Centre for Misfolding Diseases

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  • Currently displaying 921 - 940 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Enhancing the Resolution of Micro Free Flow Electrophoresis through Spatially Controlled Sample Injection.
KL Saar, T Müller, J Charmet, PK Challa, TPJ Knowles
Analytical chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b01205)
Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid α-synuclein fibrils
FS Ruggeri, F Benedetti, TPJ Knowles, HA Lashuel, S Sekatskii, G Dietler
Proceedings of the National Academy of Sciences
(2018)
115
(doi: 10.1073/pnas.1721220115)
Determination of Polypeptide Conformation with Nanoscale Resolution in Water.
G Ramer, FS Ruggeri, A Levin, TPJ Knowles, A Centrone
ACS nano
(2018)
12
(doi: 10.1021/acsnano.8b01425)
Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers.
DR Whiten, D Cox, MH Horrocks, CG Taylor, S De, P Flagmeier, L Tosatto, JR Kumita, H Ecroyd, CM Dobson, D Klenerman, MR Wilson
Cell Reports
(2018)
23
(doi: 10.1016/j.celrep.2018.05.074)
Origin of metastable oligomers and their effects on amyloid fibril self-assembly
F Hasecke, T Miti, C Perez, J Barton, D Schölzel, L Gremer, CSR Grüning, G Matthews, G Meisl, TPJ Knowles, D Willbold, P Neudecker, H Heise, G Ullah, W Hoyer, M Muschol
Chemical Science
(2018)
9
(doi: 10.1039/c8sc01479e)
On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations.
X Yang, G Meisl, B Frohm, E Thulin, TPJ Knowles, S Linse
Proc Natl Acad Sci U S A
(2018)
115
(doi: 10.1073/pnas.1803539115)
Kinetic Analysis of Amyloid Formation
G Meisl, TCT Michaels, S Linse, TPJ Knowles
Methods in molecular biology (Clifton, N.J.)
(2018)
1779
(doi: 10.1007/978-1-4939-7816-8_12)
Cooperative Assembly of Hsp70 Subdomain Clusters.
MA Wright, FA Aprile, MMJ Bellaiche, TCT Michaels, T Müller, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Biochemistry
(2018)
57
(doi: 10.1021/acs.biochem.8b00151)
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.
Y Song, TCT Michaels, Q Ma, Z Liu, H Yuan, S Takayama, TPJ Knowles, HC Shum
Nature Communications
(2018)
9
(doi: 10.1038/s41467-018-04510-3)
C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH
IM van der Wateren, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion
Chem Sci
(2018)
9
(doi: 10.1039/c8sc01109e)
Reaction rate theory for supramolecular kinetics: application to protein aggregation
TCT Michaels, LX Liu, S Curk, PG Bolhuis, A Šarić, TPJ Knowles
Molecular Physics
(2018)
116
(doi: 10.1080/00268976.2018.1474280)
Stochastic calculus of protein filament formation under spatial confinement
TCT Michaels, AJ Dear, TPJ Knowles
New Journal of Physics
(2018)
20
(doi: 10.1088/1367-2630/aac0bc)
Rapid Growth of Acetylated Aβ(16-20) into Macroscopic Crystals.
C Bortolini, LH Klausen, SV Hoffmann, NC Jones, D Saadeh, Z Wang, TPJ Knowles, M Dong
ACS Nano
(2018)
12
(doi: 10.1021/acsnano.8b00448)
A rationally designed Hsp70 variant rescues the aggregation-associated toxicity of human IAPP in cultured pancreatic islet β-cells
MN Bongiovanni, FA Aprile, P Sormanni, M Vendruscolo
International Journal of Molecular Sciences
(2018)
(doi: 10.3390/ijms19051443)
Developing NMR methods for macromolecular machines: Measurement of residual dipolar couplings to probe dynamic regions of the ribosome
X Wang, JP Kirkpatrick, HMM Launay, A de Simone, D Häussinger, CM Dobson, M Vendruscolo, LD Cabrita, CA Waudby, J Christodoulou
(2018)
(doi: 10.1101/319251)
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes.
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, FS Ruggeri, M Sanguanini, I Idini, JR Kumita, E Sparr, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Nat Chem
(2018)
10
(doi: 10.1038/s41557-018-0031-x)
Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity
T Le Marchand, M de Rosa, N Salvi, BM Sala, LB Andreas, E Barbet-Massin, P Sormanni, A Barbiroli, R Porcari, C Sousa Mota, D de Sanctis, M Bolognesi, L Emsley, V Bellotti, M Blackledge, C Camilloni, G Pintacuda, S Ricagno
Nature communications
(2018)
9
(doi: 10.1038/s41467-018-04078-y)
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
S Qamar, G Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, EC Phillips, A Miyashita, D Williams, F Ströhl, W Meadows, R Ferry, VJ Dardov, GG Tartaglia, LA Farrer, GS Kaminski Schierle, CF Kaminski, CE Holt, PE Fraser, G Schmitt-Ulms, D Klenerman, T Knowles, M Vendruscolo, P St George-Hyslop
Cell
(2018)
173
(doi: 10.1016/j.cell.2018.03.056)
Sustainable Polysulfides for Oil Spill Remediation: Repurposing Industrial Waste for Environmental Benefit
MJH Worthington, CJ Shearer, LJ Esdaile, JA Campbell, CT Gibson, SK Legg, Y Yin, NA Lundquist, JR Gascooke, IS Albuquerque, JG Shapter, GG Andersson, DA Lewis, GJL Bernardes, JM Chalker
Advanced Sustainable Systems
(2018)
2
(doi: 10.1002/adsu.201800024)
Parapred: antibody paratope prediction using convolutional and recurrent neural networks
E Liberis, P Velickovic, P Sormanni, M Vendruscolo, P Liò
Bioinformatics
(2018)
34
(doi: 10.1093/bioinformatics/bty305)
Yusuf Hamied Department of Chemistry
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