Centre for Misfolding Diseases

Publications

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  • Currently displaying 781 - 800 of 2450 publications
Author(s)
Publication title
Journal Name
Publication year
Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid‑β Peptide Aggregation and Reduces the Toxicity of Its Oligomers
SA Ghadami, S Chia, FS Ruggeri, G Meisl, F Bemporad, J Habchi, R Cascella, CM Dobson, M Vendruscolo, TPJ Knowles, F Chiti
Biomacromolecules
(2020)
21
(doi: 10.1021/acs.biomac.9b01475)
Quantifying the Thermodynamic Stability of Amyloid Fibrils
KL Callaghan, Q Peter, JR Kumita, TP Knowles, CM Dobson
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2725)
Molecular Forces in the Liquid-Liquid Phase Separation of Biomolecules
TJ Welsh, G Krainer, TP Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2134)
Microfluidic Diffusional Sizing for Studying Protein-Protein Interactions
MM Schneider, T Scheidt, CM Dobson, TPJ Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2818)
Investigation of Natural and Synthetic Aggregation Inhibitors using Microfluidic Applications
T Scheidt, J Carozza, JL Benesch, P Arosio, S Linse, TPJ Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.1878)
A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles
WK Man, A De Simone, JD Barritt, M Vendruscolo, CM Dobson, G Fusco
Front Neurosci
(2020)
14
(doi: 10.3389/fnins.2020.00018)
The catalytic nature of protein aggregation.
AJ Dear, G Meisl, TCT Michaels, MR Zimmermann, S Linse, TPJ Knowles
Journal of Chemical Physics
(2020)
152
(doi: 10.1063/1.5133635)
Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition
Y Shen, FS Ruggeri, D Vigolo, A Kamada, S Qamar, A Levin, C Iserman, S Alberti, P St George-Hyslop, TPJ Knowles
(2020)
(doi: 10.1101/2020.01.21.912857)
Coating and Stabilization of Liposomes by Clathrin-Inspired DNA Self-Assembly.
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S Hernández-Ainsa
ACS Nano
(2020)
14
(doi: 10.1021/acsnano.9b09453)
Chris Dobson (1949-2019).
TPJ Knowles, M Vendruscolo
Nature Chemical Biology
(2020)
16
(doi: 10.1038/s41589-019-0456-6)
Widespread remodeling of proteome solubility in response to different protein homeostasis stresses
X Sui, DEV Pires, AR Ormsby, D Cox, S Nie, G Vecchi, M Vendruscolo, DB Ascher, GE Reid, DM Hatters
Proc Natl Acad Sci U S A
(2020)
117
(doi: 10.1073/pnas.1912897117)
The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State
M Runfola, A De Simone, M Vendruscolo, CM Dobson, G Fusco
Scientific reports
(2020)
10
(doi: 10.1038/s41598-019-57023-4)
Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, M Vendruscolo, CM Dobson, S Linse, TPJ Knowles
(2020)
(doi: 10.1101/2020.01.08.897488)
Polyglutamine Aggregation in a Living Animal is Governed by Biophysical Parameters
T Sinnige, T Michaels, M Vendruscolo, RI Morimoto
BIOPHYSICAL JOURNAL
(2020)
118
Local micro and nano patterning of microfluidic devices using the solid on liquid deposition process
J Charmet, A Homsy, M Wood, J Covington, L Isa, M Textor, TPJ Knowles, H Keppner
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences Microtas 2017
(2020)
A microfluidic strategy for the detection of membrane protein interactions
Y Zhang, TW Herling, S Kreida, QAE Peter, T Kartanas, S Törnroth-Horsefield, S Linse, TPJ Knowles
Lab on A Chip
(2020)
20
(doi: 10.1039/d0lc00205d)
Making biological membrane resistant to the toxicity of misfolded protein oligomers: a lesson from trodusquemine.
S Errico, G Lucchesi, D Odino, S Muscat, C Capitini, C Bugelli, C Canale, R Ferrando, G Grasso, D Barbut, M Calamai, A Danani, M Zasloff, A Relini, G Caminati, M Vendruscolo, F Chiti
Nanoscale
(2020)
12
(doi: 10.1039/d0nr05285j)
Correction: Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions.
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GJL Bernandes, TPJ Knowles
Soft Matter
(2020)
16
(doi: 10.1039/d0sm90059a)
Rational Design of Conformation-Specific Antibodies for Tau Oligomers
K Kulenkampff, FA Aprile, P Sormanni, RT Ranasinghe, D Klenerman, M Vendruscolo
BIOPHYSICAL JOURNAL
(2020)
118
Proteome-wide observation of the phenomenon of life on the edge of solubility
G Vecchi, P Sormanni, B Mannini, A Vandelli, GG Tartaglia, CM Dobson, FU Hartl, M Vendruscolo
Proc Natl Acad Sci U S A
(2019)
117
(doi: 10.1073/pnas.1910444117)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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