Centre for Misfolding Diseases

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  • Currently displaying 1021 - 1040 of 2393 publications
Author(s)
Publication title
Journal Name
Publication year
Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method
FA Aprile, P Sormanni, M Perni, P Arosio, S Linse, TPJ Knowles, CM Dobson, M Vendruscolo
Science advances
(2017)
3
(doi: 10.1126/sciadv.1700488)
Direct Conversion of an Enzyme from Native-like to Amyloid-like Aggregates within Inclusion Bodies.
F Elia, F Cantini, F Chiti, CM Dobson, F Bemporad
Biophys J
(2017)
112
(doi: 10.1016/j.bpj.2017.05.011)
Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication.
A Munke, J Persson, T Weiffert, E De Genst, G Meisl, P Arosio, A Carnerup, CM Dobson, M Vendruscolo, TPJ Knowles, S Linse
Proc Natl Acad Sci U S A
(2017)
114
(doi: 10.1073/pnas.1700407114)
Self-assembled Protein Fibril-metal Oxide Nanocomposites
A Levin, TO Mason, TPJ Knowles, U Shimanovich
Israel Journal of Chemistry
(2017)
57
(doi: 10.1002/ijch.201600118)
Corrigendum: A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages
MMA Pereira, I Mahú, E Seixas, N Martinéz-Sánchez, N Kubasova, RM Pirzgalska, P Cohen, MO Dietrich, M López, GJL Bernardes, AI Domingos
Nature Communications
(2017)
8
(doi: 10.1038/ncomms15673)
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade.
F Chiti, CM Dobson
Annu Rev Biochem
(2017)
86
(doi: 10.1146/annurev-biochem-061516-045115)
Frontispiece: Site-Selective Modification of Proteins with Oxetanes
O Boutureira, N Martínez‐Sáez, KM Brindle, AA Neves, F Corzana, GJL Bernardes
Chemistry - A European Journal
(2017)
23
(doi: 10.1002/chem.201782762)
Structural basis of synaptic vesicle assembly promoted by α-synuclein (vol 7, 12563, 2016)
G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, GSK Schierle, M Vendruscolo, G Veglia, CM Dobson, A De Simone
Nat Commun
(2017)
8
(doi: 10.1038/ncomms15667)
Structural Characterization of the Early Events in the Nucleation–Condensation Mechanism in a Protein Folding Process
P Kukic, Y Pustovalova, C Camilloni, S Gianni, DM Korzhnev, M Vendruscolo
J Am Chem Soc
(2017)
139
(doi: 10.1021/jacs.7b01540)
Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TPJ Knowles, S Gandhi, CM Dobson, D Klenerman
Angewandte Chemie
(2017)
129
(doi: 10.1002/ange.201700966)
Protein modification: Via alkyne hydrosilylation using a substoichiometric amount of ruthenium(II) catalyst
TT-L Kwan, O Boutureira, EC Frye, SJ Walsh, MK Gupta, S Wallace, Y Wu, F Zhang, HF Sore, WRJD Galloway, JW Chin, M Welch, GJL Bernardes, DR Spring
Chemical science
(2017)
8
(doi: 10.1039/c6sc05313k)
Site‐Selective Modification of Proteins with Oxetanes
O Boutureira, N Martínez-Sáez, KM Brindle, AA Neves, F Corzana, GJ Lopes Bernardes
Chemistry - A European Journal
(2017)
23
(doi: 10.1002/chem.201700745)
Modulation of electrostatic interactions to reveal a reaction network unifying the aggregation behaviour of the Aβ42 peptide and its variants
G Meisl, X Yang, CM Dobson, S Linse, TPJ Knowles
Chemical Science
(2017)
8
(doi: 10.1039/c7sc00215g)
The rnf168 paralog rnf169 defines a new class of ubiquitylated histone reader involved in the response to dna damage
J Kitevski-LeBlanc, A Fradet-Turcotte, P Kukic, MD Wilson, G Portella, T Yuwen, S Panier, S Duan, MD Canny, H van Ingen, CH Arrowsmith, JL Rubinstein, M Vendruscolo, D Durocher, LE Kay
Elife
(2017)
6
(doi: 10.7554/elife.23872)
Emergence and evolution of an interaction between intrinsically disordered proteins
G Hultqvist, E Åberg, C Camilloni, GN Sundell, E Andersson, J Dogan, CN Chi, M Vendruscolo, P Jemth
Elife
(2017)
6
(doi: 10.7554/elife.16059)
Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS.
P Ciryam, IA Lambert-Smith, DM Bean, R Freer, F Cid, GG Tartaglia, DN Saunders, MR Wilson, SG Oliver, RI Morimoto, CM Dobson, M Vendruscolo, G Favrin, JJ Yerbury
Proceedings of the National Academy of Sciences of USA
(2017)
114
(doi: 10.1073/pnas.1613854114)
Intra-chain organisation of hydrophobic residues controls inter-chain aggregation rates of amphiphilic polymers
P Varilly, AP Willard, JB Kirkegaard, TPJ Knowles, D Chandler
The Journal of chemical physics
(2017)
146
(doi: 10.1063/1.4977932)
A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages.
MMA Pereira, I Mahú, E Seixas, N Martinéz-Sánchez, N Kubasova, RM Pirzgalska, P Cohen, MO Dietrich, M López, GJL Bernardes, AI Domingos
Nature Communications
(2017)
8
(doi: 10.1038/ncomms14967)
MOAG-4 promotes the aggregation of α-synuclein by competing with self-protective electrostatic interactions
Y Yoshimura, MA Holmberg, P Kukic, CB Andersen, A Mata-Cabana, SF Falsone, M Vendruscolo, EAA Nollen, FAA Mulder
The Journal of biological chemistry
(2017)
292
(doi: 10.1074/jbc.M116.764886)
Simultaneous quantification of protein order and disorder.
P Sormanni, D Piovesan, GT Heller, M Bonomi, P Kukic, C Camilloni, M Fuxreiter, Z Dosztanyi, RV Pappu, MM Babu, S Longhi, P Tompa, AK Dunker, VN Uversky, SCE Tosatto, M Vendruscolo
Nat Chem Biol
(2017)
13
(doi: 10.1038/nchembio.2331)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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