Centre for Misfolding Diseases

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  • Currently displaying 1321 - 1340 of 2455 publications
Author(s)
Publication title
Journal Name
Publication year
Self‐Assembly of Amyloid Fibrils That Display Active Enzymes
X Zhou, A Entwistle, H Zhang, AP Jackson, TO Mason, U Shimanovich, TPJ Knowles, AT Smith, EB Sawyer, S Perrett
ChemCatChem
(2014)
6
(doi: 10.1002/cctc.201402125)
Role of filament annealing in the kinetics and thermodynamics of nucleated polymerization
TCT Michaels, TPJ Knowles
Journal of Chemical Physics
(2014)
140
(doi: 10.1063/1.4880121)
ALMOST: An all atom molecular simulation toolkit for protein structure determination
B Fu, AB Sahakyan, C Camilloni, GG Tartaglia, E Paci, A Caflisch, M Vendruscolo, A Cavalli
Journal of Computational Chemistry
(2014)
35
(doi: 10.1002/jcc.23588)
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour
G Fusco, A De Simone, T Gopinath, V Vostrikov, M Vendruscolo, CM Dobson, G Veglia
Nature communications
(2014)
5
(doi: 10.1038/ncomms4827)
The amyloid state and its association with protein misfolding diseases
TPJ Knowles, M Vendruscolo, CM Dobson
Nature reviews. Molecular cell biology
(2014)
15
(doi: 10.1038/nrm3810)
Direct Observations of Amyloid β Self-Assembly in Live Cells Provide Insights into Differences in the Kinetics of Aβ(1-40) and Aβ(1-42) Aggregation
EK Esbjörner, F Chan, E Rees, M Erdelyi, LM Luheshi, CW Bertoncini, CF Kaminski, CM Dobson, GS Kaminski Schierle
Chemistry & Biology
(2014)
21
(doi: 10.1016/j.chembiol.2014.03.014)
Asymptotic solutions of the Oosawa model for the length distribution of biofilaments
TCT Michaels, GA Garcia, TPJ Knowles
Journal of Chemical Physics
(2014)
140
(doi: 10.1063/1.4875897)
Iterative derivation of effective potentials to sample the conformational space of proteins at atomistic scale
R Capelli, C Paissoni, P Sormanni, G Tiana
Journal of Chemical Physics
(2014)
140
(doi: 10.1063/1.4876219)
Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation
AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, S Linse, CM Dobson
Proceedings of the National Academy of Sciences
(2014)
111
(doi: 10.1073/pnas.1315346111)
Hypochlorite-induced structural modifications enhance the chaperone activity of human α2-macroglobulin.
AR Wyatt, JR Kumita, RW Mifsud, CA Gooden, MR Wilson, CM Dobson
Proc Natl Acad Sci U S A
(2014)
111
(doi: 10.1073/pnas.1403379111)
Mean-field master equation formalism for biofilament growth
TCT Michaels, TPJ Knowles
American Journal of Physics
(2014)
82
(doi: 10.1119/1.4870004)
Understanding the Influence of Codon Translation Rates on Cotranslational Protein Folding
EP O'Brien, P Ciryam, M Vendruscolo, CM Dobson
Accounts of Chemical Research
(2014)
47
(doi: 10.1021/ar5000117)
Curative properties of noninternalizing antibody-drug conjugates based on maytansinoids
E Perrino, M Steiner, N Krall, GJL Bernardes, F Pretto, G Casi, D Neri
Cancer Res
(2014)
74
(doi: 10.1158/0008-5472.can-13-2990)
ChemInform Abstract: Protein Micro‐ and Nano‐Capsules for Biomedical Applications
U Shimanovich, GJL Bernardes, TPJ Knowles, A Cavaco‐Paulo
ChemInform
(2014)
45
(doi: 10.1002/chin.201418286)
Determination of the individual roles of the linker residues in the interdomain motions of calmodulin using NMR chemical shifts
P Kukic, C Camilloni, A Cavalli, M Vendruscolo
Journal of Molecular Biology
(2014)
106
(doi: 10.1016/j.jmb.2014.02.002)
Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies
J Wacker, R Rönicke, M Westermann, M Wulff, KG Reymann, CM Dobson, U Horn, DC Crowther, LM Luheshi, M Fändrich
Acta Neuropathologica Communications
(2014)
2
(doi: 10.1186/2051-5960-2-43)
Rare Individual Amyloid‑β Oligomers Act on Astrocytes to Initiate Neuronal Damage
P Narayan, KM Holmström, D-H Kim, DJ Whitcomb, MR Wilson, P St George-Hyslop, NW Wood, CM Dobson, K Cho, AY Abramov, D Klenerman
Biochemistry
(2014)
53
(doi: 10.1021/bi401606f)
Density-Gradient-Free Microfluidic Centrifugation for Analytical and Preparative Separation of Nanoparticles
P Arosio, T Müller, L Mahadevan, TPJ Knowles
Nano letters
(2014)
14
(doi: 10.1021/nl404771g)
New opportunities for tensor-free calculations of residual dipolar couplings for the study of protein dynamics
R Montalvao, C Camilloni, A De Simone, M Vendruscolo
Journal of Biomolecular NMR
(2014)
58
(doi: 10.1007/s10858-013-9801-3)
ALMOST: an all atom molecular simulation toolkit for protein structure determination.
B Fu, AB Sahakyan, C Camilloni, GG Tartaglia, E Paci, A Caflisch, M Vendruscolo, A Cavalli
Journal of Computational Chemistry
(2014)
35
(doi: 10.1002/jcc.23588)
Yusuf Hamied Department of Chemistry
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