Centre for Misfolding Diseases

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  • Currently displaying 1081 - 1100 of 2455 publications
Author(s)
Publication title
Journal Name
Publication year
Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning
PK Challa, T Kartanas, J Charmet, TPJ Knowles
Biomicrofluidics
(2017)
11
(doi: 10.1063/1.4976690)
Structural characterisation of the early events in the nucleation-condensation mechanism of folding
P Kukic, Y Pustovalova, C Camilloni, S Gianni, DM Korzhnev, M Vendruscolo
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease.
J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2016)
114
(doi: 10.1073/pnas.1615613114)
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping.
MN Bongiovanni, J Godet, MH Horrocks, L Tosatto, AR Carr, DC Wirthensohn, RT Ranasinghe, JV Fritz, CM Dobson, D Klenerman, SF Lee
Nature communications
(2016)
7
(doi: 10.1038/ncomms13544)
Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
The Journal of Chemical Physics
(2016)
145
(doi: 10.1063/1.4965040)
The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme.
M Ahn, CL Hagan, A Bernardo-Gancedo, E De Genst, FN Newby, J Christodoulou, A Dhulesia, M Dumoulin, CV Robinson, CM Dobson, JR Kumita
Biophys J
(2016)
111
(doi: 10.1016/j.bpj.2016.10.028)
Micro- and nanoscale hierarchical structure of core-shell protein microgels
LR Volpatti, U Shimanovich, FS Ruggeri, S Bolisetty, T Müller, TO Mason, TCT Michaels, R Mezzenga, G Dietler, TPJ Knowles
Journal of Materials Chemistry B
(2016)
4
(doi: 10.1039/c6tb02683d)
Trends in therapeutic drug conjugates for bacterial diseases: a patent review.
PMSD Cal, MJ Matos, GJL Bernardes
Expert opinion on therapeutic patents
(2016)
27
(doi: 10.1080/13543776.2017.1259411)
Antibody-drug conjugates: The missing link
T Rodrigues, GJL Bernardes
Nature chemistry
(2016)
8
(doi: 10.1038/nchem.2685)
A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez‐Osés, GJL Bernardes
Angewandte Chemie
(2016)
128
(doi: 10.1002/ange.201608438)
A Minimal, Unstrained S‐Allyl Handle for Pre‐Targeting Diels–Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez-Osés, GJL Bernardes
Angewandte Chemie International Edition
(2016)
55
(doi: 10.1002/anie.201608438)
Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ
DC Butler, SN Joshi, ED Genst, AS Baghel, CM Dobson, A Messer
PloS one
(2016)
11
(doi: 10.1371/journal.pone.0165964)
Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents.
T Rodrigues, F Sieglitz, GJL Bernardes
Chemical Society reviews
(2016)
45
(doi: 10.1039/c5cs00916b)
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, WL Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, ML Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis
Science (New York, N.Y.)
(2016)
354
Dynamics of heteromolecular filament formation.
AJ Dear, TCT Michaels, TPJ Knowles
J Chem Phys
(2016)
145
(doi: 10.1063/1.4966571)
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces.
JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, M Vendruscolo, TPJ Knowles, CM Dobson, C Galvagnion
Scientific Reports
(2016)
6
(doi: 10.1038/srep36010)
Chapter Three Structural Characteristics of α-Synuclein Oligomers
N Cremades, SW Chen, CM Dobson
Int Rev Cell Mol Biol
(2016)
329
(doi: 10.1016/bs.ircmb.2016.08.010)
Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents.
B Bernardim, PMSD Cal, MJ Matos, BL Oliveira, N Martínez-Sáez, IS Albuquerque, E Perkins, F Corzana, ACB Burtoloso, G Jiménez-Osés, GJL Bernardes
Nature Communications
(2016)
7
(doi: 10.1038/ncomms13128)
Dynamic microfluidic control of supramolecular peptide self-assembly.
ZA Arnon, A Vitalis, A Levin, TCT Michaels, A Caflisch, TPJ Knowles, L Adler-Abramovich, E Gazit
Nature communications
(2016)
7
(doi: 10.1038/ncomms13190)
Scaling and dimensionality in the chemical kinetics of protein filament formation
TCT Michaels, AJ Dear, TPJ Knowles
International Reviews in Physical Chemistry
(2016)
35
(doi: 10.1080/0144235x.2016.1239335)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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