Centre for Misfolding Diseases

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  • Currently displaying 1241 - 1260 of 2523 publications
Author(s)
Publication title
Journal Name
Publication year
Physical determinants of the self-replication of protein fibrils.
A Šarić, AK Buell, G Meisl, TCT Michaels, CM Dobson, S Linse, TPJ Knowles, D Frenkel
Nature physics
(2016)
12
(doi: 10.1038/NPHYS3828)
Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregation
P Flagmeier, G Meisl, M Vendruscolo, TPJ Knowles, CM Dobson, AK Buell, C Galvagnion
Proceedings of the National Academy of Sciences of the United States of America
(2016)
113
(doi: 10.1073/pnas.1604645113)
Metadynamic metainference: Enhanced sampling of the metainference ensemble using metadynamics
M Bonomi, C Camilloni, M Vendruscolo
Scientific reports
(2016)
6
(doi: 10.1038/srep31232)
Protein Aggregate-Ligand Binding Assays Based on Microfluidic Diffusional Separation
Y Zhang, AK Buell, T Müller, E De Genst, J Benesch, CM Dobson, TPJ Knowles
Chembiochem : a European journal of chemical biology
(2016)
17
(doi: 10.1002/cbic.201600384)
Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells.
A Drews, J Flint, N Shivji, P Jönsson, D Wirthensohn, E De Genst, C Vincke, S Muyldermans, C Dobson, D Klenerman
Scientific reports
(2016)
6
(doi: 10.1038/srep31910)
Controlling the Physical Dimensions of Peptide Nanotubes by Supramolecular Polymer Coassembly.
L Adler-Abramovich, P Marco, ZA Arnon, RCG Creasey, TCT Michaels, A Levin, DJ Scurr, CJ Roberts, TPJ Knowles, SJB Tendler, E Gazit
ACS Nano
(2016)
10
(doi: 10.1021/acsnano.6b01587)
Determination of statistical ensembles of intrinsically disordered proteins using NMR measurements
M Vendruscolo
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2016)
252
Characterizing the free energy landscape of intrinsically disordered proteins by metadynamics simulation and experiments
D Granata, G Zerze, J Mittal, M Vendruscolo, A Laio
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2016)
252
A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer's disease.
R Freer, P Sormanni, G Vecchi, P Ciryam, CM Dobson, M Vendruscolo
Science advances
(2016)
2
(doi: 10.1126/sciadv.1600947)
Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody.
EMS Fernández, CD Navo, N Martínez-Sáez, R Gonçalves-Pereira, VJ Somovilla, A Avenoza, JH Busto, GJL Bernardes, G Jiménez-Osés, F Corzana, JMG Fernández, CO Mellet, JM Peregrina
Organic Letters
(2016)
18
(doi: 10.1021/acs.orglett.6b01899)
Symptoms and patient factors associated with longer time to diagnosis for colorectal cancer: Results from a prospective cohort study
FM Walter, JD Emery, S Mendonca, N Hall, HC Morris, K Mills, C Dobson, C Bankhead, M Johnson, GA Abel, MD Rutter, W Hamilton, GP Rubin
Br J Cancer
(2016)
115
(doi: 10.1038/bjc.2016.221)
Towards a structural biology of the hydrophobic effect in protein folding
C Camilloni, D Bonetti, A Morrone, R Giri, CM Dobson, M Brunori, S Gianni, M Vendruscolo
Sci Rep
(2016)
6
(doi: 10.1038/srep28285)
The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity
V Crippa, ME Cicardi, N Ramesh, SJ Seguin, M Ganassi, I Bigi, C Diacci, E Zelotti, M Baratashvili, JM Gregory, CM Dobson, C Cereda, UB Pandey, A Poletti, S Carra
Human Molecular Genetics
(2016)
25
(doi: 10.1093/hmg/ddw232)
Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform.
TO Mason, TCT Michaels, A Levin, E Gazit, CM Dobson, AK Buell, TPJ Knowles
Journal of the American Chemical Society
(2016)
138
(doi: 10.1021/jacs.6b04136)
Quantification of the Relative Contributions of Loss-offunction and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies
R Cascella, C Capitini, G Fani, CM Dobson, C Cecchi, F Chiti
The Journal of biological chemistry
(2016)
291
(doi: 10.1074/jbc.M116.737726)
Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation (vol 7, pg 5052, 2016)
H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois
Chemical science
(2016)
7
(doi: 10.1039/c6sc90045c)
Unveiling (-)-EnglerinA as a Modulator of L-Type Calcium Channels
T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes
Angewandte Chemie (International ed. in English)
(2016)
55
(doi: 10.1002/anie.201604336)
Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms
M Iljina, GA Garcia, AJ Dear, J Flint, P Narayan, TCT Michaels, CM Dobson, D Frenkel, TPJ Knowles, D Klenerman
Scientific reports
(2016)
6
(doi: 10.1038/srep28658)
Quantifying Measurement Fluctuations from Stochastic Surface Processes on Sensors with Heterogeneous Sensitivity
J Charmet, TCT Michaels, R Daly, A Prasad, P Thiruvenkathanathan, RS Langley, TPJ Knowles, AA Seshia
Physical Review Applied
(2016)
5
(doi: 10.1103/physrevapplied.5.064016)
Fluctuations in the Kinetics of Linear Protein Self-Assembly
TCT Michaels, AJ Dear, JB Kirkegaard, KL Saar, DA Weitz, TPJ Knowles
Physical Review Letters
(2016)
116
(doi: 10.1103/PhysRevLett.116.258103)
Yusuf Hamied Department of Chemistry
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