Centre for Misfolding Diseases

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  • Currently displaying 1461 - 1480 of 2489 publications
Author(s)
Publication title
Journal Name
Publication year
Polymer physics inspired approaches for the study of the mechanical properties of amyloid fibrils
LR Volpatti, TPJ Knowles
Journal of Polymer Science Part B Polymer Physics
(2013)
52
(doi: 10.1002/polb.23428)
Replica-Averaged Metadynamics
C Camilloni, A Cavalli, M Vendruscolo
Journal of chemical theory and computation
(2013)
9
(doi: 10.1021/ct4006272)
Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation
C Roodveldt, A Labrador-Garrido, E Gonzalez-Rey, CC Lachaud, T Guilliams, R Fernandez-Montesinos, A Benitez-Rondan, G Robledo, A Hmadcha, M Delgado, CM Dobson, D Pozo
PloS one
(2013)
8
(doi: 10.1371/journal.pone.0079160)
Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins.
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo
Cell reports
(2013)
5
(doi: 10.1016/j.celrep.2013.09.043)
pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins.
M Varadi, S Kosol, P Lebrun, E Valentini, M Blackledge, AK Dunker, IC Felli, JD Forman-Kay, RW Kriwacki, R Pierattelli, J Sussman, DI Svergun, VN Uversky, M Vendruscolo, D Wishart, PE Wright, P Tompa
Nucleic acids research
(2013)
42
(doi: 10.1093/nar/gkt960)
Highlights from the 48th EUCHEM conference on stereochemistry, Burgenstock, Switzerland, May 2013
GJL Bernardes
Chem Commun (Camb)
(2013)
49
(doi: 10.1039/c3cc90259e)
Site-specific chemical modification of antibody fragments using traceless cleavable linkers
GJL Bernardes, M Steiner, I Hartmann, D Neri, G Casi
Nature Protocols
(2013)
8
(doi: 10.1038/nprot.2013.121)
Cucurbit[8]uril and Blue-Box: High-Energy Water Release Overwhelms Electrostatic Interactions
F Biedermann, M Vendruscolo, OA Scherman, A De Simone, WM Nau
J Am Chem Soc
(2013)
135
(doi: 10.1021/ja407951x)
A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
E De Genst, P-H Chan, E Pardon, S-TD Hsu, JR Kumita, J Christodoulou, L Menzer, DY Chirgadze, CV Robinson, S Muyldermans, A Matagne, L Wyns, CM Dobson, M Dumoulin
J Phys Chem B
(2013)
117
(doi: 10.1021/jp403425z)
Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase.
A Pica, A Merlino, AK Buell, TPJ Knowles, E Pizzo, G D'Alessio, F Sica, L Mazzarella
Acta Crystallogr D Biol Crystallogr
(2013)
69
(doi: 10.1107/S0907444913020507)
Subdomain architecture and stability of a giant repeat protein.
M Tsytlonok, P Sormanni, PJE Rowling, M Vendruscolo, LS Itzhaki
The journal of physical chemistry. B
(2013)
117
(doi: 10.1021/jp402360x)
Structures of the excited states of phospholamban and shifts in their populations upon phosphorylation.
A De Simone, M Gustavsson, RW Montalvao, L Shi, G Veglia, M Vendruscolo
Biochemistry
(2013)
52
(doi: 10.1021/bi400517b)
Characterization of the Interdomain Motions in Hen Lysozyme Using Residual Dipolar Couplings as Replica-Averaged Structural Restraints in Molecular Dynamics Simulations
A De Simone, RW Montalvao, CM Dobson, M Vendruscolo
Biochemistry
(2013)
52
(doi: 10.1021/bi4007513)
A Relationship between the Aggregation Rates of α‑Synuclein Variants and the β‑Sheet Populations in Their Monomeric Forms
C Camilloni, M Vendruscolo
The journal of physical chemistry. B
(2013)
117
(doi: 10.1021/jp405614j)
In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-synuclein within E. coli cells.
CA Waudby, C Camilloni, AWP Fitzpatrick, LD Cabrita, CM Dobson, M Vendruscolo, J Christodoulou
PloS one
(2013)
8
(doi: 10.1371/journal.pone.0072286)
Electrostatic origin of in vitro aggregation of human γ-crystallin
BG Mohr, CM Dobson, SC Garman, M Muthukumar
J Chem Phys
(2013)
139
(doi: 10.1063/1.4816367)
Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages
T Guilliams, F El-Turk, AK Buell, EM O'Day, FA Aprile, EK Esbjörner, M Vendruscolo, N Cremades, E Pardon, L Wyns, ME Welland, J Steyaert, J Christodoulou, CM Dobson, E De Genst
Journal of Molecular Biology
(2013)
425
(doi: 10.1016/j.jmb.2013.01.040)
Identification of small-molecule binding pockets in the soluble monomeric form of the Aβ42 peptide
M Zhu, A De Simone, D Schenk, G Toth, CM Dobson, M Vendruscolo
J Chem Phys
(2013)
139
(doi: 10.1063/1.4811831)
A geometrical parametrization of C1′-C5′ RNA ribose chemical shifts calculated by density functional theory
R Suardíaz, AB Sahakyan, M Vendruscolo
The Journal of chemical physics
(2013)
139
(doi: 10.1063/1.4811498)
MD simulations of intrinsically disordered proteins with replica-averaged chemical shift restraints
B Fu, C Camilloni, A Cavalli, M Vendruscolo
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2013)
42
Yusuf Hamied Department of Chemistry
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