Centre for Misfolding Diseases

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  • Currently displaying 1341 - 1360 of 2453 publications
Author(s)
Publication title
Journal Name
Publication year
Ostwald’s rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers
A Levin, TO Mason, L Adler-Abramovich, AK Buell, G Meisl, C Galvagnion, Y Bram, SA Stratford, CM Dobson, TPJ Knowles, E Gazit
Nat Commun
(2014)
5
(doi: 10.1038/ncomms6219)
A Relationship between the Transient Structure in the Monomeric State and the Aggregation Propensities of α-Synuclein and β-Synuclein
JR Allison, RC Rivers, JC Christodoulou, M Vendruscolo, CM Dobson
Biochemistry
(2014)
53
(doi: 10.1021/bi5009326)
Single-MOLECULE IMAGING REVEALS THAT SMALL AMYLOID-β1-42 oligomers interact with the cellular prion protein (PrPC)
KA Ganzinger, P Narayan, SS Qamar, L Weimann, RT Ranasinghe, A Aguzzi, CM Dobson, J McColl, P St George-Hyslop, D Klenerman
Chembiochem
(2014)
15
(doi: 10.1002/cbic.201402377)
Cysteine-selective reactions for antibody conjugation
PMSD Cal, GJL Bernardes, PMP Gois
Angewandte Chemie International Edition
(2014)
53
(doi: 10.1002/anie.201405702)
Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein.
S Gianni, C Camilloni, R Giri, A Toto, D Bonetti, A Morrone, P Sormanni, M Brunori, M Vendruscolo
Proceedings of the National Academy of Sciences
(2014)
111
(doi: 10.1073/pnas.1405233111)
Identification and characterization of PKCγ, a kinase associated with SCA14, as an amyloidogenic protein
H Takahashi, N Adachi, T Shirafuji, S Danno, T Ueyama, M Vendruscolo, AN Shuvaev, T Sugimoto, T Seki, D Hamada, K Irie, H Hirai, N Sakai, N Saito
Hum Mol Genet
(2014)
24
(doi: 10.1093/hmg/ddu472)
Interaction of the Molecular Chaperone DNAJB6 with Growing Amyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation*
C Månsson, P Arosio, R Hussein, HH Kampinga, RM Hashem, WC Boelens, CM Dobson, TPJ Knowles, S Linse, C Emanuelsson
J Biol Chem
(2014)
289
(doi: 10.1074/jbc.M114.595124)
Equilibrium simulations of proteins using molecular fragment replacement and NMR chemical shifts
W Boomsma, P Tian, J Frellsen, J Ferkinghoff-Borg, T Hamelryck, K Lindorff-Larsen, M Vendruscolo
Proceedings of the National Academy of Sciences
(2014)
111
(doi: 10.1073/pnas.1404948111)
NMR characterization of the conformational fluctuations of the human lymphocyte function-associated antigen-1 I-domain.
HTA Leung, P Kukic, C Camilloni, F Bemporad, A De Simone, FA Aprile, JR Kumita, M Vendruscolo
Protein Science
(2014)
23
(doi: 10.1002/pro.2538)
Antibodies and protein misfolding: From structural research tools to therapeutic strategies.
E De Genst, A Messer, CM Dobson
Biochimica et biophysica acta
(2014)
1844
(doi: 10.1016/j.bbapap.2014.08.016)
The physical chemistry of the amyloid phenomenon: Thermodynamics and kinetics of fi lamentous protein aggregation
AK Buell, CM Dobson, TPJ Knowles
Essays Biochem
(2014)
56
(doi: 10.1042/BSE0560011)
Highlights from the 49th EUCHEM Conference on Stereochemistry, Burgenstock, Switzerland, May 2014
GJL Bernardes, AL Lawrence
Chem Commun (Camb)
(2014)
50
(doi: 10.1039/c4cc90250e)
Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity
B Mannini, E Mulvihill, C Sgromo, R Cascella, R Khodarahmi, M Ramazzotti, CM Dobson, C Cecchi, F Chiti
ACS Chem Biol
(2014)
9
(doi: 10.1021/cb500505m)
Archaeal MBF1 binds to 30S and 70S ribosomes via its helix–turn–helix domain
F Blombach, H Launay, APL Snijders, V Zorraquino, H Wu, B de Koning, SJJ Brouns, TJG Ettema, C Camilloni, A Cavalli, M Vendruscolo, MJ Dickman, LD Cabrita, A La Teana, D Benelli, P Londei, J Christodoulou, J van der Oost
Biochem J
(2014)
462
(doi: 10.1042/bj20131474)
Carbon‐Monoxide‐Releasing Molecules for the Delivery of Therapeutic CO In Vivo
S García-Gallego, GJL Bernardes
Angewandte Chemie (International ed. in English)
(2014)
53
(doi: 10.1002/anie.201311225)
Easyworm: an open-source software tool to determine the mechanical properties of worm-like chains.
G Lamour, JB Kirkegaard, H Li, TP Knowles, J Gsponer
Source code for biology and medicine
(2014)
9
(doi: 10.1186/1751-0473-9-16)
Cyclophilin a catalyzes proline isomerization by an electrostatic handle mechanism
C Camilloni, AB Sahakyan, MJ Holliday, NG Isern, F Zhang, EZ Eisenmesser, M Vendruscolo
Proc Natl Acad Sci U S A
(2014)
111
(doi: 10.1073/pnas.1404220111)
Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides.
G Meisl, X Yang, E Hellstrand, B Frohm, JB Kirkegaard, SIA Cohen, CM Dobson, S Linse, TPJ Knowles
Proc Natl Acad Sci U S A
(2014)
111
(doi: 10.1073/pnas.1401564111)
Statistical Mechanics of the Denatured State of a Protein Using Replica-Averaged Metadynamics
C Camilloni, M Vendruscolo
Journal of the American Chemical Society
(2014)
136
(doi: 10.1021/ja5027584)
The amyloid state and its association with protein misfolding diseases (vol 15, pg 384, 2014)
TPJ Knowles, M Vendruscolo, CM Dobson
Nature Reviews Molecular Cell Biology
(2014)
15
(doi: 10.1038/nrm3826)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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