Centre for Misfolding Diseases

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  • Currently displaying 1321 - 1340 of 2484 publications
Author(s)
Publication title
Journal Name
Publication year
Rapid sizing of proteins in complex solutions
P Arosio, T Muller, L Rajah, EV Yates, FA Aprile, SIA Cohen, DA White, TW Herling, E de Genst, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies
AR Wyatt, JR Kumita, NE Farrawell, CM Dobson, MR Wilson
PLoS One
(2015)
10
(doi: 10.1371/journal.pone.0130036)
89 Constructing free energy landscapes of RNAs at atomic resolution and characterisation of their excited states
AN Borkar, P Vallurupalli, C Camilloni, LE Kay, M Vendruscolo
J Biomol Struct Dyn
(2015)
33 Suppl 1
(doi: 10.1080/07391102.2015.1032706)
Constructing free energy landscapes of RNAs at atomic resolution and characterisation of their excited states
PNA Okai, E Agustin, MR Miller, J Sheng, M Royzen
Journal of Biomolecular Structure and Dynamics
(2015)
33
(doi: 10.1080/07391102.2015.1032703)
Structure of a single-chain Fv bound to the 17 N-terminal residues of huntingtin provides insights into pathogenic amyloid formation and suppression
E De Genst, DY Chirgadze, FAC Klein, DC Butler, D Matak-Vinković, Y Trottier, JS Huston, A Messer, CM Dobson
Journal of Molecular Biology
(2015)
427
(doi: 10.1016/j.jmb.2015.03.021)
Reply to "comment on A Tensor-Free Method for the Structural and Dynamic Refinement of Proteins using Residual Dipolar Couplings"
C Camilloni, M Vendruscolo
Journal of Physical Chemistry B
(2015)
119
(doi: 10.1021/acs.jpcb.5b04166)
Enzymatically Active Microgels from Self-Assembling Protein Nanofibrils for Microflow Chemistry.
X-M Zhou, U Shimanovich, TW Herling, S Wu, CM Dobson, TPJ Knowles, S Perrett
ACS nano
(2015)
9
(doi: 10.1021/acsnano.5b00061)
Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity.
J Dworzak, B Renvoisé, J Habchi, EV Yates, C Combadière, TP Knowles, CM Dobson, C Blackstone, O Paulsen, PM Murphy
PloS one
(2015)
10
(doi: 10.1371/journal.pone.0127730)
Synthesis of fluorosugar reagents for the construction of well-defined fluoroglycoproteins.
M Salvadó, B Amgarten, S Castillón, GJL Bernardes, O Boutureira
Org Lett
(2015)
17
(doi: 10.1021/acs.orglett.5b01259)
Analysis of the performance of the CHESHIRE and YAPP methods at CASD-NMR round 3.
A Cavalli, M Vendruscolo
Journal of biomolecular NMR
(2015)
62
(doi: 10.1007/s10858-015-9940-9)
Aggregation-Prone Amyloid-CuII Species Formed on the Millisecond Timescale under Mildly Acidic Conditions
JT Pedersen, CB Borg, TCT Michaels, TPJ Knowles, P Faller, K Teilum, L Hemmingsen
Chembiochem
(2015)
16
(doi: 10.1002/cbic.201500080)
Structure and dynamics of GeoCyp: A thermophilic cyclophilin with a novel substrate binding mechanism that functions efficiently at low temperatures
MJ Holliday, C Camilloni, GS Armstrong, NG Isern, F Zhang, M Vendruscolo, EZ Eisenmesser
Biochemistry
(2015)
54
(doi: 10.1021/acs.biochem.5b00263)
The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation.
R Cukalevski, X Yang, G Meisl, U Weininger, K Bernfur, B Frohm, TPJ Knowles, S Linse
Chemical Science
(2015)
6
(doi: 10.1039/c4sc02517b)
Widespread proteome remodeling and aggregation in aging C. elegans
DM Walther, P Kasturi, M Zheng, S Pinkert, G Vecchi, P Ciryam, RI Morimoto, CM Dobson, M Vendruscolo, M Mann, FU Hartl
Cell
(2015)
161
(doi: 10.1016/j.cell.2015.03.032)
Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation
E Lira-Navarrete, M de Las Rivas, I Compañón, MC Pallarés, Y Kong, J Iglesias-Fernández, GJL Bernardes, JM Peregrina, C Rovira, P Bernadó, P Bruscolini, H Clausen, A Lostao, F Corzana, R Hurtado-Guerrero
Nat Commun
(2015)
6
(doi: 10.1038/ncomms7937)
A mechanistic model of tau amyloid aggregation based on direct observation of oligomers.
SL Shammas, GA Garcia, S Kumar, M Kjaergaard, MH Horrocks, N Shivji, E Mandelkow, TPJ Knowles, E Mandelkow, D Klenerman
Nat Commun
(2015)
6
(doi: 10.1038/ncomms8025)
The influence of novel gemini surfactants containing cycloalkyl side-chains on the structural phases of DNA in solution.
Z Pietralik, JR Kumita, CM Dobson, M Kozak
Colloids and Surfaces B Biointerfaces
(2015)
131
(doi: 10.1016/j.colsurfb.2015.04.042)
Preventing peptide and protein misbehavior.
P Arosio, G Meisl, M Andreasen, TPJ Knowles
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1505170112)
Investigating the Mechanisms of Amylolysis of Starch Granules by Solution-State NMR
AJ Baldwin, DL Egan, FJ Warren, PD Barker, CM Dobson, PJ Butterworth, PR Ellis
Biomacromolecules
(2015)
16
(doi: 10.1021/acs.biomac.5b00190)
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation
SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, EJ De-Genst, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proc Natl Acad Sci U S A
(2015)
112
(doi: 10.1073/pnas.1421204112)
Yusuf Hamied Department of Chemistry
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