Centre for Misfolding Diseases

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  • Currently displaying 1341 - 1360 of 2523 publications
Author(s)
Publication title
Journal Name
Publication year
Alzheimer’s disease: addressing a twenty-first century plague
CM Dobson
Rendiconti Lincei. Scienze Fisiche e Naturali
(2015)
26
(doi: 10.1007/s12210-015-0453-y)
Fast flow microfluidics and single-molecule fluorescence for the rapid characterization of α-synuclein oligomers.
MH Horrocks, L Tosatto, AJ Dear, GA Garcia, M Iljina, N Cremades, M Dalla Serra, TPJ Knowles, CM Dobson, D Klenerman
Anal Chem
(2015)
87
(doi: 10.1021/acs.analchem.5b01811)
A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate.
FA Aprile, P Sormanni, M Vendruscolo
Biochemistry
(2015)
54
(doi: 10.1021/acs.biochem.5b00459)
Dynamics of protein aggregation and oligomer formation governed by secondary nucleation.
TCT Michaels, HW Lazell, P Arosio, TPJ Knowles
J Chem Phys
(2015)
143
(doi: 10.1063/1.4927655)
Peptide Anchor for Folate-Targeted Liposomal Delivery
E Nogueira, IC Mangialavori, A Loureiro, NG Azoia, MP Sárria, P Nogueira, J Freitas, J Härmark, U Shimanovich, A Rollett, G Lacroix, GJL Bernardes, G Guebitz, H Hebert, A Moreira, AM Carmo, JPFC Rossi, AC Gomes, A Preto, A Cavaco-Paulo
Biomacromolecules
(2015)
16
(doi: 10.1021/acs.biomac.5b00823)
Force generation by the growth of amyloid aggregates
TW Herling, GA Garcia, TCT Michaels, W Grentz, J Dean, U Shimanovich, H Gang, T Müller, B Kav, EM Terentjev, CM Dobson, TPJ Knowles
Proc Natl Acad Sci U S A
(2015)
112
(doi: 10.1073/pnas.1417326112)
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody
N Martínez-Sáez, J Castro-Lõpez, J Valero-González, D Madariaga, I Compañõn, VJ Somovilla, M Salvadõ, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJL Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana
Angewandte Chemie International Edition
(2015)
54
(doi: 10.1002/anie.201502813)
Molecular Rotors Provide Insights into Microscopic Structural Changes During Protein Aggregation
AJ Thompson, TW Herling, M Kubánková, A Vyšniauskas, TPJ Knowles, MK Kuimova
J Phys Chem B
(2015)
119
(doi: 10.1021/acs.jpcb.5b05099)
Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins
P Sormanni, FA Aprile, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2015)
112
(doi: 10.1073/pnas.1422401112)
Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy.
Y Pustovalova, P Kukic, M Vendruscolo, DM Korzhnev
Biochemistry
(2015)
54
(doi: 10.1021/acs.biochem.5b00345)
Size controlled protein nanoemulsions for active targeting of folate receptor positive cells
A Loureiro, E Nogueira, NG Azoia, MP Sárria, AS Abreu, U Shimanovich, A Rollett, J Härmark, H Hebert, G Guebitz, GJL Bernardes, A Preto, AC Gomes, A Cavaco-Paulo
Colloids and surfaces. B, Biointerfaces
(2015)
135
(doi: 10.1016/j.colsurfb.2015.06.073)
Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution
KD Brewer, T Bacaj, A Cavalli, C Camilloni, JD Swarbrick, J Liu, A Zhou, P Zhou, N Barlow, J Xu, AB Seven, EA Prinslow, R Voleti, D Häussinger, AMJJ Bonvin, DR Tomchick, M Vendruscolo, B Graham, TC Südhof, J Rizo
Nature Structural and Molecular Biology
(2015)
22
(doi: 10.1038/nsmb.3035)
Crucial role of non-specific interactions in amyloid nucleation
A Saric, YC Chebaro, TPJ Knowles, D Frenkel
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
Rapid sizing of proteins in complex solutions
P Arosio, T Muller, L Rajah, EV Yates, FA Aprile, SIA Cohen, DA White, TW Herling, E de Genst, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
New insights into the mechanism of amyloid formation by alpha-synuclein
AK Buell, C Galvagnion, CM Dobson, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer's disease
R Cascella, E Evangelisti, M Becatti, CM Dobson, F Chiti, M Stefani, C Cecchi
FEBS JOURNAL
(2015)
282
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
C Galvagnion, AK Buell, G Meisl, TC Michaels, M Vendruscolo, TPJ Knowles, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
Kinetics of protein aggregation
TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
Thioflavin-T: application for α-synuclein aggregation kinetics
IM van der Wateren, AK Buell, C Galvagnion, EV Yates, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies
AR Wyatt, JR Kumita, NE Farrawell, CM Dobson, MR Wilson
PLoS One
(2015)
10
(doi: 10.1371/journal.pone.0130036)
Yusuf Hamied Department of Chemistry
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