Centre for Misfolding Diseases

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  • Currently displaying 1401 - 1420 of 2338 publications
Author(s)
Publication title
Journal Name
Publication year
Binding of the Molecular Chaperone αB-Crystallin to Aβ Amyloid Fibrils Inhibits Fibril Elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
Biophysical Journal
(2011)
101
(doi: 10.1016/j.bpj.2011.07.056)
Using Side-Chain Aromatic Proton Chemical Shifts for a Quantitative Analysis of Protein Structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie (International ed. in English)
(2011)
50
(doi: 10.1002/anie.201101641)
Using side-chain aromatic proton chemical shifts for a quantitative analysis of protein structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie International Edition
(2011)
50
(doi: 10.1002/anie.201101641)
Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster.
JR Kumita, L Helmfors, J Williams, LM Luheshi, L Menzer, M Dumoulin, DA Lomas, DC Crowther, CM Dobson, A-C Brorsson
FASEB Journal
(2011)
26
(doi: 10.1096/fj.11-185983)
ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism.
T Murakami, S-P Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, J Robertson, H Suzuki, GG Tartaglia, M Vendruscolo, GS Kaminski Schierle, FTS Chan, A Moloney, D Crowther, CF Kaminski, M Zhen, P St George-Hyslop
Human Molecular Genetics
(2011)
21
(doi: 10.1093/hmg/ddr417)
Excited-state control of protein activity
M Vendruscolo
Journal of Molecular Biology
(2011)
412
(doi: 10.1016/j.jmb.2011.07.047)
Nucleated polymerisation in the presence of pre-formed seed filaments.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
Int J Mol Sci
(2011)
12
(doi: 10.3390/ijms12095844)
Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
International Journal of Molecular Sciences
(2011)
12
(doi: 10.3390/ijms12095844)
Using Side‐Chain Aromatic Proton Chemical Shifts for a Quantitative Analysis of Protein Structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie
(2011)
123
(doi: 10.1002/ange.201101641)
On the effect of Trigger Factor on nascent chain protein folding off of the ribosome
EP O'Brien, M Vendruscolo, CM Dobson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2011)
242
Observation of spatial propagation of amyloid assembly from single nuclei
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
Proceedings of the National Academy of Sciences of the United States of America
(2011)
108
(doi: 10.1073/pnas.1105555108)
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
Journal of the American Chemical Society
(2011)
133
(doi: 10.1021/ja2017703)
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments.
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608916)
Intermolecular structure determination of amyloid fibrils with magic-angle spinning and dynamic nuclear polarization NMR.
MJ Bayro, GT Debelouchina, MT Eddy, NR Birkett, CE MacPhee, M Rosay, WE Maas, CM Dobson, RG Griffin
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja203756x)
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
Journal of Molecular Biology
(2011)
411
(doi: 10.1016/j.jmb.2011.05.046)
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608918)
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608917)
Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars.
O Boutureira, GJL Bernardes, F D'Hooge, BG Davis
Chem Commun (Camb)
(2011)
47
(doi: 10.1039/c1cc13524d)
Protein Solubility and Protein Homeostasis: A Generic View of Protein Misfolding Disorders
M Vendruscolo, TPJ Knowles, CM Dobson
Cold Spring Harb Perspect Biol
(2011)
3
(doi: 10.1101/cshperspect.a010454)
The A53T Mutation is Key in Defining the Differences in the Aggregation Kinetics of Human and Mouse alpha-Synuclein
L Kang, K-P Wu, M Vendruscolo, J Baum
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja203979j)
Yusuf Hamied Department of Chemistry
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