Centre for Misfolding Diseases

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  • Currently displaying 1501 - 1520 of 2520 publications
Author(s)
Publication title
Journal Name
Publication year
Cucurbit[8]uril and Blue-Box: High-Energy Water Release Overwhelms Electrostatic Interactions
F Biedermann, M Vendruscolo, OA Scherman, A De Simone, WM Nau
Journal of the American Chemical Society
(2013)
135
(doi: 10.1021/ja407951x)
A Nanobody Binding to Non-Amyloidogenic Regions of the Protein Human Lysozyme Enhances Partial Unfolding but Inhibits Amyloid Fibril Formation
E De Genst, P-H Chan, E Pardon, S-TD Hsu, JR Kumita, J Christodoulou, L Menzer, DY Chirgadze, CV Robinson, S Muyldermans, A Matagne, L Wyns, CM Dobson, M Dumoulin
The journal of physical chemistry. B
(2013)
117
(doi: 10.1021/jp403425z)
Subdomain architecture and stability of a giant repeat protein.
M Tsytlonok, P Sormanni, PJE Rowling, M Vendruscolo, LS Itzhaki
The journal of physical chemistry. B
(2013)
117
(doi: 10.1021/jp402360x)
Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase
A Pica, A Merlino, AK Buell, TPJ Knowles, E Pizzo, G D'Alessio, F Sica, L Mazzarella
Acta Crystallographica Section D, Structural Biology
(2013)
69
(doi: 10.1107/s0907444913020507)
Structures of the excited states of phospholamban and shifts in their populations upon phosphorylation
A De Simone, M Gustavsson, RW Montalvao, L Shi, G Veglia, M Vendruscolo
Biochemistry
(2013)
52
(doi: 10.1021/bi400517b)
Characterization of the interdomain motions in hen lysozyme using residual dipolar couplings as replica-averaged structural restraints in molecular dynamics simulations
A De Simone, RW Montalvao, CM Dobson, M Vendruscolo
Biochemistry
(2013)
52
(doi: 10.1021/bi4007513)
A relationship between the aggregation rates of α-synuclein variants and the β-sheet populations in their monomeric forms
C Camilloni, M Vendruscolo
The journal of physical chemistry. B
(2013)
117
(doi: 10.1021/jp405614j)
In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-synuclein within E. coli cells.
CA Waudby, C Camilloni, AWP Fitzpatrick, LD Cabrita, CM Dobson, M Vendruscolo, J Christodoulou
Plos One
(2013)
8
(doi: 10.1371/journal.pone.0072286)
Electrostatic origin of in vitro aggregation of human γ-crystallin
BG Mohr, CM Dobson, SC Garman, M Muthukumar
Journal of Chemical Physics
(2013)
139
(doi: 10.1063/1.4816367)
Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages
T Guilliams, F El-Turk, AK Buell, EM O'Day, FA Aprile, EK Esbjörner, M Vendruscolo, N Cremades, E Pardon, L Wyns, ME Welland, J Steyaert, J Christodoulou, CM Dobson, E De Genst
Journal of Molecular Biology
(2013)
425
(doi: 10.1016/j.jmb.2013.01.040)
Identification of small-molecule binding pockets in the soluble monomeric form of the Aβ42 peptide.
M Zhu, A De Simone, D Schenk, G Toth, CM Dobson, M Vendruscolo
J Chem Phys
(2013)
139
(doi: 10.1063/1.4811831)
A geometrical parametrization of C1'-C5' RNA ribose chemical shifts calculated by density functional theory.
R Suardíaz, AB Sahakyan, M Vendruscolo
The Journal of chemical physics
(2013)
139
(doi: 10.1063/1.4811498)
Using single molecule techniques to find out how the major protein associated with Parkinson's disease
MH Horrocks, L Tosatto, N Cremades, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2013)
42
Chemoselective transformations for bioimaging and targeted therapeutics
GJL Bernardes
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2013)
42
MD simulations of intrinsically disordered proteins with replica-averaged chemical shift restraints
B Fu, C Camilloni, A Cavalli, M Vendruscolo
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2013)
42
Hsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain.
FA Aprile, A Dhulesia, F Stengel, C Roodveldt, JLP Benesch, P Tortora, CV Robinson, X Salvatella, CM Dobson, N Cremades
Plos One
(2013)
8
(doi: 10.1371/journal.pone.0067961)
Single-molecule measurements of transient biomolecular complexes through microfluidic dilution.
MH Horrocks, L Rajah, P Jönsson, M Kjaergaard, M Vendruscolo, TPJ Knowles, D Klenerman
Anal Chem
(2013)
85
(doi: 10.1021/ac4010875)
A method of determining RNA conformational ensembles using structure-based calculations of residual dipolar couplings
AN Borkar, A De Simone, RW Montalvao, M Vendruscolo
Journal of Chemical Physics
(2013)
138
(doi: 10.1063/1.4804301)
α-Synuclein senses lipid packing defects and induces lateral expansion of lipids leading to membrane remodeling
MM Ouberai, J Wang, MJ Swann, C Galvagnion, T Guilliams, CM Dobson, ME Welland
Journal of Biological Chemistry
(2013)
288
(doi: 10.1074/jbc.m113.478297)
Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism.
SIA Cohen, S Linse, LM Luheshi, E Hellstrand, DA White, L Rajah, DE Otzen, M Vendruscolo, CM Dobson, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2013)
110
(doi: 10.1073/pnas.1218402110)
Yusuf Hamied Department of Chemistry
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