Centre for Misfolding Diseases

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  • Currently displaying 781 - 800 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils.
ED Agerschou, P Flagmeier, T Saridaki, C Galvagnion, D Komnig, L Heid, V Prasad, H Shaykhalishahi, D Willbold, CM Dobson, A Voigt, B Falkenburger, W Hoyer, AK Buell
eLife
(2019)
8
(doi: 10.7554/elife.46112)
Evaluation of linker length effects on a BET bromodomain probe.
R Traquete, E Henderson, S Picaud, PMSD Cal, F Sieglitz, T Rodrigues, R Oliveira, P Filippakopoulos, GJL Bernardes
Chemical communications (Cambridge, England)
(2019)
55
(doi: 10.1039/c9cc05054j)
A Practical Guide to the Simultaneous Determination of Protein Structure and Dynamics Using Metainference
T Löhr, C Camilloni, M Bonomi, M Vendruscolo
Methods Mol Biol
(2019)
2022
(doi: 10.1007/978-1-4939-9608-7_13)
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
GT Heller, FA Aprile, TCT Michaels, R Limbocker, M Perni, FS Ruggeri, B Mannini, T Löhr, M Bonomi, C Camilloni, A De Simone, IC Felli, R Pierattelli, TPJ Knowles, CM Dobson, M Vendruscolo
(2019)
(doi: 10.1101/729392)
Ethynylbenziodoxolone Reactivity in Cysteine Bioconjugation
SR Adusumalli, GJL Bernardes
Chem
(2019)
5
(doi: 10.1016/j.chempr.2019.07.014)
The Hsp70 Chaperone System Stabilizes a Thermo-sensitive Subproteome in E. coli
L Zhao, G Vecchi, M Vendruscolo, R Körner, M Hayer-Hartl, FU Hartl
Cell reports
(2019)
28
(doi: 10.1016/j.celrep.2019.06.081)
Promoting transparency and reproducibility in enhanced molecular simulations.
PLUMED consortium
Nature Methods
(2019)
16
(doi: 10.1038/s41592-019-0506-8)
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression
S De, DR Whiten, FS Ruggeri, C Hughes, M Rodrigues, DI Sideris, CG Taylor, FA Aprile, S Muyldermans, TPJ Knowles, M Vendruscolo, C Bryant, K Blennow, I Skoog, S Kern, H Zetterberg, D Klenerman
Acta neuropathologica communications
(2019)
7
(doi: 10.1186/s40478-019-0777-4)
Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers
B Mannini, G Vecchi, A Labrador-Garrido, B Fabre, G Fani, JM Franco, K Lilley, D Pozo, M Vendruscolo, F Chiti, CM Dobson, C Roodveldt
ACS Chem Neurosci
(2019)
10
(doi: 10.1021/acschemneuro.9b00088)
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S HERNANDEZ AINSA
(2019)
(doi: 10.26434/chemrxiv.8859017.v1)
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S HERNANDEZ AINSA
(2019)
(doi: 10.26434/chemrxiv.8859017)
Nature and Regulation of Protein Folding on the Ribosome
CA Waudby, CM Dobson, J Christodoulou
Trends in Biochemical Sciences
(2019)
44
(doi: 10.1016/j.tibs.2019.06.008)
Overexpression of osmosensitive Ca2+-activated channel TMEM63B promotes migration in HEK293T cells
MC Marques, IS Albuquerque, SH Vaz, GJL Bernardes
Biochemistry
(2019)
(doi: 10.1101/626010)
Rapid two-dimensional characterisation of proteins in solution.
KL Saar, Q Peter, T Müller, PK Challa, TW Herling, TPJ Knowles
Microsystems and Nanoengineering
(2019)
5
(doi: 10.1038/s41378-019-0072-3)
Universality of filamentous aggregation phenomena
TCT Michaels, AJ Dear, TPJ Knowles
Physical review. E
(2019)
99
(doi: 10.1103/physreve.99.062415)
In vitro and in silico activity of iridoids against leishmania amazonensis
MH Vendruscolo, GM das Neves, LP Kagami, LC Rodrigues Junior, ML Nunes Diehl, SCB Gnoatto, SA de Loreto Bordignon, PRT Romão, VL Eifler-Lima, GL von Poser
Current drug discovery technologies
(2019)
16
(doi: 10.2174/1570163814666171002102058)
Analysis of αB-crystallin polydispersity in solution through native microfluidic electrophoresis
MA Wright, FS Ruggeri, KL Saar, PK Challa, JLP Benesch, TPJ Knowles
The Analyst
(2019)
144
(doi: 10.1039/c9an00382g)
Overexpression of Osmosensitive Ca2+-Permeable Channel TMEM63B Promotes Migration in HEK293T Cells.
MC Marques, IS Albuquerque, SH Vaz, GJL Bernardes
Biochemistry
(2019)
58
(doi: 10.1021/acs.biochem.9b00224)
Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α-Synuclein and Polyglutamine in Aging Caenorhabditis elegans.
RF Laine, T Sinnige, KY Ma, AJ Haack, C Poudel, P Gaida, N Curry, M Perni, EAA Nollen, CM Dobson, M Vendruscolo, GS Kaminski Schierle, CF Kaminski
ACS chemical biology
(2019)
14
(doi: 10.1021/acschembio.9b00354)
Programmable On-Chip Artificial Cell Producing Post-Translationally Modified Ubiquitinated Protein
S Zilberzwige-Tal, A Levin, Z Toprakcioglu, TPJ Knowles, E Gazit, J Elbaz
Small (Weinheim an der Bergstrasse, Germany)
(2019)
15
(doi: 10.1002/smll.201901780)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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