Centre for Misfolding Diseases

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  • Currently displaying 981 - 1000 of 2524 publications
Author(s)
Publication title
Journal Name
Publication year
De novo design of potent and selective mimics of IL-2 and IL-15.
D-A Silva, S Yu, UY Ulge, JB Spangler, KM Jude, C Labão-Almeida, LR Ali, A Quijano-Rubio, M Ruterbusch, I Leung, T Biary, SJ Crowley, E Marcos, CD Walkey, BD Weitzner, F Pardo-Avila, J Castellanos, L Carter, L Stewart, SR Riddell, M Pepper, GJL Bernardes, M Dougan, KC Garcia, D Baker
Nature
(2019)
565
(doi: 10.1038/s41586-018-0830-7)
Effects of α-tubulin acetylation on microtubule structure and stability
L Eshun-Wilson, R Zhang, D Portran, M Nachury, D Toso, T Lohr, M Vendruscolo, M Bonomi, JS Fraser, E Nogales
(2019)
(doi: 10.1101/516591)
Physical determinants of amyloid assembly in biofilm formation
M Andreasen, G Meisl, JD Taylor, TCT Michaels, A Levin, DE Otzen, MR Chapman, CM Dobson, SJ Matthews, TPJ Knowles
Mbio
(2019)
10
(doi: 10.1128/mBio.02279-18)
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y-C Liao, M Fernandopulle, G Wang, H Choi, L Hao, CM Drerup, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, M Nelson, M Czekalska, G Musteikyte, R Patel, C Stephens, A Pasolli, L Forrest, P St George-Hyslop, J Lippincott-Schwartz, ME Ward
(2019)
(doi: 10.2139/ssrn.3312723)
Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent
MJ Matos, G Jiménez-Osés, GJL Bernardes
Methods Mol Biol
(2019)
2033
(doi: 10.1007/978-1-4939-9654-4_3)
Analysis of αb-crystallin polydispersity in solution through native microfluidic electrophoresis
MA Wright, FS Ruggeri, KL Saar, PK Challa, JLP Benesch, TPJ Knowles
Analyst
(2019)
144
(doi: 10.1039/C9AN00382G)
Efficient and irreversible antibody-cysteine bioconjugation using carbonylacrylic reagents
B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ACB Burtoloso, G Jiménez-Osés, F Corzana, GJL Bernardes
Nature Protocols
(2019)
14
(doi: 10.1038/s41596-018-0083-9)
Oligomer Diversity during the Aggregation of the Repeat Region of Tau
M Kjaergaard, AJ Dear, F Kundel, S Qamar, G Meisl, TPJ Knowles, D Klenerman
ACS Chem Neurosci
(2018)
9
(doi: 10.1021/acschemneuro.8b00250)
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions
B Mannini, J Habchi, S Chia, FS Ruggeri, M Perni, TPJ Knowles, CM Dobson, M Vendruscolo
ACS chemical neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00141)
Resolving protein mixtures using microfluidic diffusional sizing combined with synchrotron radiation circular dichroism.
C Bortolini, T Kartanas, D Copic, I Condado Morales, Y Zhang, PK Challa, Q Peter, T Jávorfi, R Hussain, M Dong, G Siligardi, TPJ Knowles, J Charmet
Lab Chip
(2018)
19
(doi: 10.1039/c8lc00757h)
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology.
H Fu, A Possenti, R Freer, Y Nakano, NC Hernandez Villegas, M Tang, PVM Cauhy, BA Lassus, S Chen, SL Fowler, HY Figueroa, ED Huey, GVW Johnson, M Vendruscolo, KE Duff
Nature neuroscience
(2018)
22
(doi: 10.1038/s41593-018-0298-7)
Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming
N Ahmed, P Sormanni, P Ciryam, M Vendruscolo, CM Dobson, EP O’Brien
(2018)
(doi: 10.1101/490755)
One-pot stapling of interchain disulfides of antibodies using an isobutylene motif.
S Sun, P Akkapeddi, MC Marques, N Martínez-Sáez, VM Torres, C Cordeiro, O Boutureira, GJL Bernardes
Org Biomol Chem
(2018)
17
(doi: 10.1039/c8ob02877j)
Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale.
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
Nano Lett
(2018)
18
(doi: 10.1021/acs.nanolett.8b02916)
Protein engineering through chemical, genetic and computational manipulation
I Hamachi, GJL Bernardes
Chemical Society reviews
(2018)
47
(doi: 10.1039/c8cs90125b)
Attentive Cross-Modal Paratope Prediction
A Deac, P VeliČković, P Sormanni
J Comput Biol
(2018)
26
(doi: 10.1089/cmb.2018.0175)
Image-Assisted Microvessel-on-a-Chip Platform for Studying Cancer Cell Transendothelial Migration Dynamics
C Bertulli, M Gerigk, N Piano, Y Liu, D Zhang, T Müller, TJ Knowles, YYS Huang
Scientific reports
(2018)
8
(doi: 10.1038/s41598-018-30776-0)
Bioorthogonal decaging reactions for targeted drug activation
S Davies, BJ Stenton, GJL Bernardes
Chimia (Aarau)
(2018)
72
(doi: 10.2533/chimia.2018.771)
Mechanobiology of Protein Droplets: Force Arises from Disorder.
TJ Welsh, Y Shen, A Levin, TPJ Knowles
Cell
(2018)
175
(doi: 10.1016/j.cell.2018.11.020)
Automated Behavioral Analysis of Large <em>C. elegans</em> Populations Using a Wide Field-of-view Tracking Platform
M Perni, S Casford, FA Aprile, EA Nollen, TPJ Knowles, M Vendruscolo, CM Dobson
Journal of Visualized Experiments
(2018)
(doi: 10.3791/58643-v)
Yusuf Hamied Department of Chemistry
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