Centre for Misfolding Diseases

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  • Currently displaying 1301 - 1320 of 2403 publications
Author(s)
Publication title
Journal Name
Publication year
Antibodies and protein misfolding: From structural research tools to therapeutic strategies.
E De Genst, A Messer, CM Dobson
Biochimica et biophysica acta
(2014)
1844
(doi: 10.1016/j.bbapap.2014.08.016)
The physical chemistry of the amyloid phenomenon: Thermodynamics and kinetics of fi lamentous protein aggregation
AK Buell, CM Dobson, TPJ Knowles
Essays in Biochemistry
(2014)
56
(doi: 10.1042/bse0560011)
Highlights from the 49th EUCHEM Conference on Stereochemistry, Bürgenstock, Switzerland, May 2014
GJL Bernardes, AL Lawrence
Chem Commun (Camb)
(2014)
50
(doi: 10.1039/c4cc90250e)
Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity
B Mannini, E Mulvihill, C Sgromo, R Cascella, R Khodarahmi, M Ramazzotti, CM Dobson, C Cecchi, F Chiti
ACS Chem Biol
(2014)
9
(doi: 10.1021/cb500505m)
Archaeal MBF1 binds to 30S and 70S ribosomes via its helix–turn–helix domain
F Blombach, H Launay, APL Snijders, V Zorraquino, H Wu, B de Koning, SJJ Brouns, TJG Ettema, C Camilloni, A Cavalli, M Vendruscolo, MJ Dickman, LD Cabrita, A La Teana, D Benelli, P Londei, J Christodoulou, J van der Oost
Biochem J
(2014)
462
(doi: 10.1042/BJ20131474)
Carbon‐Monoxide‐Releasing Molecules for the Delivery of Therapeutic CO In Vivo
S García-Gallego, GJL Bernardes
Angewandte Chemie International Edition
(2014)
53
(doi: 10.1002/anie.201311225)
Easyworm: an open-source software tool to determine the mechanical properties of worm-like chains.
G Lamour, JB Kirkegaard, H Li, TP Knowles, J Gsponer
Source Code for Biology and Medicine
(2014)
9
(doi: 10.1186/1751-0473-9-16)
Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism
C Camilloni, AB Sahakyan, MJ Holliday, NG Isern, F Zhang, EZ Eisenmesser, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1404220111)
Statistical Mechanics of the Denatured State of a Protein Using Replica-Averaged Metadynamics
C Camilloni, M Vendruscolo
J Am Chem Soc
(2014)
136
(doi: 10.1021/ja5027584)
Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides
G Meisl, X Yang, E Hellstrand, B Frohm, JB Kirkegaard, SIA Cohen, CM Dobson, S Linse, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1401564111)
The amyloid state and its association with protein misfolding diseases (vol 15, pg 384, 2014)
TPJ Knowles, M Vendruscolo, CM Dobson
Nature Reviews Molecular Cell Biology
(2014)
15
(doi: 10.1038/nrm3826)
Self-assembly of amyloid fibrils that display active enzymes
X Zhou, A Entwistle, H Zhang, AP Jackson, TO Mason, U Shimanovich, TPJ Knowles, AT Smith, EB Sawyer, S Perrett
ChemCatChem
(2014)
6
(doi: 10.1002/cctc.201402125)
A Tensor-Free Method for the Structural and Dynamical Refinement of Proteins using Residual Dipolar Couplings
C Camilloni, M Vendruscolo
The journal of physical chemistry. B
(2014)
119
(doi: 10.1021/jp5021824)
Role of filament annealing in the kinetics and thermodynamics of nucleated polymerization
TCT Michaels, TPJ Knowles
Journal of Chemical Physics
(2014)
140
(doi: 10.1063/1.4880121)
ALMOST: An all atom molecular simulation toolkit for protein structure determination
B Fu, AB Sahakyan, C Camilloni, GG Tartaglia, E Paci, A Caflisch, M Vendruscolo, A Cavalli
Journal of Computational Chemistry
(2014)
35
(doi: 10.1002/jcc.23588)
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour.
G Fusco, A De Simone, T Gopinath, V Vostrikov, M Vendruscolo, CM Dobson, G Veglia
Nat Commun
(2014)
5
(doi: 10.1038/ncomms4827)
The amyloid state and its association with protein misfolding diseases.
TPJ Knowles, M Vendruscolo, CM Dobson
Nat Rev Mol Cell Biol
(2014)
15
(doi: 10.1038/nrm3810)
Direct Observations of Amyloid β Self-Assembly in Live Cells Provide Insights into Differences in the Kinetics of Aβ(1–40) and Aβ(1–42) Aggregation
EK Esbjörner, F Chan, E Rees, M Erdelyi, LM Luheshi, CW Bertoncini, CF Kaminski, CM Dobson, GS Kaminski Schierle
Chemistry & Biology
(2014)
21
(doi: 10.1016/j.chembiol.2014.03.014)
Asymptotic solutions of the Oosawa model for the length distribution of biofilaments
TCT Michaels, GA Garcia, TPJ Knowles
The Journal of Chemical Physics
(2014)
140
(doi: 10.1063/1.4875897)
Iterative derivation of effective potentials to sample the conformational space of proteins at atomistic scale.
R Capelli, C Paissoni, P Sormanni, G Tiana
The Journal of Chemical Physics
(2014)
140
(doi: 10.1063/1.4876219)
Yusuf Hamied Department of Chemistry
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enquiries@ch.cam.ac.uk
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