrina, GJ Lopes Bernardes, F Corzana1
J Am Chem Soc
(2017)
139
(doi: 10.1021/jacs.7b09447)
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers.
G Fusco, SW Chen, PTF Williamson, R Cascella, M Perni, JA Jarvis, C Cecchi, M Vendruscolo, F Chiti, N Cremades, L Ying, CM Dobson, A De Simone
Science (New York, N.Y.)
(2017)
358
(doi: 10.1126/science.aan6160)
Chemoselective Installation of Amine Bonds on Proteins Through Aza-Michael Ligation
AM Freedy, MJ Matos, O Boutureira, F Corzana, A Guerreiro, P Akkapeddi, VJ Somovilla, T Rodrigues, K Nicholls, B Xie, G Jiménez-Osés, KM Brindle, AA Neves, GJL Bernardes
J Am Chem Soc
(2017)
139
(doi: 10.1021/jacs.7b10702)
Inhibiting the Ca
A Drews, S De, P Flagmeier, DC Wirthensohn, W-H Chen, DR Whiten, M Rodrigues, C Vincke, S Muyldermans, RW Paterson, CF Slattery, NC Fox, JM Schott, H Zetterberg, CM Dobson, S Gandhi, D Klenerman
Cell Reports
(2017)
21
(doi: 10.1016/j.celrep.2017.11.057)
Precise Probing of Residue Roles by Post-Translational β,γ-C,N Aza-Michael Mutagenesis in Enzyme Active Sites.
J Dadová, K-J Wu, PG Isenegger, JC Errey, GJL Bernardes, JM Chalker, L Raich, C Rovira, BG Davis
ACS Central Science
(2017)
3
(doi: 10.1021/acscentsci.7b00341)
Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
N Martínez-Sáez, S Sun, D Oldrini, P Sormanni, O Boutureira, F Carboni, I Compañón, MJ Deery, M Vendruscolo, F Corzana, R Adamo, GJ Lopes Bernardes
Angew Chem Int Ed Engl
(2017)
56
(doi: 10.1002/anie.201708847)
Oxetane Grafts Installed Site-Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
N Martínez‐Sáez, S Sun, D Oldrini, P Sormanni, O Boutureira, F Carboni, I Compañón, MJ Deery, M Vendruscolo, F Corzana, R Adamo, GJL Bernardes
Angewandte Chemie
(2017)
129
(doi: 10.1002/ange.201708847)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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