Centre for Misfolding Diseases

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  • Currently displaying 881 - 900 of 2396 publications
Author(s)
Publication title
Journal Name
Publication year
Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling.
M Bonomi, S Hanot, CH Greenberg, A Sali, M Nilges, M Vendruscolo, R Pellarin
Structure (London, England : 1993)
(2018)
27
(doi: 10.1016/j.str.2018.09.011)
Posttranslational Chemical Mutagenesis: To Reveal the Role of Noncatalytic Cysteine Residues in Pathogenic Bacterial Phosphatases.
JB Bertoldo, H Terenzi, S Hüttelmaier, GJL Bernardes
Biochemistry
(2018)
57
(doi: 10.1021/acs.biochem.8b00639)
Statistical Mechanics of Globular Oligomer Formation by Protein Molecules
AJ Dear, A Šarić, TCT Michaels, CM Dobson, TPJ Knowles
Journal of Physical Chemistry B
(2018)
122
(doi: 10.1021/acs.jpcb.8b07805)
Direct Observation of Murine Prion Protein Replication in Vitro
JC Sang, G Meisl, AM Thackray, L Hong, A Ponjavic, TPJ Knowles, R Bujdoso, D Klenerman
J Am Chem Soc
(2018)
140
(doi: 10.1021/jacs.8b08311)
Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells
DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M-G Spillantini, D Klenerman, MH Horrocks
Chembiochem : a European journal of chemical biology
(2018)
19
(doi: 10.1002/cbic.201800209)
A bioinformatics approach to define the aggregation capacity of the myofiber proteome in inclusion body myositis
C Weihl, P Ciryam, A Guttsches, K Marcus, R Morimoto, M Vendruscolo, R Kley
Neuromuscular Disorders
(2018)
28
(doi: 10.1016/j.nmd.2018.06.188)
SAR by kinetics for drug discovery in protein misfolding diseases
S Chia, J Habchi, TCT Michaels, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proc Natl Acad Sci U S A
(2018)
115
(doi: 10.1073/pnas.1807884115)
Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity
FS Ruggeri, J Charmet, T Kartanas, Q Peter, S Chia, J Habchi, CM Dobson, M Vendruscolo, TPJ Knowles
Nature Communications
(2018)
9
(doi: 10.1038/s41467-018-06345-4)
Solution fibre spinning technique for the fabrication of tuneable decellularised matrix-laden fibres and fibrous micromembranes
Z Li, J Tuffin, IM Lei, FS Ruggeri, NS Lewis, EL Gill, T Savin, L Huleihel, SF Badylak, T Knowles, SC Satchell, GI Welsh, MA Saleem, YYS Huang
Acta biomaterialia
(2018)
78
(doi: 10.1016/j.actbio.2018.08.010)
Determination of the conformational states of strychnine in solution using NMR residual dipolar couplings in a tensor-free approach
G Tomba, C Camilloni, M Vendruscolo
Methods (San Diego, Calif.)
(2018)
148
(doi: 10.1016/j.ymeth.2018.07.005)
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in C. elegans
C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, T Sinnige, MC Lechler, N Schlörit, RF Laine, CH Michel, M Vendruscolo, CF Kaminski, GSK Schierle, DC David
(2018)
(doi: 10.1101/417873)
Fast fluorescence lifetime imaging reveals the aggregation processes of α-synuclein and polyglutamine in aging Caenorhabditis elegans
RF Laine, T Sinnige, K Yu, AJ Haack, C Poudel, P Gaida, N Curry, M Perni, EAA Nollen, CM Dobson, M Vendruscolo, GSK Schierle, CF Kaminski
(2018)
(doi: 10.1101/414714)
Systematic mapping of free energy landscapes of a growing filamin domain during biosynthesis
CA Waudby, T Wlodarski, M-E Karyadi, AME Cassaignau, SHS Chan, AS Wentink, JM Schmidt-Engler, C Camilloni, M Vendruscolo, LD Cabrita, J Christodoulou
Proc Natl Acad Sci U S A
(2018)
115
(doi: 10.1073/pnas.1716252115)
Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution
D Klenerman
Anal Chem
(2018)
90
(doi: 10.1021/acs.analchem.8b02226)
A method for partitioning the information contained in a protein sequence between its structure and function
A Possenti, M Vendruscolo, C Camilloni, G Tiana
Proteins
(2018)
86
(doi: 10.1002/prot.25527)
Identification of Oxidative Stress in Red Blood Cells with Nanoscale Chemical Resolution by Infrared Nanospectroscopy.
FS Ruggeri, C Marcott, S Dinarelli, G Longo, M Girasole, G Dietler, TPJ Knowles
Int J Mol Sci
(2018)
19
(doi: 10.3390/ijms19092582)
Discovery of 2,4-dimethoxypyridines as novel autophagy inhibitors
L Robke, T Rodrigues, P Schröder, DJ Foley, GJL Bernardes, L Laraia, H Waldmann
Tetrahedron
(2018)
74
(doi: 10.1016/j.tet.2018.07.021)
DNA-Coated Functional Oil Droplets.
A Caciagli, M Zupkauskas, A Levin, TPJ Knowles, C Mugemana, N Bruns, T O'Neill, WJ Frith, E Eiser
Langmuir
(2018)
34
(doi: 10.1021/acs.langmuir.8b01828)
Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson's disease model.
D Chatterjee, M Bhatt, D Butler, E De Genst, CM Dobson, A Messer, JH Kordower
NPJ Parkinsons Dis
(2018)
4
(doi: 10.1038/s41531-018-0062-4)
Synthesis and Biological Evaluation of Homogeneous Thiol‐Linked NHC*‐Au‐Albumin and ‐Trastuzumab Bioconjugates
MJ Matos, C Labão-Almeida, C Sayers, O Dada, M Tacke, GJL Bernardes
Chemistry (Weinheim an der Bergstrasse, Germany)
(2018)
24
(doi: 10.1002/chem.201800872)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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