Centre for Misfolding Diseases

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  • Currently displaying 1541 - 1560 of 2474 publications
Author(s)
Publication title
Journal Name
Publication year
A novel carbon monoxide-releasing molecule fully protects mice from severe malaria.
AC Pena, N Penacho, L Mancio-Silva, R Neres, JD Seixas, AC Fernandes, CC Romão, MM Mota, GJL Bernardes, A Pamplona
Antimicrob Agents Chemother
(2012)
56
(doi: 10.1128/AAC.05571-11)
The aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila.
JM Gregory, TP Barros, S Meehan, CM Dobson, LM Luheshi
PLoS ONE
(2012)
7
(doi: 10.1371/journal.pone.0031899)
Characterization of the conformational equilibrium between the two major substates of RNase a using NMR chemical shifts
C Camilloni, P Robustelli, A De Simone, A Cavalli, M Vendruscolo
Journal of the American Chemical Society
(2012)
134
(doi: 10.1021/ja210951z)
Developing drug molecules for therapy with carbon monoxide.
CC Romão, WA Blättler, JD Seixas, GJL Bernardes
Chemical Society reviews
(2012)
41
(doi: 10.1039/c2cs15317c)
Blind testing of routine, fully automated determination of protein structures from nmr data
A Rosato, JM Aramini, C Arrowsmith, A Bagaria, D Baker, A Cavalli, JF Doreleijers, A Eletsky, A Giachetti, P Guerry, A Gutmanas, P Güntert, Y He, T Herrmann, YJ Huang, V Jaravine, HRA Jonker, MA Kennedy, OF Lange, G Liu, TE Malliavin, R Mani, B Mao, GT Montelione, M Nilges, P Rossi, G Van Der Schot, H Schwalbe, TA Szyperski, M Vendruscolo, R Vernon, WF Vranken, S De Vries, GW Vuister, B Wu, Y Yang, AMJJ Bonvin
Structure
(2012)
20
(doi: 10.1016/j.str.2012.01.002)
Investigating the Factors Affecting the Aggregation of Alpha-Synuclein using Single Molecule Fluorescence and Fast Flow Microfluidics
MH Horrocks, N Cremades, L Tosatto, T Guilliams, E De Genst, J-U Shim, CM Dobson, D Klenerman
Biophysical Journal
(2012)
102
(doi: 10.1016/j.bpj.2011.11.1407)
Mechanism of Non-Specific Inhibitors of Amyloid Assembly: Interactions of Lacmoid with the Amyloid Beta Peptide
A Abelein, B Bolognesi, CM Dobson, A Gräslund, C Lendel
Biophysical Journal
(2012)
102
(doi: 10.1016/j.bpj.2011.11.2417)
Measuring the Kinetics of Amyloid Fibril Elongation Using Quartz Crystal Microbalances
AK Buell, CM Dobson, ME Welland
Methods in molecular biology (Clifton, N.J.)
(2012)
849
(doi: 10.1007/978-1-61779-551-0_8)
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers
E Evangelisti, C Cecchi, R Cascella, C Sgromo, M Becatti, CM Dobson, F Chiti, M Stefani
Journal of Cell Science
(2012)
125
(doi: 10.1242/jcs.098434)
Protein structure validation using side-chain chemical shifts.
AB Sahakyan, A Cavalli, WF Vranken, M Vendruscolo
The Journal of Physical Chemistry B
(2012)
116
(doi: 10.1021/jp2122054)
Anti-oligomer monoclonal antibodies reveal that protein aggregation modulates generalized physiological and pathological disturbances
M Tayebi, M Vendruscolo, M David
PRION
(2012)
6
The nature and significance of protein aggregation phenomena
CM Dobson
PRION
(2012)
6
Nanobodies as structural probes of protein misfolding and fibril formation
E De Genst, CM Dobson
Methods in Molecular Biology
(2012)
911
(doi: 10.1007/978-1-61779-968-6_34)
Selenenylsulfide-Linked Homogeneous Glycopeptides and Glycoproteins: Synthesis of Human "Hepatic Se Metabolite A"
O Boutureira, GJL Bernardes, M Fernández-González, DC Anthony, BG Davis
Angew Chem Int Ed Engl
(2011)
51
(doi: 10.1002/anie.201106658)
A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy
GJL Bernardes, G Casi, S Trüssel, I Hartmann, K Schwager, J Scheuermann, D Neri
Angew. Chem. Int. Ed.
(2011)
51
(doi: 10.1002/anie.201106527)
Hydrophobicity and Conformational Change as Mechanistic Determinants for Nonspecific Modulators of Amyloid beta Self-Assembly
A Abelein, B Bolognesi, CM Dobson, A Gräslund, C Lendel
Biochemistry
(2011)
51
(doi: 10.1021/bi201745g)
Experimental free energy surfaces reveal the mechanisms of maintenance of protein solubility
A De Simone, A Dhulesia, G Soldi, M Vendruscolo, S-TD Hsu, F Chiti, CM Dobson
Proc Natl Acad Sci U S A
(2011)
108
(doi: 10.1073/pnas.1112197108)
Protein solubility and protein homeostasis: A generic view of protein misfolding disorders
M Vendruscolo, TPJ Knowles, CM Dobson
Cold Spring Harbor Perspectives in Biology
(2011)
3
(doi: 10.1101/cshperspect.a010454)
Clusterin facilitates in vivo clearance of extracellular misfolded proteins
AR Wyatt, JJ Yerbury, P Berghofer, I Greguric, A Katsifis, CM Dobson, MR Wilson
Cellular and Molecular Life Sciences
(2011)
68
(doi: 10.1007/s00018-011-0684-8)
Determination of Conformational Equilibria in Proteins Using Residual Dipolar Couplings.
A De Simone, RW Montalvao, M Vendruscolo
Journal of chemical theory and computation
(2011)
7
(doi: 10.1021/ct200361b)
Yusuf Hamied Department of Chemistry
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