Publications

Tips on using this search form

All search terms are case-insensitive
If you specify more than one search option (e.g. you search for both "Authors" and "Paper title") then the publications returned will be those that match all of your search terms
To reset the search form, click here

Currently displaying 1321 - 1340 of 2508 publications

Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies

M Pickhardt, EM Mandelkow, E Mandelkow

Current medicinal chemistry

(2015)

814

(doi: 10.2174/156720501209151019104951)

An N-Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species.

JD Seixas, M Chaves-Ferreira, D Montes-Grajales, AM Gonçalves, AR Marques, LM Saraiva, J Olivero-Verbel, CC Romão, GJL Bernardes

Chemistry

(2015)

14708

(doi: 10.1002/chem.201502474)

Chromatin Unfolding by Epigenetic Modifications Explained by Dramatic Impairment of Internucleosome Interactions: A Multiscale Computational Study

R Collepardo-Guevara, G Portella, M Vendruscolo, D Frenkel, T Schlick, M Orozco

Journal of the American Chemical Society

(2015)

137

10205

(doi: 10.1021/jacs.5b04086)

Alzheimer's disease: addressing a twenty-first century plague

CM Dobson

Rendiconti Lincei. Scienze Fisiche e Naturali

(2015)

251

(doi: 10.1007/s12210-015-0453-y)

Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α‑Synuclein Oligomers

MH Horrocks, L Tosatto, AJ Dear, GA Garcia, M Iljina, N Cremades, M Dalla Serra, TPJ Knowles, CM Dobson, D Klenerman

Analytical chemistry

(2015)

8818

(doi: 10.1021/acs.analchem.5b01811)

Peptide Anchor for Folate-Targeted Liposomal Delivery.

E Nogueira, IC Mangialavori, A Loureiro, NG Azoia, MP Sárria, P Nogueira, J Freitas, J Härmark, U Shimanovich, A Rollett, G Lacroix, GJL Bernardes, G Guebitz, H Hebert, A Moreira, AM Carmo, JPFC Rossi, AC Gomes, A Preto, A Cavaco-Paulo

Biomacromolecules

(2015)

2904

(doi: 10.1021/acs.biomac.5b00823)

A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate

FA Aprile, P Sormanni, M Vendruscolo

Biochemistry

(2015)

5103

(doi: 10.1021/acs.biochem.5b00459)

Dynamics of protein aggregation and oligomer formation governed by secondary nucleation.

TCT Michaels, HW Lazell, P Arosio, TPJ Knowles

Journal of Chemical Physics

(2015)

143

054901

(doi: 10.1063/1.4927655)

Force generation by the growth of amyloid aggregates.

TW Herling, GA Garcia, TCT Michaels, W Grentz, J Dean, U Shimanovich, H Gang, T Müller, B Kav, EM Terentjev, CM Dobson, TPJ Knowles

Proceedings of the National Academy of Sciences of the United States of America

(2015)

112

9524

(doi: 10.1073/pnas.1417326112)

Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody

N Martínez-Sáez, J Castro-Lõpez, J Valero-González, D Madariaga, I Compañõn, VJ Somovilla, M Salvadõ, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJL Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana

Angewandte Chemie International Edition

(2015)

9830

(doi: 10.1002/anie.201502813)

Molecular Rotors Provide Insights into Microscopic Structural Changes During Protein Aggregation.

AJ Thompson, TW Herling, M Kubánková, A Vyšniauskas, TPJ Knowles, MK Kuimova

Journal of Physical Chemistry B

(2015)

119

10170

(doi: 10.1021/acs.jpcb.5b05099)

Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins.

P Sormanni, FA Aprile, M Vendruscolo

Proceedings of the National Academy of Sciences of the United States of America

(2015)

112

9902

(doi: 10.1073/pnas.1422401112)

Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy

Y Pustovalova, P Kukic, M Vendruscolo, DM Korzhnev

Biochemistry

(2015)

4611

(doi: 10.1021/acs.biochem.5b00345)

Size controlled protein nanoemulsions for active targeting of folate receptor positive cells

A Loureiro, E Nogueira, NG Azoia, MP Sárria, AS Abreu, U Shimanovich, A Rollett, J Härmark, H Hebert, G Guebitz, GJL Bernardes, A Preto, AC Gomes, A Cavaco-Paulo

Colloids Surf B Biointerfaces

(2015)

135

(doi: 10.1016/j.colsurfb.2015.06.073)

Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution

KD Brewer, T Bacaj, A Cavalli, C Camilloni, JD Swarbrick, J Liu, A Zhou, P Zhou, N Barlow, J Xu, AB Seven, EA Prinslow, R Voleti, D Häussinger, AMJJ Bonvin, DR Tomchick, M Vendruscolo, B Graham, TC Südhof, J Rizo

Nature Structural and Molecular Biology

(2015)

555

(doi: 10.1038/nsmb.3035)

Rapid sizing of proteins in complex solutions

P Arosio, T Muller, L Rajah, EV Yates, FA Aprile, SIA Cohen, DA White, TW Herling, E de Genst, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles