Centre for Misfolding Diseases

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  • Currently displaying 1281 - 1300 of 2489 publications
Author(s)
Publication title
Journal Name
Publication year
Parmbsc1: a refined force field for DNA simulations.
I Ivani, PD Dans, A Noy, A Pérez, I Faustino, A Hospital, J Walther, P Andrio, R Goñi, A Balaceanu, G Portella, F Battistini, JL Gelpí, C González, M Vendruscolo, CA Laughton, SA Harris, DA Case, M Orozco
Nature Methods
(2015)
13
(doi: 10.1038/NMETH.3658)
Structure-Free Validation of Residual Dipolar Coupling and Paramagnetic Relaxation Enhancement Measurements of Disordered Proteins
FN Newby, A De Simone, M Yagi-Utsumi, X Salvatella, CM Dobson, M Vendruscolo
Biochemistry
(2015)
54
(doi: 10.1021/acs.biochem.5b00670)
Solvent exposure of Tyr10 as a probe of structural differences between monomeric and aggregated forms of the amyloid-β peptide.
P Aran Terol, JR Kumita, SC Hook, CM Dobson, EK Esbjörner
Biochem Biophys Res Commun
(2015)
468
(doi: 10.1016/j.bbrc.2015.11.018)
SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation.
R Zeineddine, JF Pundavela, L Corcoran, EM Stewart, D Do-Ha, M Bax, G Guillemin, KL Vine, DM Hatters, H Ecroyd, CM Dobson, BJ Turner, L Ooi, MR Wilson, NR Cashman, JJ Yerbury
Molecular neurodegeneration
(2015)
10
(doi: 10.1186/s13024-015-0053-4)
ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function.
T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, AR Costa, RB Dodd, FTS Chan, CH Michel, D Kronenberg-Versteeg, Y Li, S-P Yang, Y Wakutani, W Meadows, RR Ferry, L Dong, GG Tartaglia, G Favrin, W-L Lin, DW Dickson, M Zhen, D Ron, G Schmitt-Ulms, PE Fraser, NA Shneider, C Holt, M Vendruscolo, CF Kaminski, P St George-Hyslop
Neuron
(2015)
88
(doi: 10.1016/j.neuron.2015.10.030)
Mapping the Protein Fold Universe Using the CamTube Force Field in Molecular Dynamics Simulations.
P Kukic, A Kannan, MJJ Dijkstra, S Abeln, C Camilloni, M Vendruscolo
PLoS computational biology
(2015)
11
(doi: 10.1371/journal.pcbi.1004435)
The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments.
D Granata, F Baftizadeh, J Habchi, C Galvagnion, A De Simone, C Camilloni, A Laio, M Vendruscolo
Scientific Reports
(2015)
5
(doi: 10.1038/srep15449)
The length distribution of frangible biofilaments
TCT Michaels, P Yde, JCW Willis, MH Jensen, D Otzen, CM Dobson, AK Buell, TPJ Knowles
Journal of Chemical Physics
(2015)
143
(doi: 10.1063/1.4933230)
ChemInform Abstract: Biophysical Approaches for the Study of Interactions Between Molecular Chaperones and Protein Aggregates
MA Wright, FA Aprile, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
ChemInform
(2015)
46
(doi: 10.1002/chin.201545294)
Sulfur-Limonene Polysulfide: A Material Synthesized Entirely from Industrial By-Products and Its Use in Removing Toxic Metals from Water and Soil
MP Crockett, AM Evans, MJH Worthington, IS Albuquerque, AD Slattery, CT Gibson, JA Campbell, DA Lewis, GJL Bernardes, JM Chalker
Angewandte Chemie International Edition
(2015)
55
(doi: 10.1002/anie.201508708)
Abstract B35: Targeting the N-myc oncoprotein using nanobody technology
L Kent, C Dobson, E de-Genst, H Laman
Molecular Cancer Research
(2015)
13
(doi: 10.1158/1557-3125.myc15-b35)
Particle-based simulations of steady-state mass transport at high Péclet numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
(2015)
Particle-based simulations of steady-state mass transport at high Péclet numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
(2015)
(doi: 10.48550/arxiv.1510.05126)
Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity
EV Yates, T Müller, L Rajah, EJ De Genst, P Arosio, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
Nature Chemistry
(2015)
7
(doi: 10.1038/nchem.2344)
Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the a-synuclein-elicited immune response
A Labrador-Garrido, M Cejudo-Guillén, S Daturpalli, MM Leal, R Klippstein, EJ De Genst, J Villadiego, JJ Toledo-Aral, CM Dobson, SE Jackson, D Pozo, C Roodveldt
FASEB Journal
(2015)
30
(doi: 10.1096/fj.15-275131)
Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
PROTEIN SCIENCE
(2015)
24
Conformational Effects of the A21G Flemish Mutation on the Aggregation of Amyloid β Peptide
M Yagi-Utsumi, CM Dobson
Biol Pharm Bull
(2015)
38
(doi: 10.1248/bpb.b15-00466)
Sizing and interactions of proteins under native conditions from microfluidic diffusion measurements: application to molecular chaperones and single-step immunoassay
P Arosio, T Mueller, L Rajah, F Aprile, T Scheidt, J Carrozza, M Wright, M Vendruscolo, C Dobson, T Knowles
PROTEIN SCIENCE
(2015)
24
Structure and dynamics of intrinsically disordered proteins
B Fu, M Vendruscolo
Advances in experimental medicine and biology
(2015)
870
(doi: 10.1007/978-3-319-20164-1_2)
Druggability of intrinsically disordered proteins
P Joshi, M Vendruscolo
Adv Exp Med Biol
(2015)
870
(doi: 10.1007/978-3-319-20164-1_13)
Yusuf Hamied Department of Chemistry
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