Centre for Misfolding Diseases

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  • Currently displaying 1321 - 1340 of 2523 publications
Author(s)
Publication title
Journal Name
Publication year
ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, AR Costa, RB Dodd, FTS Chan, CH Michel, D Kronenberg-Versteeg, Y Li, S-P Yang, Y Wakutani, W Meadows, RR Ferry, L Dong, GG Tartaglia, G Favrin, W-L Lin, DW Dickson, M Zhen, D Ron, G Schmitt-Ulms, PE Fraser, NA Shneider, C Holt, M Vendruscolo, CF Kaminski, P St George-Hyslop
Neuron
(2015)
88
(doi: 10.1016/j.neuron.2015.10.030)
Mapping the Protein Fold Universe Using the CamTube Force Field in Molecular Dynamics Simulations.
P Kukic, A Kannan, MJJ Dijkstra, S Abeln, C Camilloni, M Vendruscolo
Plos Computational Biology
(2015)
11
(doi: 10.1371/journal.pcbi.1004435)
The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments
D Granata, F Baftizadeh, J Habchi, C Galvagnion, A De Simone, C Camilloni, A Laio, M Vendruscolo
Scientific reports
(2015)
5
(doi: 10.1038/srep15449)
ChemInform Abstract: Biophysical Approaches for the Study of Interactions Between Molecular Chaperones and Protein Aggregates
MA Wright, FA Aprile, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
ChemInform
(2015)
46
(doi: 10.1002/chin.201545294)
The length distribution of frangible biofilaments.
TCT Michaels, P Yde, JCW Willis, MH Jensen, D Otzen, CM Dobson, AK Buell, TPJ Knowles
The Journal of chemical physics
(2015)
143
(doi: 10.1063/1.4933230)
Sulfur‐Limonene Polysulfide: A Material Synthesized Entirely from Industrial By‐Products and Its Use in Removing Toxic Metals from Water and Soil
MP Crockett, AM Evans, MJH Worthington, IS Albuquerque, AD Slattery, CT Gibson, JA Campbell, DA Lewis, GJL Bernardes, JM Chalker
Angewandte Chemie - International Edition
(2015)
55
(doi: 10.1002/anie.201508708)
Targeting the N-myc oncoprotein using nanobody technology
L Kent, C Dobson, E de-Genst, H Laman
Molecular Cancer Research
(2015)
13
(doi: 10.1158/1557-3125.myc15-b35)
Particle-based simulations of steady-state mass transport at high Péclet numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
(2015)
Particle-based simulations of steady-state mass transport at high Péclet numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
(2015)
(doi: 10.48550/arxiv.1510.05126)
Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity
EV Yates, T Müller, L Rajah, EJ De Genst, P Arosio, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
Nature Chemistry
(2015)
7
(doi: 10.1038/nchem.2344)
Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the α-synuclein-elicited immune response
A Labrador-Garrido, M Cejudo-Guillén, S Daturpalli, MM Leal, R Klippstein, EJ De Genst, J Villadiego, JJ Toledo-Aral, CM Dobson, SE Jackson, D Pozo, C Roodveldt
FASEB Journal
(2015)
30
(doi: 10.1096/fj.15-275131)
Conformational effects of the A21G Flemish mutation on the aggregation of amyloid β peptide
M Yagi-Utsumi, CM Dobson
Biological & pharmaceutical bulletin
(2015)
38
(doi: 10.1248/bpb.b15-00466)
Sizing and interactions of proteins under native conditions from microfluidic diffusion measurements: application to molecular chaperones and single-step immunoassay
P Arosio, T Mueller, L Rajah, F Aprile, T Scheidt, J Carrozza, M Wright, M Vendruscolo, C Dobson, T Knowles
PROTEIN SCIENCE
(2015)
24
Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
PROTEIN SCIENCE
(2015)
24
Structure and Dynamics of Intrinsically Disordered Proteins
B Fu, M Vendruscolo
Adv Exp Med Biol
(2015)
870
(doi: 10.1007/978-3-319-20164-1_2)
Druggability of Intrinsically Disordered Proteins
P Joshi, M Vendruscolo
Adv Exp Med Biol
(2015)
870
(doi: 10.1007/978-3-319-20164-1_13)
Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies
M Pickhardt, EM Mandelkow, E Mandelkow
Current medicinal chemistry
(2015)
12
(doi: 10.2174/156720501209151019104951)
Targeting disordered proteins with small molecules using entropy
GT Heller, P Sormanni, M Vendruscolo
Trends in biochemical sciences
(2015)
40
(doi: 10.1016/j.tibs.2015.07.004)
An N‐Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species
JD Seixas, M Chaves-Ferreira, D Montes-Grajales, AM Gonçalves, AR Marques, LM Saraiva, J Olivero-Verbel, CC Romão, GJL Bernardes
Chemistry (Weinheim an der Bergstrasse, Germany)
(2015)
21
(doi: 10.1002/chem.201502474)
Chromatin unfolding by epigenetic modifications explained by dramatic impairment of internucleosome interactions: A multiscale computational study
R Collepardo-Guevara, G Portella, M Vendruscolo, D Frenkel, T Schlick, M Orozco
Journal of the American Chemical Society
(2015)
137
(doi: 10.1021/jacs.5b04086)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
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enquiries@ch.cam.ac.uk
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