Centre for Misfolding Diseases

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  • Currently displaying 1301 - 1320 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Highlights from the 49th EUCHEM Conference on Stereochemistry, Bürgenstock, Switzerland, May 2014
GJL Bernardes, AL Lawrence
Chemical communications (Cambridge, England)
(2014)
50
(doi: 10.1039/c4cc90250e)
Toxicity of protein oligomers is rationalized by a function combining size and surface hydrophobicity.
B Mannini, E Mulvihill, C Sgromo, R Cascella, R Khodarahmi, M Ramazzotti, CM Dobson, C Cecchi, F Chiti
ACS Chem Biol
(2014)
9
(doi: 10.1021/cb500505m)
Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain.
F Blombach, H Launay, APL Snijders, V Zorraquino, H Wu, B de Koning, SJJ Brouns, TJG Ettema, C Camilloni, A Cavalli, M Vendruscolo, MJ Dickman, LD Cabrita, A La Teana, D Benelli, P Londei, J Christodoulou, J van der Oost
Biochemical Journal
(2014)
462
(doi: 10.1042/BJ20131474)
Carbon‐Monoxide‐Releasing Molecules for the Delivery of Therapeutic CO In Vivo
S García-Gallego, GJL Bernardes
Angewandte Chemie International Edition
(2014)
53
(doi: 10.1002/anie.201311225)
Easyworm: An open-source software tool to determine the mechanical properties of worm-like chains
G Lamour, JB Kirkegaard, H Li, TP Knowles, J Gsponer
Source code for biology and medicine
(2014)
9
(doi: 10.1186/1751-0473-9-16)
Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism.
C Camilloni, AB Sahakyan, MJ Holliday, NG Isern, F Zhang, EZ Eisenmesser, M Vendruscolo
Proceedings of the National Academy of Sciences
(2014)
111
(doi: 10.1073/pnas.1404220111)
Statistical Mechanics of the Denatured State of a Protein Using Replica-Averaged Metadynamics
C Camilloni, M Vendruscolo
Journal of the American Chemical Society
(2014)
136
(doi: 10.1021/ja5027584)
Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides.
G Meisl, X Yang, E Hellstrand, B Frohm, JB Kirkegaard, SIA Cohen, CM Dobson, S Linse, TPJ Knowles
Proceedings of the National Academy of Sciences
(2014)
111
(doi: 10.1073/pnas.1401564111)
Self‐Assembly of Amyloid Fibrils That Display Active Enzymes
X Zhou, A Entwistle, H Zhang, AP Jackson, TO Mason, U Shimanovich, TPJ Knowles, AT Smith, EB Sawyer, S Perrett
ChemCatChem
(2014)
6
(doi: 10.1002/cctc.201402125)
A tensor-free method for the structural and dynamical refinement of proteins using residual dipolar couplings
C Camilloni, M Vendruscolo
The journal of physical chemistry. B
(2014)
119
(doi: 10.1021/jp5021824)
Role of filament annealing in the kinetics and thermodynamics of nucleated polymerization.
TCT Michaels, TPJ Knowles
The Journal of chemical physics
(2014)
140
(doi: 10.1063/1.4880121)
ALMOST: An all atom molecular simulation toolkit for protein structure determination
B Fu, AB Sahakyan, C Camilloni, GG Tartaglia, E Paci, A Caflisch, M Vendruscolo, A Cavalli
Journal of Computational Chemistry
(2014)
35
(doi: 10.1002/jcc.23588)
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour.
G Fusco, A De Simone, T Gopinath, V Vostrikov, M Vendruscolo, CM Dobson, G Veglia
Nature Communications
(2014)
5
(doi: 10.1038/ncomms4827)
The amyloid state and its association with protein misfolding diseases
TPJ Knowles, M Vendruscolo, CM Dobson
Nature reviews. Molecular cell biology
(2014)
15
(doi: 10.1038/nrm3810)
Direct Observations of Amyloid β Self-Assembly in Live Cells Provide Insights into Differences in the Kinetics of Aβ(1-40) and Aβ(1-42) Aggregation
EK Esbjörner, F Chan, E Rees, M Erdelyi, LM Luheshi, CW Bertoncini, CF Kaminski, CM Dobson, GS Kaminski Schierle
Chemistry & biology
(2014)
21
(doi: 10.1016/j.chembiol.2014.03.014)
Asymptotic solutions of the Oosawa model for the length distribution of biofilaments.
TCT Michaels, GA Garcia, TPJ Knowles
The Journal of Chemical Physics
(2014)
140
(doi: 10.1063/1.4875897)
Iterative derivation of effective potentials to sample the conformational space of proteins at atomistic scale.
R Capelli, C Paissoni, P Sormanni, G Tiana
J Chem Phys
(2014)
140
(doi: 10.1063/1.4876219)
Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation.
AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, S Linse, CM Dobson
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1315346111)
Hypochlorite-induced structural modifications enhance the chaperone activity of human α2-macroglobulin
AR Wyatt, JR Kumita, RW Mifsud, CA Gooden, MR Wilson, CM Dobson
Proceedings of the National Academy of Sciences
(2014)
111
(doi: 10.1073/pnas.1403379111)
Mean-field master equation formalism for biofilament growth
TCT Michaels, TPJ Knowles
American Journal of Physics
(2014)
82
(doi: 10.1119/1.4870004)
Yusuf Hamied Department of Chemistry
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