Centre for Misfolding Diseases

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  • Currently displaying 1321 - 1340 of 2338 publications
Author(s)
Publication title
Journal Name
Publication year
Using single molecule techniques to find out how the major protein associated with Parkinson's disease
MH Horrocks, L Tosatto, N Cremades, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2013)
42
MD simulations of intrinsically disordered proteins with replica-averaged chemical shift restraints
B Fu, C Camilloni, A Cavalli, M Vendruscolo
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2013)
42
Structure of a Misfolded Intermediate of a PDZ Domain
A De Simone, S Gianni, M Vendruscolo
Bio-nanoimaging: Protein Misfolding and Aggregation
(2013)
(doi: 10.1016/B978-0-12-394431-3.00041-9)
New approaches to understanding and preventing neurodegenerative diseases
CM Dobson
PRION
(2013)
7
Thermodynamics of an Intrinsically Disordered Protein by Atomistic Simulations
D Granata, FB Baghal, C Camilloni, M Vendruscolo, A Laio
Biophysical Journal
(2013)
104
(doi: 10.1016/j.bpj.2012.11.344)
Chemoselective transformations for bioimaging and targeted therapeutics
GJL Bernardes
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2013)
42
Characterization of Free Energy Landscapes of Proteins using NMR Spectroscopy
M Vendruscolo
Biophysical Journal
(2013)
104
(doi: 10.1016/j.bpj.2012.11.287)
Spacer length shapes drug release and therapeutic efficacy of traceless disulfide-linked ADCs targeting the tumor neovasculature
M Steiner, I Hartmann, E Perrino, G Casi, S Brighton, I Jelesarov, GJL Bernardes, D Neri
Chem. Sci.
(2013)
4
(doi: 10.1039/c2sc21107f)
In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome.
P Ciryam, RI Morimoto, M Vendruscolo, CM Dobson, EP O'Brien
Proc Natl Acad Sci U S A
(2012)
110
(doi: 10.1073/pnas.1213624110)
Analysis of the native structure, stability and aggregation of biotinylated human lysozyme.
M Ahn, E De Genst, GS Kaminski Schierle, M Erdelyi, CF Kaminski, CM Dobson, JR Kumita
Plos One
(2012)
7
(doi: 10.1371/journal.pone.0050192)
Amyloid‑β Oligomers are Sequestered by both Intracellular and Extracellular Chaperones
P Narayan, S Meehan, JA Carver, MR Wilson, CM Dobson, D Klenerman
Biochemistry
(2012)
51
(doi: 10.1021/bi301277k)
A Rationally Designed Six-Residue Swap Generates Comparability in the Aggregation Behavior of α-Synuclein and β-Synuclein
C Roodveldt, A Andersson, EJ De Genst, A Labrador-Garrido, AK Buell, CM Dobson, GG Tartaglia, M Vendruscolo
Biochemistry
(2012)
51
(doi: 10.1021/bi300558q)
Connecting macroscopic observables and microscopic assembly events in amyloid formation using coarse grained simulations.
NS Bieler, TPJ Knowles, D Frenkel, R Vácha
PLoS Comput Biol
(2012)
8
(doi: 10.1371/journal.pcbi.1002692)
Twisting transition between crystalline and fibrillar phases of aggregated peptides.
TPJ Knowles, A De Simone, AW Fitzpatrick, A Baldwin, S Meehan, L Rajah, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev
Phys Rev Lett
(2012)
109
(doi: 10.1103/physrevlett.109.158101)
Highly non-linear microfluidic resistor elements for flow rate-dependent addressing of microchannels
L Rajah, DA White, TPJ Knowles
International Journal of Nonlinear Sciences and Numerical Simulation
(2012)
13
(doi: 10.1515/ijnsns-2012-0401)
In support of the BMRB
JL Markley, H Akutsu, T Asakura, M Baldus, R Boelens, A Bonvin, R Kaptein, A Bax, I Bezsonova, MR Gryk, JC Hoch, DM Korzhnev, MW Maciejewski, D Case, WJ Chazin, TA Cross, S Dames, H Kessler, O Lange, T Madl, B Reif, M Sattler, D Eliezer, A Fersht, J Forman-Kay, LE Kay, J Fraser, J Gross, T Kortemme, A Sali, T Fujiwara, K Gardner, X Luo, J Rizo-Rey, M Rosen, RR Gil, C Ho, G Rule, AM Gronenborn, R Ishima, J Klein-Seetharaman, P Tang, P van der Wel, Y Xu, S Grzesiek, S Hiller, J Seelig, ED Laue, H Mott, D Nietlispach, I Barsukov, L-Y Lian, D Middleton, T Blumenschein, G Moore, I Campbell, J Schnell, IJ Vakonakis, A Watts, MR Conte, J Mason, M Pfuhl, MR Sanderson, J Craven, M Williamson, C Dominguez, G Roberts, U Günther, M Overduin, J Werner, P Williamson, C Blindauer, M Crump, P Driscoll, T Frenkiel, A Golovanov, S Matthews, J Parkinson, D Uhrin, M Williams, D Neuhaus, H Oschkinat, A Ramos, DE Shaw, C Steinbeck, M Vendruscolo, GW Vuister, KJ Walters, H Weinstein, K Wüthrich, S Yokoyama
Nature structural & molecular biology
(2012)
19
(doi: 10.1038/nsmb.2371)
Sequence-based prediction of protein solubility
F Agostini, M Vendruscolo, GG Tartaglia
Journal of Molecular Biology
(2012)
421
(doi: 10.1016/j.jmb.2011.12.005)
From macroscopic measurements to microscopic mechanisms of protein aggregation
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
Journal of Molecular Biology
(2012)
421
(doi: 10.1016/j.jmb.2012.02.031)
ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load.
JE Chambers, K Petrova, G Tomba, M Vendruscolo, D Ron
Journal of Cell Biology
(2012)
198
(doi: 10.1083/jcb.201202005)
Determination of structural fluctuations of proteins from structure-based calculations of residual dipolar couplings
RW Montalvao, A De Simone, M Vendruscolo
Journal of Biomolecular NMR
(2012)
53
(doi: 10.1007/s10858-012-9644-3)
Yusuf Hamied Department of Chemistry
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