Centre for Misfolding Diseases

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  • Currently displaying 1081 - 1100 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Oxidative Activation of C-S Bonds with an Electropositive Nitrogen Promoter Enables Orthogonal Glycosylation of Alkyl over Phenyl Thioglycosides
A Kitowski, E Jiménez-Moreno, M Salvadó, J Mestre, S Castillón, G Jiménez-Osés, O Boutureira, GJL Bernardes
Organic letters
(2017)
19
(doi: 10.1021/acs.orglett.7b02886)
Mechanisms of Amyloid-β 42 oligomer formation from kinetic analysis
TC Michaels, A Saric, HW Lazell, P Arosio, M Vendruscolo, CM Dobson, S Linse, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Norbornene probes for the study of cysteine oxidation
LJ Alcock, KD Farrell, MT Akol, GH Jones, MM Tierney, HB Kramer, TL Pukala, GJL Bernardes, MV Perkins, JM Chalker
Tetrahedron
(2017)
74
(doi: 10.1016/j.tet.2017.11.011)
Measuring the prion-like character of tau by TIRF microscopy
F Kundel, B Falcon, L Hong, N Esteras, AJ Dear, AY Abramov, TPJ Knowles, M Goedert, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils
M Tornquist, R Cukalevski, U Weininger, G Meisl, TPJ Knowles, T Leiding, M Akke, S Linse
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Ultrasensitive measurement of Ca2+ influx into lipid vesicles induced by protein aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TP Knowles, S Gandhi, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products.
KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, X Yang, S Linse, TPJ Knowles
Lab Chip
(2017)
18
(doi: 10.1039/c7lc00797c)
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease
J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2016)
114
(doi: 10.1073/pnas.1615613114)
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping
MN Bongiovanni, J Godet, MH Horrocks, L Tosatto, AR Carr, DC Wirthensohn, RT Ranasinghe, JV Fritz, CM Dobson, D Klenerman, SF Lee
Nat Commun
(2016)
7
(doi: 10.1038/ncomms13544)
Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation.
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
The Journal of chemical physics
(2016)
145
(doi: 10.1063/1.4965040)
The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme
M Ahn, CL Hagan, A Bernardo-Gancedo, E De Genst, FN Newby, J Christodoulou, A Dhulesia, M Dumoulin, CV Robinson, CM Dobson, JR Kumita
Biophys J
(2016)
111
(doi: 10.1016/j.bpj.2016.10.028)
Micro- and nanoscale hierarchical structure of core-shell protein microgels.
LR Volpatti, U Shimanovich, FS Ruggeri, S Bolisetty, T Müller, TO Mason, TCT Michaels, R Mezzenga, G Dietler, TPJ Knowles
Journal of Materials Chemistry B
(2016)
4
(doi: 10.1039/c6tb02683d)
Trends in therapeutic drug conjugates for bacterial diseases: a patent review.
PMSD Cal, MJ Matos, GJL Bernardes
Expert Opin Ther Pat
(2016)
27
(doi: 10.1080/13543776.2017.1259411)
Antibody-drug conjugates: The missing link.
T Rodrigues, GJL Bernardes
Nature Chemistry
(2016)
8
(doi: 10.1038/nchem.2685)
A Minimal, Unstrained S‐Allyl Handle for Pre‐Targeting Diels–Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez‐Osés, GJL Bernardes
Angewandte Chemie
(2016)
128
(doi: 10.1002/ange.201608438)
A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez-Osés, GJL Bernardes
Angewandte Chemie (International ed. in English)
(2016)
55
(doi: 10.1002/anie.201608438)
Bifunctional anti-non-amyloid component α-Synuclein nanobodies are protective in situ
DC Butler, SN Joshi, ED Genst, AS Baghel, CM Dobson, A Messer
Plos One
(2016)
11
(doi: 10.1371/journal.pone.0165964)
Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents
T Rodrigues, F Sieglitz, GJL Bernardes
Chem Soc Rev
(2016)
45
(doi: 10.1039/c5cs00916b)
Dynamics of heteromolecular filament formation
AJ Dear, TCT Michaels, TPJ Knowles
Journal of Chemical Physics
(2016)
145
(doi: 10.1063/1.4966571)
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, WL Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, ML Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis
Science (New York, N.Y.)
(2016)
354
Yusuf Hamied Department of Chemistry
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