Centre for Misfolding Diseases

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  • Currently displaying 1481 - 1500 of 2523 publications
Author(s)
Publication title
Journal Name
Publication year
Single-Molecule Characterisation of Alpha-Synuclein Oligomers
MH Horrocks, SF Lee, S Gandhi, M Iljina, L Tosatto, CM Dobson, D Klenerman
BIOPHYSICAL JOURNAL
(2014)
106
Determination of the individual roles of the linker residues in the interdomain motions of calmodulin using NMR chemical shifts
P Kukic, C Camilloni, A Cavalli, M Vendruscolo
Biophysical Journal
(2014)
106
(doi: 10.1016/j.jmb.2014.02.002)
Insights into the Inhibition Mechanism of Biomolecular Self-Assembly from Chemical Kinetics
P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.3776)
A simple lattice model that captures protein folding, aggregation and amyloid formation
S Abeln, M Vendruscolo, CM Dobson, D Frenkel
Plos One
(2014)
9
(doi: 10.1371/journal.pone.0085185)
Rationally designed short polyisoprenol-linked PglB substrates for engineered polypeptide and protein N-glycosylation
F Liu, B Vijayakrishnan, A Faridmoayer, TA Taylor, TB Parsons, GJL Bernardes, M Kowarik, BG Davis
Journal of the American Chemical Society
(2014)
136
(doi: 10.1021/ja409409h)
Kinetic modelling indicates that fast-translating codons can coordinate cotranslational protein folding by avoiding misfolded intermediates
EP O'Brien, M Vendruscolo, CM Dobson
Nature communications
(2014)
5
(doi: 10.1038/ncomms3988)
Sonochemically-induced spectral shift as a probe of green fluorescent protein release from nano capsules
U Shimanovich, A Munder, NG Azoia, A Cavaco-Paulo, A Gruzman, TPJ Knowles, A Gedanken
RSC Adv.
(2014)
4
(doi: 10.1039/c3ra47915c)
Chapter 41 Structure of a Misfolded Intermediate of a PDZ Domain
A De Simone, S Gianni, M Vendruscolo
(2014)
(doi: 10.1016/b978-0-12-394431-3.00041-9)
Nanoscale spatially resolved infrared spectra from single microdroplets.
T Müller, FS Ruggeri, AJ Kulik, U Shimanovich, TO Mason, TPJ Knowles, G Dietler
Lab on a chip
(2014)
14
(doi: 10.1039/c3lc51219c)
Chemical kinetics for drug discovery to combat protein aggregation diseases
P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Trends in Pharmacological Sciences
(2014)
35
Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation
FA Aprile, G Meisl, AK Buell, P Flagmeier, CM Dobson, M Vendruscolo, TPJ Knowles
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.1570)
A Clear View of Polymorphism, Twist, and Chirality in Amyloid Fibril Formation
LR Volpatti, M Vendruscolo, CM Dobson, TPJ Knowles
ACS nano
(2013)
7
(doi: 10.1021/nn406121w)
Quantification of the Concentration of Aβ42 Propagons during the Lag Phase by an Amyloid Chain Reaction Assay
P Arosio, R Cukalevski, B Frohm, TPJ Knowles, S Linse
Journal of the American Chemical Society
(2013)
136
(doi: 10.1021/ja408765u)
Higher Order Amyloid Fibril Structure by MAS NMR and DNP Spectroscopy
GT Debelouchina, MJ Bayro, AW Fitzpatrick, V Ladizhansky, MT Colvin, MA Caporini, CP Jaroniec, VS Bajaj, M Rosay, CE Macphee, M Vendruscolo, WE Maas, CM Dobson, RG Griffin
J Am Chem Soc
(2013)
135
(doi: 10.1021/ja409050a)
Protein micro- and nano-capsules for biomedical applications
U Shimanovich, GJL Bernardes, TPJ Knowles, A Cavaco-Paulo
Chem. Soc. Rev.
(2013)
43
(doi: 10.1039/c3cs60376h)
Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy.
D Pinotsi, AK Buell, C Galvagnion, CM Dobson, GS Kaminski Schierle, CF Kaminski
Nano letters
(2013)
14
(doi: 10.1021/nl4041093)
Polymer physics inspired approaches for the study of the mechanical properties of amyloid fibrils
LR Volpatti, TPJ Knowles
Journal of Polymer Science Part B Polymer Physics
(2013)
52
(doi: 10.1002/polb.23428)
Replica-Averaged Metadynamics.
C Camilloni, A Cavalli, M Vendruscolo
Journal of chemical theory and computation
(2013)
9
(doi: 10.1021/ct4006272)
Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
C Roodveldt, A Labrador-Garrido, E Gonzalez-Rey, CC Lachaud, T Guilliams, R Fernandez-Montesinos, A Benitez-Rondan, G Robledo, A Hmadcha, M Delgado, CM Dobson, D Pozo
PLoS One
(2013)
8
(doi: 10.1371/journal.pone.0079160)
Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins.
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo
Cell Rep
(2013)
5
(doi: 10.1016/j.celrep.2013.09.043)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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