Centre for Misfolding Diseases

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  • Currently displaying 661 - 680 of 2472 publications
Author(s)
Publication title
Journal Name
Publication year
Direct Digital Sensing of Proteins in Solution through Single-Molecule Optofluidics
G Krainer, KL Saar, WE Arter, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.2269)
Therapeutics Against Protein Misfolded Oligomers in Neurodegenerative Diseases
R Limbocker, A Wright, RP Kreiser, B Mannini, M Vendruscolo
BIOPHYSICAL JOURNAL
(2021)
120
TRPV2 Modulation by Small Molecules and Lipids
AD Protopopova, RA Pumroy, J de la Roche, FM Haug, BB Sousa, PN Gallo, GJL Bernardes, A Leffler, VY Moiseenkova-Bell
BIOPHYSICAL JOURNAL
(2021)
120
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition.
WK Man, B Tahirbegi, MD Vrettas, S Preet, L Ying, M Vendruscolo, A De Simone, G Fusco
Nat Commun
(2021)
12
(doi: 10.1038/s41467-021-21027-4)
Aβ Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors.
G Fani, B Mannini, G Vecchi, R Cascella, C Cecchi, CM Dobson, M Vendruscolo, F Chiti
ACS Chemical Neuroscience
(2021)
12
(doi: 10.1021/acschemneuro.0c00811)
Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions
G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.426)
One-Step Generation of Multisomes from Lipid-Stabilized Double Emulsions.
MA Czekalska, AMJ Jacobs, Z Toprakcioglu, L Kong, KN Baumann, H Gang, G Zubaite, R Ye, B Mu, A Levin, WTS Huck, TPJ Knowles
ACS Applied Materials & Interfaces
(2021)
13
(doi: 10.1021/acsami.0c16019)
Infrared Nanospectroscopy Reveals the Molecular Interaction Fingerprint of an Aggregation Inhibitor with Single Ab42 Oligomers
FS Ruggeri, J Habchi, S Chia, RI Horne, M Vendruscolo, TPJ Knowles
Nat Commun
(2021)
12
(doi: 10.1038/s41467-020-20782-0)
Label-Free Protein Analysis Using Liquid Chromatography with Gravimetric Detection
T Kartanas, A Levin, Z Toprakcioglu, T Scheidt, TA Hakala, J Charmet, TPJ Knowles
Analytical Chemistry
(2021)
93
(doi: 10.1021/acs.analchem.0c04149)
Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, S Sarwat, P Joshi, JR Kumita, S Linse, J Habchi, TPJ Knowles, B Mannini, CM Dobson, M Vendruscolo
Commun Biol
(2021)
4
(doi: 10.17863/CAM.63841)
In situ kinetic measurements of α-synuclein aggregation reveal large population of short-lived oligomers.
E Zurlo, P Kumar, G Meisl, AJ Dear, D Mondal, MMAE Claessens, TPJ Knowles, M Huber
Plos One
(2021)
16
(doi: 10.1371/journal.pone.0245548)
Facile Installation of Post-translational Modifications on the Tau Protein via Chemical Mutagenesis.
PR Lindstedt, RJ Taylor, GJL Bernardes, M Vendruscolo
ACS Chemical Neuroscience
(2021)
12
(doi: 10.1021/acschemneuro.0c00761)
A kinetic ensemble of the Alzheimer’s Aβ peptide
T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo
Nat Comput Sci
(2021)
1
(doi: 10.1038/s43588-020-00003-w)
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers.
R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, S Sarwat, P Joshi, JR Kumita, S Linse, J Habchi, TPJ Knowles, B Mannini, CM Dobson, M Vendruscolo
Communications Biology
(2021)
4
(doi: 10.1038/s42003-020-01490-3)
Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies.
MC Hardenberg, T Sinnige, S Casford, ST Dada, C Poudel, EA Robinson, M Fuxreiter, CF Kaminksi, GS Kaminski Schierle, EAA Nollen, CM Dobson, M Vendruscolo
Journal of Molecular Cell Biology
(2021)
13
(doi: 10.1093/jmcb/mjaa075)
A method of incorporating rate constants as kinetic constraints in molecular dynamics simulations.
ZF Brotzakis, M Vendruscolo, PG Bolhuis
Proceedings of the National Academy of Sciences of the United States of America
(2020)
118
(doi: 10.1073/pnas.2012423118)
Environmental Dependence of the Structure of the C-terminal Domain of the SARS-CoV-2 Envelope Protein
K Gadhave, A Kumar, P Kumar, SK Kapuganti, N Garg, M Vendruscolo, R Giri
(2020)
(doi: 10.1101/2020.12.29.424646)
Interactions of α-synuclein oligomers with lipid membranes.
G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, TPJ Knowles
Biochimica et biophysica acta. Biomembranes
(2020)
1863
(doi: 10.1016/j.bbamem.2020.183536)
Environmental Control of Amyloid Polymorphism by Modulation of Hydrodynamic Stress
J Zhou, L Venturelli, L Keiser, SK Sekatskii, F Gallaire, S Kasas, G Longo, TPJ Knowles, FS Ruggeri, G Dietler
ACS Nano
(2020)
15
(doi: 10.1021/acsnano.0c07570)
In vitro measurements of protein–protein interactions show that antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in convalescent serum
S Fiedler, MA Piziorska, V Denninger, AS Morgunov, A Ilsley, AY Malik, MM Schneider, SRA Devenish, G Meisl, A Aguzzi, H Fiegler, TPJ Knowles
(2020)
(doi: 10.1101/2020.12.20.422820)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
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