Centre for Misfolding Diseases

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  • Currently displaying 921 - 940 of 2393 publications
Author(s)
Publication title
Journal Name
Publication year
Stochastic calculus of protein filament formation under spatial confinement
TCT Michaels, AJ Dear, TPJ Knowles
New Journal of Physics
(2018)
20
(doi: 10.1088/1367-2630/aac0bc)
Rapid Growth of Acetylated Aβ(16-20) into Macroscopic Crystals
C Bortolini, LH Klausen, SV Hoffmann, NC Jones, D Saadeh, Z Wang, TPJ Knowles, M Dong
ACS Nano
(2018)
12
(doi: 10.1021/acsnano.8b00448)
A rationally designed Hsp70 variant rescues the aggregation-associated toxicity of human IAPP in cultured pancreatic islet β-cells
MN Bongiovanni, FA Aprile, P Sormanni, M Vendruscolo
International Journal of Molecular Sciences
(2018)
(doi: 10.3390/ijms19051443)
Developing NMR methods for macromolecular machines: Measurement of residual dipolar couplings to probe dynamic regions of the ribosome
X Wang, JP Kirkpatrick, HMM Launay, A de Simone, D Häussinger, CM Dobson, M Vendruscolo, LD Cabrita, CA Waudby, J Christodoulou
(2018)
(doi: 10.1101/319251)
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, FS Ruggeri, M Sanguanini, I Idini, JR Kumita, E Sparr, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Nature chemistry
(2018)
10
(doi: 10.1038/s41557-018-0031-x)
Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity
T Le Marchand, M de Rosa, N Salvi, BM Sala, LB Andreas, E Barbet-Massin, P Sormanni, A Barbiroli, R Porcari, C Sousa Mota, D de Sanctis, M Bolognesi, L Emsley, V Bellotti, M Blackledge, C Camilloni, G Pintacuda, S Ricagno
Nat Commun
(2018)
9
(doi: 10.1038/s41467-018-04078-y)
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
S Qamar, G Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, EC Phillips, A Miyashita, D Williams, F Ströhl, W Meadows, R Ferry, VJ Dardov, GG Tartaglia, LA Farrer, GS Kaminski Schierle, CF Kaminski, CE Holt, PE Fraser, G Schmitt-Ulms, D Klenerman, T Knowles, M Vendruscolo, P St George-Hyslop
Cell
(2018)
173
(doi: 10.1016/j.cell.2018.03.056)
Sustainable Polysulfides for Oil Spill Remediation: Repurposing Industrial Waste for Environmental Benefit
MJH Worthington, CJ Shearer, LJ Esdaile, JA Campbell, CT Gibson, SK Legg, Y Yin, NA Lundquist, JR Gascooke, IS Albuquerque, JG Shapter, GG Andersson, DA Lewis, GJL Bernardes, JM Chalker
Advanced Sustainable Systems
(2018)
2
(doi: 10.1002/adsu.201800024)
Parapred: Antibody paratope prediction using convolutional and recurrent neural networks
E Liberis, P Velickovic, P Sormanni, M Vendruscolo, P Liò
Bioinformatics
(2018)
34
(doi: 10.1093/bioinformatics/bty305)
Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy
M Bonomi, R Pellarin, M Vendruscolo
Biophysical Journal
(2018)
114
(doi: 10.1016/j.bpj.2018.02.028)
Water-Dispersible Polydopamine-Coated Nanofibers for Stimulation of Neuronal Growth and Adhesion
S Sieste, T Mack, CV Synatschke, C Schilling, C Meyer Zu Reckendorf, L Pendi, S Harvey, FS Ruggeri, TPJ Knowles, C Meier, DYW Ng, T Weil, B Knöll
Advanced Healthcare Materials
(2018)
7
(doi: 10.1002/adhm.201701485)
Biophotonics of Native Silk Fibrils
U Shimanovich, D Pinotsi, K Shimanovich, N Yu, S Bolisetty, J Adamcik, R Mezzenga, J Charmet, F Vollrath, E Gazit, CM Dobson, GK Schierle, C Holland, CF Kaminski, TPJ Knowles
Macromolecular Bioscience
(2018)
18
(doi: 10.1002/mabi.201700295)
Molecular determinants of the interaction of EGCG with ordered and disordered proteins.
G Fusco, M Sanz-Hernandez, FS Ruggeri, M Vendruscolo, CM Dobson, A De Simone
Biopolymers
(2018)
109
(doi: 10.1002/bip.23117)
Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading.
F Kundel, L Hong, B Falcon, WA McEwan, TCT Michaels, G Meisl, N Esteras, AY Abramov, TJP Knowles, M Goedert, D Klenerman
ACS Chem Neurosci
(2018)
9
(doi: 10.1021/acschemneuro.8b00094)
Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species (vol 5, 171399, 2018)
L-M Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, M Rodrigues, CM Dobson, S Gandhi, SE Bohndiek, TN Snaddon, SF Lee
Royal Society Open Science
(2018)
5
(doi: 10.1098/rsos.180308)
Artificial Intelligence Recognizes β-Lapachone as an Allosteric 5- Lipoxygenase Inhibitor
G Bernardes, T Rodrigues, M Werner, J Roth, EHG da Cruz, MC Marques, SA Lobo, A Koeberle, F Corzana, E N. da Silva Júnior, O Werz
(2018)
(doi: 10.26434/chemrxiv.6026795.v1)
Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide.
SIA Cohen, R Cukalevski, TCT Michaels, A Šarić, M Törnquist, M Vendruscolo, CM Dobson, AK Buell, TPJ Knowles, S Linse
Nature Chemistry
(2018)
10
(doi: 10.1038/s41557-018-0023-x)
The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity
D Cox, DR Whiten, JWP Brown, MH Horrocks, R San Gil, CM Dobson, D Klenerman, AM van Oijen, H Ecroyd
J Biol Chem
(2018)
293
(doi: 10.1074/jbc.M117.813865)
Optical Structural Analysis of Individual α‐Synuclein Oligomers
JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, D Klenerman, SF Lee
Angewandte Chemie
(2018)
130
(doi: 10.1002/ange.201710779)
Chemo- and Regioselective Lysine Modification on Native Proteins
MJ Matos, BL Oliveira, N Martínez-Sáez, A Guerreiro, PMSD Cal, J Bertoldo, M Maneiro, E Perkins, J Howard, MJ Deery, JM Chalker, F Corzana, G Jiménez-Osés, GJL Bernardes
J Am Chem Soc
(2018)
140
(doi: 10.1021/jacs.7b12874)
Yusuf Hamied Department of Chemistry
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