Centre for Misfolding Diseases

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  • Currently displaying 821 - 840 of 2484 publications
Author(s)
Publication title
Journal Name
Publication year
Rational Design of Conformation-Specific Antibodies for Tau Oligomers
K Kulenkampff, FA Aprile, P Sormanni, RT Ranasinghe, D Klenerman, M Vendruscolo
BIOPHYSICAL JOURNAL
(2020)
118
Polyglutamine Aggregation in a Living Animal is Governed by Biophysical Parameters
T Sinnige, T Michaels, M Vendruscolo, RI Morimoto
BIOPHYSICAL JOURNAL
(2020)
118
Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers
SA Ghadami, S Chia, FS Ruggeri, G Meisl, F Bemporad, J Habchi, R Cascella, CM Dobson, M Vendruscolo, TPJ Knowles, F Chiti
Biomacromolecules
(2020)
21
(doi: 10.1021/acs.biomac.9b01475)
A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles.
WK Man, A De Simone, JD Barritt, M Vendruscolo, CM Dobson, G Fusco
Frontiers in neuroscience
(2020)
14
(doi: 10.3389/fnins.2020.00018)
Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition
Y Shen, FS Ruggeri, D Vigolo, A Kamada, S Qamar, A Levin, C Iserman, S Alberti, P St George-Hyslop, TPJ Knowles
(2020)
(doi: 10.1101/2020.01.21.912857)
The catalytic nature of protein aggregation
AJ Dear, G Meisl, TCT Michaels, MR Zimmermann, S Linse, TPJ Knowles
The Journal of chemical physics
(2020)
152
(doi: 10.1063/1.5133635)
Coating and Stabilization of Liposomes by Clathrin-Inspired DNA Self-Assembly
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S Hernández-Ainsa
ACS Nano
(2020)
14
(doi: 10.1021/acsnano.9b09453)
Chris Dobson (1949-2019) Obituary
TPJ Knowles, M Vendruscolo
Nature chemical biology
(2020)
16
(doi: 10.1038/s41589-019-0456-6)
Widespread remodeling of proteome solubility in response to different protein homeostasis stresses
X Sui, DEV Pires, AR Ormsby, D Cox, S Nie, G Vecchi, M Vendruscolo, DB Ascher, GE Reid, DM Hatters
Proceedings of the National Academy of Sciences
(2020)
117
(doi: 10.1073/pnas.1912897117)
The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State
M Runfola, A De Simone, M Vendruscolo, CM Dobson, G Fusco
Scientific reports
(2020)
10
(doi: 10.1038/s41598-019-57023-4)
Dynamics of oligomer populations formed during the aggregation of Alzheimer’s A β 42 peptide
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, M Vendruscolo, CM Dobson, S Linse, TPJ Knowles
(2020)
(doi: 10.1101/2020.01.08.897488)
A microfluidic strategy for the detection of membrane protein interactions
Y Zhang, TW Herling, S Kreida, QAE Peter, T Kartanas, S Törnroth-Horsefield, S Linse, TPJ Knowles
Lab on a chip
(2020)
20
(doi: 10.1039/d0lc00205d)
Local micro and nano patterning of microfluidic devices using the solid on liquid deposition process
J Charmet, A Homsy, M Wood, J Covington, L Isa, M Textor, TPJ Knowles, H Keppner
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences Microtas 2017
(2020)
Making biological membrane resistant to the toxicity of misfolded protein oligomers: a lesson from trodusquemine
S Errico, G Lucchesi, D Odino, S Muscat, C Capitini, C Bugelli, C Canale, R Ferrando, G Grasso, D Barbut, M Calamai, A Danani, M Zasloff, A Relini, G Caminati, M Vendruscolo, F Chiti
Nanoscale
(2020)
12
(doi: 10.1039/d0nr05285j)
Correction: Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GJL Bernandes, TPJ Knowles
Soft matter
(2020)
16
(doi: 10.1039/d0sm90059a)
Proteome-wide observation of the phenomenon of life on the edge of solubility.
G Vecchi, P Sormanni, B Mannini, A Vandelli, GG Tartaglia, CM Dobson, FU Hartl, M Vendruscolo
Proceedings of the National Academy of Sciences
(2019)
117
(doi: 10.1073/pnas.1910444117)
Physical mechanisms of amyloid nucleation on fluid membranes
J Krausser, TPJ Knowles, A Šarić
(2019)
(doi: 10.1101/2019.12.22.886267)
Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains.
M Maritan, M Romeo, L Oberti, P Sormanni, M Tasaki, R Russo, A Ambrosetti, P Motta, P Rognoni, G Mazzini, A Barbiroli, G Palladini, M Vendruscolo, L Diomede, M Bolognesi, G Merlini, F Lavatelli, S Ricagno
Journal of molecular biology
(2019)
432
(doi: 10.1016/j.jmb.2019.12.015)
Homage to Chris Dobson.
J Baum, F Chiti, A De Simone, TPJ Knowles, JR Kumita, SE Radford, CV Robinson, X Salvatella, K Valelli, M Vendruscolo, A Pastore, GG Tartaglia
Frontiers in molecular biosciences
(2019)
6
(doi: 10.3389/fmolb.2019.00137)
Determination of a Structural Ensemble Representing the Dynamics of a G-Quadruplex DNA
G Portella, M Orozco, M Vendruscolo
Biochemistry
(2019)
59
(doi: 10.1021/acs.biochem.9b00493)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
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