Centre for Misfolding Diseases

Publications

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  • Currently displaying 961 - 980 of 2336 publications
Author(s)
Publication title
Journal Name
Publication year
Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning.
PK Challa, T Kartanas, J Charmet, TPJ Knowles
Biomicrofluidics
(2017)
11
(doi: 10.1063/1.4976690)
Single α-synuclein oligomers are hydrophobically distinct from mature fibrils
J-E Lee, MN Bongiovanni, M Rodrigues, CM Dobson, SF Lee, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Norbornene probes for the study of cysteine oxidation
LJ Alcock, KD Farrell, MT Akol, GH Jones, MM Tierney, HB Kramer, TL Pukala, GJL Bernardes, MV Perkins, JM Chalker
Tetrahedron
(2017)
74
(doi: 10.1016/j.tet.2017.11.011)
Structural characterisation of the early events in the nucleation-condensation mechanism of folding
P Kukic, Y Pustovalova, C Camilloni, S Gianni, DM Korzhnev, M Vendruscolo
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
In situcharacterization of advanced glycation end products (AGEs) in collagen and model extracellular matrix by solid state NMR
R Li, R Rajan, WCV Wong, DG Reid, MJ Duer, VJ Somovilla, N Martinez-Saez, GJL Bernardes, R Hayward, CM Shanahan
Chemical communications (Cambridge, England)
(2017)
53
(doi: 10.1039/c7cc06624d)
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease
J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proc Natl Acad Sci U S A
(2016)
114
(doi: 10.1073/pnas.1615613114)
Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping.
MN Bongiovanni, J Godet, MH Horrocks, L Tosatto, AR Carr, DC Wirthensohn, RT Ranasinghe, JV Fritz, CM Dobson, D Klenerman, SF Lee
Nature communications
(2016)
7
(doi: 10.1038/ncomms13544)
Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
The Journal of chemical physics
(2016)
145
(doi: 10.1063/1.4965040)
The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme
M Ahn, CL Hagan, A Bernardo-Gancedo, E De Genst, FN Newby, J Christodoulou, A Dhulesia, M Dumoulin, CV Robinson, CM Dobson, JR Kumita
Biophys J
(2016)
111
(doi: 10.1016/j.bpj.2016.10.028)
Micro- and nanoscale hierarchical structure of core-shell protein microgels.
LR Volpatti, U Shimanovich, FS Ruggeri, S Bolisetty, T Müller, TO Mason, TCT Michaels, R Mezzenga, G Dietler, TPJ Knowles
Journal of Materials Chemistry B
(2016)
4
(doi: 10.1039/c6tb02683d)
Trends in therapeutic drug conjugates for bacterial diseases: a patent review
PMSD Cal, MJ Matos, GJL Bernardes
Expert Opin Ther Pat
(2016)
27
(doi: 10.1080/13543776.2017.1259411)
Antibody-drug conjugates: The missing link
T Rodrigues, GJL Bernardes
Nature chemistry
(2016)
8
(doi: 10.1038/nchem.2685)
A Minimal, Unstrained S‐Allyl Handle for Pre‐Targeting Diels–Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez-Osés, GJL Bernardes
Angew Chem Int Ed Engl
(2016)
55
(doi: 10.1002/anie.201608438)
A Minimal, Unstrained S‐Allyl Handle for Pre‐Targeting Diels–Alder Bioorthogonal Labeling in Live Cells
BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez‐Osés, GJL Bernardes
Angewandte Chemie
(2016)
128
(doi: 10.1002/ange.201608438)
Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ.
DC Butler, SN Joshi, ED Genst, AS Baghel, CM Dobson, A Messer
PloS one
(2016)
11
(doi: 10.1371/journal.pone.0165964)
Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents
T Rodrigues, F Sieglitz, GJL Bernardes
Chemical Society reviews
(2016)
45
(doi: 10.1039/c5cs00916b)
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, WL Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, ML Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis
Science (New York, N.Y.)
(2016)
354
Dynamics of heteromolecular filament formation
AJ Dear, TCT Michaels, TPJ Knowles
Journal of Chemical Physics
(2016)
145
(doi: 10.1063/1.4966571)
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces.
JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, M Vendruscolo, TPJ Knowles, CM Dobson, C Galvagnion
Scientific Reports
(2016)
6
(doi: 10.1038/srep36010)
Structural Characteristics of α-Synuclein Oligomers.
N Cremades, SW Chen, CM Dobson
International Review of Cytology
(2016)
329
(doi: 10.1016/bs.ircmb.2016.08.010)
Yusuf Hamied Department of Chemistry
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