Centre for Misfolding Diseases

Publications

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  • Currently displaying 821 - 840 of 2453 publications
Author(s)
Publication title
Journal Name
Publication year
Modulating the Mechanical Performance of Macroscale Fibers through Shear-Induced Alignment and Assembly of Protein Nanofibrils.
A Kamada, A Levin, Z Toprakcioglu, Y Shen, V Lutz-Bueno, KN Baumann, P Mohammadi, MB Linder, R Mezzenga, TPJ Knowles
Small
(2019)
16
(doi: 10.1002/smll.201904190)
Autoantibodies against the prion protein in individuals with PRNP mutations
K Frontzek, M Carta, M Losa, M Epskamp, G Meisl, A Anane, J-P Brandel, U Camenisch, J Castilla, S Haïk, T Knowles, E Lindner, A Lutterotti, EV Minikel, I Roiter, JG Safar, R Sanchez-Valle, D Žáková, S Hornemann, A Aguzzi
medRxiv
(2019)
(doi: 10.1101/19007773)
Autocatalytic amplification of Alzheimer-associated Aβ42 peptide aggregation in human cerebrospinal fluid.
R Frankel, M Törnquist, G Meisl, O Hansson, U Andreasson, H Zetterberg, K Blennow, B Frohm, T Cedervall, TPJ Knowles, T Leiding, S Linse
Communications biology
(2019)
2
(doi: 10.1038/s42003-019-0612-2)
A New Platform for Drug Discovery
TP Knowles
Future Drug Discovery
(2019)
1
(doi: 10.4155/fdd-2019-0030)
Probing the dynamic stalk region of the ribosome using solution NMR.
X Wang, JP Kirkpatrick, HMM Launay, A de Simone, D Häussinger, CM Dobson, M Vendruscolo, LD Cabrita, CA Waudby, J Christodoulou
Scientific reports
(2019)
9
(doi: 10.1038/s41598-019-49190-1)
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y-C Liao, M Fernandopulle, G Wang, H Choi, L Hao, CM Drerup, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, M Nelson, M Czekalska, G Musteikyte, R Patel, C Stephens, A Pasolli, L Forrest, PS George-Hyslop, J Lippincott-Schwartz, ME Ward
Cell
(2019)
179
(doi: 10.1016/j.cell.2019.08.050)
Characterizing individual protein aggregates by infrared nanospectroscopy and atomic force microscopy
FS Ruggeri, T Šneideris, S Chia, M Vendruscolo, TPJ Knowles
JoVE
(2019)
2019
(doi: 10.3791/60108)
Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy
FS Ruggeri, T Šneideris, S Chia, M Vendruscolo, TPJ Knowles
Journal of Visualized Experiments
(2019)
(doi: 10.3791/60108-v)
Scalable integration of nano-, and microfluidics with hybrid 2-photon lithography
O Vanderpoorten, Q Peter, PK Challa, UF Keyser, J Baumberg, CF Kaminski, TPJ Knowles
Microsystems & nanoengineering
(2019)
5
(doi: 10.1038/s41378-019-0080-3)
Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity.
A Achour, L Broggini, X Han, R Sun, C Santambrogio, J Buratto, C Visentin, A Barbiroli, CMG De Luca, P Sormanni, F Moda, A De Simone, T Sandalova, R Grandori, C Camilloni, S Ricagno
The FEBS journal
(2019)
287
(doi: 10.1111/febs.15046)
Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification.
PR Lindstedt, FA Aprile, MJ Matos, M Perni, JB Bertoldo, B Bernardim, Q Peter, G Jiménez-Osés, TPJ Knowles, CM Dobson, F Corzana, M Vendruscolo, GJL Bernardes
ACS central science
(2019)
5
(doi: 10.1021/acscentsci.9b00467)
An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils
ED Agerschou, P Flagmeier, T Saridaki, C Galvagnion, D Komnig, L Heid, V Prasad, H Shaykhalishahi, D Willbold, CM Dobson, A Voigt, B Falkenburger, W Hoyer, AK Buell
eLife
(2019)
8
(doi: 10.7554/eLife.46112)
Evaluation of linker length effects on a BET bromodomain probe.
R Traquete, E Henderson, S Picaud, PMSD Cal, F Sieglitz, T Rodrigues, R Oliveira, P Filippakopoulos, GJL Bernardes
Chemical Communications
(2019)
55
(doi: 10.1039/c9cc05054j)
A Practical Guide to the Simultaneous Determination of Protein Structure and Dynamics Using Metainference
T Löhr, C Camilloni, M Bonomi, M Vendruscolo
Methods in molecular biology (Clifton, N.J.)
(2019)
2022
(doi: 10.1007/978-1-4939-9608-7_13)
Ethynylbenziodoxolone Reactivity in Cysteine Bioconjugation
SR Adusumalli, GJL Bernardes
Chem
(2019)
5
(doi: 10.1016/j.chempr.2019.07.014)
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
GT Heller, FA Aprile, TCT Michaels, R Limbocker, M Perni, FS Ruggeri, B Mannini, T Löhr, M Bonomi, C Camilloni, A De Simone, IC Felli, R Pierattelli, TPJ Knowles, CM Dobson, M Vendruscolo
(2019)
(doi: 10.1101/729392)
The Hsp70 Chaperone System Stabilizes a Thermo-sensitive Subproteome in E. coli
L Zhao, G Vecchi, M Vendruscolo, R Körner, M Hayer-Hartl, FU Hartl
Cell Reports
(2019)
28
(doi: 10.1016/j.celrep.2019.06.081)
Promoting transparency and reproducibility in enhanced molecular simulations
PLUMED consortium
Nature Methods
(2019)
16
(doi: 10.1038/s41592-019-0506-8)
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression.
S De, DR Whiten, FS Ruggeri, C Hughes, M Rodrigues, DI Sideris, CG Taylor, FA Aprile, S Muyldermans, TPJ Knowles, M Vendruscolo, C Bryant, K Blennow, I Skoog, S Kern, H Zetterberg, D Klenerman
Acta Neuropathologica Communications
(2019)
7
(doi: 10.1186/s40478-019-0777-4)
Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers.
B Mannini, G Vecchi, A Labrador-Garrido, B Fabre, G Fani, JM Franco, K Lilley, D Pozo, M Vendruscolo, F Chiti, CM Dobson, C Roodveldt
ACS Chem Neurosci
(2019)
10
(doi: 10.1021/acschemneuro.9b00088)
Yusuf Hamied Department of Chemistry
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