Centre for Misfolding Diseases

Publications

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  • Currently displaying 1481 - 1500 of 2401 publications
Author(s)
Publication title
Journal Name
Publication year
Protein solubility and protein homeostasis: A generic view of protein misfolding disorders
M Vendruscolo, TPJ Knowles, CM Dobson
Cold Spring Harbor Perspectives in Biology
(2011)
3
(doi: 10.1101/cshperspect.a010454)
Clusterin facilitates in vivo clearance of extracellular misfolded proteins
AR Wyatt, JJ Yerbury, P Berghofer, I Greguric, A Katsifis, CM Dobson, MR Wilson
Cellular and Molecular Life Sciences
(2011)
68
(doi: 10.1007/s00018-011-0684-8)
Determination of Conformational Equilibria in Proteins Using Residual Dipolar Couplings
A De Simone, RW Montalvao, M Vendruscolo
Journal of chemical theory and computation
(2011)
7
(doi: 10.1021/ct200361b)
Coarse-grained model for protein folding based on structural profiles.
K Wolff, M Vendruscolo, M Porto
Phys Rev E Stat Nonlin Soft Matter Phys
(2011)
84
(doi: 10.1103/physreve.84.041934)
Introduction
M Buchanan, G Caldarelli, PDL Rios, F Rao, M Vendruscolo
(2011)
171
(doi: 10.1017/CBO9780511845086.001)
Probing small molecule binding to amyloid fibrils
AK Buell, EK Esbjörner, PJ Riss, DA White, FI Aigbirhio, G Toth, ME Welland, CM Dobson, TPJ Knowles
Phys Chem Chem Phys
(2011)
13
(doi: 10.1039/c1cp22283j)
Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
PLoS Comput. Biol.
(2011)
7
(doi: 10.1371/journal.pcbi.1002169)
Binding of the molecular chaperone αb-crystallin to Aβ amyloid fibrils inhibits fibril elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
Biophysical journal
(2011)
101
(doi: 10.1016/j.bpj.2011.07.056)
Using side-chain aromatic proton chemical shifts for a quantitative analysis of protein structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie International Edition
(2011)
50
(doi: 10.1002/anie.201101641)
Disease‐related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster
JR Kumita, L Helmfors, J Williams, LM Luheshi, L Menzer, M Dumoulin, DA Lomas, DC Crowther, CM Dobson, A-C Brorsson
The FASEB Journal
(2011)
26
(doi: 10.1096/fj.11-185983)
Als mutations in FUS cause neuronal dysfunction and death in caenorhabditis elegans by a dominant gain-of-function mechanism
T Murakami, S-P Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, J Robertson, H Suzuki, GG Tartaglia, M Vendruscolo, GS Kaminski Schierle, FTS Chan, A Moloney, D Crowther, CF Kaminski, M Zhen, P St George-Hyslop
Human molecular genetics
(2011)
21
(doi: 10.1093/hmg/ddr417)
Excited-state control of protein activity
M Vendruscolo
Journal of Molecular Biology
(2011)
412
(doi: 10.1016/j.jmb.2011.07.047)
Nucleated polymerisation in the presence of pre-formed seed filaments.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
International journal of molecular sciences
(2011)
12
(doi: 10.3390/ijms12095844)
Using Side‐Chain Aromatic Proton Chemical Shifts for a Quantitative Analysis of Protein Structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie
(2011)
123
(doi: 10.1002/ange.201101641)
On the effect of Trigger Factor on nascent chain protein folding off of the ribosome
EP O'Brien, M Vendruscolo, CM Dobson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2011)
242
Observation of spatial propagation of amyloid assembly from single nuclei
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
Proceedings of the National Academy of Sciences
(2011)
108
(doi: 10.1073/pnas.1105555108)
Metastability of native proteins and the phenomenon of amyloid formation.
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja2017703)
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
Journal of Molecular Biology
(2011)
411
(doi: 10.1016/j.jmb.2011.05.046)
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608916)
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608917)
Yusuf Hamied Department of Chemistry
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