Centre for Misfolding Diseases

Publications

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  • Currently displaying 1401 - 1420 of 2508 publications
Author(s)
Publication title
Journal Name
Publication year
Single‐Molecule Imaging Reveals that Small Amyloid‐β1–42 Oligomers Interact with the Cellular Prion Protein (PrPC)
KA Ganzinger, P Narayan, SS Qamar, L Weimann, RT Ranasinghe, A Aguzzi, CM Dobson, J McColl, P St George-Hyslop, D Klenerman
Chembiochem
(2014)
15
(doi: 10.1002/cbic.201402377)
Cysteine-selective reactions for antibody conjugation
PMSD Cal, GJL Bernardes, PMP Gois
Angewandte Chemie International Edition
(2014)
53
(doi: 10.1002/anie.201405702)
Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein.
S Gianni, C Camilloni, R Giri, A Toto, D Bonetti, A Morrone, P Sormanni, M Brunori, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1405233111)
Interaction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (Aβ42) aggregates leads to sub-stoichiometric inhibition of amyloid formation.
C Månsson, P Arosio, R Hussein, HH Kampinga, RM Hashem, WC Boelens, CM Dobson, TPJ Knowles, S Linse, C Emanuelsson
J Biol Chem
(2014)
289
(doi: 10.1074/jbc.M114.595124)
Identification and characterization of PKCPγ, a kinase associated with SCA14, as an amyloidogenic protein
H Takahashi, N Adachi, T Shirafuji, S Danno, T Ueyama, M Vendruscolo, AN Shuvaev, T Sugimoto, T Seki, D Hamada, K Irie, H Hirai, N Sakai, N Saito
Hum Mol Genet
(2014)
24
(doi: 10.1093/hmg/ddu472)
Equilibrium simulations of proteins using molecular fragment replacement and NMR chemical shifts.
W Boomsma, P Tian, J Frellsen, J Ferkinghoff-Borg, T Hamelryck, K Lindorff-Larsen, M Vendruscolo
Proceedings of the National Academy of Sciences
(2014)
111
(doi: 10.1073/pnas.1404948111)
NMR characterization of the conformational fluctuations of the human lymphocyte function‐associated antigen‐1 I‐domain
HTA Leung, P Kukic, C Camilloni, F Bemporad, A De Simone, FA Aprile, JR Kumita, M Vendruscolo
Protein Science
(2014)
23
(doi: 10.1002/pro.2538)
Antibodies and protein misfolding: From structural research tools to therapeutic strategies
E De Genst, A Messer, CM Dobson
Biochimica et biophysica acta
(2014)
1844
(doi: 10.1016/j.bbapap.2014.08.016)
The physical chemistry of the amyloid phenomenon: thermodynamics and kinetics of filamentous protein aggregation.
AK Buell, CM Dobson, TPJ Knowles
Essays in Biochemistry
(2014)
56
(doi: 10.1042/BSE0560011)
Highlights from the 49th EUCHEM Conference on Stereochemistry, Burgenstock, Switzerland, May 2014
GJL Bernardes, AL Lawrence
Chemical Communications
(2014)
50
(doi: 10.1039/c4cc90250e)
Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity
B Mannini, E Mulvihill, C Sgromo, R Cascella, R Khodarahmi, M Ramazzotti, CM Dobson, C Cecchi, F Chiti
ACS Chemical Biology
(2014)
9
(doi: 10.1021/cb500505m)
Archaeal MBF1 binds to 30S and 70S ribosomes via its helix–turn–helix domain
F Blombach, H Launay, APL Snijders, V Zorraquino, H Wu, B de Koning, SJJ Brouns, TJG Ettema, C Camilloni, A Cavalli, M Vendruscolo, MJ Dickman, LD Cabrita, A La Teana, D Benelli, P Londei, J Christodoulou, J van der Oost
Biochem J
(2014)
462
(doi: 10.1042/BJ20131474)
Carbon-monoxide-releasing molecules for the delivery of therapeutic co in vivo
S García-Gallego, GJL Bernardes
Angewandte Chemie (International ed. in English)
(2014)
53
(doi: 10.1002/anie.201311225)
Easyworm: an open-source software tool to determine the mechanical properties of worm-like chains
G Lamour, JB Kirkegaard, H Li, TP Knowles, J Gsponer
Source Code for Biology and Medicine
(2014)
9
(doi: 10.1186/1751-0473-9-16)
Amyloid Beta Peptide Aβ40 and Aβ42 Form Separate Fibrils in Binary Mixtures
X Yang, R Cukalevski, G Meisl, B Frohm, T Knowles, S Linse
PROTEIN SCIENCE
(2014)
23
Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism.
C Camilloni, AB Sahakyan, MJ Holliday, NG Isern, F Zhang, EZ Eisenmesser, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1404220111)
Statistical Mechanics of the Denatured State of a Protein Using Replica-Averaged Metadynamics
C Camilloni, M Vendruscolo
J Am Chem Soc
(2014)
136
(doi: 10.1021/ja5027584)
Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides
G Meisl, X Yang, E Hellstrand, B Frohm, JB Kirkegaard, SIA Cohen, CM Dobson, S Linse, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1401564111)
The amyloid state and its association with protein misfolding diseases (vol 15, pg 384, 2014)
TPJ Knowles, M Vendruscolo, CM Dobson
Nature Reviews Molecular Cell Biology
(2014)
15
(doi: 10.1038/nrm3826)
A tensor-free method for the structural and dynamical refinement of proteins using residual dipolar couplings
C Camilloni, M Vendruscolo
J Phys Chem B
(2014)
119
(doi: 10.1021/jp5021824)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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