Centre for Misfolding Diseases

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  • Currently displaying 1621 - 1640 of 2523 publications
Author(s)
Publication title
Journal Name
Publication year
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608917)
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
Journal of Molecular Biology
(2011)
411
(doi: 10.1016/j.jmb.2011.05.046)
Intermolecular structure determination of amyloid fibrils with magic-angle spinning and dynamic nuclear polarization NMR.
MJ Bayro, GT Debelouchina, MT Eddy, NR Birkett, CE MacPhee, M Rosay, WE Maas, CM Dobson, RG Griffin
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja203756x)
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments.
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608916)
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
J Chem Phys
(2011)
135
(doi: 10.1063/1.3608918)
Direct radiolabelling of proteins at cysteine using [ 18 F]-fluorosugars
O Boutureira, GJL Bernardes, F D'Hooge, BG Davis
Chem Commun (Camb)
(2011)
47
(doi: 10.1039/c1cc13524d)
The A53T mutation is key in defining the differences in the aggregation kinetics of human and mouse α-synuclein.
L Kang, K-P Wu, M Vendruscolo, J Baum
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja203979j)
Methods for converting cysteine to dehydroalanine on peptides and proteins
JM Chalker, SB Gunnoo, O Boutureira, SC Gerstberger, M Fernández-González, GJL Bernardes, L Griffin, H Hailu, CJ Schofield, BG Davis
Chemical Science
(2011)
2
(doi: 10.1039/c1sc00185j)
In situ measurements of the formation and morphology of intracellular β-amyloid fibrils by super-resolution fluorescence imaging.
GS Kaminski Schierle, S van de Linde, M Erdelyi, EK Esbjörner, T Klein, E Rees, CW Bertoncini, CM Dobson, M Sauer, CF Kaminski
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja201651w)
Kinetics of protein aggregation
T Knowles, M Vendruscolo, C Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Structure-based prediction of methyl chemical shifts in proteins
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Journal of Biomolecular NMR
(2011)
50
(doi: 10.1007/s10858-011-9524-2)
Characterizing the amyloidogenic state of the acylphosphatase from Sulfolobus solfataricus
F Bemporad, A De Simone, F Chiti, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Insights into the molecular mechanisms of Hsp70-mediated inhibition of amyloid formation
FA Aprile, A Dhulesia, F Stengel, T Eliseo, C Roodvelt, B Bolognesi, P Tortora, X Salvatella, N Cremades, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Direct observation of the interconversion of normal and pathogenic forms of alpha-synuclein
N Cremades, SIA Cohen, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, TPJ Knowles, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Towards Improved Therapeutic CORMs: Understanding the Reactivity of CORM-3 with Proteins
T Santos-Silva, A Mukhopadhyay, JD Seixas, GJL Bernardes, CC Romão, MJ Romão
Current Medicinal Chemistry
(2011)
18
(doi: 10.2174/092986711796504583)
Nanomechanics of functional and pathological amyloid materials
TPJ Knowles, MJ Buehler
Nature Nanotechnology
(2011)
6
(doi: 10.1038/nnano.2011.102)
Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris.
G Whyteside, MJC Alcocer, JR Kumita, CM Dobson, M Lazarou, RJ Pleass, DB Archer
Plos One
(2011)
6
(doi: 10.1371/journal.pone.0022692)
Using chemical shifts to determine structural changes in proteins upon complex formation
A Cavalli, RW Montalvao, M Vendruscolo
J Phys Chem B
(2011)
115
(doi: 10.1021/jp202647q)
Nucleated polymerisation in the presence of pre-formed seed filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
(2011)
(doi: 10.48550/arxiv.1107.1454)
The iFly tracking system for an automated locomotor and behavioural analysis of Drosophila melanogaster
KJ Kohlhoff, TR Jahn, DA Lomas, CM Dobson, DC Crowther, M Vendruscolo
Integrative Biology
(2011)
3
(doi: 10.1039/c0ib00149j)
Yusuf Hamied Department of Chemistry
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