Centre for Misfolding Diseases

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  • Currently displaying 1361 - 1380 of 2508 publications
Author(s)
Publication title
Journal Name
Publication year
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.
SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, EJ De-Genst, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1421204112)
Investigating the mechanisms of amylolysis of starch granules by solution-state NMR
AJ Baldwin, DL Egan, FJ Warren, PD Barker, CM Dobson, PJ Butterworth, PR Ellis
Biomacromolecules
(2015)
16
(doi: 10.1021/acs.biomac.5b00190)
Folic acid-tagged protein nanoemulsions loaded with CORM-2 enhance the survival of mice bearing subcutaneous A20 lymphoma tumors.
A Loureiro, GJL Bernardes, U Shimanovich, MP Sárria, E Nogueira, A Preto, AC Gomes, A Cavaco-Paulo
Nanomedicine : nanotechnology, biology, and medicine
(2015)
11
(doi: 10.1016/j.nano.2015.02.022)
Structure and dynamics of the integrin LFA-1 I-domain in the inactive state underlie its inside-out/outside-in signaling and allosteric mechanisms
P Kukic, HT Alvin Leung, F Bemporad, FA Aprile, JR Kumita, A De Simone, C Camilloni, M Vendruscolo
Structure
(2015)
23
(doi: 10.1016/j.str.2014.12.020)
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
SIA Cohen, P Arosio, J Presto, FR Kurudenkandy, H Biverstål, L Dolfe, C Dunning, X Yang, B Frohm, M Vendruscolo, J Johansson, CM Dobson, A Fisahn, TPJ Knowles, S Linse
Nature structural & molecular biology
(2015)
22
(doi: 10.1038/nsmb.2971)
The physical basis of protein misfolding disorders
TPJ Knowles, M Vendruscolo, CM Dobson
Physics Today
(2015)
68
(doi: 10.1063/pt.3.2719)
The s2D method: Simultaneous sequence-based prediction of the statistical populations of ordered and disordered regions in proteins
P Sormanni, C Camilloni, P Fariselli, M Vendruscolo
Journal of Molecular Biology
(2015)
427
(doi: 10.1016/j.jmb.2014.12.007)
Chaperoned amyloid proteins for immune manipulation: α-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype.
A Labrador-Garrido, M Cejudo-Guillén, R Klippstein, EJ De Genst, L Tomas-Gallardo, MM Leal, J Villadiego, JJ Toledo-Aral, CM Dobson, D Pozo, C Roodveldt
Immun Inflamm Dis
(2015)
2
(doi: 10.1002/iid3.39)
Advances in chemical protein modification.
O Boutureira, GJL Bernardes
Chemical reviews
(2015)
115
(doi: 10.1021/cr500399p)
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation.
C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, TPJ Knowles, CM Dobson
Nature chemical biology
(2015)
11
(doi: 10.1038/NCHEMBIO.1750)
The CamSol method of rational design of protein mutants with enhanced solubility
P Sormanni, FA Aprile, M Vendruscolo
Journal of Molecular Biology
(2015)
427
(doi: 10.1016/j.jmb.2014.09.026)
The Computational Studies of Co-Translational Protein Folding
T Wlodarski, C Waudby, C Sammy, M Vendruscolo, J Christodoulou
Biophysical Journal
(2015)
108
(doi: 10.1016/j.bpj.2014.11.2823)
Protein microgels from amyloid fibril networks.
U Shimanovich, I Efimov, TO Mason, P Flagmeier, AK Buell, A Gedanken, S Linse, KS Åkerfeldt, CM Dobson, DA Weitz, TPJ Knowles
ACS nano
(2015)
9
(doi: 10.1021/nn504869d)
Structure of a low-population intermediate state in the release of an enzyme product.
A De Simone, FA Aprile, A Dhulesia, CM Dobson, M Vendruscolo
eLife
(2015)
2015
(doi: 10.7554/elife.02777)
Analysis of the hierarchical structure of the B. subtilis transcriptional regulatory network.
S Kumar, M Vendruscolo, A Singh, D Kumar, A Samal
Molecular Biosystems
(2015)
11
(doi: 10.1039/c4mb00298a)
Functionalized protein nanoemulsions by incorporation of chemically modified BSA
A Loureiro, AS Abreu, MP Sárria, MCO Figueiredo, LM Saraiva, GJL Bernardes, AC Gomes, A Cavaco-Paulo
Rsc Advances
(2015)
5
(doi: 10.1039/c4ra13802c)
An artificial CO-releasing metalloprotein built by histidine-selective metallation.
IS Albuquerque, HF Jeremias, M Chaves-Ferreira, D Matak-Vinkovic, O Boutureira, CC Romão, GJL Bernardes
Chem Commun (Camb)
(2015)
51
(doi: 10.1039/c4cc10204e)
MonteGrappa: An iterative Monte Carlo program to optimize biomolecular potentials in simplified models
G Tiana, F Villa, Y Zhan, R Capelli, C Paissoni, P Sormanni, E Heard, L Giorgetti, R Meloni
Computer Physics Communications
(2015)
186
(doi: 10.1016/j.cpc.2014.09.012)
Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates.
MA Wright, FA Aprile, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Chemical communications (Cambridge, England)
(2015)
51
(doi: 10.1039/c5cc03689e)
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, TPJ Knowles, CM Dobson
Nature Chemical Biology
(2015)
11
(doi: 10.1038/nchembio.1750)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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