Centre for Misfolding Diseases

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  • Currently displaying 1501 - 1520 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608917)
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608918)
Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars.
O Boutureira, GJL Bernardes, F D'Hooge, BG Davis
Chemical communications (Cambridge, England)
(2011)
47
(doi: 10.1039/c1cc13524d)
Methods for converting cysteine to dehydroalanine on peptides and proteins
JM Chalker, SB Gunnoo, O Boutureira, SC Gerstberger, M Fernández-González, GJL Bernardes, L Griffin, H Hailu, CJ Schofield, BG Davis
Chemical Science
(2011)
2
(doi: 10.1039/c1sc00185j)
The A53T mutation is key in defining the differences in the aggregation kinetics of human and mouse α-synuclein.
L Kang, K-P Wu, M Vendruscolo, J Baum
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja203979j)
In Situ Measurements of the Formation and Morphology of Intracellular beta-Amyloid Fibrils by Super-Resolution Fluorescence Imaging
GS Kaminski Schierle, S van de Linde, M Erdelyi, EK Esbjörner, T Klein, E Rees, CW Bertoncini, CM Dobson, M Sauer, CF Kaminski
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja201651w)
Towards improved therapeutic CORMs: Understanding the reactivity of CORM-3 with proteins
T Santos-Silva, A Mukhopadhyay, JD Seixas, GJL Bernardes, CC Romão, MJ Romão
Curr Med Chem
(2011)
18
(doi: 10.2174/092986711796504583)
Characterizing the amyloidogenic state of the acylphosphatase from Sulfolobus solfataricus
F Bemporad, A De Simone, F Chiti, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Insights into the molecular mechanisms of Hsp70-mediated inhibition of amyloid formation
FA Aprile, A Dhulesia, F Stengel, T Eliseo, C Roodvelt, B Bolognesi, P Tortora, X Salvatella, N Cremades, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Direct observation of the interconversion of normal and pathogenic forms of α-synuclein
N Cremades, SIA Cohen, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, TPJ Knowles, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Kinetics of protein aggregation
T Knowles, M Vendruscolo, C Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Structure-based prediction of methyl chemical shifts in proteins
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Journal of Biomolecular NMR
(2011)
50
(doi: 10.1007/s10858-011-9524-2)
Nanomechanics of functional and pathological amyloid materials
TPJ Knowles, MJ Buehler
Nature nanotechnology
(2011)
6
(doi: 10.1038/nnano.2011.102)
Native-State stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris
G Whyteside, MJC Alcocer, JR Kumita, CM Dobson, M Lazarou, RJ Pleass, DB Archer
PloS one
(2011)
6
(doi: 10.1371/journal.pone.0022692)
Using Chemical Shifts to Determine Structural Changes in Proteins upon Complex Formation
A Cavalli, RW Montalvao, M Vendruscolo
J Phys Chem B
(2011)
115
(doi: 10.1021/jp202647q)
Nucleated polymerisation in the presence of pre-formed seed filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
(2011)
(doi: 10.48550/arxiv.1107.1454)
The iFly tracking system for an automated locomotor and behavioural analysis of Drosophila melanogaster.
KJ Kohlhoff, TR Jahn, DA Lomas, CM Dobson, DC Crowther, M Vendruscolo
Integrative Biology
(2011)
3
(doi: 10.1039/c0ib00149j)
P4‐316: Stabilization of neurotoxic Alzheimer amyloid‐beta oligomers by protein engineering
A Dubnovitsky, A Sandberg, L Luheshi, S Söllvander, TP de Barros, B Macao, T Knowles, H Biverstål, C Lendel, F Ekholm‐Petterson, L Lannfelt, C Dobson, T Härd
Alzheimer's & Dementia
(2011)
7
(doi: 10.1016/j.jalz.2011.09.061)
The statistical theory of allostery
M Vendruscolo
Nat Chem Biol
(2011)
7
(doi: 10.1038/nchembio.603)
Disulfide bonds reduce the toxicity of the amyloid fibrils formed by an extracellular protein
MF Mossuto, B Bolognesi, B Guixer, A Dhulesia, F Agostini, JR Kumita, GG Tartaglia, M Dumoulin, CM Dobson, X Salvatella
Angewandte Chemie International Edition
(2011)
50
(doi: 10.1002/anie.201100986)
Yusuf Hamied Department of Chemistry
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