Centre for Misfolding Diseases

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  • Currently displaying 781 - 800 of 2486 publications
Author(s)
Publication title
Journal Name
Publication year
Ultrastructural evidence for self-replication of alzheimer-associated Aβ42 amyloid along the sides of fibrils
M Törnquist, R Cukalevski, U Weininger, G Meisl, TPJ Knowles, T Leiding, A Malmendal, M Akke, S Linse
Proceedings of the National Academy of Sciences of the United States of America
(2020)
117
(doi: 10.1073/pnas.1918481117)
Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform
M Koopman, Q Peter, RI Seinstra, M Perni, M Vendruscolo, CM Dobson, TPJ Knowles, EAA Nollen
Nature Protocols
(2020)
15
(doi: 10.1038/s41596-020-0321-9)
Kinetic diversity of amyloid oligomers.
AJ Dear, TCT Michaels, G Meisl, D Klenerman, S Wu, S Perrett, S Linse, CM Dobson, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2020)
117
(doi: 10.1073/pnas.1922267117)
A Sweet Galactose Transfer: Metabolic Oligosaccharide Engineering as a Tool To Study Glycans in Plasmodium Infection
A Kitowski, GJL Bernardes
Chembiochem
(2020)
21
(doi: 10.1002/cbic.202000226)
Brain-Sparing Sympathofacilitators Mitigate Obesity without Adverse Cardiovascular Effects
I Mahú, A Barateiro, E Rial-Pensado, N Martinéz-Sánchez, SH Vaz, PMSD Cal, B Jenkins, T Rodrigues, C Cordeiro, MF Costa, R Mendes, E Seixas, MMA Pereira, N Kubasova, V Gres, I Morris, C Temporão, M Olivares, Y Sanz, A Koulman, F Corzana, AM Sebastião, M López, GJL Bernardes, AI Domingos
Cell Metab
(2020)
31
(doi: 10.1016/j.cmet.2020.04.013)
The antidiabetic drug lobeglitazone has the potential to inhibit PTP1B activity.
RF Rocha, T Rodrigues, ACO Menegatti, GJL Bernardes, H Terenzi
Bioorg Chem
(2020)
100
(doi: 10.1016/j.bioorg.2020.103927)
Editorial overview: Toward smart medicines
GJL Bernardes, R Rodriguez
Curr Opin Chem Biol
(2020)
56
(doi: 10.1016/j.cbpa.2020.04.011)
A kinetic ensemble of the Alzheimer’s Aβ peptide
T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo
(2020)
(doi: 10.1101/2020.05.07.082818)
Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
BIOPHYSICAL JOURNAL
(2020)
120
(doi: 10.1101/2020.05.04.076299)
Precise Installation of Diazo-Tagged Side-Chains on Proteins to Enable In Vitro and In-Cell Site-Specific Labeling
B Bernardim, L Dunsmore, H Li, B Hocking, R Nuñez-Franco, CD Navo, G Jiménez-Osés, ACB Burtoloso, GJL Bernardes
Bioconjugate Chemistry
(2020)
31
(doi: 10.1021/acs.bioconjchem.0c00232)
A Microfluidic Co-Flow Route for Human Serum Albumin-Drug-Nanoparticle Assembly.
TA Hakala, S Davies, Z Toprakcioglu, B Bernardim, GJL Bernardes, TPJ Knowles
Chemistry A European Journal
(2020)
26
(doi: 10.1002/chem.202001146)
Surface electrostatics govern the emulsion stability of biomolecular condensates
TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
(2020)
(doi: 10.1101/2020.04.20.047910)
Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment.
IA Bermejo, CD Navo, J Castro-López, A Guerreiro, E Jiménez-Moreno, EM Sánchez Fernández, F García-Martín, H Hinou, S-I Nishimura, JM García Fernández, CO Mellet, A Avenoza, JH Busto, GJL Bernardes, R Hurtado-Guerrero, JM Peregrina, F Corzana
Chemical science
(2020)
11
(doi: 10.1039/c9sc06334j)
Author Correction: Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide (Nature Chemistry, (2020), 12, 5, (445-451), 10.1038/s41557-020-0452-1)
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, CM Dobson, M Vendruscolo, S Linse, TPJ Knowles
Nature Chemistry
(2020)
12
(doi: 10.1038/s41557-020-0468-6)
Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide.
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, CM Dobson, M Vendruscolo, S Linse, TPJ Knowles
Nature chemistry
(2020)
12
(doi: 10.1038/s41557-020-0452-1)
Mechanism of droplet-formation in a supersonic microfluidic spray device
T Kartanas, Z Toprakcioglu, TA Hakala, A Levin, TW Herling, R Daly, J Charmet, TPJ Knowles
Applied Physics Letters
(2020)
116
(doi: 10.1063/1.5145109)
Microfluidic approaches for the analysis of protein–protein interactions in solution
WE Arter, A Levin, G Krainer, TPJ Knowles
Biophysical reviews
(2020)
12
(doi: 10.1007/s12551-020-00679-4)
Stable Pyrrole‐Linked Bioconjugates through Tetrazine‐Triggered Azanorbornadiene Fragmentation
EG de Montes, A Istrate, CD Navo, E Jiménez‐Moreno, EA Hoyt, F Corzana, I Robina, G Jiménez‐Osés, AJ Moreno‐Vargas, GJL Bernardes
Angewandte Chemie
(2020)
132
(doi: 10.1002/ange.201914529)
Complexity in Lipid Membrane Composition Induces Resilience to Aβ42 Aggregation.
M Sanguanini, KN Baumann, S Preet, S Chia, J Habchi, TPJ Knowles, M Vendruscolo
ACS Chem Neurosci
(2020)
11
(doi: 10.1021/acschemneuro.0c00101)
Ultrathin Polydopamine Films with Phospholipid Nanodiscs Containing a Glycophorin A Domain
TM D'Alvise, S Harvey, L Hueske, J Szelwicka, L Veith, TPJ Knowles, D Kubiczek, C Flaig, F Port, K Gottschalk, F Rosenau, B Graczykowski, G Fytas, FS Ruggeri, K Wunderlich, T Weil
Advanced Functional Materials
(2020)
30
(doi: 10.1002/adfm.202000378)
Yusuf Hamied Department of Chemistry
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