Centre for Misfolding Diseases

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  • Currently displaying 1381 - 1400 of 2474 publications
Author(s)
Publication title
Journal Name
Publication year
Archaeal MBF1 binds to 30S and 70S ribosomes via its helix–turn–helix domain
F Blombach, H Launay, APL Snijders, V Zorraquino, H Wu, B de Koning, SJJ Brouns, TJG Ettema, C Camilloni, A Cavalli, M Vendruscolo, MJ Dickman, LD Cabrita, A La Teana, D Benelli, P Londei, J Christodoulou, J van der Oost
Biochem J
(2014)
462
(doi: 10.1042/BJ20131474)
Carbon-Monoxide-Releasing Molecules for the Delivery of Therapeutic CO In Vivo
S García-Gallego, GJL Bernardes
Angewandte Chemie International Edition
(2014)
53
(doi: 10.1002/anie.201311225)
Easyworm: an open-source software tool to determine the mechanical properties of worm-like chains.
G Lamour, JB Kirkegaard, H Li, TP Knowles, J Gsponer
Source Code for Biology and Medicine
(2014)
9
(doi: 10.1186/1751-0473-9-16)
Amyloid Beta Peptide Aβ40 and Aβ42 Form Separate Fibrils in Binary Mixtures
X Yang, R Cukalevski, G Meisl, B Frohm, T Knowles, S Linse
PROTEIN SCIENCE
(2014)
23
Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism.
C Camilloni, AB Sahakyan, MJ Holliday, NG Isern, F Zhang, EZ Eisenmesser, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1404220111)
Statistical mechanics of the denatured state of a protein using replica-averaged metadynamics.
C Camilloni, M Vendruscolo
J Am Chem Soc
(2014)
136
(doi: 10.1021/ja5027584)
Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides
G Meisl, X Yang, E Hellstrand, B Frohm, JB Kirkegaard, SIA Cohen, CM Dobson, S Linse, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1401564111)
A tensor-free method for the structural and dynamical refinement of proteins using residual dipolar couplings.
C Camilloni, M Vendruscolo
The Journal of Physical Chemistry B
(2014)
119
(doi: 10.1021/jp5021824)
Self‐Assembly of Amyloid Fibrils That Display Active Enzymes
X Zhou, A Entwistle, H Zhang, AP Jackson, TO Mason, U Shimanovich, TPJ Knowles, AT Smith, EB Sawyer, S Perrett
Chemcatchem
(2014)
6
(doi: 10.1002/cctc.201402125)
Role of filament annealing in the kinetics and thermodynamics of nucleated polymerization.
TCT Michaels, TPJ Knowles
The Journal of Chemical Physics
(2014)
140
(doi: 10.1063/1.4880121)
ALMOST: An all atom molecular simulation toolkit for protein structure determination
B Fu, AB Sahakyan, C Camilloni, GG Tartaglia, E Paci, A Caflisch, M Vendruscolo, A Cavalli
Journal of Computational Chemistry
(2014)
35
(doi: 10.1002/jcc.23588)
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour
G Fusco, A De Simone, T Gopinath, V Vostrikov, M Vendruscolo, CM Dobson, G Veglia
Nat Commun
(2014)
5
(doi: 10.1038/ncomms4827)
The amyloid state and its association with protein misfolding diseases.
TPJ Knowles, M Vendruscolo, CM Dobson
Nat Rev Mol Cell Biol
(2014)
15
(doi: 10.1038/nrm3810)
Direct observations of amyloid β Self-assembly in live cells provide insights into differences in the kinetics of Aβ(1-40) and Aβ(1-42) aggregation
EK Esbjörner, F Chan, E Rees, M Erdelyi, LM Luheshi, CW Bertoncini, CF Kaminski, CM Dobson, GS Kaminski Schierle
Chemistry & biology
(2014)
21
(doi: 10.1016/j.chembiol.2014.03.014)
Asymptotic solutions of the Oosawa model for the length distribution of biofilaments.
TCT Michaels, GA Garcia, TPJ Knowles
The Journal of chemical physics
(2014)
140
(doi: 10.1063/1.4875897)
Iterative derivation of effective potentials to sample the conformational space of proteins at atomistic scale.
R Capelli, C Paissoni, P Sormanni, G Tiana
The Journal of Chemical Physics
(2014)
140
(doi: 10.1063/1.4876219)
Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation
AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, S Linse, CM Dobson
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1315346111)
Hypochlorite-induced structural modifications enhance the chaperone activity of human α2-macroglobulin.
AR Wyatt, JR Kumita, RW Mifsud, CA Gooden, MR Wilson, CM Dobson
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1403379111)
Mean-field master equation formalism for biofilament growth
TCT Michaels, TPJ Knowles
American Journal of Physics
(2014)
82
(doi: 10.1119/1.4870004)
Understanding the influence of codon translation rates on cotranslational protein folding.
EP O'Brien, P Ciryam, M Vendruscolo, CM Dobson
Accounts of Chemical Research
(2014)
47
(doi: 10.1021/ar5000117)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
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