Centre for Misfolding Diseases

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  • Currently displaying 821 - 840 of 2508 publications
Author(s)
Publication title
Journal Name
Publication year
Autoantibodies against the prion protein in individuals with PRNP mutations
K Frontzek, M Carta, M Losa, M Epskamp, G Meisl, A Anane, J-P Brandel, U Camenisch, J Castilla, S Haïk, T Knowles, E Lindner, A Lutterotti, EV Minikel, I Roiter, JG Safar, R Sanchez-Valle, D Žáková, S Hornemann, A Aguzzi, THAUTAN-MC Study Group
Neurology
(2020)
95
(doi: 10.1212/wnl.0000000000009183)
A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation
R Kundra, CM Dobson, M Vendruscolo
iScience
(2020)
23
(doi: 10.1016/j.isci.2020.100934)
Thermodynamic and kinetic design principles for protein aggregation inhibitors
TCT Michaels, A Šarić, G Meisl, GT Heller, S Curk, P Arosio, S Linse, CM Dobson, M Vendruscolo, TPJ Knowles
(2020)
(doi: 10.1101/2020.02.22.960716)
A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases
MA Metrick, NDC Ferreira, E Saijo, A Kraus, K Newell, G Zanusso, M Vendruscolo, B Ghetti, B Caughey
Acta Neuropathol Commun
(2020)
8
(doi: 10.1186/s40478-020-0887-z)
The molecular processes underpinning prion-like spreading and seed amplification in protein aggregation.
G Meisl, TP Knowles, D Klenerman
Current opinion in neurobiology
(2020)
61
(doi: 10.1016/j.conb.2020.01.010)
Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation.
E Gil de Montes, A Istrate, CD Navo, E Jiménez-Moreno, EA Hoyt, F Corzana, I Robina, G Jiménez-Osés, AJ Moreno-Vargas, GJL Bernardes
Angew Chem Int Ed Engl
(2020)
59
(doi: 10.1002/anie.201914529)
Lipid-Stabilized Double Emulsions Generated in Planar Microfluidic Devices.
L Kong, A Levin, Z Toprakcioglu, Y Xu, H Gang, R Ye, B-Z Mu, TPJ Knowles
Langmuir
(2020)
36
(doi: 10.1021/acs.langmuir.9b03622)
Biocompatible Hybrid Organic/Inorganic Microhydrogels Promote Bacterial Adherence and Eradication in Vitro and in Vivo.
L Schnaider, Z Toprakcioglu, A Ezra, X Liu, D Bychenko, A Levin, E Gazit, TPJ Knowles
Nano Letters
(2020)
20
(doi: 10.1021/acs.nanolett.9b04290)
Polyglutamine Aggregation in a Living Animal is Governed by Biophysical Parameters
T Sinnige, T Michaels, M Vendruscolo, RI Morimoto
BIOPHYSICAL JOURNAL
(2020)
118
Attoliter protein nanogels from droplet nanofluidics for intracellular delivery
Z Toprakcioglu, PK Challa, DB Morse, T Knowles
Sci Adv
(2020)
6
(doi: 10.1126/sciadv.aay7952)
Molecular Forces in the Liquid-Liquid Phase Separation of Biomolecules
TJ Welsh, G Krainer, TP Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2134)
Rational Design of Conformation-Specific Antibodies for Tau Oligomers
K Kulenkampff, FA Aprile, P Sormanni, RT Ranasinghe, D Klenerman, M Vendruscolo
BIOPHYSICAL JOURNAL
(2020)
118
Quantifying the Thermodynamic Stability of Amyloid Fibrils
KL Callaghan, Q Peter, JR Kumita, TP Knowles, CM Dobson
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2725)
Microfluidic Diffusional Sizing for Studying Protein-Protein Interactions
MM Schneider, T Scheidt, CM Dobson, TPJ Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2818)
Investigation of Natural and Synthetic Aggregation Inhibitors using Microfluidic Applications
T Scheidt, J Carozza, JL Benesch, P Arosio, S Linse, TPJ Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.1878)
Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid‑β Peptide Aggregation and Reduces the Toxicity of Its Oligomers
SA Ghadami, S Chia, FS Ruggeri, G Meisl, F Bemporad, J Habchi, R Cascella, CM Dobson, M Vendruscolo, TPJ Knowles, F Chiti
Biomacromolecules
(2020)
21
(doi: 10.1021/acs.biomac.9b01475)
A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles
WK Man, A De Simone, JD Barritt, M Vendruscolo, CM Dobson, G Fusco
Frontiers in Neuroscience
(2020)
14
(doi: 10.3389/fnins.2020.00018)
Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition
Y Shen, FS Ruggeri, D Vigolo, A Kamada, S Qamar, A Levin, C Iserman, S Alberti, P St George-Hyslop, TPJ Knowles
(2020)
(doi: 10.1101/2020.01.21.912857)
The catalytic nature of protein aggregation.
AJ Dear, G Meisl, TCT Michaels, MR Zimmermann, S Linse, TPJ Knowles
The Journal of chemical physics
(2020)
152
(doi: 10.1063/1.5133635)
Coating and Stabilization of Liposomes by Clathrin-Inspired DNA Self-Assembly
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S Hernández-Ainsa
ACS nano
(2020)
14
(doi: 10.1021/acsnano.9b09453)
Yusuf Hamied Department of Chemistry
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