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Currently displaying 961 - 980 of 2474 publications

Microfluidic Diffusional Sizing Enables Characterisation of Protein-Protein Interactions Under Native Conditions

S Devenish, C Thorne, T Scheidt, J Carozza, P Arosio, Y Zhang, A Buell, T Mueller, A Lynn, J Faherty, M Wright, M Butz, T Knowles

PROTEIN SCIENCE

(2018)

167

Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform

M Perni, S Casford, FA Aprile, EA Nollen, TPJ Knowles, M Vendruscolo, CM Dobson

Journal of visualized experiments : JoVE

(2018)

2018

e58643

(doi: 10.3791/58643)

Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling

M Bonomi, S Hanot, CH Greenberg, A Sali, M Nilges, M Vendruscolo, R Pellarin

Structure

(2018)

175

(doi: 10.1016/j.str.2018.09.011)

Posttranslational chemical mutagenesis: to reveal the role of non-catalytic cysteine residues in pathogenic bacterial phosphatases

JB Bertoldo, H Terenzi, S Hüttelmaier, GJL Bernardes

Biochemistry

(2018)

6144

(doi: 10.1021/acs.biochem.8b00639)

Statistical Mechanics of Globular Oligomer Formation by Protein Molecules

AJ Dear, A Šarić, TCT Michaels, CM Dobson, TPJ Knowles

The Journal of Physical Chemistry B

(2018)

122

11721

(doi: 10.1021/acs.jpcb.8b07805)

Direct Observation of Murine Prion Protein Replication in Vitro.

JC Sang, G Meisl, AM Thackray, L Hong, A Ponjavic, TPJ Knowles, R Bujdoso, D Klenerman

Journal of the American Chemical Society

(2018)

140

14789

(doi: 10.1021/jacs.8b08311)

¬Nanoscopic characterization of individual endogenous protein aggregates in human neuronal cells

DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M-G Spillantini, D Klenerman, MH Horrocks

Chembiochem

(2018)

2033

(doi: 10.1002/cbic.201800209)

INFLAMMATORY MYOPATHIES P.160A bioinformatics approach to define the aggregation capacity of the myofiber proteome in inclusion body myositis

C Weihl, P Ciryam, A Guttsches, K Marcus, R Morimoto, M Vendruscolo, R Kley

Neuromuscular Disorders

(2018)

S77

(doi: 10.1016/j.nmd.2018.06.188)

SAR by kinetics for drug discovery in protein misfolding diseases

S Chia, J Habchi, TCT Michaels, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo

Proceedings of the National Academy of Sciences

(2018)

115

10245

(doi: 10.1073/pnas.1807884115)

Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity.

FS Ruggeri, J Charmet, T Kartanas, Q Peter, S Chia, J Habchi, CM Dobson, M Vendruscolo, TPJ Knowles

Nature Communications

(2018)

3890

(doi: 10.1038/s41467-018-06345-4)

Solution fibre spinning technique for the fabrication of tuneable decellularised matrix-laden fibres and fibrous micromembranes

Z Li, J Tuffin, IM Lei, FS Ruggeri, NS Lewis, EL Gill, T Savin, L Huleihel, SF Badylak, T Knowles, SC Satchell, GI Welsh, MA Saleem, YYS Huang

Acta Biomaterialia

(2018)

111

(doi: 10.1016/j.actbio.2018.08.010)

Determination of the conformational states of strychnine using NMR residual dipolar couplings in a tensor-free approach

G Tomba, C Camilloni, M Vendruscolo

Methods

(2018)

148

(doi: 10.1016/j.ymeth.2018.07.005)

Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in C. elegans

C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, T Sinnige, MC Lechler, N Schlörit, RF Laine, CH Michel, M Vendruscolo, CF Kaminski, GSK Schierle, DC David

(2018)

(doi: 10.1101/417873)