Centre for Misfolding Diseases

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  • Currently displaying 1001 - 1020 of 2338 publications
Author(s)
Publication title
Journal Name
Publication year
Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells
A Drews, J Flint, N Shivji, P Jönsson, D Wirthensohn, E De Genst, C Vincke, S Muyldermans, C Dobson, D Klenerman
Scientific Reports
(2016)
6
(doi: 10.1038/srep31910)
Controlling the Physical Dimensions of Peptide Nanotubes by Supramolecular Polymer Coassembly.
L Adler-Abramovich, P Marco, ZA Arnon, RCG Creasey, TCT Michaels, A Levin, DJ Scurr, CJ Roberts, TPJ Knowles, SJB Tendler, E Gazit
ACS nano
(2016)
10
(doi: 10.1021/acsnano.6b01587)
A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer's disease.
R Freer, P Sormanni, G Vecchi, P Ciryam, CM Dobson, M Vendruscolo
Sci Adv
(2016)
2
(doi: 10.1126/sciadv.1600947)
Tn Antigen Mimics Based on sp 2‑Iminosugars with Affinity for an anti-MUC1 Antibody
EMS Fernández, CD Navo, N Martínez-Sáez, R Gonçalves-Pereira, VJ Somovilla, A Avenoza, JH Busto, GJL Bernardes, G Jiménez-Osés, F Corzana, JMG Fernández, CO Mellet, JM Peregrina
Org Lett
(2016)
18
(doi: 10.1021/acs.orglett.6b01899)
Symptoms and patient factors associated with longer time to diagnosis for colorectal cancer: results from a prospective cohort study
FM Walter, JD Emery, S Mendonca, N Hall, HC Morris, K Mills, C Dobson, C Bankhead, M Johnson, GA Abel, MD Rutter, W Hamilton, GP Rubin
British journal of cancer
(2016)
115
(doi: 10.1038/bjc.2016.221)
Towards a structural biology of the hydrophobic effect in protein folding
C Camilloni, D Bonetti, A Morrone, R Giri, CM Dobson, M Brunori, S Gianni, M Vendruscolo
Scientific Reports
(2016)
6
(doi: 10.1038/srep28285)
The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity
V Crippa, ME Cicardi, N Ramesh, SJ Seguin, M Ganassi, I Bigi, C Diacci, E Zelotti, M Baratashvili, JM Gregory, CM Dobson, C Cereda, UB Pandey, A Poletti, S Carra
Human molecular genetics
(2016)
25
(doi: 10.1093/hmg/ddw232)
Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform.
TO Mason, TCT Michaels, A Levin, E Gazit, CM Dobson, AK Buell, TPJ Knowles
J Am Chem Soc
(2016)
138
(doi: 10.1021/jacs.6b04136)
Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies.
R Cascella, C Capitini, G Fani, CM Dobson, C Cecchi, F Chiti
Journal of Biological Chemistry
(2016)
291
(doi: 10.1074/jbc.M116.737726)
Correction: Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation.
H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois
Chemical Science
(2016)
7
(doi: 10.1039/c6sc90045c)
Unveiling (-)-Englerin A as a Modulator of L-Type Calcium Channels.
T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes
Angew Chem Int Ed Engl
(2016)
55
(doi: 10.1002/anie.201604336)
Quantifying Measurement Fluctuations from Stochastic Surface Processes on Sensors with Heterogeneous Sensitivity
J Charmet, TCT Michaels, R Daly, A Prasad, P Thiruvenkathanathan, RS Langley, TPJ Knowles, AA Seshia
Physical Review Applied
(2016)
5
(doi: 10.1103/PhysRevApplied.5.064016)
Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms.
M Iljina, GA Garcia, AJ Dear, J Flint, P Narayan, TCT Michaels, CM Dobson, D Frenkel, TPJ Knowles, D Klenerman
Scientific Reports
(2016)
6
(doi: 10.1038/srep28658)
Fluctuations in the Kinetics of Linear Protein Self-Assembly
TCT Michaels, AJ Dear, JB Kirkegaard, KL Saar, DA Weitz, TPJ Knowles
Phys Rev Lett
(2016)
116
(doi: 10.1103/PhysRevLett.116.258103)
Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation.
H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois
Chem Sci
(2016)
7
(doi: 10.1039/c6sc01520d)
Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
C Galvagnion, JWP Brown, MM Ouberai, P Flagmeier, M Vendruscolo, AK Buell, E Sparr, CM Dobson
Proc Natl Acad Sci U S A
(2016)
113
(doi: 10.1073/pnas.1601899113)
Structure of a low-population binding intermediate in protein-RNA recognition.
AN Borkar, MF Bardaro, C Camilloni, FA Aprile, G Varani, M Vendruscolo
Proc Natl Acad Sci U S A
(2016)
113
(doi: 10.1073/pnas.1521349113)
Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity.
G Fusco, A De Simone, P Arosio, M Vendruscolo, G Veglia, CM Dobson
Scientific Reports
(2016)
6
(doi: 10.1038/srep27125)
Particle-Based Monte-Carlo Simulations of Steady-State Mass Transport at Intermediate Péclet Numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
International Journal of Nonlinear Sciences and Numerical Simulation
(2016)
17
(doi: 10.1515/ijnsns-2015-0056)
Structural Effects of Two Camelid Nanobodies Directed to Distinct C-Terminal Epitopes on α-Synuclein
F El-Turk, FN Newby, E De Genst, T Guilliams, T Sprules, A Mittermaier, CM Dobson, M Vendruscolo
Biochemistry
(2016)
55
(doi: 10.1021/acs.biochem.6b00149)
Yusuf Hamied Department of Chemistry
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