Centre for Misfolding Diseases

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  • Currently displaying 1441 - 1460 of 2474 publications
Author(s)
Publication title
Journal Name
Publication year
Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation
FA Aprile, G Meisl, AK Buell, P Flagmeier, CM Dobson, M Vendruscolo, TPJ Knowles
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.1570)
Chemical kinetics for drug discovery to combat protein aggregation diseases
P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Trends in Pharmacological Sciences
(2014)
35
Chapter 41 Structure of a Misfolded Intermediate of a PDZ Domain
A De Simone, S Gianni, M Vendruscolo
(2014)
(doi: 10.1016/b978-0-12-394431-3.00041-9)
Sonochemically-induced spectral shift as a probe of green fluorescent protein release from nano capsules
U Shimanovich, A Munder, NG Azoia, A Cavaco-Paulo, A Gruzman, TPJ Knowles, A Gedanken
Rsc Advances
(2014)
4
(doi: 10.1039/c3ra47915c)
A clear view of polymorphism, twist, and chirality in amyloid fibril formation.
LR Volpatti, M Vendruscolo, CM Dobson, TPJ Knowles
ACS Nano
(2013)
7
(doi: 10.1021/nn406121w)
Quantification of the concentration of Aβ42 propagons during the lag phase by an amyloid chain reaction assay.
P Arosio, R Cukalevski, B Frohm, TPJ Knowles, S Linse
Journal of the American Chemical Society
(2013)
136
(doi: 10.1021/ja408765u)
Higher order amyloid fibril structure by MAS NMR and DNP spectroscopy.
GT Debelouchina, MJ Bayro, AW Fitzpatrick, V Ladizhansky, MT Colvin, MA Caporini, CP Jaroniec, VS Bajaj, M Rosay, CE Macphee, M Vendruscolo, WE Maas, CM Dobson, RG Griffin
J Am Chem Soc
(2013)
135
(doi: 10.1021/ja409050a)
Protein micro- and nano-capsules for biomedical applications.
U Shimanovich, GJL Bernardes, TPJ Knowles, A Cavaco-Paulo
Chem Soc Rev
(2013)
43
(doi: 10.1039/c3cs60376h)
Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy
D Pinotsi, AK Buell, C Galvagnion, CM Dobson, GS Kaminski Schierle, CF Kaminski
Nano letters
(2013)
14
(doi: 10.1021/nl4041093)
Polymer physics inspired approaches for the study of the mechanical properties of amyloid fibrils
LR Volpatti, TPJ Knowles
Journal of Polymer Science Part B Polymer Physics
(2013)
52
(doi: 10.1002/polb.23428)
Replica-Averaged Metadynamics.
C Camilloni, A Cavalli, M Vendruscolo
J Chem Theory Comput
(2013)
9
(doi: 10.1021/ct4006272)
Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.
C Roodveldt, A Labrador-Garrido, E Gonzalez-Rey, CC Lachaud, T Guilliams, R Fernandez-Montesinos, A Benitez-Rondan, G Robledo, A Hmadcha, M Delgado, CM Dobson, D Pozo
PloS one
(2013)
8
(doi: 10.1371/journal.pone.0079160)
Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo
Cell Rep
(2013)
5
(doi: 10.1016/j.celrep.2013.09.043)
pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins.
M Varadi, S Kosol, P Lebrun, E Valentini, M Blackledge, AK Dunker, IC Felli, JD Forman-Kay, RW Kriwacki, R Pierattelli, J Sussman, DI Svergun, VN Uversky, M Vendruscolo, D Wishart, PE Wright, P Tompa
Nucleic acids research
(2013)
42
(doi: 10.1093/nar/gkt960)
Highlights from the 48th EUCHEM conference on stereochemistry, Burgenstock, Switzerland, May 2013
GJL Bernardes
Chemical Communications
(2013)
49
(doi: 10.1039/c3cc90259e)
Site-specific chemical modification of antibody fragments using traceless cleavable linkers.
GJL Bernardes, M Steiner, I Hartmann, D Neri, G Casi
Nat Protoc
(2013)
8
(doi: 10.1038/nprot.2013.121)
A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation
E De Genst, P-H Chan, E Pardon, S-TD Hsu, JR Kumita, J Christodoulou, L Menzer, DY Chirgadze, CV Robinson, S Muyldermans, A Matagne, L Wyns, CM Dobson, M Dumoulin
The Journal of Physical Chemistry B
(2013)
117
(doi: 10.1021/jp403425z)
Cucurbit[8]uril and Blue-Box: High-Energy Water Release Overwhelms Electrostatic Interactions
F Biedermann, M Vendruscolo, OA Scherman, A De Simone, WM Nau
J Am Chem Soc
(2013)
135
(doi: 10.1021/ja407951x)
Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase
A Pica, A Merlino, AK Buell, TPJ Knowles, E Pizzo, G D'Alessio, F Sica, L Mazzarella
Acta crystallographica. Section D, Biological crystallography
(2013)
69
(doi: 10.1107/s0907444913020507)
Subdomain Architecture and Stability of a Giant Repeat Protein
M Tsytlonok, P Sormanni, PJE Rowling, M Vendruscolo, LS Itzhaki
The journal of physical chemistry. B
(2013)
117
(doi: 10.1021/jp402360x)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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