Centre for Misfolding Diseases

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  • Currently displaying 1541 - 1560 of 2523 publications
Author(s)
Publication title
Journal Name
Publication year
In Vivo Translation Rates Can Substantially Delay the Co-Translational Folding of the E. Coli Cytosolic Proteome
P Ciryam, RI Morimoto, M Vendruscolo, CM Dobson, EP O'Brien
Biophysical Journal
(2013)
104
(doi: 10.1016/j.bpj.2012.11.3207)
Sequence-Based Prediction of Protein Behavior
GG Tartaglia, M Vendruscolo
(2013)
(doi: 10.1002/9783527654185.ch9)
The Amyloid Phenomenon and Its Significance
CM Dobson
(2013)
(doi: 10.1002/9783527654185.ch1)
The Kinetics and Mechanisms of Amyloid Formation
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
(2013)
(doi: 10.1002/9783527654185.ch10)
Single Molecule Characterization of the Interactions between Amyloid‑β Peptides and the Membranes of Hippocampal Cells
P Narayan, KA Ganzinger, J McColl, L Weimann, S Meehan, S Qamar, JA Carver, MR Wilson, P St George-Hyslop, CM Dobson, D Klenerman
Journal of the American Chemical Society
(2013)
135
(doi: 10.1021/ja3103567)
Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses.
M Yolamanova, C Meier, AK Shaytan, V Vas, CW Bertoncini, F Arnold, O Zirafi, SM Usmani, JA Müller, D Sauter, C Goffinet, D Palesch, P Walther, NR Roan, H Geiger, O Lunov, T Simmet, J Bohne, H Schrezenmeier, K Schwarz, L Ständker, W-G Forssmann, X Salvatella, PG Khalatur, AR Khokhlov, TPJ Knowles, T Weil, F Kirchhoff, J Münch
Nature Nanotechnology
(2013)
8
(doi: 10.1038/nnano.2012.248)
Spacer length shapes drug release and therapeutic efficacy of traceless disulfide-linked ADCs targeting the tumor neovasculature
M Steiner, I Hartmann, E Perrino, G Casi, S Brighton, I Jelesarov, GJL Bernardes, D Neri
Chemical Science
(2013)
4
(doi: 10.1039/c2sc21107f)
Structure of a Misfolded Intermediate of a PDZ Domain
A De Simone, S Gianni, M Vendruscolo
Bio-nanoimaging: Protein Misfolding and Aggregation
(2013)
(doi: 10.1016/B978-0-12-394431-3.00041-9)
New approaches to understanding and preventing neurodegenerative diseases
CM Dobson
PRION
(2013)
7
In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome
P Ciryam, RI Morimoto, M Vendruscolo, CM Dobson, EP O'Brien
Proc Natl Acad Sci U S A
(2012)
110
(doi: 10.1073/pnas.1213624110)
Preconditioning of microglia with Parkinson-linked alpha-synuclein affects the response induced by Toll-like receptor (TLR) stimulation
C Roodveldt, A Labrador-Garrido, E Gonzalez-Rey, CC Lachaud, T Guilliams, R Fernandez-Montesinos, A Hmadcha, M Delgado, CM Dobson, D Pozo
JOURNAL OF NEUROIMMUNOLOGY
(2012)
253
Analysis of the Native Structure, Stability and Aggregation of Biotinylated Human Lysozyme
M Ahn, E De Genst, GS Kaminski Schierle, M Erdelyi, CF Kaminski, CM Dobson, JR Kumita
Plos One
(2012)
7
(doi: 10.1371/journal.pone.0050192)
Amyloid-β Oligomers are Sequestered by both Intracellular and Extracellular Chaperones
P Narayan, S Meehan, JA Carver, MR Wilson, CM Dobson, D Klenerman
Biochemistry
(2012)
51
(doi: 10.1021/bi301277k)
A rationally designed six-residue swap generates comparability in the aggregation behavior of α-synuclein and β-synuclein.
C Roodveldt, A Andersson, EJ De Genst, A Labrador-Garrido, AK Buell, CM Dobson, GG Tartaglia, M Vendruscolo
Biochemistry
(2012)
51
(doi: 10.1021/bi300558q)
Connecting Macroscopic Observables and Microscopic Assembly Events in Amyloid Formation Using Coarse Grained Simulations
NS Bieler, TPJ Knowles, D Frenkel, R Vácha
PLOS Computational Biology
(2012)
8
(doi: 10.1371/journal.pcbi.1002692)
Twisting transition between crystalline and fibrillar phases of aggregated peptides
TPJ Knowles, A De Simone, AW Fitzpatrick, A Baldwin, S Meehan, L Rajah, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev
Physical review letters
(2012)
109
(doi: 10.1103/PhysRevLett.109.158101)
Highly non-linear microfluidic resistor elements for flow rate-dependent addressing of microchannels
L Rajah, DA White, TPJ Knowles
International Journal of Nonlinear Sciences and Numerical Simulation
(2012)
13
(doi: 10.1515/ijnsns-2012-0401)
In support of the BMRB
JL Markley, H Akutsu, T Asakura, M Baldus, R Boelens, A Bonvin, R Kaptein, A Bax, I Bezsonova, MR Gryk, JC Hoch, DM Korzhnev, MW Maciejewski, D Case, WJ Chazin, TA Cross, S Dames, H Kessler, O Lange, T Madl, B Reif, M Sattler, D Eliezer, A Fersht, J Forman-Kay, LE Kay, J Fraser, J Gross, T Kortemme, A Sali, T Fujiwara, K Gardner, X Luo, J Rizo-Rey, M Rosen, RR Gil, C Ho, G Rule, AM Gronenborn, R Ishima, J Klein-Seetharaman, P Tang, P van der Wel, Y Xu, S Grzesiek, S Hiller, J Seelig, ED Laue, H Mott, D Nietlispach, I Barsukov, L-Y Lian, D Middleton, T Blumenschein, G Moore, I Campbell, J Schnell, IJ Vakonakis, A Watts, MR Conte, J Mason, M Pfuhl, MR Sanderson, J Craven, M Williamson, C Dominguez, G Roberts, U Günther, M Overduin, J Werner, P Williamson, C Blindauer, M Crump, P Driscoll, T Frenkiel, A Golovanov, S Matthews, J Parkinson, D Uhrin, M Williams, D Neuhaus, H Oschkinat, A Ramos, DE Shaw, C Steinbeck, M Vendruscolo, GW Vuister, KJ Walters, H Weinstein, K Wüthrich, S Yokoyama
Nat Struct Mol Biol
(2012)
19
(doi: 10.1038/nsmb.2371)
NMR chemical shifts and protein dynamics
C Camilloni, M Vendruscolo
FEBS JOURNAL
(2012)
279
Co-translational folding of E. coli's cytosolic proteome exhibits kinetic effects that can significantly delay folding
P Ciryam, M Vendruscolo, CM Dobson, EP O'Brien
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
244
Yusuf Hamied Department of Chemistry
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