Centre for Misfolding Diseases

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  • Currently displaying 841 - 860 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation.
M Ahn, BI Lee, S Chia, J Habchi, JR Kumita, M Vendruscolo, CM Dobson, CB Park
Chem Commun (Camb)
(2019)
55
(doi: 10.1039/c8cc09288e)
De novo design of potent and selective mimics of IL-2/IL-15
D-A Silva, S Yu, UY Ulge, JB Spangler, KM Jude, C Labão-Almeida, LR Ali, A Quijano-Rubio, M Ruterbusch, I Leung, T Biary, SJ Crowley, E Marcos, CD Walkey, BD Weitzner, F Pardo-Avila, J Castellanos, L Carter, L Stewart, SR Riddell, M Pepper, GJL Bernardes, M Dougan, KC Garcia, D Baker
Nature
(2019)
565
(doi: 10.1038/s41586-018-0830-7)
Effects of α-tubulin acetylation on microtubule structure and stability
L Eshun-Wilson, R Zhang, D Portran, M Nachury, D Toso, T Lohr, M Vendruscolo, M Bonomi, JS Fraser, E Nogales
(2019)
(doi: 10.1101/516591)
Physical determinants of amyloid assembly in biofilm formation
M Andreasen, G Meisl, JD Taylor, TCT Michaels, A Levin, DE Otzen, MR Chapman, CM Dobson, SJ Matthews, TPJ Knowles
Mbio
(2019)
10
(doi: 10.1128/mbio.02279-18)
Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent
MJ Matos, G Jiménez-Osés, GJL Bernardes
Methods Mol Biol
(2019)
2033
(doi: 10.1007/978-1-4939-9654-4_3)
General sol to gel transition of liquid-liqud phase separated protein under shear
Y Shen, S Qamar, D Vigolo, A Kamada, S Zhang, P St George-Hyslop, T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2019)
48
Analysis of αB-crystallin polydispersity in solution through native microfluidic electrophoresis
MA Wright, FS Ruggeri, KL Saar, PK Challa, JLP Benesch, TPJ Knowles
Analyst
(2019)
144
(doi: 10.1039/C9AN00382G)
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y-C Liao, M Fernandopulle, G Wang, H Choi, L Hao, CM Drerup, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, M Nelson, M Czekalska, G Musteikyte, R Patel, C Stephens, A Pasolli, L Forrest, P St George-Hyslop, J Lippincott-Schwartz, ME Ward
(2019)
(doi: 10.2139/ssrn.3312723)
Proteome-wide analysis of protein stability in E. coli using pulse proteolysis
L Zhao, G Vecchi, M Vendruscolo, R Koerner, M Hayer-Hartl, U Hartl
MOLECULAR & CELLULAR PROTEOMICS
(2019)
18
General sol to gel transition of liquid-liqud phase separated protein under shear
Y Shen, S Qamar, D Vigolo, A Kamada, S Zhang, P St George-Hyslop, T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2019)
48
Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation
JM Kirkpatrick, EK Sacramento, M Mazzetto, S Di Sanzo, C Caterino, A Bartolome, M Sanguanini, N Papaevgeniou, M Lefaki, D Childs, E Terzibasi-Tozzini, N Romanov, M Baumgart, W Huber, N Chondrogianni, M Vendruscolo, A Cellerino, A Ori
MOLECULAR & CELLULAR PROTEOMICS
(2019)
18
Nanostructured protein capsules
T Knowles
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
258
The presence of autoantibodies against the prion protein is independent of PRNP mutations
K Frontzek, M Carta, M Losa, M Epskamp, G Meisl, U Camenisch, T Knowles, S Hornemann, A Aguzzi
PRION
(2019)
13
Efficient and irreversible antibody-cysteine bioconjugation using carbonylacrylic reagents
B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ACB Burtoloso, G Jiménez-Osés, F Corzana, GJL Bernardes
Nature Protocols
(2019)
14
(doi: 10.1038/s41596-018-0083-9)
Cytosolic aggregation of mitochondrial precursor proteins stimulates degeneration of cellular homeostasis
U Nowicka, P Chroscicki, K Stroobants, M Sladowska, M Turek, B Uszczynska-Ratajczak, R Kundra, T Goral, M Vendruscolo, A Chacinska
FEBS OPEN BIO
(2019)
9
Endogenous metabolites rescue a C. elegans model of Alzheimer's disease by triggering a heat shock response
P Joshi, M Perni, R Limbocker, B Mannini, S Casford, S Chia, J Labbadia, C Dobson, M Vendruscolo
FEBS OPEN BIO
(2019)
9
Oligomer diversity during the aggregation of the repeat-region of tau
M Kjaergaard, AJ Dear, F Kundel, S Qamar, G Meisl, TPJ Knowles, D Klenerman
ACS chemical neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00250)
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions
B Mannini, J Habchi, S Chia, FS Ruggeri, M Perni, TPJ Knowles, CM Dobson, M Vendruscolo
ACS chemical neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00141)
Resolving protein mixtures using microfluidic diffusional sizing combined with synchrotron radiation circular dichroism
C Bortolini, T Kartanas, D Copic, I Condado Morales, Y Zhang, PK Challa, Q Peter, T Jávorfi, R Hussain, M Dong, G Siligardi, TPJ Knowles, J Charmet
Lab on a chip
(2018)
19
(doi: 10.1039/c8lc00757h)
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
H Fu, A Possenti, R Freer, Y Nakano, NC Hernandez Villegas, M Tang, PVM Cauhy, BA Lassus, S Chen, SL Fowler, HY Figueroa, ED Huey, GVW Johnson, M Vendruscolo, KE Duff
Nat Neurosci
(2018)
22
(doi: 10.1038/s41593-018-0298-7)
Yusuf Hamied Department of Chemistry
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