Centre for Misfolding Diseases

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  • Currently displaying 1561 - 1580 of 2453 publications
Author(s)
Publication title
Journal Name
Publication year
Towards improved therapeutic CORMs: understanding the reactivity of CORM-3 with proteins
T Santos-Silva, A Mukhopadhyay, JD Seixas, GJL Bernardes, CC Romão, MJ Romão
Curr Med Chem
(2011)
18
(doi: 10.2174/092986711796504583)
Characterizing the amyloidogenic state of the acylphosphatase from Sulfolobus solfataricus
F Bemporad, A De Simone, F Chiti, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Insights into the molecular mechanisms of Hsp70-mediated inhibition of amyloid formation
FA Aprile, A Dhulesia, F Stengel, T Eliseo, C Roodvelt, B Bolognesi, P Tortora, X Salvatella, N Cremades, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Direct observation of the interconversion of normal and pathogenic forms of α-synuclein
N Cremades, SIA Cohen, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, TPJ Knowles, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Nanomechanics of functional and pathological amyloid materials
TPJ Knowles, MJ Buehler
Nature Nanotechnology
(2011)
6
(doi: 10.1038/NNANO.2011.102)
Native-State stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris
G Whyteside, MJC Alcocer, JR Kumita, CM Dobson, M Lazarou, RJ Pleass, DB Archer
PLoS ONE
(2011)
6
(doi: 10.1371/journal.pone.0022692)
Using chemical shifts to determine structural changes in proteins upon complex formation.
A Cavalli, RW Montalvao, M Vendruscolo
The Journal of Physical Chemistry B
(2011)
115
(doi: 10.1021/jp202647q)
Nucleated polymerisation in the presence of pre-formed seed filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
(2011)
(doi: 10.48550/arxiv.1107.1454)
P4‐316: Stabilization of neurotoxic Alzheimer amyloid‐beta oligomers by protein engineering
A Dubnovitsky, A Sandberg, L Luheshi, S Söllvander, TP de Barros, B Macao, T Knowles, H Biverstål, C Lendel, F Ekholm‐Petterson, L Lannfelt, C Dobson, T Härd
Alzheimer's & Dementia
(2011)
7
(doi: 10.1016/j.jalz.2011.09.061)
The iFly tracking system for an automated locomotor and behavioural analysis of Drosophila melanogaster
KJ Kohlhoff, TR Jahn, DA Lomas, CM Dobson, DC Crowther, M Vendruscolo
Integrative biology : quantitative biosciences from nano to macro
(2011)
3
(doi: 10.1039/c0ib00149j)
Protein regulation: The statistical theory of allostery
M Vendruscolo
Nature chemical biology
(2011)
7
(doi: 10.1038/nchembio.603)
Disulfide bonds reduce the toxicity of the amyloid fibrils formed by an extracellular protein.
MF Mossuto, B Bolognesi, B Guixer, A Dhulesia, F Agostini, JR Kumita, GG Tartaglia, M Dumoulin, CM Dobson, X Salvatella
Angewandte Chemie (International ed. in English)
(2011)
50
(doi: 10.1002/anie.201100986)
Perturbation of the stability of amyloid fibrils through alteration of electrostatic interactions
SL Shammas, TPJ Knowles, AJ Baldwin, CE Macphee, ME Welland, CM Dobson, GL Devlin
Biophys J
(2011)
100
(doi: 10.1016/j.bpj.2011.04.039)
Solution-State Nuclear Magnetic Resonance Spectroscopy and Protein Folding
LD Cabrita, CA Waudby, CM Dobson, J Christodoulou
Methods in molecular biology (Clifton, N.J.)
(2011)
752
(doi: 10.1007/978-1-60327-223-0_7)
Probing protein aggregation with quartz crystal microbalances.
TPJ Knowles, GL Devlin, CM Dobson, ME Welland
Methods in molecular biology (Clifton, N.J.)
(2011)
752
(doi: 10.1007/978-1-60327-223-0_9)
Site-Selective Traceless Staudinger Ligation for Glycoprotein Synthesis Reveals Scope and Limitations
GJL Bernardes, L Linderoth, KJ Doores, O Boutureira, BG Davis
Chembiochem
(2011)
12
(doi: 10.1002/cbic.201100125)
A "Tag-and-Modify" Approach to Site-Selective Protein Modification
JM Chalker, GJL Bernardes, BG Davis
Acc Chem Res
(2011)
44
(doi: 10.1021/ar200056q)
Asymmetric folding pathways and transient misfolding in a coarse-grained model of proteins
K Wolff, M Vendruscolo, M Porto
EPL (Europhysics Letters)
(2011)
94
(doi: 10.1209/0295-5075/94/48005)
Population of nonnative states of lysozyme variants drives amyloid fibril formation
AK Buell, A Dhulesia, MF Mossuto, N Cremades, JR Kumita, M Dumoulin, ME Welland, TPJ Knowles, X Salvatella, CM Dobson
Journal of the American Chemical Society
(2011)
133
(doi: 10.1021/ja109620d)
Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease
TR Jahn, KJ Kohlhoff, M Scott, GG Tartaglia, DA Lomas, CM Dobson, M Vendruscolo, DC Crowther
Journal of Neuroscience Methods
(2011)
197
(doi: 10.1016/j.jneumeth.2011.01.026)
Yusuf Hamied Department of Chemistry
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