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Currently displaying 1301 - 1320 of 2455 publications

Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein.

S Gianni, C Camilloni, R Giri, A Toto, D Bonetti, A Morrone, P Sormanni, M Brunori, M Vendruscolo

Proc Natl Acad Sci U S A

(2014)

111

14141

(doi: 10.1073/pnas.1405233111)

Interaction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (Aβ42) aggregates leads to sub-stoichiometric inhibition of amyloid formation

C Månsson, P Arosio, R Hussein, HH Kampinga, RM Hashem, WC Boelens, CM Dobson, TPJ Knowles, S Linse, C Emanuelsson

The Journal of biological chemistry

(2014)

289

31066

(doi: 10.1074/jbc.m114.595124)

Identification and characterization of PKCγ, a kinase associated with SCA14, as an amyloidogenic protein

H Takahashi, N Adachi, T Shirafuji, S Danno, T Ueyama, M Vendruscolo, AN Shuvaev, T Sugimoto, T Seki, D Hamada, K Irie, H Hirai, N Sakai, N Saito

Human molecular genetics

(2014)

525

(doi: 10.1093/hmg/ddu472)

Equilibrium simulations of proteins using molecular fragment replacement and NMR chemical shifts.

W Boomsma, P Tian, J Frellsen, J Ferkinghoff-Borg, T Hamelryck, K Lindorff-Larsen, M Vendruscolo

Proceedings of the National Academy of Sciences of the United States of America

(2014)

111

13852

(doi: 10.1073/pnas.1404948111)

NMR characterization of the conformational fluctuations of the human lymphocyte function-associated antigen-1 I-domain.

HTA Leung, P Kukic, C Camilloni, F Bemporad, A De Simone, FA Aprile, JR Kumita, M Vendruscolo

Protein science : a publication of the Protein Society

(2014)

1596

(doi: 10.1002/pro.2538)

Antibodies and protein misfolding: From structural research tools to therapeutic strategies

E De Genst, A Messer, CM Dobson

Biochimica Et Biophysica Acta Proteins and Proteomics

(2014)

1844

1907

(doi: 10.1016/j.bbapap.2014.08.016)

The physical chemistry of the amyloid phenomenon: thermodynamics and kinetics of filamentous protein aggregation

AK Buell, CM Dobson, TPJ Knowles

Essays Biochem

(2014)

(doi: 10.1042/BSE0560011)

Highlights from the 49th EUCHEM Conference on Stereochemistry, Bürgenstock, Switzerland, May 2014

GJL Bernardes, AL Lawrence

Chem Commun (Camb)

(2014)

10752

(doi: 10.1039/c4cc90250e)

Toxicity of protein oligomers is rationalized by a function combining size and surface hydrophobicity

B Mannini, E Mulvihill, C Sgromo, R Cascella, R Khodarahmi, M Ramazzotti, CM Dobson, C Cecchi, F Chiti

ACS Chemical Biology

(2014)

2309

(doi: 10.1021/cb500505m)

Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain

F Blombach, H Launay, APL Snijders, V Zorraquino, H Wu, B de Koning, SJJ Brouns, TJG Ettema, C Camilloni, A Cavalli, M Vendruscolo, MJ Dickman, LD Cabrita, A La Teana, D Benelli, P Londei, J Christodoulou, J van der Oost

Biochem J

(2014)

462

373

(doi: 10.1042/BJ20131474)

Carbon‐Monoxide‐Releasing Molecules for the Delivery of Therapeutic CO In Vivo

S García-Gallego, GJL Bernardes

Angew Chem Int Ed Engl

(2014)

9712

(doi: 10.1002/anie.201311225)

Cysteine-Selective Reactions for Antibody Conjugation