Centre for Misfolding Diseases

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  • Currently displaying 1601 - 1620 of 2454 publications
Author(s)
Publication title
Journal Name
Publication year
Local cooperativity in an amyloidogenic state of human lysozyme observed at atomic resolution.
A Dhulesia, N Cremades, JR Kumita, S-TD Hsu, MF Mossuto, M Dumoulin, D Nietlispach, M Akke, X Salvatella, CM Dobson
Journal of the American Chemical Society
(2010)
132
(doi: 10.1021/ja103524m)
Derivation of a solubility condition for proteins from an analysis of the competition between folding and aggregation
S Pechmann, M Vendruscolo
Molecular Omics
(2010)
6
(doi: 10.1039/c005160h)
Accurate Determination of Interstrand Distances and Alignment in Amyloid Fibrils by Magic Angle Spinning NMR
MA Caporini, VS Bajaj, M Veshtort, A Fitzpatrick, CE MacPhee, M Vendruscolo, CM Dobson, RG Griffin
Journal of Physical Chemistry B
(2010)
114
(doi: 10.1021/jp106675h)
Enzymatic activity in disordered states of proteins
M Vendruscolo
Curr Opin Chem Biol
(2010)
14
(doi: 10.1016/j.cbpa.2010.08.022)
Characterization of the nucleation barriers for protein aggregation and amyloid formation
S Auer, CM Dobson, M Vendruscolo
All Life
(2010)
1
(doi: 10.2976/1.2760023)
Chemical and biophysical insights into the propagation of prion strains.
J Falsig, KP Nilsson, TPJ Knowles, A Aguzzi
Hfsp Journal
(2010)
2
(doi: 10.2976/1.2990786)
Design, synthesis and biological evaluation of carbohydrate -functionalized cyclodextrins and liposomes for hepatocyte -specific targeting
GJL Bernardes, R Kikkeri, M Maglinao, P Laurino, M Collot, SY Hong, B Lepenies, PH Seeberger
Organic & Biomolecular Chemistry
(2010)
8
(doi: 10.1039/c0ob00372g)
Functional interactions as a survival strategy against abnormal aggregation
L Masino, G Nicastro, L Calder, M Vendruscolo, A Pastore
The FASEB Journal
(2010)
25
(doi: 10.1096/fj.10-161208)
Stabilization of neurotoxic Alzheimer amyloid-β oligomers by protein engineering
A Sandberg, LM Luheshi, S Söllvander, T Pereira de Barros, B Macao, TPJ Knowles, H Biverstål, C Lendel, F Ekholm-Petterson, A Dubnovitsky, L Lannfelt, CM Dobson, T Härd
Proceedings of the National Academy of Sciences of the United States of America
(2010)
107
(doi: 10.1073/pnas.1001740107)
Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins
O Boutureira, F D'Hooge, M Fernández-González, GJL Bernardes, M Sánchez-Navarro, JR Koeppe, BG Davis
Chemical Communications
(2010)
46
(doi: 10.1039/c0cc01576h)
Proteome-Level Interplay between Folding and Aggregation Propensities of Proteins
GG Tartaglia, M Vendruscolo
J Mol Biol
(2010)
402
(doi: 10.1016/j.jmb.2010.08.013)
High-resolution MAS NMR analysis of PI3-SH3 amyloid fibrils: Backbone conformation and implications for protofilament assembly and structure
MJ Bayro, T Maly, NR Birkett, CE Macphee, CM Dobson, RG Griffin
Biochemistry
(2010)
49
(doi: 10.1021/bi100864t)
Using NMR chemical shifts as structural restraints in molecular dynamics simulations of proteins.
P Robustelli, K Kohlhoff, A Cavalli, M Vendruscolo
Structure (London, England : 1993)
(2010)
18
(doi: 10.1016/j.str.2010.04.016)
Imaging Alzheimer's disease-related protein aggregates in human cells using a selenium label
EK McGuire, M Motskin, TPJ Knowles, CM Dobson, DW McComb, AE Porter
Journal of Physics: Conference Series
(2010)
241
(doi: 10.1088/1742-6596/241/1/012020)
Surface Attachment of Protein Fibrils via Covalent Modification Strategies
AK Buell, DA White, C Meier, ME Welland, TPJ Knowles, CM Dobson
The journal of physical chemistry. B
(2010)
114
(doi: 10.1021/jp101579n)
The Non-Core Regions of Human Lysozyme Amyloid Fibrils Influence Cytotoxicity
MF Mossuto, A Dhulesia, G Devlin, E Frare, JR Kumita, PP de Laureto, M Dumoulin, A Fontana, CM Dobson, X Salvatella
Journal of Molecular Biology
(2010)
402
(doi: 10.1016/j.jmb.2010.07.005)
Structure and properties of a complex of α-synuclein and a single-domain camelid antibody
EJ De Genst, T Guilliams, J Wellens, EM O'Day, CA Waudby, S Meehan, M Dumoulin, S-TD Hsu, N Cremades, KHG Verschueren, E Pardon, L Wyns, J Steyaert, J Christodoulou, CM Dobson
J Mol Biol
(2010)
402
(doi: 10.1016/j.jmb.2010.07.001)
Protein Misfolding Diseases: Current and Emerging Principles and Therapies
M Ramirez-Alvarado, JW Kelly, CM Dobson
Protein Misfolding Diseases Current and Emerging Principles and Therapies
(2010)
(doi: 10.1002/9780470572702)
A non-natural variant of human lysozyme (I59T) mimics the in vitro behaviour of the I56T variant that is responsible for a form of familial amyloidosis
CL Hagan, RJK Johnson, A Dhulesia, M Dumoulin, J Dumont, E De Genst, J Christodoulou, CV Robinson, CM Dobson, JR Kumita
Protein Eng Des Sel
(2010)
23
(doi: 10.1093/protein/gzq023)
ANS binding reveals common features of cytotoxic amyloid species
B Bolognesi, JR Kumita, TP Barros, EK Esbjorner, LM Luheshi, DC Crowther, MR Wilson, CM Dobson, G Favrin, JJ Yerbury
ACS Chemical Biology
(2010)
5
(doi: 10.1021/cb1001203)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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