Centre for Misfolding Diseases

Publications

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  • Currently displaying 1241 - 1260 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
The influence of novel gemini surfactants containing cycloalkyl side-chains on the structural phases of DNA in solution.
Z Pietralik, JR Kumita, CM Dobson, M Kozak
Colloids and Surfaces B: Biointerfaces
(2015)
131
(doi: 10.1016/j.colsurfb.2015.04.042)
Preventing peptide and protein misbehavior
P Arosio, G Meisl, M Andreasen, TPJ Knowles
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1505170112)
Investigating the mechanisms of amylolysis of starch granules by solution-state NMR.
AJ Baldwin, DL Egan, FJ Warren, PD Barker, CM Dobson, PJ Butterworth, PR Ellis
Biomacromolecules
(2015)
16
(doi: 10.1021/acs.biomac.5b00190)
Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
SW Chen, S Drakulic, E Deas, MM Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, GE De, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1421204112.)
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.
SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, EJ De-Genst, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1421204112)
Folic acid-tagged protein nanoemulsions loaded with CORM-2 enhance the survival of mice bearing subcutaneous A20 lymphoma tumors.
A Loureiro, GJL Bernardes, U Shimanovich, MP Sárria, E Nogueira, A Preto, AC Gomes, A Cavaco-Paulo
Nanomedicine Nanotechnology Biology and Medicine
(2015)
11
(doi: 10.1016/j.nano.2015.02.022)
Structure and dynamics of the integrin LFA-1 I-domain in the inactive state underlie its inside-out/outside-in signaling and allosteric mechanisms
P Kukic, HT Alvin Leung, F Bemporad, FA Aprile, JR Kumita, A De Simone, C Camilloni, M Vendruscolo
Structure (London, England : 1993)
(2015)
23
(doi: 10.1016/j.str.2014.12.020)
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers.
SIA Cohen, P Arosio, J Presto, FR Kurudenkandy, H Biverstål, L Dolfe, C Dunning, X Yang, B Frohm, M Vendruscolo, J Johansson, CM Dobson, A Fisahn, TPJ Knowles, S Linse
Nature structural & molecular biology
(2015)
22
(doi: 10.1038/nsmb.2971)
The physical basis of protein misfolding disorders
TPJ Knowles, M Vendruscolo, CM Dobson
Physics Today
(2015)
68
(doi: 10.1063/pt.3.2719)
The s2D method: Simultaneous sequence-based prediction of the statistical populations of ordered and disordered regions in proteins
P Sormanni, C Camilloni, P Fariselli, M Vendruscolo
Journal of Molecular Biology
(2015)
427
(doi: 10.1016/j.jmb.2014.12.007)
Chaperoned amyloid proteins for immune manipulation: α‐Synuclein/Hsp70 shifts immunity toward a modulatory phenotype
A Labrador-Garrido, M Cejudo-Guillén, R Klippstein, EJ De Genst, L Tomas-Gallardo, MM Leal, J Villadiego, JJ Toledo-Aral, CM Dobson, D Pozo, C Roodveldt
Immunity, inflammation and disease
(2015)
2
(doi: 10.1002/iid3.39)
Advances in chemical protein modification
O Boutureira, GJL Bernardes
Chemical reviews
(2015)
115
(doi: 10.1021/cr500399p)
The CamSol method of rational design of protein mutants with enhanced solubility
P Sormanni, FA Aprile, M Vendruscolo
Journal of Molecular Biology
(2015)
427
(doi: 10.1016/j.jmb.2014.09.026)
Protein Microgels from Amyloid Fibril Networks
U Shimanovich, I Efimov, TO Mason, P Flagmeier, AK Buell, A Gedanken, S Linse, KS Åkerfeldt, CM Dobson, DA Weitz, TPJ Knowles
ACS nano
(2015)
9
(doi: 10.1021/nn504869d)
Analysis of the hierarchical structure of the B. subtilis transcriptional regulatory network
S Kumar, M Vendruscolo, A Singh, D Kumar, A Samal
Molecular Omics
(2015)
11
(doi: 10.1039/c4mb00298a)
Structure of a low-population intermediate state in the release of an enzyme product
A De Simone, FA Aprile, A Dhulesia, CM Dobson, M Vendruscolo
Elife
(2015)
4
(doi: 10.7554/eLife.02777)
A high power-density, mediator-free, microfluidic biophotovoltaic device for cyanobacterial cells
P Bombelli, T Müller, TW Herling, CJ Howe, TPJ Knowles
Advanced Energy Materials
(2015)
5
(doi: 10.1002/aenm.201401299)
Thioflavin-T: application for α-synuclein aggregation kinetics
IM van der Wateren, AK Buell, C Galvagnion, EV Yates, CM Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
Functionalized protein nanoemulsions by incorporation of chemically modified BSA
A Loureiro, AS Abreu, MP Sárria, MCO Figueiredo, LM Saraiva, GJL Bernardes, AC Gomes, A Cavaco-Paulo
Rsc Advances
(2015)
5
(doi: 10.1039/c4ra13802c)
Kinetics of protein aggregation
TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2015)
44
Yusuf Hamied Department of Chemistry
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