Centre for Misfolding Diseases

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  • Currently displaying 961 - 980 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
Optical Structural Analysis of Individual α-Synuclein Oligomers
JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, D Klenerman, SF Lee
Angew Chem Int Ed Engl
(2018)
57
(doi: 10.1002/anie.201710779)
Microfluidic Diffusion Platform for Characterizing the Sizes of Lipid Vesicles and the Thermodynamics of Protein–Lipid Interactions
H Gang, C Galvagnion, G Meisl, T Müller, M Pfammatter, AK Buell, A Levin, CM Dobson, B Mu, TPJ Knowles
Anal Chem
(2018)
90
(doi: 10.1021/acs.analchem.7b04820)
A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis
KR Scroggie, LJ Alcock, MJ Matos, GJL Bernardes, MV Perkins, JM Chalker
Peptide Science
(2018)
110
(doi: 10.1002/pep2.24069)
On-chip measurements of protein unfolding from direct observations of micron-scale diffusion.
Y Zhang, EV Yates, L Hong, KL Saar, G Meisl, CM Dobson, TPJ Knowles
Chemical Science
(2018)
9
(doi: 10.1039/c7sc04331g)
Third generation antibody discovery methods: in silico rational design.
P Sormanni, FA Aprile, M Vendruscolo
Chemical Society reviews
(2018)
47
(doi: 10.1039/c8cs00523k)
On-Chip Measurements of Membrane Protein Interactions
Y Zhang, T Knowles, S Linse
PROTEIN SCIENCE
(2018)
27
Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils
JWP Brown, G Meisl, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion
Chem Commun (Camb)
(2018)
54
(doi: 10.1039/c8cc03002b)
Stochastic calculus of protein filament formation under spatial confinement
TCT Michaels, AJ Dear, TPJ Knowles
NEW JOURNAL OF PHYSICS
(2018)
20
(doi: 10.1088/1367-2630/aac0bc)
Systematic Development of Small Molecules to Inhibit Specific Steps of α-Synuclein Aggregation in Parkinson's Disease
R Staats, P Flagmeier, M Vendruscolo
BIOPHYSICAL JOURNAL
(2018)
114
A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism.
VE Zwicker, BL Oliveira, JH Yeo, ST Fraser, GJL Bernardes, EJ New, KA Jolliffe
Angew Chem Int Ed Engl
(2018)
58
(doi: 10.1002/anie.201812489)
Microfluidic Diffusional Sizing Enables Characterisation of Protein-Protein Interactions Under Native Conditions
S Devenish, C Thorne, T Scheidt, J Carozza, P Arosio, Y Zhang, A Buell, T Mueller, A Lynn, J Faherty, M Wright, M Butz, T Knowles
PROTEIN SCIENCE
(2018)
27
Secondary nucleation in amyloid formation
M Törnquist, TCT Michaels, K Sanagavarapu, X Yang, G Meisl, SIA Cohen, TPJ Knowles, S Linse
Chemical Communications
(2018)
54
(doi: 10.1039/c8cc02204f)
Glaucoma as a protein misfolding disease: an investigation of its metastable proteome
P Joshi, M Vendruscolo
JOURNAL OF ALZHEIMERS DISEASE
(2018)
64
Observation of molecular self-assembly events in massively parallel microdroplet arrays.
Z Toprakcioglu, PK Challa, A Levin, TPJ Knowles
Lab on a chip
(2018)
18
(doi: 10.1039/c8lc00862k)
Enhancing power density of biophotovoltaics by decoupling storage and power delivery
KL Saar, P Bombelli, DJ Lea-Smith, T Call, E-M Aro, T Müller, CJ Howe, TPJ Knowles
Nature Energy
(2018)
3
(doi: 10.1038/s41560-017-0073-0)
Development of Antibody-Directed Therapies: Quo Vadis?
T Rodrigues, GJL Bernardes
Angew Chem Int Ed Engl
(2018)
57
(doi: 10.1002/anie.201712185)
A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging.
BJ Stenton, BL Oliveira, MJ Matos, L Sinatra, GJL Bernardes
Chem Sci
(2018)
9
(doi: 10.1039/c8sc00256h)
Microfluidic approaches for probing amyloid assembly and behaviour.
TW Herling, A Levin, KL Saar, CM Dobson, TPJ Knowles
Lab on a Chip
(2018)
18
(doi: 10.1039/c7lc01241a)
Fast Fluorescence Lifetime Imaging for Longitudinal Studies of Protein Aggregation in Living C. Elegans
T Sinnige, RF Laine, KY Ma, AJ Haack, P Gaida, N Curry, M Perni, EAA Nollen, CM Dobson, M Vendruscolo, GSK Schierle, CF Kaminski
BIOPHYSICAL JOURNAL
(2018)
114
Microfluidics for Protein Biophysics
J Charmet, P Arosio, TPJ Knowles
Journal of Molecular Biology
(2017)
430
(doi: 10.1016/j.jmb.2017.12.015)
Yusuf Hamied Department of Chemistry
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enquiries@ch.cam.ac.uk
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