Centre for Misfolding Diseases

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  • Currently displaying 941 - 960 of 2403 publications
Author(s)
Publication title
Journal Name
Publication year
Parapred: Antibody paratope prediction using convolutional and recurrent neural networks
E Liberis, P Velickovic, P Sormanni, M Vendruscolo, P Liò
Bioinformatics
(2018)
34
(doi: 10.1093/bioinformatics/bty305)
Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy.
M Bonomi, R Pellarin, M Vendruscolo
Biophys J
(2018)
114
(doi: 10.1016/j.bpj.2018.02.028)
Water‐Dispersible Polydopamine‐Coated Nanofibers for Stimulation of Neuronal Growth and Adhesion
S Sieste, T Mack, CV Synatschke, C Schilling, C Meyer Zu Reckendorf, L Pendi, S Harvey, FS Ruggeri, TPJ Knowles, C Meier, DYW Ng, T Weil, B Knöll
Advanced healthcare materials
(2018)
7
(doi: 10.1002/adhm.201701485)
Biophotonics of Native Silk Fibrils.
U Shimanovich, D Pinotsi, K Shimanovich, N Yu, S Bolisetty, J Adamcik, R Mezzenga, J Charmet, F Vollrath, E Gazit, CM Dobson, GK Schierle, C Holland, CF Kaminski, TPJ Knowles
Macromol Biosci
(2018)
18
(doi: 10.1002/mabi.201700295)
Molecular determinants of the interaction of EGCG with ordered and disordered proteins
G Fusco, M Sanz-Hernandez, FS Ruggeri, M Vendruscolo, CM Dobson, A De Simone
Biopolymers
(2018)
109
(doi: 10.1002/bip.23117)
Correction to ‘Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species’
L-M Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, M Rodrigues, CM Dobson, S Gandhi, SE Bohndiek, TN Snaddon, SF Lee
R Soc Open Sci
(2018)
5
(doi: 10.1098/rsos.180308)
Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading
F Kundel, L Hong, B Falcon, WA McEwan, TCT Michaels, G Meisl, N Esteras, AY Abramov, TJP Knowles, M Goedert, D Klenerman
ACS chemical neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00094)
Artificial Intelligence Recognizes β-Lapachone as an Allosteric 5- Lipoxygenase Inhibitor
G Bernardes, T Rodrigues, M Werner, J Roth, EHG da Cruz, MC Marques, SA Lobo, A Koeberle, F Corzana, E N. da Silva Júnior, O Werz
(2018)
(doi: 10.26434/chemrxiv.6026795.v1)
Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide.
SIA Cohen, R Cukalevski, TCT Michaels, A Šarić, M Törnquist, M Vendruscolo, CM Dobson, AK Buell, TPJ Knowles, S Linse
Nature chemistry
(2018)
10
(doi: 10.1038/s41557-018-0023-x)
Optical Structural Analysis of Individual α‐Synuclein Oligomers
JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, D Klenerman, SF Lee
Angewandte Chemie
(2018)
130
(doi: 10.1002/ange.201710779)
The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity.
D Cox, DR Whiten, JWP Brown, MH Horrocks, R San Gil, CM Dobson, D Klenerman, AM van Oijen, H Ecroyd
Journal of Biological Chemistry
(2018)
293
(doi: 10.1074/jbc.M117.813865)
Chemo- and Regioselective Lysine Modification on Native Proteins
MJ Matos, BL Oliveira, N Martínez-Sáez, A Guerreiro, PMSD Cal, J Bertoldo, M Maneiro, E Perkins, J Howard, MJ Deery, JM Chalker, F Corzana, G Jiménez-Osés, GJL Bernardes
J Am Chem Soc
(2018)
140
(doi: 10.1021/jacs.7b12874)
Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity.
F Kundel, S De, P Flagmeier, MH Horrocks, M Kjaergaard, SL Shammas, SE Jackson, CM Dobson, D Klenerman
ACS Chemical Biology
(2018)
13
(doi: 10.1021/acschembio.7b01039)
Reaction rate theory for supramolecular kinetics: application to protein aggregation
TCT Michaels, LX Liu, S Curk, PG Bolhuis, A Saric, TPJ Knowles
(2018)
(doi: 10.48550/arxiv.1803.04851)
Corneal Dystrophy Mutations Drive Pathogenesis by Targeting TGFBIp Stability and Solubility in a Latent Amyloid-forming Domain
M Stenvang, NP Schafer, KG Malmos, A-MW Pérez, O Niembro, P Sormanni, RV Basaiawmoit, G Christiansen, M Andreasen, DE Otzen
J Mol Biol
(2018)
430
(doi: 10.1016/j.jmb.2018.03.001)
Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation
TCT Michaels, A Šarić, J Habchi, S Chia, G Meisl, M Vendruscolo, CM Dobson, TPJ Knowles
Annual review of physical chemistry
(2018)
69
(doi: 10.1146/annurev-physchem-050317-021322)
Molecular dynamics ensemble refinement of the heterogeneous native state of NCBD using chemical shifts and NOEs
E Papaleo, C Camilloni, K Teilum, M Vendruscolo, K Lindorff-Larsen
(2018)
(doi: 10.1101/273714)
Additional contributions from: Nobel Symposium 162 - Microfluidics
S Löfås, AE Herr, J Qin, T Knowles, T Kitamori, H Lu, DJ Beebe, J Han, J Landers, A Manz, R Zengerle, DA Weitz, J Elf, T Laurell
(2018)
(doi: 10.48550/arxiv.1802.08565)
Antikörpergerichtete Therapien: Quo vadis?
T Rodrigues, GJL Bernardes
Angewandte Chemie
(2018)
130
(doi: 10.1002/ange.201712185)
Real-Time Intrinsic Fluorescence Visualization and Sizing of Proteins and Protein Complexes in Microfluidic Devices.
PK Challa, Q Peter, MA Wright, Y Zhang, KL Saar, JA Carozza, JLP Benesch, TPJ Knowles
Analytical Chemistry
(2018)
90
(doi: 10.1021/acs.analchem.7b04523)
Yusuf Hamied Department of Chemistry
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