Centre for Misfolding Diseases

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  • Currently displaying 981 - 1000 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism.
VE Zwicker, BL Oliveira, JH Yeo, ST Fraser, GJL Bernardes, EJ New, KA Jolliffe
Angewandte Chemie International Edition
(2018)
58
(doi: 10.1002/anie.201812489)
A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging.
BJ Stenton, BL Oliveira, MJ Matos, L Sinatra, GJL Bernardes
Chem Sci
(2018)
9
(doi: 10.1039/c8sc00256h)
Microfluidic Diffusional Sizing Enables Characterisation of Protein-Protein Interactions Under Native Conditions
S Devenish, C Thorne, T Scheidt, J Carozza, P Arosio, Y Zhang, A Buell, T Mueller, A Lynn, J Faherty, M Wright, M Butz, T Knowles
PROTEIN SCIENCE
(2018)
27
Microfluidic approaches for probing amyloid assembly and behaviour.
TW Herling, A Levin, KL Saar, CM Dobson, TPJ Knowles
Lab Chip
(2018)
18
(doi: 10.1039/c7lc01241a)
Fast Fluorescence Lifetime Imaging for Longitudinal Studies of Protein Aggregation in Living C. Elegans
T Sinnige, RF Laine, KY Ma, AJ Haack, P Gaida, N Curry, M Perni, EAA Nollen, CM Dobson, M Vendruscolo, GSK Schierle, CF Kaminski
BIOPHYSICAL JOURNAL
(2018)
114
On-chip measurements of protein unfolding from direct observations of micron-scale diffusion
Y Zhang, EV Yates, L Hong, KL Saar, G Meisl, CM Dobson, TPJ Knowles
Chemical Science
(2018)
9
(doi: 10.1039/c7sc04331g)
Microfluidics for Protein Biophysics
J Charmet, P Arosio, TPJ Knowles
J Mol Biol
(2017)
430
(doi: 10.1016/j.jmb.2017.12.015)
The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer
VJ Somovilla, IA Bermejo, IS Albuquerque, N Martínez-Sáez, J Castro-López, F García-Martín, I Compañón, H Hinou, S Nishimura, J Jiménez-Barbero, JL Asensio, A Avenoza, JH Busto,, R Hurtado-Guerrero, JM Peregrina, GJ Lopes Bernardes, F Corzana1
J Am Chem Soc
(2017)
139
(doi: 10.1021/jacs.7b09447)
Structural basis of membrane disruption and cellular toxicity by a-synuclein oligomers
G Fusco, SW Chen, PTF Williamson, R Cascella, M Perni, JA Jarvis, C Cecchi, M Vendruscolo, F Chiti, N Cremades, L Ying, CM Dobson, A De Simone
Science
(2017)
358
(doi: 10.1126/science.aan6160)
Chemoselective Installation of Amine Bonds on Proteins Through Aza-Michael Ligation
AM Freedy, MJ Matos, O Boutureira, F Corzana, A Guerreiro, P Akkapeddi, VJ Somovilla, T Rodrigues, K Nicholls, B Xie, G Jiménez-Osés, KM Brindle, AA Neves, GJL Bernardes
Journal of the American Chemical Society
(2017)
139
(doi: 10.1021/jacs.7b10702)
Inhibiting the Ca2+ influx induced by human CSF
A Drews, S De, P Flagmeier, DC Wirthensohn, W-H Chen, DR Whiten, M Rodrigues, C Vincke, S Muyldermans, RW Paterson, CF Slattery, NC Fox, JM Schott, H Zetterberg, CM Dobson, S Gandhi, D Klenerman
Cell reports
(2017)
21
(doi: 10.1016/j.celrep.2017.11.057)
Precise Probing of Residue Roles by Post-Translational β,γ-C,N Aza-Michael Mutagenesis in Enzyme Active Sites
J Dadová, K-J Wu, PG Isenegger, JC Errey, GJL Bernardes, JM Chalker, L Raich, C Rovira, BG Davis
ACS Central Science
(2017)
3
(doi: 10.1021/acscentsci.7b00341)
Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
N Martínez-Sáez, S Sun, D Oldrini, P Sormanni, O Boutureira, F Carboni, I Compañón, MJ Deery, M Vendruscolo, F Corzana, R Adamo, GJ Lopes Bernardes
Angewandte Chemie - International Edition
(2017)
56
(doi: 10.1002/anie.201708847)
Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
N Martínez‐Sáez, S Sun, D Oldrini, P Sormanni, O Boutureira, F Carboni, I Compañón, MJ Deery, M Vendruscolo, F Corzana, R Adamo, GJL Bernardes
Angewandte Chemie
(2017)
129
(doi: 10.1002/ange.201708847)
Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy
M Bonomi, R Pellarin, M Vendruscolo
(2017)
(doi: 10.1101/219972)
MobiDB 3.0: More annotations for intrinsic disorder, conformational diversity and interactions in proteins
D Piovesan, F Tabaro, L Paladin, M Necci, I Micetic, C Camilloni, N Davey, Z Dosztányi, B Mészáros, AM Monzon, G Parisi, E Schad, P Sormanni, P Tompa, M Vendruscolo, WF Vranken, SCE Tosatto
Nucleic Acids Research
(2017)
46
(doi: 10.1093/nar/gkx1071)
Delivery of Native Proteins into C. Elegans Using a Transduction Protocol Based on Lipid Vesicles
M Perni, FA Aprile, S Casford, B Mannini, P Sormanni, CM Dobson, M Vendruscolo
Scientific Reports
(2017)
7
(doi: 10.1038/s41598-017-13755-9)
Clusterin protects neurons against intracellular proteotoxicity.
JM Gregory, DR Whiten, RA Brown, TP Barros, JR Kumita, JJ Yerbury, S Satapathy, K McDade, C Smith, LM Luheshi, CM Dobson, MR Wilson
Acta Neuropathologica Communications
(2017)
5
(doi: 10.1186/s40478-017-0481-1)
Application of Lysine-specific Labeling to Detect Transient Interactions Present During Human Lysozyme Amyloid Fibril Formation.
M Ahn, CA Waudby, A Bernardo-Gancedo, E De Genst, A Dhulesia, X Salvatella, J Christodoulou, CM Dobson, JR Kumita
Scientific Reports
(2017)
7
(doi: 10.1038/s41598-017-14739-5)
Enhanced Permeability and Binding Activity of Isobutylene-Grafted Peptides
S Sun, I Compañón, N Martínez-Sáez, JD Seixas, O Boutureira, F Corzana, GJL Bernardes
Chembiochem
(2017)
19
(doi: 10.1002/cbic.201700586)
Yusuf Hamied Department of Chemistry
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