Centre for Misfolding Diseases

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  • Currently displaying 1001 - 1020 of 2508 publications
Author(s)
Publication title
Journal Name
Publication year
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in C. elegans
C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, T Sinnige, MC Lechler, N Schlörit, RF Laine, CH Michel, M Vendruscolo, CF Kaminski, GSK Schierle, DC David
(2018)
(doi: 10.1101/417873)
Fast fluorescence lifetime imaging reveals the aggregation processes of α-synuclein and polyglutamine in aging Caenorhabditis elegans
RF Laine, T Sinnige, K Yu, AJ Haack, C Poudel, P Gaida, N Curry, M Perni, EAA Nollen, CM Dobson, M Vendruscolo, GSK Schierle, CF Kaminski
(2018)
(doi: 10.1101/414714)
Systematic mapping of free energy landscapes of a growing filamin domain during biosynthesis.
CA Waudby, T Wlodarski, M-E Karyadi, AME Cassaignau, SHS Chan, AS Wentink, JM Schmidt-Engler, C Camilloni, M Vendruscolo, LD Cabrita, J Christodoulou
Proceedings of the National Academy of Sciences of the United States of America
(2018)
115
(doi: 10.1073/pnas.1716252115)
Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution
D Klenerman
Anal Chem
(2018)
90
(doi: 10.1021/acs.analchem.8b02226)
A method for partitioning the information contained in a protein sequence between its structure and function.
A Possenti, M Vendruscolo, C Camilloni, G Tiana
Proteins Structure Function and Bioinformatics
(2018)
86
(doi: 10.1002/prot.25527)
Identification of oxidative stress in red blood cells with nanoscale chemical resolution by infrared nanospectroscopy
FS Ruggeri, C Marcott, S Dinarelli, G Longo, M Girasole, G Dietler, TPJ Knowles
International Journal of Molecular Sciences
(2018)
19
(doi: 10.3390/ijms19092582)
Discovery of 2,4-dimethoxypyridines as novel autophagy inhibitors
L Robke, T Rodrigues, P Schröder, DJ Foley, GJL Bernardes, L Laraia, H Waldmann
Tetrahedron
(2018)
74
(doi: 10.1016/j.tet.2018.07.021)
DNA-Coated Functional Oil Droplets.
A Caciagli, M Zupkauskas, A Levin, TPJ Knowles, C Mugemana, N Bruns, T O'Neill, WJ Frith, E Eiser
Langmuir : the ACS journal of surfaces and colloids
(2018)
34
(doi: 10.1021/acs.langmuir.8b01828)
Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates
MJ Matos, C Labão-Almeida, C Sayers, O Dada, M Tacke, GJL Bernardes
Chemistry – A European Journal
(2018)
24
(doi: 10.1002/chem.201800872)
Self-Assembly-Mediated Release of Peptide Nanoparticles through Jets Across Microdroplet Interfaces.
A Levin, TCT Michaels, TO Mason, T Müller, L Adler-Abramovich, L Mahadevan, ME Cates, E Gazit, TPJ Knowles
ACS Applied Materials & Interfaces
(2018)
10
(doi: 10.1021/acsami.8b09511)
Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson’s disease model
D Chatterjee, M Bhatt, D Butler, E De Genst, CM Dobson, A Messer, JH Kordower
npj Parkinson's Disease
(2018)
4
(doi: 10.1038/s41531-018-0062-4)
Obituary: Nico van Nuland 1961–2017
A Matagne, CM Dobson
Eur Biophys J
(2018)
47
(doi: 10.1007/s00249-018-1326-y)
The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity
M Jamshad, TJ Knowles, SA White, DG Ward, F Mohammed, K Rahman, GW Hughes, G Kramer, B Bukau, D Huber
(2018)
(doi: 10.1101/389460)
Evidence for phospholipid export from the gram-negative inner membrane: time to rethink the Mla pathway?
GW Hughes, SCL Hall, CS Laxton, P Sridhar, AH Mahadi, C Hatton, TJ Piggot, M Jamshad, V Spana, CT Ian, C Harding, GL Isom, J Bryant, RJ Parr, Y Yakub, M Jeeves, D Huber, HR Ian, LA Clifton, LL Andrew, TJ Knowles
(2018)
(doi: 10.1101/388546)
Structural Ensemble Modulation upon Small-Molecule Binding to Disordered Proteins
GT Heller, M Bonomi, M Vendruscolo
Journal of Molecular Biology
(2018)
430
(doi: 10.1016/j.jmb.2018.03.015)
Combining Affinity Selection and Specific Ion Mobility for Microchip Protein Sensing
WE Arter, J Charmet, J Kong, KL Saar, TW Herling, T Müller, UF Keyser, TPJ Knowles
Analytical Chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b02051)
Author Correction: The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation
FA Aprile, E Källstig, G Limorenko, M Vendruscolo, D Ron, C Hansen
Scientific reports
(2018)
8
(doi: 10.1038/s41598-018-29893-7)
Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery.
M Perni, PK Challa, JB Kirkegaard, R Limbocker, M Koopman, MC Hardenberg, P Sormanni, T Müller, KL Saar, LWY Roode, J Habchi, G Vecchi, N Fernando, S Casford, EAA Nollen, M Vendruscolo, CM Dobson, TPJ Knowles
Journal of neuroscience methods
(2018)
306
(doi: 10.1016/j.jneumeth.2018.02.005)
Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation.
C Månsson, RTP van Cruchten, U Weininger, X Yang, R Cukalevski, P Arosio, CM Dobson, T Knowles, M Akke, S Linse, C Emanuelsson
Biochemistry
(2018)
57
(doi: 10.1021/acs.biochem.8b00353)
Structural differences between toxic and nontoxic HypF-N oligomers.
C Capitini, JR Patel, A Natalello, C D'Andrea, A Relini, JA Jarvis, L Birolo, A Peduzzo, M Vendruscolo, P Matteini, CM Dobson, A De Simone, F Chiti
Chem Commun (Camb)
(2018)
54
(doi: 10.1039/c8cc03446j)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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