Centre for Misfolding Diseases

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  • Currently displaying 1601 - 1620 of 2523 publications
Author(s)
Publication title
Journal Name
Publication year
Hydrophobicity and Conformational Change as Mechanistic Determinants for Nonspecific Modulators of Amyloid β Self-Assembly
A Abelein, B Bolognesi, CM Dobson, A Gräslund, C Lendel
Biochemistry
(2011)
51
(doi: 10.1021/bi201745g)
Experimental free energy surfaces reveal the mechanisms of maintenance of protein solubility.
A De Simone, A Dhulesia, G Soldi, M Vendruscolo, S-TD Hsu, F Chiti, CM Dobson
Proceedings of the National Academy of Sciences of the United States of America
(2011)
108
(doi: 10.1073/pnas.1112197108)
Clusterin facilitates in vivo clearance of extracellular misfolded proteins
AR Wyatt, JJ Yerbury, P Berghofer, I Greguric, A Katsifis, CM Dobson, MR Wilson
Cellular and Molecular Life Sciences
(2011)
68
(doi: 10.1007/s00018-011-0684-8)
Protein solubility and protein homeostasis: A generic view of protein misfolding disorders
M Vendruscolo, TPJ Knowles, CM Dobson
Cold Spring Harbor Perspectives in Biology
(2011)
3
(doi: 10.1101/cshperspect.a010454)
Determination of Conformational Equilibria in Proteins Using Residual Dipolar Couplings
A De Simone, RW Montalvao, M Vendruscolo
Journal of Chemical Theory and Computation
(2011)
7
(doi: 10.1021/ct200361b)
Coarse-grained model for protein folding based on structural profiles.
K Wolff, M Vendruscolo, M Porto
Phys Rev E Stat Nonlin Soft Matter Phys
(2011)
84
(doi: 10.1103/PhysRevE.84.041934)
Coarse-grained model for protein folding based on structural profiles
K Wolff, M Vendruscolo, M Porto
Physical Review E Statistical Nonlinear and Soft Matter Physics
(2011)
84
(doi: 10.1103/physreve.84.041934)
Introduction
M Buchanan, G Caldarelli, PDL Rios, F Rao, M Vendruscolo
(2011)
171
(doi: 10.1017/cbo9780511845086.001)
Probing small molecule binding to amyloid fibrils.
AK Buell, EK Esbjörner, PJ Riss, DA White, FI Aigbirhio, G Toth, ME Welland, CM Dobson, TPJ Knowles
Phys Chem Chem Phys
(2011)
13
(doi: 10.1039/c1cp22283j)
Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
PLoS computational biology
(2011)
7
(doi: 10.1371/journal.pcbi.1002169)
Binding of the Molecular Chaperone αB-Crystallin to Aβ Amyloid Fibrils Inhibits Fibril Elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
Biophysical Journal
(2011)
101
(doi: 10.1016/j.bpj.2011.07.056)
Using side-chain aromatic proton chemical shifts for a quantitative analysis of protein structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie International Edition
(2011)
50
(doi: 10.1002/anie.201101641)
Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster.
JR Kumita, L Helmfors, J Williams, LM Luheshi, L Menzer, M Dumoulin, DA Lomas, DC Crowther, CM Dobson, A-C Brorsson
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
(2011)
26
(doi: 10.1096/fj.11-185983)
ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism
T Murakami, S-P Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, J Robertson, H Suzuki, GG Tartaglia, M Vendruscolo, GS Kaminski Schierle, FTS Chan, A Moloney, D Crowther, CF Kaminski, M Zhen, P St George-Hyslop
Human Molecular Genetics
(2011)
21
(doi: 10.1093/hmg/ddr417)
Excited-state control of protein activity
M Vendruscolo
Journal of Molecular Biology
(2011)
412
(doi: 10.1016/j.jmb.2011.07.047)
Nucleated polymerisation in the presence of pre-formed seed filaments.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
International Journal of Molecular Sciences
(2011)
12
(doi: 10.3390/ijms12095844)
Using Side‐Chain Aromatic Proton Chemical Shifts for a Quantitative Analysis of Protein Structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie
(2011)
123
(doi: 10.1002/ange.201101641)
On the effect of Trigger Factor on nascent chain protein folding off of the ribosome
EP O'Brien, M Vendruscolo, CM Dobson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2011)
242
Observation of spatial propagation of amyloid assembly from single nuclei
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
Proceedings of the National Academy of Sciences of the United States of America
(2011)
108
(doi: 10.1073/pnas.1105555108)
Metastability of Native Proteins and the Phenomenon of Amyloid Formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja2017703)
Yusuf Hamied Department of Chemistry
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