Centre for Misfolding Diseases

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  • Currently displaying 721 - 740 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation
R Kundra, CM Dobson, M Vendruscolo
iScience
(2020)
23
(doi: 10.1016/j.isci.2020.100934)
Thermodynamic and kinetic design principles for protein aggregation inhibitors
TCT Michaels, A Šarić, G Meisl, GT Heller, S Curk, P Arosio, S Linse, CM Dobson, M Vendruscolo, TPJ Knowles
(2020)
(doi: 10.1101/2020.02.22.960716)
A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases.
MA Metrick, NDC Ferreira, E Saijo, A Kraus, K Newell, G Zanusso, M Vendruscolo, B Ghetti, B Caughey
Acta Neuropathologica Communications
(2020)
8
(doi: 10.1186/s40478-020-0887-z)
The molecular processes underpinning prion-like spreading and seed amplification in protein aggregation
G Meisl, TP Knowles, D Klenerman
Curr Opin Neurobiol
(2020)
61
(doi: 10.1016/j.conb.2020.01.010)
Stable pyrrole-linked bioconjugates through tetrazine-triggered azanorbornadiene fragmentation
E Gil de Montes, A Istrate, CD Navo, E Jiménez-Moreno, EA Hoyt, F Corzana, I Robina, G Jiménez-Osés, AJ Moreno-Vargas, GJL Bernardes
Angew Chem Int Ed Engl
(2020)
59
(doi: 10.1002/anie.201914529)
Lipid-Stabilized Double Emulsions Generated in Planar Microfluidic Devices.
L Kong, A Levin, Z Toprakcioglu, Y Xu, H Gang, R Ye, B-Z Mu, TPJ Knowles
Langmuir
(2020)
36
(doi: 10.1021/acs.langmuir.9b03622)
Biocompatible Hybrid Organic/Inorganic Microhydrogels Promote Bacterial Adherence and Eradication in Vitro and in Vivo.
L Schnaider, Z Toprakcioglu, A Ezra, X Liu, D Bychenko, A Levin, E Gazit, TPJ Knowles
Nano Lett
(2020)
20
(doi: 10.1021/acs.nanolett.9b04290)
Attoliter protein nanogels from droplet nanofluidics for intracellular delivery.
Z Toprakcioglu, PK Challa, DB Morse, T Knowles
Science advances
(2020)
6
(doi: 10.1126/sciadv.aay7952)
Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid‑β Peptide Aggregation and Reduces the Toxicity of Its Oligomers
SA Ghadami, S Chia, FS Ruggeri, G Meisl, F Bemporad, J Habchi, R Cascella, CM Dobson, M Vendruscolo, TPJ Knowles, F Chiti
Biomacromolecules
(2020)
21
(doi: 10.1021/acs.biomac.9b01475)
Quantifying the Thermodynamic Stability of Amyloid Fibrils
KL Callaghan, Q Peter, JR Kumita, TP Knowles, CM Dobson
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2725)
Molecular Forces in the Liquid-Liquid Phase Separation of Biomolecules
TJ Welsh, G Krainer, TP Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2134)
Microfluidic Diffusional Sizing for Studying Protein-Protein Interactions
MM Schneider, T Scheidt, CM Dobson, TPJ Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2818)
Investigation of Natural and Synthetic Aggregation Inhibitors using Microfluidic Applications
T Scheidt, J Carozza, JL Benesch, P Arosio, S Linse, TPJ Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.1878)
A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles.
WK Man, A De Simone, JD Barritt, M Vendruscolo, CM Dobson, G Fusco
Front Neurosci
(2020)
14
(doi: 10.3389/fnins.2020.00018)
The catalytic nature of protein aggregation
AJ Dear, G Meisl, TCT Michaels, MR Zimmermann, S Linse, TPJ Knowles
The Journal of Chemical Physics
(2020)
152
(doi: 10.1063/1.5133635)
Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition
Y Shen, FS Ruggeri, D Vigolo, A Kamada, S Qamar, A Levin, C Iserman, S Alberti, P St George-Hyslop, TPJ Knowles
(2020)
(doi: 10.1101/2020.01.21.912857)
Coating and Stabilization of Liposomes by Clathrin-Inspired DNA Self-Assembly.
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S Hernández-Ainsa
ACS nano
(2020)
14
(doi: 10.1021/acsnano.9b09453)
Chris Dobson (1949–2019)
TPJ Knowles, M Vendruscolo
Nature Chemical Biology
(2020)
16
(doi: 10.1038/s41589-019-0456-6)
Widespread remodeling of proteome solubility in response to different protein homeostasis stresses.
X Sui, DEV Pires, AR Ormsby, D Cox, S Nie, G Vecchi, M Vendruscolo, DB Ascher, GE Reid, DM Hatters
Proceedings of the National Academy of Sciences
(2020)
117
(doi: 10.1073/pnas.1912897117)
The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State
M Runfola, A De Simone, M Vendruscolo, CM Dobson, G Fusco
Sci Rep
(2020)
10
(doi: 10.1038/s41598-019-57023-4)
Yusuf Hamied Department of Chemistry
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