Centre for Misfolding Diseases

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  • Currently displaying 1441 - 1460 of 2401 publications
Author(s)
Publication title
Journal Name
Publication year
Fucose-specific conjugation of hydrazide derivatives to a vascular-targeting monoclonal antibody in IgG format.
K Zuberbühler, G Casi, GJL Bernardes, D Neri
Chemical communications (Cambridge, England)
(2012)
48
(doi: 10.1039/c2cc32412a)
Selenium-enhanced electron microscopic imaging of different aggregate forms of a segment of the amyloid β peptide in cells.
EK McGuire, M Motskin, B Bolognesi, SD Bergin, TPJ Knowles, J Skepper, LM Luheshi, DW McComb, CM Dobson, AE Porter
ACS nano
(2012)
6
(doi: 10.1021/nn204859e)
Characterizing intermolecular interactions that initiate native-like protein aggregation
F Bemporad, A De Simone, F Chiti, CM Dobson
Biophysical Journal
(2012)
102
(doi: 10.1016/j.bpj.2012.03.057)
Prediction of variable translation rate effects on cotranslational protein folding
EP O'Brien, M Vendruscolo, CM Dobson
Nature Communications
(2012)
3
(doi: 10.1038/ncomms1850)
Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
N Cremades, SIA Cohen, E Deas, AY Abramov, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, NW Wood, TPJ Knowles, CM Dobson, D Klenerman
Cell
(2012)
149
(doi: 10.1016/j.cell.2012.03.037)
Role of Elongation and Secondary Pathways in S6 Amyloid Fibril Growth
N Lorenzen, SIA Cohen, SB Nielsen, TW Herling, G Christiansen, CM Dobson, TPJ Knowles, D Otzen
Biophys J
(2012)
102
(doi: 10.1016/j.bpj.2012.03.047)
Fibrillogenic propensity of the GroEL apical domain: A Janus-faced minichaperone
J Chen, H Yagi, P Sormanni, M Vendruscolo, K Makabe, T Nakamura, Y Goto, K Kuwajima
FEBS Letters
(2012)
586
(doi: 10.1016/j.febslet.2012.03.019)
Structure of an intermediate state in protein folding and aggregation
P Neudecker, P Robustelli, A Cavalli, P Walsh, P Lundström, A Zarrine-Afsar, S Sharpe, M Vendruscolo, LE Kay
Science (New York, N.Y.)
(2012)
336
(doi: 10.1126/science.1214203)
Intrinsic disorder modulates protein self-assembly and aggregation.
A De Simone, C Kitchen, AH Kwan, M Sunde, CM Dobson, D Frenkel
Proceedings of the National Academy of Sciences of the United States of America
(2012)
109
(doi: 10.1073/pnas.1118048109)
Analyse der Energiebarrieren für das Wachstum von Amyloidfibrillen
AK Buell, A Dhulesia, DA White, TPJ Knowles, CM Dobson, ME Welland
Angewandte Chemie
(2012)
124
(doi: 10.1002/ange.201108040)
Detailed Analysis of the Energy Barriers for Amyloid Fibril Growth
AK Buell, A Dhulesia, DA White, TPJ Knowles, CM Dobson, ME Welland
Angew Chem Int Ed Engl
(2012)
51
(doi: 10.1002/anie.201108040)
1H, 13C and 15N resonance assignments of human muscle acylphosphatase
G Fusco, A De Simone, STD Hsu, F Bemporad, M Vendruscolo, F Chiti, CM Dobson
Biomolecular NMR Assignments
(2012)
6
(doi: 10.1007/s12104-011-9318-1)
Proteome folding and aggregation
M Vendruscolo
Current Opinion in Structural Biology
(2012)
22
(doi: 10.1016/j.sbi.2012.01.005)
Expression in Drosophila of Tandem Amyloid β Peptides Provides Insights into Links between Aggregation and Neurotoxicity*
E Speretta, TR Jahn, GG Tartaglia, G Favrin, TP Barros, S Imarisio, DA Lomas, LM Luheshi, DC Crowther, CM Dobson
Journal of Biological Chemistry
(2012)
287
(doi: 10.1074/jbc.m112.350124)
Determination of Secondary Structure Populations in Disordered States of Proteins Using Nuclear Magnetic Resonance Chemical Shifts
C Camilloni, A De Simone, WF Vranken, M Vendruscolo
Biochemistry
(2012)
51
(doi: 10.1021/bi3001825)
A Novel Carbon Monoxide-Releasing Molecule Fully Protects Mice from Severe Malaria
AC Pena, N Penacho, L Mancio-Silva, R Neres, JD Seixas, AC Fernandes, CC Romão, MM Mota, GJL Bernardes, A Pamplona
Antimicrobial agents and chemotherapy
(2012)
56
(doi: 10.1128/AAC.05571-11)
The Aggregation and Neurotoxicity of TDP-43 and Its ALS-Associated 25 kDa Fragment Are Differentially Affected by Molecular Chaperones in Drosophila
JM Gregory, TP Barros, S Meehan, CM Dobson, LM Luheshi
PLoS ONE
(2012)
7
(doi: 10.1371/journal.pone.0031899)
Characterization of the conformational equilibrium between the two major substates of RNase A using NMR chemical shifts.
C Camilloni, P Robustelli, A De Simone, A Cavalli, M Vendruscolo
Journal of the American Chemical Society
(2012)
134
(doi: 10.1021/ja210951z)
Developing drug molecules for therapy with carbon monoxide.
CC Romão, WA Blättler, JD Seixas, GJL Bernardes
Chemical Society reviews
(2012)
41
(doi: 10.1039/c2cs15317c)
Blind testing of routine, fully automated determination of protein structures from nmr data
A Rosato, JM Aramini, C Arrowsmith, A Bagaria, D Baker, A Cavalli, JF Doreleijers, A Eletsky, A Giachetti, P Guerry, A Gutmanas, P Güntert, Y He, T Herrmann, YJ Huang, V Jaravine, HRA Jonker, MA Kennedy, OF Lange, G Liu, TE Malliavin, R Mani, B Mao, GT Montelione, M Nilges, P Rossi, G Van Der Schot, H Schwalbe, TA Szyperski, M Vendruscolo, R Vernon, WF Vranken, S De Vries, GW Vuister, B Wu, Y Yang, AMJJ Bonvin
Structure
(2012)
20
(doi: 10.1016/j.str.2012.01.002)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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