Centre for Misfolding Diseases

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  • Currently displaying 1461 - 1480 of 2455 publications
Author(s)
Publication title
Journal Name
Publication year
Determination of structural fluctuations of proteins from structure-based calculations of residual dipolar couplings
RW Montalvao, A De Simone, M Vendruscolo
Journal of Biomolecular NMR
(2012)
53
(doi: 10.1007/s10858-012-9644-3)
Trigger factor slows Co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant cytosolic interactions
EP O'Brien, J Christodoulou, M Vendruscolo, CM Dobson
J Am Chem Soc
(2012)
134
(doi: 10.1021/ja302305u)
Fucose-specific conjugation of hydrazide derivatives to a vascular-targeting monoclonal antibody in IgG format
K Zuberbühler, G Casi, GJL Bernardes, D Neri
Chemical communications (Cambridge, England)
(2012)
48
(doi: 10.1039/c2cc32412a)
Selenium-enhanced electron microscopic imaging of different aggregate forms of a segment of the amyloid β peptide in cells.
EK McGuire, M Motskin, B Bolognesi, SD Bergin, TPJ Knowles, J Skepper, LM Luheshi, DW McComb, CM Dobson, AE Porter
ACS Nano
(2012)
6
(doi: 10.1021/nn204859e)
Characterizing intermolecular interactions that initiate native-like protein aggregation
F Bemporad, A De Simone, F Chiti, CM Dobson
Biophysical Journal
(2012)
102
(doi: 10.1016/j.bpj.2012.03.057)
Prediction of variable translation rate effects on cotranslational protein folding
EP O'Brien, M Vendruscolo, CM Dobson
Nature Communications
(2012)
3
(doi: 10.1038/ncomms1850)
Direct observation of the interconversion of normal and toxic forms of α-synuclein.
N Cremades, SIA Cohen, E Deas, AY Abramov, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, NW Wood, TPJ Knowles, CM Dobson, D Klenerman
Cell
(2012)
149
(doi: 10.1016/j.cell.2012.03.037)
Role of Elongation and Secondary Pathways in S6 Amyloid Fibril Growth
N Lorenzen, SIA Cohen, SB Nielsen, TW Herling, G Christiansen, CM Dobson, TPJ Knowles, D Otzen
Biophys J
(2012)
102
(doi: 10.1016/j.bpj.2012.03.047)
Fibrillogenic propensity of the GroEL apical domain: A Janus-faced minichaperone
J Chen, H Yagi, P Sormanni, M Vendruscolo, K Makabe, T Nakamura, Y Goto, K Kuwajima
FEBS Letters
(2012)
586
(doi: 10.1016/j.febslet.2012.03.019)
Structure of an intermediate state in protein folding and aggregation
P Neudecker, P Robustelli, A Cavalli, P Walsh, P Lundström, A Zarrine-Afsar, S Sharpe, M Vendruscolo, LE Kay
Science (New York, N.Y.)
(2012)
336
(doi: 10.1126/science.1214203)
Intrinsic disorder modulates protein self-assembly and aggregation
A De Simone, C Kitchen, AH Kwan, M Sunde, CM Dobson, D Frenkel
Proceedings of the National Academy of Sciences of the United States of America
(2012)
109
(doi: 10.1073/pnas.1118048109)
Analyse der Energiebarrieren für das Wachstum von Amyloidfibrillen
AK Buell, A Dhulesia, DA White, TPJ Knowles, CM Dobson, ME Welland
Angewandte Chemie
(2012)
124
(doi: 10.1002/ange.201108040)
Detailed analysis of the energy barriers for amyloid fibril growth
AK Buell, A Dhulesia, DA White, TPJ Knowles, CM Dobson, ME Welland
Angew Chem Int Ed Engl
(2012)
51
(doi: 10.1002/anie.201108040)
1H, 13C and 15N resonance assignments of human muscle acylphosphatase
G Fusco, A De Simone, STD Hsu, F Bemporad, M Vendruscolo, F Chiti, CM Dobson
Biomolecular NMR Assignments
(2012)
6
(doi: 10.1007/s12104-011-9318-1)
Proteome folding and aggregation
M Vendruscolo
Current Opinion in Structural Biology
(2012)
22
(doi: 10.1016/j.sbi.2012.01.005)
Expression in Drosophila of Tandem Amyloid β Peptides Provides Insights into Links between Aggregation and Neurotoxicity*
E Speretta, TR Jahn, GG Tartaglia, G Favrin, TP Barros, S Imarisio, DA Lomas, LM Luheshi, DC Crowther, CM Dobson
Journal of Biological Chemistry
(2012)
287
(doi: 10.1074/jbc.m112.350124)
Fibrillogenic propensity of the GroEL apical domain: A Janus-faced minichaperone
J Chen, H Yagi, P Sormanni, M Vendruscolo, K Makabe, T Nakamura, Y Goto, K Kuwajima
FEBS Lett
(2012)
586
(doi: 10.1016/j.febslet.2012.03.019)
From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
J Mol Biol
(2012)
421
(doi: 10.1016/j.jmb.2012.02.031)
Determination of Secondary Structure Populations in Disordered States of Proteins Using Nuclear Magnetic Resonance Chemical Shifts
C Camilloni, A De Simone, WF Vranken, M Vendruscolo
Biochemistry
(2012)
51
(doi: 10.1021/bi3001825)
A novel carbon monoxide-releasing molecule fully protects mice from severe malaria
AC Pena, N Penacho, L Mancio-Silva, R Neres, JD Seixas, AC Fernandes, CC Romão, MM Mota, GJL Bernardes, A Pamplona
Antimicrobial Agents and Chemotherapy
(2012)
56
(doi: 10.1128/aac.05571-11)
Yusuf Hamied Department of Chemistry
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