Centre for Misfolding Diseases

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  • Currently displaying 1521 - 1540 of 2489 publications
Author(s)
Publication title
Journal Name
Publication year
Highly Non-linear Microfluidic Resistor Elements for Flow Rate-dependent Addressing of Microchannels
L Rajah, DA White, TPJ Knowles
International Journal of Nonlinear Sciences and Numerical Simulation
(2012)
13
(doi: 10.1515/ijnsns-2012-0401)
NMR chemical shifts and protein dynamics
C Camilloni, M Vendruscolo
FEBS JOURNAL
(2012)
279
In support of the BMRB.
JL Markley, H Akutsu, T Asakura, M Baldus, R Boelens, A Bonvin, R Kaptein, A Bax, I Bezsonova, MR Gryk, JC Hoch, DM Korzhnev, MW Maciejewski, D Case, WJ Chazin, TA Cross, S Dames, H Kessler, O Lange, T Madl, B Reif, M Sattler, D Eliezer, A Fersht, J Forman-Kay, LE Kay, J Fraser, J Gross, T Kortemme, A Sali, T Fujiwara, K Gardner, X Luo, J Rizo-Rey, M Rosen, RR Gil, C Ho, G Rule, AM Gronenborn, R Ishima, J Klein-Seetharaman, P Tang, P van der Wel, Y Xu, S Grzesiek, S Hiller, J Seelig, ED Laue, H Mott, D Nietlispach, I Barsukov, L-Y Lian, D Middleton, T Blumenschein, G Moore, I Campbell, J Schnell, IJ Vakonakis, A Watts, MR Conte, J Mason, M Pfuhl, MR Sanderson, J Craven, M Williamson, C Dominguez, G Roberts, U Günther, M Overduin, J Werner, P Williamson, C Blindauer, M Crump, P Driscoll, T Frenkiel, A Golovanov, S Matthews, J Parkinson, D Uhrin, M Williams, D Neuhaus, H Oschkinat, A Ramos, DE Shaw, C Steinbeck, M Vendruscolo, GW Vuister, KJ Walters, H Weinstein, K Wüthrich, S Yokoyama
Nature structural & molecular biology
(2012)
19
(doi: 10.1038/nsmb.2371)
Fluctuations in water, the hydrophobic effect and self-assembly
PS Varilly, AJ Patel, SN Jamadagni, H Acharya, MF Hagan, S Garde, D Chandler, TPJ Knowles, D Frenkel
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
244
Co-translational folding of E. coli's cytosolic proteome exhibits kinetic effects that can significantly delay folding
P Ciryam, M Vendruscolo, CM Dobson, EP O'Brien
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
244
Sequence-based prediction of protein solubility
F Agostini, M Vendruscolo, GG Tartaglia
Journal of Molecular Biology
(2012)
421
(doi: 10.1016/j.jmb.2011.12.005)
From macroscopic measurements to microscopic mechanisms of protein aggregation
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
Journal of Molecular Biology
(2012)
421
(doi: 10.1016/j.jmb.2012.02.031)
ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load.
JE Chambers, K Petrova, G Tomba, M Vendruscolo, D Ron
J Cell Biol
(2012)
198
(doi: 10.1083/jcb.201202005)
Determination of structural fluctuations of proteins from structure-based calculations of residual dipolar couplings
RW Montalvao, A De Simone, M Vendruscolo
Journal of Biomolecular NMR
(2012)
53
(doi: 10.1007/s10858-012-9644-3)
Fibrillogenic propensity of the GroEL apical domain
J Chen, H Yagi, P Sormanni, M Vendruscolo, K Makabe, T Nakamura, Y Goto, K Kuwajima
PROTEIN SCIENCE
(2012)
21
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers
B Mannini, R Cascella, M Zampagni, M van Waarde-Verhagen, S Meehan, C Roodveldt, S Campioni, M Boninsegna, A Penco, A Relini, HH Kampinga, CM Dobson, MR Wilson, C Cecchi, F Chiti
Proceedings of the National Academy of Sciences of the United States of America
(2012)
109
(doi: 10.1073/pnas.1117799109)
Rapid distinction of intracellular and extracellular proteins using NMR diffusion measurements
CA Waudby, MD Mantle, LD Cabrita, LF Gladden, CM Dobson, J Christodoulou
J Am Chem Soc
(2012)
134
(doi: 10.1021/ja304912c)
Generation of Carbon Monoxide Releasing Molecules (CO-RMs) as Drug Candidates for the Treatment of Acute Liver Injury: Targeting of CO-RMs to the Liver
AR Marques, L Kromer, DJ Gallo, N Penacho, SS Rodrigues, JD Seixas, GJL Bernardes, PM Reis, SL Otterbein, RA Ruggieri, ASG Gonçalves, AML Gonçalves, MN De Matos, I Bento, LE Otterbein, WA Blättler, CC Romão
Organometallics
(2012)
31
(doi: 10.1021/om300360c)
Trigger Factor Slows Co-translational Folding through Kinetic Trapping while Sterically Protecting the Nascent Chain from Aberrant Cytosolic Interactions
EP O'Brien, J Christodoulou, M Vendruscolo, CM Dobson
Journal of the American Chemical Society
(2012)
134
(doi: 10.1021/ja302305u)
Fucose -specific conjugation of hydrazide derivatives to a vascular-targeting monoclonal antibody in IgG format
K Zuberbühler, G Casi, GJL Bernardes, D Neri
Chemical communications (Cambridge, England)
(2012)
48
(doi: 10.1039/c2cc32412a)
Selenium-enhanced electron microscopic imaging of different aggregate forms of a segment of the amyloid β peptide in cells
EK McGuire, M Motskin, B Bolognesi, SD Bergin, TPJ Knowles, J Skepper, LM Luheshi, DW McComb, CM Dobson, AE Porter
ACS Nano
(2012)
6
(doi: 10.1021/nn204859e)
Characterizing intermolecular interactions that initiate native-like protein aggregation.
F Bemporad, A De Simone, F Chiti, CM Dobson
Biophysical Journal
(2012)
102
(doi: 10.1016/j.bpj.2012.03.057)
Prediction of variable translation rate effects on cotranslational protein folding.
EP O'Brien, M Vendruscolo, CM Dobson
Nature Communications
(2012)
3
(doi: 10.1038/ncomms1850)
Direct observation of the interconversion of normal and toxic forms of α-synuclein.
N Cremades, SIA Cohen, E Deas, AY Abramov, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, NW Wood, TPJ Knowles, CM Dobson, D Klenerman
Cell
(2012)
149
(doi: 10.1016/j.cell.2012.03.037)
Role of elongation and secondary pathways in S6 amyloid fibril growth.
N Lorenzen, SIA Cohen, SB Nielsen, TW Herling, G Christiansen, CM Dobson, TPJ Knowles, D Otzen
Biophysical journal
(2012)
102
(doi: 10.1016/j.bpj.2012.03.047)
Yusuf Hamied Department of Chemistry
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