Centre for Misfolding Diseases

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  • Currently displaying 1361 - 1380 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Probing the Interaction Between α-Synuclein and Lipid Membranes by NMR Spectroscopy
G Fusco, CM Dobson
BIOPHYSICAL JOURNAL
(2014)
106
Structural and Mechanistic Analyses of the Effects of Small Compounds on Amyloid Beta Self-Assembly
J Habchi, P Joshi, A Spilotros, D Svergun, M Vendruscolo
BIOPHYSICAL JOURNAL
(2014)
106
Insights into the Inhibition Mechanism of Biomolecular Self-Assembly from Chemical Kinetics
P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.3776)
Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation
FA Aprile, G Meisl, AK Buell, P Flagmeier, CM Dobson, M Vendruscolo, TPJ Knowles
BIOPHYSICAL JOURNAL
(2014)
106
Conformational Equilibrium between the Sub States of the Acidic Denatured State of ACBP Determined by NMR Chemical Shifts and Metadynamics
C Camilloni, M Vendruscolo
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.2605)
A Clear View of Polymorphism, Twist, and Chirality in Amyloid Fibril Formation
LR Volpatti, M Vendruscolo, CM Dobson, TPJ Knowles
ACS nano
(2013)
7
(doi: 10.1021/nn406121w)
Quantification of the concentration of Aβ42 propagons during the lag phase by an amyloid chain reaction assay
P Arosio, R Cukalevski, B Frohm, TPJ Knowles, S Linse
Journal of the American Chemical Society
(2013)
136
(doi: 10.1021/ja408765u)
Higher order amyloid fibril structure by MAS NMR and DNP spectroscopy
GT Debelouchina, MJ Bayro, AW Fitzpatrick, V Ladizhansky, MT Colvin, MA Caporini, CP Jaroniec, VS Bajaj, M Rosay, CE Macphee, M Vendruscolo, WE Maas, CM Dobson, RG Griffin
J Am Chem Soc
(2013)
135
(doi: 10.1021/ja409050a)
Protein micro- and nano-capsules for biomedical applications
U Shimanovich, GJL Bernardes, TPJ Knowles, A Cavaco-Paulo
Chem. Soc. Rev.
(2013)
43
(doi: 10.1039/c3cs60376h)
Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics via Two-Color Super-Resolution Microscopy
D Pinotsi, AK Buell, C Galvagnion, CM Dobson, GS Kaminski Schierle, CF Kaminski
Nano Lett
(2013)
14
(doi: 10.1021/nl4041093)
Polymer Physics Inspired Approaches for the Study of the Mechanical Properties of Amyloid Fibrils
LR Volpatti, TPJ Knowles
Journal of Polymer Science Part B: Polymer Physics
(2013)
52
(doi: 10.1002/polb.23428)
Replica-Averaged Metadynamics
C Camilloni, A Cavalli, M Vendruscolo
J Chem Theory Comput
(2013)
9
(doi: 10.1021/ct4006272)
Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation
C Roodveldt, A Labrador-Garrido, E Gonzalez-Rey, CC Lachaud, T Guilliams, R Fernandez-Montesinos, A Benitez-Rondan, G Robledo, A Hmadcha, M Delgado, CM Dobson, D Pozo
PLoS ONE
(2013)
8
(doi: 10.1371/journal.pone.0079160)
Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo
Cell Reports
(2013)
5
(doi: 10.1016/j.celrep.2013.09.043)
pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins
M Varadi, S Kosol, P Lebrun, E Valentini, M Blackledge, AK Dunker, IC Felli, JD Forman-Kay, RW Kriwacki, R Pierattelli, J Sussman, DI Svergun, VN Uversky, M Vendruscolo, D Wishart, PE Wright, P Tompa
Nucleic Acids Research
(2013)
42
(doi: 10.1093/nar/gkt960)
Highlights from the 48th EUCHEM conference on stereochemistry, Bürgenstock, Switzerland, May 2013
GJL Bernardes
Chem Commun (Camb)
(2013)
49
(doi: 10.1039/c3cc90259e)
Site-specific chemical modification of antibody fragments using traceless cleavable linkers.
GJL Bernardes, M Steiner, I Hartmann, D Neri, G Casi
Nature Protocols
(2013)
8
(doi: 10.1038/nprot.2013.121)
A Nanobody Binding to Non-Amyloidogenic Regions of the Protein Human Lysozyme Enhances Partial Unfolding but Inhibits Amyloid Fibril Formation
E De Genst, P-H Chan, E Pardon, S-TD Hsu, JR Kumita, J Christodoulou, L Menzer, DY Chirgadze, CV Robinson, S Muyldermans, A Matagne, L Wyns, CM Dobson, M Dumoulin
J Phys Chem B
(2013)
117
(doi: 10.1021/jp403425z)
Cucurbit[8]uril and Blue-Box: High-Energy Water Release Overwhelms Electrostatic Interactions
F Biedermann, M Vendruscolo, OA Scherman, A De Simone, WM Nau
J Am Chem Soc
(2013)
135
(doi: 10.1021/ja407951x)
Subdomain architecture and stability of a giant repeat protein.
M Tsytlonok, P Sormanni, PJE Rowling, M Vendruscolo, LS Itzhaki
The Journal of Physical Chemistry B
(2013)
117
(doi: 10.1021/jp402360x)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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