Centre for Misfolding Diseases

Publications

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  • Currently displaying 1001 - 1020 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model
J Villadiego, A Labrador-Garrido, JM Franco, M Leal-Lasarte, EJ De Genst, CM Dobson, D Pozo, JJ Toledo-Aral, C Roodveldt
Glia
(2017)
66
(doi: 10.1002/glia.23237)
Thermodynamics of Polypeptide Supramolecular Assembly in the Short-Chain Limit
TO Mason, TCT Michaels, A Levin, CM Dobson, E Gazit, TPJ Knowles, AK Buell
J Am Chem Soc
(2017)
139
(doi: 10.1021/jacs.7b00229)
Targeting the N-myc oncoprotein using nanobody technology
L Kent
(2017)
(doi: 10.17863/CAM.25345)
Nanoscale click-reactive scaffolds from peptide self-assembly
APM Guttenplan, LJ Young, D Matak-Vinkovic, CF Kaminski, TPJ Knowles, LS Itzhaki
J Nanobiotechnology
(2017)
15
(doi: 10.1186/s12951-017-0300-7)
Kinetic constraints on self-assembly into closed supramolecular structures
TCT Michaels, MMJ Bellaiche, MF Hagan, TPJ Knowles
Scientific Reports
(2017)
7
(doi: 10.1038/s41598-017-12528-8)
Gradient-free determination of isoelectric points of proteins on chip.
U Łapińska, KL Saar, EV Yates, TW Herling, T Müller, PK Challa, CM Dobson, T Knowles
Physical Chemistry Chemical Physics
(2017)
19
(doi: 10.1039/c7cp01503h)
Systematic mapping of the free energy landscapes of a growing immunoglobulin domain identifies a kinetic intermediate associated with co-translational proline isomerization
CA Waudby, M-E Karyadi, T Wlodarski, AME Cassaignau, S Chan, JM Schmidt-Engler, AS Wentink, C Camilloni, M Vendruscolo, LD Cabrita, J Christodoulou
(2017)
(doi: 10.1101/189050)
Sequential Release of Proteins from Structured Multishell Microcapsules.
U Shimanovich, TCT Michaels, E De Genst, D Matak-Vinkovic, CM Dobson, TPJ Knowles
Biomacromolecules
(2017)
18
(doi: 10.1021/acs.biomac.7b00351)
Paratope Prediction using Convolutional and Recurrent Neural Networks
E Liberis, P Veličković, P Sormanni, M Vendruscolo, P Liò
(2017)
(doi: 10.1101/185488)
Nickel-Catalyzed Azide-Alkyne Cycloaddition To Access 1,5-Disubstituted 1,2,3-Triazoles in Air and Water
WG Kim, ME Kang, JB Lee, MH Jeon, S Lee, J Lee, B Choi, PMSD Cal, S Kang, J-M Kee, GJL Bernardes, J-U Rohde, W Choe, SY Hong
Journal of the American Chemical Society
(2017)
139
(doi: 10.1021/jacs.7b06338)
Methods of probing the interactions between small molecules and disordered proteins
GT Heller, FA Aprile, M Vendruscolo
Cellular and Molecular Life Sciences
(2017)
74
(doi: 10.1007/s00018-017-2563-4)
Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide
GT Heller, FA Aprile, M Bonomi, C Camilloni, A De Simone, M Vendruscolo
Journal of Molecular Biology
(2017)
429
(doi: 10.1016/j.jmb.2017.07.016)
Scaling behaviour and rate-determining steps in filamentous self-assembly.
G Meisl, L Rajah, SAI Cohen, M Pfammatter, A Šarić, E Hellstrand, AK Buell, A Aguzzi, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
Chem Sci
(2017)
8
(doi: 10.1039/c7sc01965c)
The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation
F aprile, E Källstig, G Limorenko, Vendruscolo, D Ron, C hansen
Scientific reports
(2017)
7
(doi: 10.1038/s41598-017-08324-z)
Rapid and accurate in silico solubility screening of a monoclonal antibody library.
P Sormanni, L Amery, S Ekizoglou, M Vendruscolo, B Popovic
Scientific Reports
(2017)
7
(doi: 10.1038/s41598-017-07800-w)
Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates.
S Chia, P Flagmeier, J Habchi, V Lattanzi, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences
(2017)
114
(doi: 10.1073/pnas.1700239114)
Silk micrococoons for protein stabilisation and molecular encapsulation.
U Shimanovich, FS Ruggeri, E De Genst, J Adamcik, TP Barros, D Porter, T Müller, R Mezzenga, CM Dobson, F Vollrath, C Holland, TPJ Knowles
Nat Commun
(2017)
8
(doi: 10.1038/ncomms15902)
The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis
MA Hanspal, CM Dobson, JJ Yerbury, JR Kumita
Biochim Biophys Acta Mol Basis Dis
(2017)
1863
(doi: 10.1016/j.bbadis.2017.07.007)
The contribution of biophysical and structural studies of protein self-assembly to the design of therapeutic strategies for amyloid diseases.
N Cremades, CM Dobson
Neurobiology of disease
(2017)
109
(doi: 10.1016/j.nbd.2017.07.009)
Protein homeostasis of a metastable subproteome associated with Alzheimer's disease
R Kundra, P Ciryam, RI Morimoto, CM Dobson, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2017)
114
(doi: 10.1073/pnas.1618417114)
Yusuf Hamied Department of Chemistry
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