Centre for Misfolding Diseases

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  • Currently displaying 801 - 820 of 2398 publications
Author(s)
Publication title
Journal Name
Publication year
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y-C Liao, M Fernandopulle, G Wang, H Choi, L Hao, CM Drerup, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, M Nelson, M Czekalska, G Musteikyte, R Patel, C Stephens, A Pasolli, L Forrest, PS George-Hyslop, J Lippincott-Schwartz, ME Ward
(2019)
(doi: 10.2139/ssrn.3312723)
The presence of autoantibodies against the prion protein is independent of PRNP mutations
K Frontzek, M Carta, M Losa, M Epskamp, G Meisl, U Camenisch, T Knowles, S Hornemann, A Aguzzi
PRION
(2019)
13
Oligomer Diversity during the Aggregation of the Repeat Region of Tau.
M Kjaergaard, AJ Dear, F Kundel, S Qamar, G Meisl, TPJ Knowles, D Klenerman
ACS Chemical Neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00250)
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions.
B Mannini, J Habchi, S Chia, FS Ruggeri, M Perni, TPJ Knowles, CM Dobson, M Vendruscolo
ACS Chem Neurosci
(2018)
9
(doi: 10.1021/acschemneuro.8b00141)
Resolving protein mixtures using microfluidic diffusional sizing combined with synchrotron radiation circular dichroism.
C Bortolini, T Kartanas, D Copic, I Condado Morales, Y Zhang, PK Challa, Q Peter, T Jávorfi, R Hussain, M Dong, G Siligardi, TPJ Knowles, J Charmet
Lab on A Chip
(2018)
19
(doi: 10.1039/c8lc00757h)
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology.
H Fu, A Possenti, R Freer, Y Nakano, NC Hernandez Villegas, M Tang, PVM Cauhy, BA Lassus, S Chen, SL Fowler, HY Figueroa, ED Huey, GVW Johnson, M Vendruscolo, KE Duff
Nat Neurosci
(2018)
22
(doi: 10.1038/s41593-018-0298-7)
Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming
N Ahmed, P Sormanni, P Ciryam, M Vendruscolo, C Dobson, E O’Brien
(2018)
(doi: 10.1101/490755)
Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale.
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
Nano Lett
(2018)
18
(doi: 10.1021/acs.nanolett.8b02916)
One-pot stapling of interchain disulfides of antibodies using an isobutylene motif
S Sun, P Akkapeddi, MC Marques, N Martínez-Sáez, VM Torres, C Cordeiro, O Boutureira, GJL Bernardes
Org Biomol Chem
(2018)
17
(doi: 10.1039/c8ob02877j)
Protein engineering through chemical, genetic and computational manipulation
I Hamachi, GJL Bernardes
Chemical Society Reviews
(2018)
47
(doi: 10.1039/c8cs90125b)
Attentive Cross-Modal Paratope Prediction.
A Deac, P VeliČković, P Sormanni
J Comput Biol
(2018)
26
(doi: 10.1089/cmb.2018.0175)
Image-Assisted Microvessel-on-a-Chip Platform for Studying Cancer Cell Transendothelial Migration Dynamics
C Bertulli, M Gerigk, N Piano, Y Liu, D Zhang, T Müller, TJ Knowles, YYS Huang
Sci Rep
(2018)
8
(doi: 10.1038/s41598-018-30776-0)
Bioorthogonal decaging reactions for targeted drug activation
S Davies, BJ Stenton, GJL Bernardes
Chimia
(2018)
72
(doi: 10.2533/chimia.2018.771)
Mechanobiology of Protein Droplets: Force Arises from Disorder
TJ Welsh, Y Shen, A Levin, TPJ Knowles
Cell
(2018)
175
(doi: 10.1016/j.cell.2018.11.020)
Determination of Structural Ensembles of Proteins: Restraining vs Reweighting.
R Rangan, M Bonomi, GT Heller, A Cesari, G Bussi, M Vendruscolo
Journal of chemical theory and computation
(2018)
14
(doi: 10.1021/acs.jctc.8b00738)
Quantifying Co-Oligomer Formation by α‑Synuclein
M Iljina, AJ Dear, GA Garcia, S De, L Tosatto, P Flagmeier, DR Whiten, TCT Michaels, D Frenkel, CM Dobson, TPJ Knowles, D Klenerman
ACS Nano
(2018)
12
(doi: 10.1021/acsnano.8b03575)
Radical‐Mediated Thiol‐Ene Strategy: Photoactivation of Thiol‐Containing Drugs in Cancer Cells
GJ Lopes Bernardes
Angewandte Chemie - International Edition
(2018)
57
(doi: 10.1002/ange.201811338)
Modular Pore-Forming Immunotoxins with Caged Cytotoxicity Tailored by Directed Evolution
NL Mutter, M Soskine, G Huang, IS Albuquerque, GJL Bernardes, G Maglia
ACS chemical biology
(2018)
13
(doi: 10.1021/acschembio.8b00720)
Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools.
L Shan, N Mody, P Sormani, KL Rosenthal, MM Damschroder, R Esfandiary
Mol Pharm
(2018)
15
(doi: 10.1021/acs.molpharmaceut.8b00867)
Cisplatin-Triggered Bioorthogonal Decaging of Amide Bonds for Targeted-Drug Activation in vivo
B Stenton, B Oliveira, J Conde, M Negrão, M Godinho Ferreira, R Fior, G Bernardes
(2018)
(doi: 10.26434/chemrxiv.7327904.v1)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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