Centre for Misfolding Diseases

Publications

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  • Currently displaying 941 - 960 of 2453 publications
Author(s)
Publication title
Journal Name
Publication year
A bioinformatics approach to define the aggregation capacity of the myofiber proteome in inclusion body myositis
C Weihl, P Ciryam, A Guttsches, K Marcus, R Morimoto, M Vendruscolo, R Kley
Neuromuscular Disorders
(2018)
28
(doi: 10.1016/j.nmd.2018.06.188)
SAR by kinetics for drug discovery in protein misfolding diseases
S Chia, J Habchi, TCT Michaels, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences
(2018)
115
(doi: 10.1073/pnas.1807884115)
Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity
FS Ruggeri, J Charmet, T Kartanas, Q Peter, S Chia, J Habchi, CM Dobson, M Vendruscolo, TPJ Knowles
Nature Communications
(2018)
9
(doi: 10.1038/s41467-018-06345-4)
Solution Fibre Spinning Technique for the Fabrication of Tuneable Decellularised Matrix-Laden Fibres and Fibrous Micromembranes
Z Li, J Tuffin, IM Lei, FS Ruggeri, NS Lewis, EL Gill, T Savin, L Huleihel, SF Badylak, T Knowles, SC Satchell, GI Welsh, MA Saleem, YYS Huang
Acta Biomaterialia
(2018)
78
(doi: 10.1016/j.actbio.2018.08.010)
Determination of the conformational states of strychnine using NMR residual dipolar couplings in a tensor-free approach
G Tomba, C Camilloni, M Vendruscolo
Methods
(2018)
148
(doi: 10.1016/j.ymeth.2018.07.005)
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in C. elegans
C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, T Sinnige, MC Lechler, N Schlörit, RF Laine, CH Michel, M Vendruscolo, CF Kaminski, GSK Schierle, DC David
(2018)
(doi: 10.1101/417873)
Fast fluorescence lifetime imaging reveals the aggregation processes of α-synuclein and polyglutamine in aging Caenorhabditis elegans
RF Laine, T Sinnige, K Yu, AJ Haack, C Poudel, P Gaida, N Curry, M Perni, EAA Nollen, CM Dobson, M Vendruscolo, GSK Schierle, CF Kaminski
(2018)
(doi: 10.1101/414714)
Systematic mapping of free energy landscapes of a growing filamin domain during biosynthesis.
CA Waudby, T Wlodarski, M-E Karyadi, AME Cassaignau, SHS Chan, AS Wentink, JM Schmidt-Engler, C Camilloni, M Vendruscolo, LD Cabrita, J Christodoulou
Proceedings of the National Academy of Sciences
(2018)
115
(doi: 10.1073/pnas.1716252115)
Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution
D Klenerman
Anal Chem
(2018)
90
(doi: 10.1021/acs.analchem.8b02226)
A method for partitioning the information contained in a protein sequence between its structure and function.
A Possenti, M Vendruscolo, C Camilloni, G Tiana
Proteins
(2018)
86
(doi: 10.1002/prot.25527)
Discovery of 2,4-dimethoxypyridines as novel autophagy inhibitors
L Robke, T Rodrigues, P Schröder, DJ Foley, GJL Bernardes, L Laraia, H Waldmann
Tetrahedron
(2018)
74
(doi: 10.1016/j.tet.2018.07.021)
Identification of Oxidative Stress in Red Blood Cells with Nanoscale Chemical Resolution by Infrared Nanospectroscopy.
FS Ruggeri, C Marcott, S Dinarelli, G Longo, M Girasole, G Dietler, TPJ Knowles
International journal of molecular sciences
(2018)
19
(doi: 10.3390/ijms19092582)
DNA-Coated Functional Oil Droplets
A Caciagli, M Zupkauskas, A Levin, TPJ Knowles, C Mugemana, N Bruns, T O'Neill, WJ Frith, E Eiser
Langmuir : the ACS journal of surfaces and colloids
(2018)
34
(doi: 10.1021/acs.langmuir.8b01828)
Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates
MJ Matos, C Labão-Almeida, C Sayers, O Dada, M Tacke, GJL Bernardes
Chemistry A European Journal
(2018)
24
(doi: 10.1002/chem.201800872)
Self-Assembly-Mediated Release of Peptide Nanoparticles through Jets Across Microdroplet Interfaces
A Levin, TCT Michaels, TO Mason, T Müller, L Adler-Abramovich, L Mahadevan, ME Cates, E Gazit, TPJ Knowles
ACS applied materials & interfaces
(2018)
10
(doi: 10.1021/acsami.8b09511)
Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson's disease model.
D Chatterjee, M Bhatt, D Butler, E De Genst, CM Dobson, A Messer, JH Kordower
NPJ Parkinson's disease
(2018)
4
(doi: 10.1038/s41531-018-0062-4)
Obituary: Nico van Nuland 1961-2017 OBITUARY
A Matagne, CM Dobson
Eur Biophys J
(2018)
47
(doi: 10.1007/s00249-018-1326-y)
Structural Ensemble Modulation upon Small-Molecule Binding to Disordered Proteins
GT Heller, M Bonomi, M Vendruscolo
Journal of Molecular Biology
(2018)
430
(doi: 10.1016/j.jmb.2018.03.015)
Combining Affinity Selection and Specific Ion Mobility for Microchip Protein Sensing.
WE Arter, J Charmet, J Kong, KL Saar, TW Herling, T Müller, UF Keyser, TPJ Knowles
Analytical chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b02051)
Author Correction: The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation.
FA Aprile, E Källstig, G Limorenko, M Vendruscolo, D Ron, C Hansen
Scientific reports
(2018)
8
(doi: 10.1038/s41598-018-29893-7)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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