Centre for Misfolding Diseases

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  • Currently displaying 1081 - 1100 of 2401 publications
Author(s)
Publication title
Journal Name
Publication year
On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products.
KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, X Yang, S Linse, TPJ Knowles
Lab on a chip
(2017)
18
(doi: 10.1039/c7lc00797c)
Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning.
PK Challa, T Kartanas, J Charmet, TPJ Knowles
Biomicrofluidics
(2017)
11
(doi: 10.1063/1.4976690)
Measuring the prion-like character of tau by TIRF microscopy
F Kundel, B Falcon, L Hong, N Esteras, AJ Dear, AY Abramov, TPJ Knowles, M Goedert, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils
M Tornquist, R Cukalevski, U Weininger, G Meisl, TPJ Knowles, T Leiding, M Akke, S Linse
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Ultrasensitive measurement of Ca2+ influx into lipid vesicles induced by protein aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TP Knowles, S Gandhi, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Single α-synuclein oligomers are hydrophobically distinct from mature fibrils
J-E Lee, MN Bongiovanni, M Rodrigues, CM Dobson, SF Lee, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease
J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences
(2016)
114
(doi: 10.1073/pnas.1615613114)
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping.
MN Bongiovanni, J Godet, MH Horrocks, L Tosatto, AR Carr, DC Wirthensohn, RT Ranasinghe, JV Fritz, CM Dobson, D Klenerman, SF Lee
Nat Commun
(2016)
7
(doi: 10.1038/ncomms13544)
Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
The Journal of Chemical Physics
(2016)
145
(doi: 10.1063/1.4965040)
The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme
M Ahn, CL Hagan, A Bernardo-Gancedo, E De Genst, FN Newby, J Christodoulou, A Dhulesia, M Dumoulin, CV Robinson, CM Dobson, JR Kumita
Biophys J
(2016)
111
(doi: 10.1016/j.bpj.2016.10.028)
Micro- and nanoscale hierarchical structure of core–shell protein microgels
LR Volpatti, U Shimanovich, FS Ruggeri, S Bolisetty, T Müller, TO Mason, TCT Michaels, R Mezzenga, G Dietler, TPJ Knowles
Journal of Materials Chemistry B
(2016)
4
(doi: 10.1039/c6tb02683d)
Trends in therapeutic drug conjugates for bacterial diseases: a patent review
PMSD Cal, MJ Matos, GJL Bernardes
Expert Opinion on Therapeutic Patents
(2016)
27
(doi: 10.1080/13543776.2017.1259411)
The missing link
T Rodrigues, GJL Bernardes
Nature chemistry
(2016)
8
(doi: 10.1038/nchem.2685)
A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels–Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez-Osés, GJL Bernardes
Angewandte Chemie - International Edition
(2016)
55
(doi: 10.1002/anie.201608438)
A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez‐Osés, GJL Bernardes
Angewandte Chemie
(2016)
128
(doi: 10.1002/ange.201608438)
Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ.
DC Butler, SN Joshi, ED Genst, AS Baghel, CM Dobson, A Messer
PloS one
(2016)
11
(doi: 10.1371/journal.pone.0165964)
Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents.
T Rodrigues, F Sieglitz, GJL Bernardes
Chemical Society Reviews
(2016)
45
(doi: 10.1039/c5cs00916b)
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, WL Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, ML Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis
Science (New York, N.Y.)
(2016)
354
Dynamics of heteromolecular filament formation
AJ Dear, TCT Michaels, TPJ Knowles
The Journal of Chemical Physics
(2016)
145
(doi: 10.1063/1.4966571)
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces.
JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, M Vendruscolo, TPJ Knowles, CM Dobson, C Galvagnion
Scientific Reports
(2016)
6
(doi: 10.1038/srep36010)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
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