Centre for Misfolding Diseases

Publications

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  • Currently displaying 1361 - 1380 of 2403 publications
Author(s)
Publication title
Journal Name
Publication year
Nanoscale spatially resolved infrared spectra from single microdroplets.
T Müller, FS Ruggeri, AJ Kulik, U Shimanovich, TO Mason, TPJ Knowles, G Dietler
Lab on a chip
(2014)
14
(doi: 10.1039/c3lc51219c)
Chemical kinetics for drug discovery to combat protein aggregation diseases
P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Trends in Pharmacological Sciences
(2014)
35
Elucidating the Structural Basis of α-Synuclein Fibrillation using Small Camelid Nanobodies
FE Turk, G Tomba, E De Genst, T Guillams, P Kukic, M Vendruscolo, C Dobson
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.1512)
Amyloid Beta Peptide Aβ40 and Aβ42 Form Separate Fibrils in Binary Mixtures
X Yang, R Cukalevski, G Meisl, B Frohm, T Knowles, S Linse
PROTEIN SCIENCE
(2014)
23
Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation
FA Aprile, G Meisl, AK Buell, P Flagmeier, CM Dobson, M Vendruscolo, TPJ Knowles
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.1570)
MD Simulations of Intrinsically Disordered Proteins with Replica-Averaged Chemical Shift Restraints
B Fu, P Kukic, C Camilloni, M Vendruscolo
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.2714)
Single-Molecule Characterisation of Alpha-Synuclein Oligomers
MH Horrocks, SF Lee, S Gandhi, M Iljina, L Tosatto, CM Dobson, D Klenerman
BIOPHYSICAL JOURNAL
(2014)
106
Chapter 41 Structure of a Misfolded Intermediate of a PDZ Domain
A De Simone, S Gianni, M Vendruscolo
(2014)
(doi: 10.1016/b978-0-12-394431-3.00041-9)
Proteome Metastability in Health, Aging, and Disease
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, EP O'Brien, M Vendruscolo
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.405)
A clear view of polymorphism, twist, and chirality in amyloid fibril formation
LR Volpatti, M Vendruscolo, CM Dobson, TPJ Knowles
ACS Nano
(2013)
7
(doi: 10.1021/nn406121w)
Quantification of the Concentration of Aβ42 Propagons during the Lag Phase by an Amyloid Chain Reaction Assay
P Arosio, R Cukalevski, B Frohm, TPJ Knowles, S Linse
Journal of the American Chemical Society
(2013)
136
(doi: 10.1021/ja408765u)
Higher order amyloid fibril structure by MAS NMR and DNP spectroscopy
GT Debelouchina, MJ Bayro, AW Fitzpatrick, V Ladizhansky, MT Colvin, MA Caporini, CP Jaroniec, VS Bajaj, M Rosay, CE Macphee, M Vendruscolo, WE Maas, CM Dobson, RG Griffin
J Am Chem Soc
(2013)
135
(doi: 10.1021/ja409050a)
Protein micro- and nano-capsules for biomedical applications.
U Shimanovich, GJL Bernardes, TPJ Knowles, A Cavaco-Paulo
Chem. Soc. Rev.
(2013)
43
(doi: 10.1039/c3cs60376h)
Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy.
D Pinotsi, AK Buell, C Galvagnion, CM Dobson, GS Kaminski Schierle, CF Kaminski
Nano Letters
(2013)
14
(doi: 10.1021/nl4041093)
Polymer physics inspired approaches for the study of the mechanical properties of amyloid fibrils
LR Volpatti, TPJ Knowles
Journal of Polymer Science Part B Polymer Physics
(2013)
52
(doi: 10.1002/polb.23428)
Replica-averaged metadynamics
C Camilloni, A Cavalli, M Vendruscolo
J Chem Theory Comput
(2013)
9
(doi: 10.1021/ct4006272)
Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation
C Roodveldt, A Labrador-Garrido, E Gonzalez-Rey, CC Lachaud, T Guilliams, R Fernandez-Montesinos, A Benitez-Rondan, G Robledo, A Hmadcha, M Delgado, CM Dobson, D Pozo
PLoS ONE
(2013)
8
(doi: 10.1371/journal.pone.0079160)
Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins.
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo
Cell reports
(2013)
5
(doi: 10.1016/j.celrep.2013.09.043)
pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins.
M Varadi, S Kosol, P Lebrun, E Valentini, M Blackledge, AK Dunker, IC Felli, JD Forman-Kay, RW Kriwacki, R Pierattelli, J Sussman, DI Svergun, VN Uversky, M Vendruscolo, D Wishart, PE Wright, P Tompa
Nucleic Acids Res
(2013)
42
(doi: 10.1093/nar/gkt960)
Highlights from the 48th EUCHEM conference on stereochemistry, Burgenstock, Switzerland, May 2013
GJL Bernardes
Chem Commun (Camb)
(2013)
49
(doi: 10.1039/c3cc90259e)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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