Centre for Misfolding Diseases

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  • Currently displaying 1581 - 1600 of 2403 publications
Author(s)
Publication title
Journal Name
Publication year
Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide.
A-C Brorsson, B Bolognesi, GG Tartaglia, SL Shammas, G Favrin, I Watson, DA Lomas, F Chiti, M Vendruscolo, CM Dobson, DC Crowther, LM Luheshi
Biophys J
(2010)
98
(doi: 10.1016/j.bpj.2009.12.4320)
Time averaging of NMR chemical shifts in the MLF peptide in the solid state.
I De Gortari, G Portella, X Salvatella, VS Bajaj, PCA van der Wel, JR Yates, MD Segall, CJ Pickard, MC Payne, M Vendruscolo
J Am Chem Soc
(2010)
132
(doi: 10.1021/ja9062629)
Effects of disease-associated mutations on the aggregation process of the 93-residue N-terminal fragment of human apolipoprotein A-I
S Raimondi, F Guglielmi, S Giorgetti, S Di Gaetano, A Arciello, A Relini, SM Doglia, A Natalello, P Pucci, P Mangione, L Obici, G Merlini, M Stoppini, GG Tartaglia, M Vendruscolo, R Piccoli, V Bellotti
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
(2010)
17
Chemical Protein Modification
GJL Bernardes, JM Chalker, BG Davis
(2010)
(doi: 10.1002/9783527630516.ch3)
Protein aggregation in crowded environments
DA White, AK Buell, TPJ Knowles, ME Welland, CM Dobson
J Am Chem Soc
(2010)
132
(doi: 10.1021/ja909997e)
Sequestration of the A beta Peptide Prevents Toxicity and Promotes Degradation In Vivo
LM Luheshi, W Hoyer, TP de Barros, I van Dijk Härd, A-C Brorsson, B Macao, C Persson, DC Crowther, DA Lomas, S Ståhl, CM Dobson, T Härd
PLoS biology
(2010)
8
(doi: 10.1371/journal.pbio.1000334)
The Interaction of αB-Crystallin with Mature α-Synuclein Amyloid Fibrils Inhibits Their Elongation
CA Waudby, TPJ Knowles, GL Devlin, JN Skepper, H Ecroyd, JA Carver, ME Welland, J Christodoulou, CM Dobson, S Meehan
Biophysical Journal
(2010)
98
(doi: 10.1016/j.bpj.2009.10.056)
Nanostructured films from hierarchical self-assembly of amyloidogenic proteins
TPJ Knowles, TW Oppenheim, AK Buell, DY Chirgadze, ME Welland
Nature Nanotechnology
(2010)
5
(doi: 10.1038/NNANO.2010.26)
Folding Study of Venus Reveals a Strong Ion Dependence of Its Yellow Fluorescence under Mildly Acidic Conditions
S-TD Hsu, G Blaser, C Behrens, LD Cabrita, CM Dobson, SE Jackson
J Biol Chem
(2010)
285
(doi: 10.1074/jbc.m109.000695)
Protein folding on the ribosome.
LD Cabrita, CM Dobson, J Christodoulou
Current Opinion in Structural Biology
(2010)
20
(doi: 10.1016/j.sbi.2010.01.005)
Detergent-like Interaction of Congo Red with the Amyloid β Peptide
C Lendel, B Bolognesi, A Wahlström, CM Dobson, A Gräslund
Biochemistry
(2010)
49
(doi: 10.1021/bi902005t)
Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy.
CR Bodner, AS Maltsev, CM Dobson, A Bax
Biochemistry
(2010)
49
(doi: 10.1021/bi901723p)
A causative link between the structure of aberrant protein oligomers and their toxicity
S Campioni, B Mannini, M Zampagni, A Pensalfini, C Parrini, E Evangelisti, A Relini, M Stefani, CM Dobson, C Cecchi, F Chiti
Nat Chem Biol
(2010)
6
(doi: 10.1038/nchembio.283)
Networks in Cell Biology
M Buchanan, G Caldarelli, P De Los Rios, F Rao, M Vendruscolo
(2010)
(doi: 10.1017/cbo9780511845086)
Methods and models in neurodegenerative and systemic protein aggregation diseases.
A-C Brorsson, JR Kumita, I MacLeod, B Bolognesi, E Speretta, LM Luheshi, TPJ Knowles, CM Dobson, DC Crowther
Front Biosci (Landmark Ed)
(2010)
15
(doi: 10.2741/3626)
Detecting and Characterizing Amyloid-β1-40 Oligomers using Single Molecule Fluorescence
P Narayan, A Orte, CM Dobson, D Klenerman
Biophysical Journal
(2010)
98
(doi: 10.1016/j.bpj.2009.12.3571)
The N-terminus of amyloid-beta plays a crucial role in its aggregation and toxicity
B Bolognesi, TR Jahn, AC Brorsson, LM Luheshi, JJ Yerbury, DC Crowther, CM Dobson
FEBS JOURNAL
(2010)
277
Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy.
LD Cabrita, S-TD Hsu, H Launay, CM Dobson, J Christodoulou
Proc Natl Acad Sci U S A
(2009)
106
(doi: 10.1073/pnas.0903750106)
An Analytical Solution to the Kinetics of Breakable Filament Assembly
TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, M Vendruscolo, EM Terentjev, ME Welland, CM Dobson
Science (New York, N.Y.)
(2009)
326
(doi: 10.1126/science.1178250)
Determination of the free energy landscape of α-synuclein using spin label nuclear magnetic resonance measurements
JR Allison, P Varnai, CM Dobson, M Vendruscolo
Journal of the American Chemical Society
(2009)
131
(doi: 10.1021/ja904716h)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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