Centre for Misfolding Diseases

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  • Currently displaying 861 - 880 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming
N Ahmed, P Sormanni, P Ciryam, M Vendruscolo, CM Dobson, EP O’Brien
(2018)
(doi: 10.1101/490755)
Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
Nano letters
(2018)
18
(doi: 10.1021/acs.nanolett.8b02916)
One-pot stapling of interchain disulfides of antibodies using an isobutylene motif
S Sun, P Akkapeddi, MC Marques, N Martínez-Sáez, VM Torres, C Cordeiro, O Boutureira, GJL Bernardes
Organic & biomolecular chemistry
(2018)
17
(doi: 10.1039/c8ob02877j)
Protein engineering through chemical, genetic and computational manipulation.
I Hamachi, GJL Bernardes
Chemical Society reviews
(2018)
47
(doi: 10.1039/c8cs90125b)
Image-Assisted Microvessel-on-a-Chip Platform for Studying Cancer Cell Transendothelial Migration Dynamics.
C Bertulli, M Gerigk, N Piano, Y Liu, D Zhang, T Müller, TJ Knowles, YYS Huang
Scientific reports
(2018)
8
(doi: 10.1038/s41598-018-30776-0)
Attentive Cross-Modal Paratope Prediction.
A Deac, P VeliČković, P Sormanni
J Comput Biol
(2018)
26
(doi: 10.1089/cmb.2018.0175)
Bioorthogonal Decaging Reactions for Targeted Drug Activation
S Davies, BJ Stenton, GJL Bernardes
Chimia
(2018)
72
(doi: 10.2533/chimia.2018.771)
Mechanobiology of Protein Droplets: Force Arises from Disorder.
TJ Welsh, Y Shen, A Levin, TPJ Knowles
Cell
(2018)
175
(doi: 10.1016/j.cell.2018.11.020)
Quantifying Co-Oligomer Formation by α-Synuclein
M Iljina, AJ Dear, GA Garcia, S De, L Tosatto, P Flagmeier, DR Whiten, TCT Michaels, D Frenkel, CM Dobson, TPJ Knowles, D Klenerman
ACS nano
(2018)
12
(doi: 10.1021/acsnano.8b03575)
Radical-Mediated Thiol-Ene Strategy: Photoactivation of Thiol-Containing Drugs in Cancer Cells.
GJ Lopes Bernardes
Angewandte Chemie International Edition
(2018)
130
(doi: 10.1002/ange.201811338)
Modular Pore-Forming Immunotoxins with Caged Cytotoxicity Tailored by Directed Evolution.
NL Mutter, M Soskine, G Huang, IS Albuquerque, GJL Bernardes, G Maglia
ACS chemical biology
(2018)
13
(doi: 10.1021/acschembio.8b00720)
Determination of Structural Ensembles of Proteins: Restraining vs Reweighting.
R Rangan, M Bonomi, GT Heller, A Cesari, G Bussi, M Vendruscolo
J Chem Theory Comput
(2018)
14
(doi: 10.1021/acs.jctc.8b00738)
Cisplatin-Triggered Bioorthogonal Decaging of Amide Bonds for Targeted-Drug Activation in vivo
B Stenton, B Oliveira, J Conde, M Negrão, M Godinho Ferreira, R Fior, G Bernardes
(2018)
(doi: 10.26434/chemrxiv.7327904.v1)
Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools.
L Shan, N Mody, P Sormani, KL Rosenthal, MM Damschroder, R Esfandiary
Molecular pharmaceutics
(2018)
15
(doi: 10.1021/acs.molpharmaceut.8b00867)
Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling.
M Bonomi, S Hanot, CH Greenberg, A Sali, M Nilges, M Vendruscolo, R Pellarin
Structure
(2018)
27
(doi: 10.1016/j.str.2018.09.011)
Automated Behavioral Analysis of Large C. Elegans Populations Using a Wide Field-of-view Tracking Platform
M Perni, S Casford, FA Aprile, EA Nollen, TPJ Knowles, M Vendruscolo, CM Dobson
J Vis Exp
(2018)
2018
(doi: 10.3791/58643)
Posttranslational Chemical Mutagenesis: To Reveal the Role of Noncatalytic Cysteine Residues in Pathogenic Bacterial Phosphatases.
JB Bertoldo, H Terenzi, S Hüttelmaier, GJL Bernardes
Biochemistry
(2018)
57
(doi: 10.1021/acs.biochem.8b00639)
Statistical Mechanics of Globular Oligomer Formation by Protein Molecules
AJ Dear, A Šarić, TCT Michaels, CM Dobson, TPJ Knowles
The journal of physical chemistry. B
(2018)
122
(doi: 10.1021/acs.jpcb.8b07805)
Direct Observation of Murine Prion Protein Replication in Vitro
JC Sang, G Meisl, AM Thackray, L Hong, A Ponjavic, TPJ Knowles, R Bujdoso, D Klenerman
J Am Chem Soc
(2018)
140
(doi: 10.1021/jacs.8b08311)
Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells
DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M-G Spillantini, D Klenerman, MH Horrocks
ChemBioChem
(2018)
19
(doi: 10.1002/cbic.201800209)
Yusuf Hamied Department of Chemistry
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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