Centre for Misfolding Diseases

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  • Currently displaying 941 - 960 of 2489 publications
Author(s)
Publication title
Journal Name
Publication year
Structure and Dynamics of Alzheimer's Associated Amyloid-Beta Peptide
T Löhr, K Kohlhoff, G Heller, M Vendruscolo
Biophysical Journal
(2019)
116
(doi: 10.1016/j.bpj.2018.11.2352)
Probing Specificity in Disordered Protein Interactions with Small Molecules using Integrative Methods
GT Heller, FA Aprile, M Bonomi, C Camilloni, A De Simone, M Vendruscolo
Biophysical Journal
(2019)
116
(doi: 10.1016/j.bpj.2018.11.998)
Targeting the Formation of Amyloid Oligomers using Rationally Designed Antibodies
FA Aprile, P Sormanni, M Perni, P Arosio, S Linse, TP Knowles, CM Dobson, M Vendruscolo
Biophysical Journal
(2019)
116
(doi: 10.1016/j.bpj.2018.11.196)
Atomic force microscopy for single molecule characterisation of protein aggregation
FS Ruggeri, T Šneideris, M Vendruscolo, TPJ Knowles
Archives of Biochemistry and Biophysics
(2019)
664
(doi: 10.1016/j.abb.2019.02.001)
A superposition free method for protein conformational ensemble analyses and local clustering based on a differential geometry representation of backbone
AM da Silva Neto, SR Silva, M Vendruscolo, C Camilloni, RW Montalvão
Proteins: Structure, Function, and Bioinformatics
(2019)
87
(doi: 10.1002/prot.25652)
In vitro and in silico assessment of the developability of a designed monoclonal antibody library
A-M Wolf Pérez, P Sormanni, JS Andersen, LI Sakhnini, I Rodriguez-Leon, JR Bjelke, AJ Gajhede, L De Maria, DE Otzen, M Vendruscolo, N Lorenzen
mAbs
(2019)
11
(doi: 10.1080/19420862.2018.1556082)
Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation.
M Ahn, BI Lee, S Chia, J Habchi, JR Kumita, M Vendruscolo, CM Dobson, CB Park
Chem Commun (Camb)
(2019)
55
(doi: 10.1039/c8cc09288e)
De novo design of potent and selective mimics of IL-2 and IL-15
D-A Silva, S Yu, UY Ulge, JB Spangler, KM Jude, C Labão-Almeida, LR Ali, A Quijano-Rubio, M Ruterbusch, I Leung, T Biary, SJ Crowley, E Marcos, CD Walkey, BD Weitzner, F Pardo-Avila, J Castellanos, L Carter, L Stewart, SR Riddell, M Pepper, GJL Bernardes, M Dougan, KC Garcia, D Baker
Nature
(2019)
565
(doi: 10.1038/s41586-018-0830-7)
Effects of α-tubulin acetylation on microtubule structure and stability
L Eshun-Wilson, R Zhang, D Portran, M Nachury, D Toso, T Lohr, M Vendruscolo, M Bonomi, JS Fraser, E Nogales
(2019)
(doi: 10.1101/516591)
Physical determinants of amyloid assembly in biofilm formation
M Andreasen, G Meisl, JD Taylor, TCT Michaels, A Levin, DE Otzen, MR Chapman, CM Dobson, SJ Matthews, TPJ Knowles
mBio
(2019)
10
(doi: 10.1128/mbio.02279-18)
Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ACB Burtoloso, G Jiménez-Osés, F Corzana, GJL Bernardes
Nat Protoc
(2019)
14
(doi: 10.1038/s41596-018-0083-9)
Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent.
MJ Matos, G Jiménez-Osés, GJL Bernardes
Methods Mol Biol
(2019)
2033
(doi: 10.1007/978-1-4939-9654-4_3)
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y-C Liao, M Fernandopulle, G Wang, H Choi, L Hao, CM Drerup, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, M Nelson, M Czekalska, G Musteikyte, R Patel, C Stephens, A Pasolli, L Forrest, P St George-Hyslop, J Lippincott-Schwartz, ME Ward
(2019)
(doi: 10.2139/ssrn.3312723)
Oligomer Diversity during the Aggregation of the Repeat Region of Tau.
M Kjaergaard, AJ Dear, F Kundel, S Qamar, G Meisl, TPJ Knowles, D Klenerman
ACS Chemical Neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00250)
Stabilization and Characterization of Cytotoxic Aβ
B Mannini, J Habchi, S Chia, FS Ruggeri, M Perni, TPJ Knowles, CM Dobson, M Vendruscolo
ACS Chem Neurosci
(2018)
9
(doi: 10.1021/acschemneuro.8b00141)
Resolving protein mixtures using microfluidic diffusional sizing combined with synchrotron radiation circular dichroism
C Bortolini, T Kartanas, D Copic, I Condado Morales, Y Zhang, PK Challa, Q Peter, T Jávorfi, R Hussain, M Dong, G Siligardi, TPJ Knowles, J Charmet
Lab on A Chip
(2018)
19
(doi: 10.1039/c8lc00757h)
Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming
N Ahmed, P Sormanni, P Ciryam, M Vendruscolo, CM Dobson, EP O’Brien
(2018)
(doi: 10.1101/490755)
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology.
H Fu, A Possenti, R Freer, Y Nakano, NC Hernandez Villegas, M Tang, PVM Cauhy, BA Lassus, S Chen, SL Fowler, HY Figueroa, ED Huey, GVW Johnson, M Vendruscolo, KE Duff
Nature neuroscience
(2018)
22
(doi: 10.1038/s41593-018-0298-7)
One-pot stapling of interchain disulfides of antibodies using an isobutylene motif
S Sun, P Akkapeddi, MC Marques, N Martínez-Sáez, VM Torres, C Cordeiro, O Boutureira, GJL Bernardes
Organic & Biomolecular Chemistry
(2018)
17
(doi: 10.1039/c8ob02877j)
Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
Nano Letters
(2018)
18
(doi: 10.1021/acs.nanolett.8b02916)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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