Centre for Misfolding Diseases

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  • Currently displaying 1341 - 1360 of 2396 publications
Author(s)
Publication title
Journal Name
Publication year
Expanding the solvent chemical space for self-assembly of dipeptide nanostructures.
TO Mason, DY Chirgadze, A Levin, L Adler-Abramovich, E Gazit, TPJ Knowles, AK Buell
ACS Nano
(2014)
8
(doi: 10.1021/nn404237f)
A simple lattice model that captures protein folding, aggregation and amyloid formation.
S Abeln, M Vendruscolo, CM Dobson, D Frenkel
Plos One
(2014)
9
(doi: 10.1371/journal.pone.0085185)
Rationally designed short polyisoprenol-linked PglB substrates for engineered polypeptide and protein N-glycosylation
F Liu, B Vijayakrishnan, A Faridmoayer, TA Taylor, TB Parsons, GJL Bernardes, M Kowarik, BG Davis
Journal of the American Chemical Society
(2014)
136
(doi: 10.1021/ja409409h)
Kinetic modelling indicates that fast-translating codons can coordinate cotranslational protein folding by avoiding misfolded intermediates
EP O'Brien, M Vendruscolo, CM Dobson
Nature Communications
(2014)
5
(doi: 10.1038/ncomms3988)
Structural investigation of the folding of an immunoglobulin domain on the ribosome using NMR Spectroscopy
A Cassaignau, L Cabrita, C Waudby, X Wang, H Launay, C Camilloni, M-E Karyadi, S Chan, M Vendruscolo, C Dobson, J Christodoulou
FASEB JOURNAL
(2014)
28
Chapter 41 Structure of a Misfolded Intermediate of a PDZ Domain
A De Simone, S Gianni, M Vendruscolo
(2014)
(doi: 10.1016/b978-0-12-394431-3.00041-9)
Chemical kinetics for drug discovery to combat protein aggregation diseases
P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Trends in Pharmacological Sciences
(2014)
35
Conformational Equilibrium between the Sub States of the Acidic Denatured State of ACBP Determined by NMR Chemical Shifts and Metadynamics
C Camilloni, M Vendruscolo
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.2605)
Amyloid β-Protein: The Influence of Intrinsic and Extrinsic Factors on Fibril Formation
R Cukalevski, X Yang, S Cohen, B Boland, B Frohm, E Thulin, D Walsh, T Knowles, S Linse
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.3778)
Single-Molecule Characterisation of Alpha-Synuclein Oligomers
MH Horrocks, SF Lee, S Gandhi, M Iljina, L Tosatto, CM Dobson, D Klenerman
BIOPHYSICAL JOURNAL
(2014)
106
Structural and Mechanistic Analyses of the Effects of Small Compounds on Amyloid Beta Self-Assembly
J Habchi, P Joshi, A Spilotros, D Svergun, M Vendruscolo
BIOPHYSICAL JOURNAL
(2014)
106
Sonochemically-induced spectral shift as a probe of green fluorescent protein release from nano capsules
U Shimanovich, A Munder, NG Azoia, A Cavaco-Paulo, A Gruzman, TPJ Knowles, A Gedanken
RSC Advances
(2014)
4
(doi: 10.1039/c3ra47915c)
Elucidating the Structural Basis of α-Synuclein Fibrillation using Small Camelid Nanobodies
FE Turk, G Tomba, E De Genst, T Guillams, P Kukic, M Vendruscolo, C Dobson
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.1512)
Nanoscale spatially resolved infrared spectra from single microdroplets.
T Müller, FS Ruggeri, AJ Kulik, U Shimanovich, TO Mason, TPJ Knowles, G Dietler
Lab on a chip
(2014)
14
(doi: 10.1039/c3lc51219c)
MD Simulations of Intrinsically Disordered Proteins with Replica-Averaged Chemical Shift Restraints
B Fu, P Kukic, C Camilloni, M Vendruscolo
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.2714)
Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation
FA Aprile, G Meisl, AK Buell, P Flagmeier, CM Dobson, M Vendruscolo, TPJ Knowles
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.1570)
Amyloid Beta Peptide Aβ40 and Aβ42 Form Separate Fibrils in Binary Mixtures
X Yang, R Cukalevski, G Meisl, B Frohm, T Knowles, S Linse
PROTEIN SCIENCE
(2014)
23
Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation
FA Aprile, G Meisl, AK Buell, P Flagmeier, CM Dobson, M Vendruscolo, TPJ Knowles
BIOPHYSICAL JOURNAL
(2014)
106
Studying Distribution and Aggregation of TDP-43 in Mammalian Cells: A Comparison between Fluorescent Protein and Tetracysteine Labelling Strategies
JSW Ng, TP Barros, EK Esbjörner, LM Luheshi, JR Kumita, CM Dobson
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.2599)
Insights into the Inhibition Mechanism of Biomolecular Self-Assembly from Chemical Kinetics
P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.3776)
Yusuf Hamied Department of Chemistry
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