Centre for Misfolding Diseases

Publications

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  • Currently displaying 1581 - 1600 of 2508 publications
Author(s)
Publication title
Journal Name
Publication year
Protein structure validation using side-chain chemical shifts.
AB Sahakyan, A Cavalli, WF Vranken, M Vendruscolo
Journal of Physical Chemistry B
(2012)
116
(doi: 10.1021/jp2122054)
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers.
E Evangelisti, C Cecchi, R Cascella, C Sgromo, M Becatti, CM Dobson, F Chiti, M Stefani
J Cell Sci
(2012)
125
(doi: 10.1242/jcs.098434)
Nanobodies as structural probes of protein misfolding and fibril formation
E De Genst, CM Dobson
Methods in Molecular Biology
(2012)
911
(doi: 10.1007/978-1-61779-968-6_34)
The nature and significance of protein aggregation phenomena
CM Dobson
PRION
(2012)
6
Selenenylsulfide-linked homogeneous glycopeptides and glycoproteins: synthesis of human "hepatic Se metabolite A".
O Boutureira, GJL Bernardes, M Fernández-González, DC Anthony, BG Davis
Angewandte Chemie (International ed. in English)
(2011)
51
(doi: 10.1002/anie.201106658)
A Traceless Vascular-Targeting Antibody–Drug Conjugate for Cancer Therapy
GJL Bernardes, G Casi, S Trüssel, I Hartmann, K Schwager, J Scheuermann, D Neri
Angewandte Chemie International Edition
(2011)
51
(doi: 10.1002/anie.201106527)
Hydrophobicity and conformational change as mechanistic determinants for nonspecific modulators of amyloid β self-assembly
A Abelein, B Bolognesi, CM Dobson, A Gräslund, C Lendel
Biochemistry
(2011)
51
(doi: 10.1021/bi201745g)
Experimental free energy surfaces reveal the mechanisms of maintenance of protein solubility.
A De Simone, A Dhulesia, G Soldi, M Vendruscolo, S-TD Hsu, F Chiti, CM Dobson
Proc Natl Acad Sci U S A
(2011)
108
(doi: 10.1073/pnas.1112197108)
Protein solubility and protein homeostasis: A generic view of protein misfolding disorders
M Vendruscolo, TPJ Knowles, CM Dobson
Cold Spring Harbor Perspectives in Biology
(2011)
3
(doi: 10.1101/cshperspect.a010454)
Clusterin facilitates in vivo clearance of extracellular misfolded proteins
AR Wyatt, JJ Yerbury, P Berghofer, I Greguric, A Katsifis, CM Dobson, MR Wilson
Cellular and Molecular Life Sciences
(2011)
68
(doi: 10.1007/s00018-011-0684-8)
Determination of Conformational Equilibria in Proteins Using Residual Dipolar Couplings
A De Simone, RW Montalvao, M Vendruscolo
Journal of Chemical Theory and Computation
(2011)
7
(doi: 10.1021/ct200361b)
Coarse-grained model for protein folding based on structural profiles.
K Wolff, M Vendruscolo, M Porto
Phys Rev E Stat Nonlin Soft Matter Phys
(2011)
84
(doi: 10.1103/PhysRevE.84.041934)
Introduction
M Buchanan, G Caldarelli, PDL Rios, F Rao, M Vendruscolo
(2011)
171
(doi: 10.1017/CBO9780511845086.001)
Probing small molecule binding to amyloid fibrils
AK Buell, EK Esbjörner, PJ Riss, DA White, FI Aigbirhio, G Toth, ME Welland, CM Dobson, TPJ Knowles
Phys Chem Chem Phys
(2011)
13
(doi: 10.1039/c1cp22283j)
Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation.
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
PLOS Computational Biology
(2011)
7
(doi: 10.1371/journal.pcbi.1002169)
Binding of the Molecular Chaperone αB-Crystallin to Aβ Amyloid Fibrils Inhibits Fibril Elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
Biophysical journal
(2011)
101
(doi: 10.1016/j.bpj.2011.07.056)
Using side-chain aromatic proton chemical shifts for a quantitative analysis of protein structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie International Edition
(2011)
50
(doi: 10.1002/anie.201101641)
Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster
JR Kumita, L Helmfors, J Williams, LM Luheshi, L Menzer, M Dumoulin, DA Lomas, DC Crowther, CM Dobson, A-C Brorsson
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
(2011)
26
(doi: 10.1096/fj.11-185983)
ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism
T Murakami, S-P Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, J Robertson, H Suzuki, GG Tartaglia, M Vendruscolo, GS Kaminski Schierle, FTS Chan, A Moloney, D Crowther, CF Kaminski, M Zhen, P St George-Hyslop
Hum Mol Genet
(2011)
21
(doi: 10.1093/hmg/ddr417)
Excited-state control of protein activity
M Vendruscolo
Journal of Molecular Biology
(2011)
412
(doi: 10.1016/j.jmb.2011.07.047)
Yusuf Hamied Department of Chemistry
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