Centre for Misfolding Diseases

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  • Currently displaying 1381 - 1400 of 2455 publications
Author(s)
Publication title
Journal Name
Publication year
Chapter 41 Structure of a Misfolded Intermediate of a PDZ Domain
A De Simone, S Gianni, M Vendruscolo
(2014)
(doi: 10.1016/b978-0-12-394431-3.00041-9)
Rationally Designed Short Polyisoprenol-Linked PglB Substrates for Engineered Polypeptide and Protein N-Glycosylation
F Liu, B Vijayakrishnan, A Faridmoayer, TA Taylor, TB Parsons, GJL Bernardes, M Kowarik, BG Davis
J Am Chem Soc
(2013)
136
(doi: 10.1021/ja409409h)
A clear view of polymorphism, twist, and chirality in amyloid fibril formation.
LR Volpatti, M Vendruscolo, CM Dobson, TPJ Knowles
ACS Nano
(2013)
7
(doi: 10.1021/nn406121w)
Quantification of the Concentration of Aβ42 Propagons during the Lag Phase by an Amyloid Chain Reaction Assay
P Arosio, R Cukalevski, B Frohm, TPJ Knowles, S Linse
J Am Chem Soc
(2013)
136
(doi: 10.1021/ja408765u)
Higher Order Amyloid Fibril Structure by MAS NMR and DNP Spectroscopy
GT Debelouchina, MJ Bayro, AW Fitzpatrick, V Ladizhansky, MT Colvin, MA Caporini, CP Jaroniec, VS Bajaj, M Rosay, CE Macphee, M Vendruscolo, WE Maas, CM Dobson, RG Griffin
J Am Chem Soc
(2013)
135
(doi: 10.1021/ja409050a)
Protein micro- and nano-capsules for biomedical applications
U Shimanovich, GJL Bernardes, TPJ Knowles, A Cavaco-Paulo
Chem. Soc. Rev.
(2013)
43
(doi: 10.1039/c3cs60376h)
Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy
D Pinotsi, AK Buell, C Galvagnion, CM Dobson, GS Kaminski Schierle, CF Kaminski
Nano letters
(2013)
14
(doi: 10.1021/nl4041093)
Polymer Physics Inspired Approaches for the Study of the Mechanical Properties of Amyloid Fibrils
LR Volpatti, TPJ Knowles
Journal of Polymer Science Part B Polymer Physics
(2013)
52
(doi: 10.1002/polb.23428)
Single Point Mutations Induce a Switch in the Molecular Mechanism of the Aggregation of the Alzheimer's Disease Associated Aβ42 Peptide
B Bolognesi, SIA Cohen, P Aran Terol, EK Esbjörner, S Giorgetti, MF Mossuto, A Natalello, A-C Brorsson, TPJ Knowles, CM Dobson, LM Luheshi
ACS Chemical Biology
(2013)
9
(doi: 10.1021/cb400616y)
Replica-Averaged Metadynamics
C Camilloni, A Cavalli, M Vendruscolo
Journal of chemical theory and computation
(2013)
9
(doi: 10.1021/ct4006272)
Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
C Roodveldt, A Labrador-Garrido, E Gonzalez-Rey, CC Lachaud, T Guilliams, R Fernandez-Montesinos, A Benitez-Rondan, G Robledo, A Hmadcha, M Delgado, CM Dobson, D Pozo
PLoS ONE
(2013)
8
(doi: 10.1371/journal.pone.0079160)
Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins.
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo
Cell Rep
(2013)
5
(doi: 10.1016/j.celrep.2013.09.043)
PE-DB: A database of structural ensembles of intrinsically disordered and of unfolded proteins
M Varadi, S Kosol, P Lebrun, E Valentini, M Blackledge, AK Dunker, IC Felli, JD Forman-Kay, RW Kriwacki, R Pierattelli, J Sussman, DI Svergun, VN Uversky, M Vendruscolo, D Wishart, PE Wright, P Tompa
Nucleic Acids Res
(2013)
42
(doi: 10.1093/nar/gkt960)
Highlights from the 48th EUCHEM conference on stereochemistry, Bürgenstock, Switzerland, May 2013.
GJL Bernardes
Chemical Communications
(2013)
49
(doi: 10.1039/c3cc90259e)
Site-specific chemical modification of antibody fragments using traceless cleavable linkers.
GJL Bernardes, M Steiner, I Hartmann, D Neri, G Casi
Nature protocols
(2013)
8
(doi: 10.1038/nprot.2013.121)
A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation
E De Genst, P-H Chan, E Pardon, S-TD Hsu, JR Kumita, J Christodoulou, L Menzer, DY Chirgadze, CV Robinson, S Muyldermans, A Matagne, L Wyns, CM Dobson, M Dumoulin
The journal of physical chemistry. B
(2013)
117
(doi: 10.1021/jp403425z)
Cucurbit[8]uril and blue-box: High-energy water release overwhelms electrostatic interactions
F Biedermann, M Vendruscolo, OA Scherman, A De Simone, WM Nau
Journal of the American Chemical Society
(2013)
135
(doi: 10.1021/ja407951x)
Subdomain architecture and stability of a giant repeat protein.
M Tsytlonok, P Sormanni, PJE Rowling, M Vendruscolo, LS Itzhaki
Journal of Physical Chemistry B
(2013)
117
(doi: 10.1021/jp402360x)
Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase.
A Pica, A Merlino, AK Buell, TPJ Knowles, E Pizzo, G D'Alessio, F Sica, L Mazzarella
Acta Crystallographica Section D, Structural Biology
(2013)
69
(doi: 10.1107/s0907444913020507)
Structures of the Excited States of Phospholamban and Shifts in Their Populations upon Phosphorylation
A De Simone, M Gustavsson, RW Montalvao, L Shi, G Veglia, M Vendruscolo
Biochemistry
(2013)
52
(doi: 10.1021/bi400517b)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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