Centre for Misfolding Diseases

Publications

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  • Currently displaying 1521 - 1540 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster.
JR Kumita, L Helmfors, J Williams, LM Luheshi, L Menzer, M Dumoulin, DA Lomas, DC Crowther, CM Dobson, A-C Brorsson
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
(2011)
26
(doi: 10.1096/fj.11-185983)
Als mutations in FUS cause neuronal dysfunction and death in caenorhabditis elegans by a dominant gain-of-function mechanism
T Murakami, S-P Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, J Robertson, H Suzuki, GG Tartaglia, M Vendruscolo, GS Kaminski Schierle, FTS Chan, A Moloney, D Crowther, CF Kaminski, M Zhen, P St George-Hyslop
Human Molecular Genetics
(2011)
21
(doi: 10.1093/hmg/ddr417)
Excited-state control of protein activity
M Vendruscolo
Journal of Molecular Biology
(2011)
412
(doi: 10.1016/j.jmb.2011.07.047)
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
International Journal of Molecular Sciences
(2011)
12
(doi: 10.3390/ijms12095844)
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
International Journal of Molecular Sciences
(2011)
12
(doi: 10.3390/ijms12095844)
Using Side‐Chain Aromatic Proton Chemical Shifts for a Quantitative Analysis of Protein Structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie
(2011)
123
(doi: 10.1002/ange.201101641)
On the effect of Trigger Factor on nascent chain protein folding off of the ribosome
EP O'Brien, M Vendruscolo, CM Dobson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2011)
242
Observation of spatial propagation of amyloid assembly from single nuclei
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
Proceedings of the National Academy of Sciences
(2011)
108
(doi: 10.1073/pnas.1105555108)
Metastability of native proteins and the phenomenon of amyloid formation.
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
Journal of the American Chemical Society
(2011)
133
(doi: 10.1021/ja2017703)
Intermolecular structure determination of amyloid fibrils with magic-angle spinning and dynamic nuclear polarization NMR.
MJ Bayro, GT Debelouchina, MT Eddy, NR Birkett, CE MacPhee, M Rosay, WE Maas, CM Dobson, RG Griffin
Journal of the American Chemical Society
(2011)
133
(doi: 10.1021/ja203756x)
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608918)
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
Journal of Molecular Biology
(2011)
411
(doi: 10.1016/j.jmb.2011.05.046)
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608917)
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608916)
Direct radiolabelling of proteins at cysteine using [ 18 F]-fluorosugars
O Boutureira, GJL Bernardes, F D'Hooge, BG Davis
Chemical communications (Cambridge, England)
(2011)
47
(doi: 10.1039/c1cc13524d)
Methods for converting cysteine to dehydroalanine on peptides and proteins
JM Chalker, SB Gunnoo, O Boutureira, SC Gerstberger, M Fernández-González, GJL Bernardes, L Griffin, H Hailu, CJ Schofield, BG Davis
Chemical Science
(2011)
2
(doi: 10.1039/c1sc00185j)
Protein solubility and protein homeostasis: a generic view of protein misfolding disorders.
M Vendruscolo, TPJ Knowles, CM Dobson
Cold Spring Harb Perspect Biol
(2011)
3
(doi: 10.1101/cshperspect.a010454)
The A53T Mutation is Key in Defining the Differences in the Aggregation Kinetics of Human and Mouse α-Synuclein
L Kang, K-P Wu, M Vendruscolo, J Baum
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja203979j)
In situ measurements of the formation and morphology of intracellular β-amyloid fibrils by super-resolution fluorescence imaging.
GS Kaminski Schierle, S van de Linde, M Erdelyi, EK Esbjörner, T Klein, E Rees, CW Bertoncini, CM Dobson, M Sauer, CF Kaminski
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja201651w)
Structure-based prediction of methyl chemical shifts in proteins
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Journal of Biomolecular NMR
(2011)
50
(doi: 10.1007/s10858-011-9524-2)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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