Centre for Misfolding Diseases

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  • Currently displaying 1581 - 1600 of 2489 publications
Author(s)
Publication title
Journal Name
Publication year
ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism
T Murakami, S-P Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, J Robertson, H Suzuki, GG Tartaglia, M Vendruscolo, GS Kaminski Schierle, FTS Chan, A Moloney, D Crowther, CF Kaminski, M Zhen, P St George-Hyslop
Human molecular genetics
(2011)
21
(doi: 10.1093/hmg/ddr417)
Excited-state control of protein activity
M Vendruscolo
Journal of Molecular Biology
(2011)
412
(doi: 10.1016/j.jmb.2011.07.047)
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
International journal of molecular sciences
(2011)
12
(doi: 10.3390/ijms12095844)
Using Side‐Chain Aromatic Proton Chemical Shifts for a Quantitative Analysis of Protein Structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie
(2011)
123
(doi: 10.1002/ange.201101641)
On the effect of Trigger Factor on nascent chain protein folding off of the ribosome
EP O'Brien, M Vendruscolo, CM Dobson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2011)
242
Observation of spatial propagation of amyloid assembly from single nuclei
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
Proceedings of the National Academy of Sciences of the United States of America
(2011)
108
(doi: 10.1073/pnas.1105555108)
Metastability of native proteins and the phenomenon of amyloid formation.
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
Journal of the American Chemical Society
(2011)
133
(doi: 10.1021/ja2017703)
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments.
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
The Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608916)
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608917)
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608918)
Intermolecular Structure Determination of Amyloid Fibrils with Magic-Angle Spinning and Dynamic Nuclear Polarization NMR
MJ Bayro, GT Debelouchina, MT Eddy, NR Birkett, CE MacPhee, M Rosay, WE Maas, CM Dobson, RG Griffin
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja203756x)
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
Journal of Molecular Biology
(2011)
411
(doi: 10.1016/j.jmb.2011.05.046)
Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars.
O Boutureira, GJL Bernardes, F D'Hooge, BG Davis
Chemical communications (Cambridge, England)
(2011)
47
(doi: 10.1039/c1cc13524d)
The A53T mutation is key in defining the differences in the aggregation kinetics of human and mouse α-synuclein.
L Kang, K-P Wu, M Vendruscolo, J Baum
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja203979j)
Methods for converting cysteine to dehydroalanine on peptides and proteins
JM Chalker, SB Gunnoo, O Boutureira, SC Gerstberger, M Fernández-González, GJL Bernardes, L Griffin, H Hailu, CJ Schofield, BG Davis
Chemical Science
(2011)
2
(doi: 10.1039/c1sc00185j)
In Situ Measurements of the Formation and Morphology of Intracellular beta-Amyloid Fibrils by Super-Resolution Fluorescence Imaging
GS Kaminski Schierle, S van de Linde, M Erdelyi, EK Esbjörner, T Klein, E Rees, CW Bertoncini, CM Dobson, M Sauer, CF Kaminski
Journal of the American Chemical Society
(2011)
133
(doi: 10.1021/ja201651w)
Characterizing the amyloidogenic state of the acylphosphatase from Sulfolobus solfataricus
F Bemporad, A De Simone, F Chiti, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Kinetics of protein aggregation
T Knowles, M Vendruscolo, C Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Structure-based prediction of methyl chemical shifts in proteins
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Journal of Biomolecular NMR
(2011)
50
(doi: 10.1007/s10858-011-9524-2)
Insights into the molecular mechanisms of Hsp70-mediated inhibition of amyloid formation
FA Aprile, A Dhulesia, F Stengel, T Eliseo, C Roodvelt, B Bolognesi, P Tortora, X Salvatella, N Cremades, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Yusuf Hamied Department of Chemistry
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