Centre for Misfolding Diseases

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  • Currently displaying 901 - 920 of 2401 publications
Author(s)
Publication title
Journal Name
Publication year
DNA-Coated Functional Oil Droplets.
A Caciagli, M Zupkauskas, A Levin, TPJ Knowles, C Mugemana, N Bruns, T O'Neill, WJ Frith, E Eiser
Langmuir
(2018)
34
(doi: 10.1021/acs.langmuir.8b01828)
Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates.
MJ Matos, C Labão-Almeida, C Sayers, O Dada, M Tacke, GJL Bernardes
Chemistry A European Journal
(2018)
24
(doi: 10.1002/chem.201800872)
Self-Assembly-Mediated Release of Peptide Nanoparticles through Jets Across Microdroplet Interfaces.
A Levin, TCT Michaels, TO Mason, T Müller, L Adler-Abramovich, L Mahadevan, ME Cates, E Gazit, TPJ Knowles
ACS Applied Materials & Interfaces
(2018)
10
(doi: 10.1021/acsami.8b09511)
Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson's disease model.
D Chatterjee, M Bhatt, D Butler, E De Genst, CM Dobson, A Messer, JH Kordower
NPJ Parkinsons Dis
(2018)
4
(doi: 10.1038/s41531-018-0062-4)
Obituary: Nico van Nuland 1961-2017.
A Matagne, CM Dobson
Eur Biophys J
(2018)
47
(doi: 10.1007/s00249-018-1326-y)
A structural ensemble modulation mechanism of small molecule binding to disordered proteins
GT Heller, M Bonomi, M Vendruscolo
J Mol Biol
(2018)
430
(doi: 10.1016/j.jmb.2018.03.015)
The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation (vol 7, 9039, 2017)
FA Aprile, E Källstig, G Limorenko, M Vendruscolo, D Ron, C Hansen
Sci Rep
(2018)
8
(doi: 10.1038/s41598-018-29893-7)
Combining Affinity Selection and Specific Ion Mobility for Microchip Protein Sensing
WE Arter, J Charmet, J Kong, KL Saar, TW Herling, T Müller, UF Keyser, TPJ Knowles
Analytical chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b02051)
Massively parallel C elegans tracking provides multi-dimensional fingerprints for phenotypic discovery
M Perni, PK Challa, JB Kirkegaard, R Limbocker, M Koopman, MC Hardenberg, P Sormanni, T Müller, KL Saar, LWY Roode, J Habchi, G Vecchi, N Fernando, S Casford, EAA Nollen, M Vendruscolo, CM Dobson, TPJ Knowles
J Neurosci Methods
(2018)
306
(doi: 10.1016/j.jneumeth.2018.02.005)
Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation
C Månsson, RTP van Cruchten, U Weininger, X Yang, R Cukalevski, P Arosio, CM Dobson, T Knowles, M Akke, S Linse, C Emanuelsson
Biochemistry
(2018)
57
(doi: 10.1021/acs.biochem.8b00353)
Structural differences between toxic and nontoxic HypF-N oligomers
C Capitini, JR Patel, A Natalello, C D'Andrea, A Relini, JA Jarvis, L Birolo, A Peduzzo, M Vendruscolo, P Matteini, CM Dobson, A De Simone, F Chiti
Chem Commun (Camb)
(2018)
54
(doi: 10.1039/c8cc03446j)
Machine intelligence decrypts -lapachone as an allosteric 5-lipoxygenase inhibitor
T Rodrigues, M Werner, J Roth, EHG da Cruz, MC Marques, P Akkapeddi, SA Lobo, A Koeberle, F Corzana, EN da Silva Júnior, O Werz, GJL Bernardes
Chemical science
(2018)
9
(doi: 10.1039/c8sc02634c)
Site-selective installation of an electrophilic handle on proteins for bioconjugation
B Lee, S Sun, E Jiménez-Moreno, AA Neves, GJL Bernardes
Bioorganic and Medicinal Chemistry
(2018)
26
(doi: 10.1016/j.bmc.2018.02.028)
Molecular dynamics ensemble refinement of the heterogeneous native state of NCBD using chemical shifts and NOEs.
E Papaleo, C Camilloni, K Teilum, M Vendruscolo, K Lindorff-Larsen
PeerJ
(2018)
2018
(doi: 10.7717/peerj.5125)
O2‐02‐02: TARGETING AMYLOID FORMATION USING RATIONALLY DESIGNED ANTIBODIES
FA Aprile, P Sormanni, M Perni, P Arosio, R Limbocker, S Chhangur, B Mannini, S Linse, T Knowles, CM Dobson, M Vendruscolo
Alzheimer's & Dementia
(2018)
14
(doi: 10.1016/j.jalz.2018.06.2646)
Exploring the role of post-translational modifications in regulating α-synuclein interactions by studying the effects of phosphorylation on nanobody binding
F El Turk, E De Genst, T Guilliams, B Fauvet, M Hejjaoui, J Di Trani, A Chiki, A Mittermaier, M Vendruscolo, HA Lashuel, CM Dobson
Protein Sci
(2018)
27
(doi: 10.1002/pro.3412)
O3‐01‐05: IN VITRO MEASUREMENTS OF TAU AGGREGATE ELONGATION AND FRAGMENTATION RATES ALLOW THE MODELLING OF PRION‐LIKE SPREADING IN HUMANS
D Klenerman, F Kundel, B Falcon, T Knowles, M Goedert, L Hong, W McEwan, G Meisl
Alzheimer's & Dementia
(2018)
14
(doi: 10.1016/j.jalz.2018.06.2774)
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.
M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, GT Heller, G Meisl, SW Chen, JR Kumita, PK Challa, JB Kirkegaard, SIA Cohen, B Mannini, D Barbut, EAA Nollen, C Cecchi, N Cremades, TPJ Knowles, F Chiti, M Zasloff, M Vendruscolo, CM Dobson
ACS Chemical Biology
(2018)
13
(doi: 10.1021/acschembio.8b00466)
Enhancing the Resolution of Micro Free Flow Electrophoresis through Spatially Controlled Sample Injection
KL Saar, T Müller, J Charmet, PK Challa, TPJ Knowles
Anal Chem
(2018)
90
(doi: 10.1021/acs.analchem.8b01205)
Reversible inhibition of the ClpP protease via an N-terminal conformational switch.
S Vahidi, ZA Ripstein, M Bonomi, T Yuwen, MF Mabanglo, JB Juravsky, K Rizzolo, A Velyvis, WA Houry, M Vendruscolo, JL Rubinstein, LE Kay
Proc Natl Acad Sci U S A
(2018)
115
(doi: 10.1073/pnas.1805125115)
Yusuf Hamied Department of Chemistry
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