Centre for Misfolding Diseases

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  • Currently displaying 1021 - 1040 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation.
F aprile, E Källstig, G Limorenko, Vendruscolo, D Ron, C hansen
Scientific Reports
(2017)
7
(doi: 10.1038/s41598-017-08324-z)
Rapid and accurate in silico solubility screening of a monoclonal antibody library.
P Sormanni, L Amery, S Ekizoglou, M Vendruscolo, B Popovic
Scientific Reports
(2017)
7
(doi: 10.1038/s41598-017-07800-w)
Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates.
S Chia, P Flagmeier, J Habchi, V Lattanzi, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences
(2017)
114
(doi: 10.1073/pnas.1700239114)
Silk micrococoons for protein stabilisation and molecular encapsulation
U Shimanovich, FS Ruggeri, E De Genst, J Adamcik, TP Barros, D Porter, T Müller, R Mezzenga, CM Dobson, F Vollrath, C Holland, TPJ Knowles
Nat Commun
(2017)
8
(doi: 10.1038/ncomms15902)
The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis
MA Hanspal, CM Dobson, JJ Yerbury, JR Kumita
Biochimica Et Biophysica Acta Molecular Basis of Disease
(2017)
1863
(doi: 10.1016/j.bbadis.2017.07.007)
The contribution of biophysical and structural studies of protein self-assembly to the design of therapeutic strategies for amyloid diseases.
N Cremades, CM Dobson
Neurobiology of Disease
(2017)
109
(doi: 10.1016/j.nbd.2017.07.009)
Protein homeostasis of a metastable subproteome associated with Alzheimer's disease
R Kundra, P Ciryam, RI Morimoto, CM Dobson, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2017)
114
(doi: 10.1073/pnas.1618417114)
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species
D Klenerman, M Iljina, L Hong, MH Horrocks, MH Ludtmann, ML Choi, CD Hughes, FS Ruggeri, T Guilliams, AK Buell, J-E Lee, S Gandhi, SF Lee, CE Bryant, M Vendruscolo, TPJ Knowles, CM Dobson, E De Genst, D Klenerman
BMC Biology
(2017)
15
(doi: 10.1186/s12915-017-0390-6)
Inverse electron demand Diels-Alder reactions in chemical biology
GJ Lopes Bernardes, BL Oliveira, Z Guo
Chemical Society reviews
(2017)
46
(doi: 10.1039/c7cs00184c)
Amyloid-like Fibrils from an α-Helical Transmembrane Protein.
K Stroobants, JR Kumita, NJ Harris, DY Chirgadze, CM Dobson, PJ Booth, M Vendruscolo
Biochemistry
(2017)
56
(doi: 10.1021/acs.biochem.7b00157)
Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TPJ Knowles, S Gandhi, CM Dobson, D Klenerman
Angew Chem Int Ed Engl
(2017)
56
(doi: 10.1002/anie.201700966)
Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method
FA Aprile, P Sormanni, M Perni, P Arosio, S Linse, TPJ Knowles, CM Dobson, M Vendruscolo
Science advances
(2017)
3
(doi: 10.1126/sciadv.1700488)
Direct Conversion of an Enzyme from Native-like to Amyloid-like Aggregates within Inclusion Bodies.
F Elia, F Cantini, F Chiti, CM Dobson, F Bemporad
Biophys J
(2017)
112
(doi: 10.1016/j.bpj.2017.05.011)
Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication
A Munke, J Persson, T Weiffert, E De Genst, G Meisl, P Arosio, A Carnerup, CM Dobson, M Vendruscolo, TPJ Knowles, S Linse
Proc Natl Acad Sci U S A
(2017)
114
(doi: 10.1073/pnas.1700407114)
Self‐assembled Protein Fibril‐metal Oxide Nanocomposites
A Levin, TO Mason, TPJ Knowles, U Shimanovich
Israel Journal of Chemistry
(2017)
57
(doi: 10.1002/ijch.201600118)
Corrigendum: A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages
MMA Pereira, I Mahú, E Seixas, N Martinéz-Sánchez, N Kubasova, RM Pirzgalska, P Cohen, MO Dietrich, M López, GJL Bernardes, AI Domingos
Nat Commun
(2017)
8
(doi: 10.1038/ncomms15673)
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
F Chiti, CM Dobson
Annual Review of Biochemistry
(2017)
86
(doi: 10.1146/annurev-biochem-061516-045115)
Corrigendum: Structural basis of synaptic vesicle assembly promoted by α-synuclein
G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, GSK Schierle, M Vendruscolo, G Veglia, CM Dobson, A De Simone
Nature communications
(2017)
8
(doi: 10.1038/ncomms15667)
Frontispiece: Site‐Selective Modification of Proteins with Oxetanes
O Boutureira, N Martínez‐Sáez, KM Brindle, AA Neves, F Corzana, GJL Bernardes
Chemistry - A European Journal
(2017)
23
(doi: 10.1002/chem.201782762)
Structural Characterization of the Early Events in the Nucleation-Condensation Mechanism in a Protein Folding Process.
P Kukic, Y Pustovalova, C Camilloni, S Gianni, DM Korzhnev, M Vendruscolo
J Am Chem Soc
(2017)
139
(doi: 10.1021/jacs.7b01540)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
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enquiries@ch.cam.ac.uk
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