Centre for Misfolding Diseases

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  • Currently displaying 1601 - 1620 of 2508 publications
Author(s)
Publication title
Journal Name
Publication year
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
International Journal of Molecular Sciences
(2011)
12
(doi: 10.3390/ijms12095844)
Using Side‐Chain Aromatic Proton Chemical Shifts for a Quantitative Analysis of Protein Structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie
(2011)
123
(doi: 10.1002/ange.201101641)
On the effect of Trigger Factor on nascent chain protein folding off of the ribosome
EP O'Brien, M Vendruscolo, CM Dobson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2011)
242
Observation of spatial propagation of amyloid assembly from single nuclei.
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
Proceedings of the National Academy of Sciences
(2011)
108
(doi: 10.1073/pnas.1105555108)
Metastability of Native Proteins and the Phenomenon of Amyloid Formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
Journal of the American Chemical Society
(2011)
133
(doi: 10.1021/ja2017703)
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608918)
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608916)
Intermolecular structure determination of amyloid fibrils with magic-angle spinning and dynamic nuclear polarization NMR
MJ Bayro, GT Debelouchina, MT Eddy, NR Birkett, CE MacPhee, M Rosay, WE Maas, CM Dobson, RG Griffin
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja203756x)
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608917)
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
Journal of Molecular Biology
(2011)
411
(doi: 10.1016/j.jmb.2011.05.046)
Direct radiolabelling of proteins at cysteine using [ 18 F]-fluorosugars
O Boutureira, GJL Bernardes, F D'Hooge, BG Davis
Chem Commun (Camb)
(2011)
47
(doi: 10.1039/c1cc13524d)
The A53T Mutation is Key in Defining the Differences in the Aggregation Kinetics of Human and Mouse alpha-Synuclein
L Kang, K-P Wu, M Vendruscolo, J Baum
Journal of the American Chemical Society
(2011)
133
(doi: 10.1021/ja203979j)
Methods for converting cysteine to dehydroalanine on peptides and proteins
JM Chalker, SB Gunnoo, O Boutureira, SC Gerstberger, M Fernández-González, GJL Bernardes, L Griffin, H Hailu, CJ Schofield, BG Davis
Chemical Science
(2011)
2
(doi: 10.1039/c1sc00185j)
In situ measurements of the formation and morphology of intracellular β-amyloid fibrils by super-resolution fluorescence imaging.
GS Kaminski Schierle, S van de Linde, M Erdelyi, EK Esbjörner, T Klein, E Rees, CW Bertoncini, CM Dobson, M Sauer, CF Kaminski
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja201651w)
Structure-based prediction of methyl chemical shifts in proteins
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Journal of Biomolecular NMR
(2011)
50
(doi: 10.1007/s10858-011-9524-2)
Kinetics of protein aggregation
T Knowles, M Vendruscolo, C Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Insights into the molecular mechanisms of Hsp70-mediated inhibition of amyloid formation
FA Aprile, A Dhulesia, F Stengel, T Eliseo, C Roodvelt, B Bolognesi, P Tortora, X Salvatella, N Cremades, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Direct observation of the interconversion of normal and pathogenic forms of alpha-synuclein
N Cremades, SIA Cohen, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, TPJ Knowles, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Characterizing the amyloidogenic state of the acylphosphatase from Sulfolobus solfataricus
F Bemporad, A De Simone, F Chiti, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Towards Improved Therapeutic CORMs: Understanding the Reactivity of CORM-3 with Proteins
T Santos-Silva, A Mukhopadhyay, JD Seixas, GJL Bernardes, CC Romão, MJ Romão
Curr Med Chem
(2011)
18
(doi: 10.2174/092986711796504583)
Yusuf Hamied Department of Chemistry
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