Centre for Misfolding Diseases

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  • Currently displaying 1521 - 1540 of 2453 publications
Author(s)
Publication title
Journal Name
Publication year
Protein structure validation using side-chain chemical shifts.
AB Sahakyan, A Cavalli, WF Vranken, M Vendruscolo
The journal of physical chemistry. B
(2012)
116
(doi: 10.1021/jp2122054)
Chemical site-selective protein modification: Development of a traceless vascular targeting ADC for cancer therapy
GJL Bernardes, D Neri, BG Davis
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
243
Mechanism of Non-Specific Inhibitors of Amyloid Assembly: Interactions of Lacmoid with the Amyloid Beta Peptide
A Abelein, B Bolognesi, CM Dobson, A Gräslund, C Lendel
Biophysical Journal
(2012)
102
(doi: 10.1016/j.bpj.2011.11.2417)
Co-translational folding of E. coli's cytosolic proteome exhibits kinetic effects that can significantly delay folding
P Ciryam, M Vendruscolo, CM Dobson, EP O'Brien
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
244
Investigating the Factors Affecting the Aggregation of Alpha-Synuclein using Single Molecule Fluorescence and Fast Flow Microfluidics
MH Horrocks, N Cremades, L Tosatto, T Guilliams, E De Genst, J-U Shim, CM Dobson, D Klenerman
Biophysical Journal
(2012)
102
(doi: 10.1016/j.bpj.2011.11.1407)
Building well-defined glycoproteins
GJL Bernardes, BG Davis
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
243
Fluctuations in water, the hydrophobic effect and self-assembly
PS Varilly, AJ Patel, SN Jamadagni, H Acharya, MF Hagan, S Garde, D Chandler, TPJ Knowles, D Frenkel
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
244
Nanobodies as structural probes of protein misfolding and fibril formation
E De Genst, CM Dobson
Methods in Molecular Biology
(2012)
911
(doi: 10.1007/978-1-61779-968-6_34)
Selenenylsulfide-Linked Homogeneous Glycopeptides and Glycoproteins: Synthesis of Human "Hepatic Se Metabolite A"
O Boutureira, GJL Bernardes, M Fernández-González, DC Anthony, BG Davis
Angew Chem Int Ed Engl
(2011)
51
(doi: 10.1002/anie.201106658)
A traceless vascular-targeting antibody-drug conjugate for cancer therapy.
GJL Bernardes, G Casi, S Trüssel, I Hartmann, K Schwager, J Scheuermann, D Neri
Angewandte Chemie International Edition
(2011)
51
(doi: 10.1002/anie.201106527)
Hydrophobicity and conformational change as mechanistic determinants for nonspecific modulators of amyloid β self-assembly.
A Abelein, B Bolognesi, CM Dobson, A Gräslund, C Lendel
Biochemistry
(2011)
51
(doi: 10.1021/bi201745g)
Experimental free energy surfaces reveal the mechanisms of maintenance of protein solubility
A De Simone, A Dhulesia, G Soldi, M Vendruscolo, S-TD Hsu, F Chiti, CM Dobson
Proceedings of the National Academy of Sciences of the United States of America
(2011)
108
(doi: 10.1073/pnas.1112197108)
Clusterin facilitates in vivo clearance of extracellular misfolded proteins
AR Wyatt, JJ Yerbury, P Berghofer, I Greguric, A Katsifis, CM Dobson, MR Wilson
Cellular and Molecular Life Sciences
(2011)
68
(doi: 10.1007/s00018-011-0684-8)
Protein solubility and protein homeostasis: A generic view of protein misfolding disorders
M Vendruscolo, TPJ Knowles, CM Dobson
Cold Spring Harbor Perspectives in Biology
(2011)
3
(doi: 10.1101/cshperspect.a010454)
Determination of conformational equilibria in proteins using residual dipolar couplings
A De Simone, RW Montalvao, M Vendruscolo
Journal of chemical theory and computation
(2011)
7
(doi: 10.1021/ct200361b)
Coarse-grained model for protein folding based on structural profiles.
K Wolff, M Vendruscolo, M Porto
Physical review. E, Statistical, nonlinear, and soft matter physics
(2011)
84
(doi: 10.1103/PhysRevE.84.041934)
Introduction
M Buchanan, G Caldarelli, PDL Rios, F Rao, M Vendruscolo
(2011)
171
(doi: 10.1017/CBO9780511845086.001)
Probing small molecule binding to amyloid fibrils
AK Buell, EK Esbjörner, PJ Riss, DA White, FI Aigbirhio, G Toth, ME Welland, CM Dobson, TPJ Knowles
Phys Chem Chem Phys
(2011)
13
(doi: 10.1039/c1cp22283j)
Inversion of the Balance between Hydrophobic and Hydrogen Bonding Interactions in Protein Folding and Aggregation.
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
Plos Computational Biology
(2011)
7
(doi: 10.1371/journal.pcbi.1002169)
Binding of the molecular chaperone αb-crystallin to Aβ amyloid fibrils inhibits fibril elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
Biophys J
(2011)
101
(doi: 10.1016/j.bpj.2011.07.056)
Yusuf Hamied Department of Chemistry
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