Centre for Misfolding Diseases

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  • Currently displaying 901 - 920 of 2336 publications
Author(s)
Publication title
Journal Name
Publication year
The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis.
MA Hanspal, CM Dobson, JJ Yerbury, JR Kumita
Biochim Biophys Acta Mol Basis Dis
(2017)
1863
(doi: 10.1016/j.bbadis.2017.07.007)
The contribution of biophysical and structural studies of protein self-assembly to the design of therapeutic strategies for amyloid diseases.
N Cremades, CM Dobson
Neurobiol Dis
(2017)
109
(doi: 10.1016/j.nbd.2017.07.009)
Protein homeostasis of a metastable subproteome associated with Alzheimer's disease
R Kundra, P Ciryam, RI Morimoto, CM Dobson, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2017)
114
(doi: 10.1073/pnas.1618417114)
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species
D Klenerman, M Iljina, L Hong, MH Horrocks, MH Ludtmann, ML Choi, CD Hughes, FS Ruggeri, T Guilliams, AK Buell, J-E Lee, S Gandhi, SF Lee, CE Bryant, M Vendruscolo, TPJ Knowles, CM Dobson, E De Genst, D Klenerman
BMC Biol
(2017)
15
(doi: 10.1186/s12915-017-0390-6)
Inverse electron demand Diels-Alder reactions in chemical biology
GJ Lopes Bernardes, BL Oliveira, Z Guo
Chemical Society Reviews
(2017)
46
(doi: 10.1039/c7cs00184c)
Amyloid-like Fibrils from an α‑Helical Transmembrane Protein
K Stroobants, JR Kumita, NJ Harris, DY Chirgadze, CM Dobson, PJ Booth, M Vendruscolo
Biochemistry
(2017)
56
(doi: 10.1021/acs.biochem.7b00157)
Ultrasensitive Measurement of Ca<sup>2+</sup> Influx into Lipid Vesicles Induced by Protein Aggregates.
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TPJ Knowles, S Gandhi, CM Dobson, D Klenerman
Angewandte Chemie - International Edition
(2017)
56
(doi: 10.1002/anie.201700966)
Protein homeostasis of a metastable subproteome associated with Alzheimer’s disease
R Kundra, P Ciryam, RI Morimoto, CM Dobson, M Vendruscolo
Proceedings of the National Academy of Sciences
(2017)
114
(doi: 10.1073/pnas.1618417114)
Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method.
FA Aprile, P Sormanni, M Perni, P Arosio, S Linse, TPJ Knowles, CM Dobson, M Vendruscolo
Science advances
(2017)
3
(doi: 10.1126/sciadv.1700488)
Direct Conversion of an Enzyme from Native-like to Amyloid-like Aggregates within Inclusion Bodies.
F Elia, F Cantini, F Chiti, CM Dobson, F Bemporad
Biophysical journal
(2017)
112
(doi: 10.1016/j.bpj.2017.05.011)
Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication.
A Munke, J Persson, T Weiffert, E De Genst, G Meisl, P Arosio, A Carnerup, CM Dobson, M Vendruscolo, TPJ Knowles, S Linse
Proc Natl Acad Sci U S A
(2017)
114
(doi: 10.1073/pnas.1700407114)
Self‐assembled Protein Fibril‐metal Oxide Nanocomposites
A Levin, TO Mason, TPJ Knowles, U Shimanovich
Israel Journal of Chemistry
(2017)
57
(doi: 10.1002/ijch.201600118)
Corrigendum: A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages.
MMA Pereira, I Mahú, E Seixas, N Martinéz-Sánchez, N Kubasova, RM Pirzgalska, P Cohen, MO Dietrich, M López, GJL Bernardes, AI Domingos
Nat Commun
(2017)
8
(doi: 10.1038/ncomms15673)
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
F Chiti, CM Dobson
Annual review of biochemistry
(2017)
86
(doi: 10.1146/annurev-biochem-061516-045115)
Frontispiece: Site‐Selective Modification of Proteins with Oxetanes
O Boutureira, N Martínez‐Sáez, KM Brindle, AA Neves, F Corzana, GJL Bernardes
Chemistry - A European Journal
(2017)
23
(doi: 10.1002/chem.201782762)
Corrigendum: Structural basis of synaptic vesicle assembly promoted by α-synuclein.
G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, GSK Schierle, M Vendruscolo, G Veglia, CM Dobson, A De Simone
Nature communications
(2017)
8
(doi: 10.1038/ncomms15667)
Structural Characterization of the Early Events in the Nucleation-Condensation Mechanism in a Protein Folding Process
P Kukic, Y Pustovalova, C Camilloni, S Gianni, DM Korzhnev, M Vendruscolo
Journal of the American Chemical Society
(2017)
139
(doi: 10.1021/jacs.7b01540)
Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TPJ Knowles, S Gandhi, CM Dobson, D Klenerman
Angewandte Chemie
(2017)
129
(doi: 10.1002/ange.201700966)
Protein modification
TT-L Kwan, O Boutureira, EC Frye, SJ Walsh, MK Gupta, S Wallace, Y Wu, F Zhang, HF Sore, WRJD Galloway, JW Chin, M Welch, GJL Bernardes, DR Spring
Chemical science
(2017)
8
(doi: 10.1039/c6sc05313k)
Site‐Selective Modification of Proteins with Oxetanes
O Boutureira, N Martínez-Sáez, KM Brindle, AA Neves, F Corzana, GJ Lopes Bernardes
Chemistry A European Journal
(2017)
23
(doi: 10.1002/chem.201700745)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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