Centre for Misfolding Diseases

Publications

Tips on using this search form

  • All search terms are case-insensitive
  • If you specify more than one search option (e.g. you search for both "Authors" and "Paper title") then the publications returned will be those that match all of your search terms
  • To reset the search form, click here
  • Currently displaying 881 - 900 of 2401 publications
Author(s)
Publication title
Journal Name
Publication year
Cisplatin-Triggered Bioorthogonal Decaging of Amide Bonds for Targeted-Drug Activation in vivo
B Stenton, B Oliveira, J Conde, M Negrão, M Godinho Ferreira, R Fior, G Bernardes
(2018)
(doi: 10.26434/chemrxiv.7327904.v1)
Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools.
L Shan, N Mody, P Sormani, KL Rosenthal, MM Damschroder, R Esfandiary
Mol Pharm
(2018)
15
(doi: 10.1021/acs.molpharmaceut.8b00867)
Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling
M Bonomi, S Hanot, CH Greenberg, A Sali, M Nilges, M Vendruscolo, R Pellarin
Structure
(2018)
27
(doi: 10.1016/j.str.2018.09.011)
Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform.
M Perni, S Casford, FA Aprile, EA Nollen, TPJ Knowles, M Vendruscolo, CM Dobson
Journal of visualized experiments : JoVE
(2018)
2018
(doi: 10.3791/58643)
Posttranslational chemical mutagenesis: to reveal the role of non-catalytic cysteine residues in pathogenic bacterial phosphatases
JB Bertoldo, H Terenzi, S Hüttelmaier, GJL Bernardes
Biochemistry
(2018)
57
(doi: 10.1021/acs.biochem.8b00639)
Statistical Mechanics of Globular Oligomer Formation by Protein Molecules.
AJ Dear, A Šarić, TCT Michaels, CM Dobson, TPJ Knowles
J Phys Chem B
(2018)
122
(doi: 10.1021/acs.jpcb.8b07805)
Direct Observation of Murine Prion Protein Replication in Vitro.
JC Sang, G Meisl, AM Thackray, L Hong, A Ponjavic, TPJ Knowles, R Bujdoso, D Klenerman
Journal of the American Chemical Society
(2018)
140
(doi: 10.1021/jacs.8b08311)
¬Nanoscopic characterization of individual endogenous protein aggregates in human neuronal cells
DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M-G Spillantini, D Klenerman, MH Horrocks
ChemBioChem
(2018)
19
(doi: 10.1002/cbic.201800209)
A bioinformatics approach to define the aggregation capacity of the myofiber proteome in inclusion body myositis
C Weihl, P Ciryam, A Guttsches, K Marcus, R Morimoto, M Vendruscolo, R Kley
Neuromuscular Disorders
(2018)
28
(doi: 10.1016/j.nmd.2018.06.188)
SAR by kinetics for drug discovery in protein misfolding diseases.
S Chia, J Habchi, TCT Michaels, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2018)
115
(doi: 10.1073/pnas.1807884115)
Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity
FS Ruggeri, J Charmet, T Kartanas, Q Peter, S Chia, J Habchi, CM Dobson, M Vendruscolo, TPJ Knowles
Nature communications
(2018)
9
(doi: 10.1038/s41467-018-06345-4)
Solution Fibre Spinning Technique for the Fabrication of Tuneable Decellularised Matrix-Laden Fibres and Fibrous Micromembranes
Z Li, J Tuffin, IM Lei, FS Ruggeri, NS Lewis, EL Gill, T Savin, L Huleihel, SF Badylak, T Knowles, SC Satchell, GI Welsh, MA Saleem, YYS Huang
Acta Biomater
(2018)
78
(doi: 10.1016/j.actbio.2018.08.010)
Determination of the conformational states of strychnine in solution using NMR residual dipolar couplings in a tensor-free approach.
G Tomba, C Camilloni, M Vendruscolo
Methods
(2018)
148
(doi: 10.1016/j.ymeth.2018.07.005)
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in C. elegans
C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, T Sinnige, MC Lechler, N Schlörit, RF Laine, CH Michel, M Vendruscolo, CF Kaminski, GSK Schierle, DC David
(2018)
(doi: 10.1101/417873)
Fast fluorescence lifetime imaging reveals the aggregation processes of α-synuclein and polyglutamine in aging Caenorhabditis elegans
RF Laine, T Sinnige, K Yu, AJ Haack, C Poudel, P Gaida, N Curry, M Perni, EAA Nollen, CM Dobson, M Vendruscolo, GSK Schierle, CF Kaminski
(2018)
(doi: 10.1101/414714)
Systematic mapping of free energy landscapes of a growing filamin domain during biosynthesis.
CA Waudby, T Wlodarski, M-E Karyadi, AME Cassaignau, SHS Chan, AS Wentink, JM Schmidt-Engler, C Camilloni, M Vendruscolo, LD Cabrita, J Christodoulou
Proceedings of the National Academy of Sciences
(2018)
115
(doi: 10.1073/pnas.1716252115)
Extrinsic Amyloid-Binding Dyes for the Detection of Individual Protein Aggregates in Solution
D Klenerman
Analytical Chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b02226)
A method for partitioning the information contained in a protein sequence between its structure and function.
A Possenti, M Vendruscolo, C Camilloni, G Tiana
Proteins: Structure, Function, and Bioinformatics
(2018)
86
(doi: 10.1002/prot.25527)
Discovery of 2,4-dimethoxypyridines as novel autophagy inhibitors
L Robke, T Rodrigues, P Schröder, DJ Foley, GJL Bernardes, L Laraia, H Waldmann
Tetrahedron
(2018)
74
(doi: 10.1016/j.tet.2018.07.021)
Identification of Oxidative Stress in Red Blood Cells with Nanoscale Chemical Resolution by Infrared Nanospectroscopy
FS Ruggeri, C Marcott, S Dinarelli, G Longo, M Girasole, G Dietler, TPJ Knowles
International Journal of Molecular Sciences
(2018)
19
(doi: 10.3390/ijms19092582)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
Contacts
Directions

Privacy and cookie policy

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge