Centre for Misfolding Diseases

Publications

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  • Currently displaying 721 - 740 of 2398 publications
Author(s)
Publication title
Journal Name
Publication year
An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils
ED Agerschou, P Flagmeier, T Saridaki, C Galvagnion, D Komnig, L Heid, V Prasad, H Shaykhalishahi, D Willbold, CM Dobson, A Voigt, B Falkenburger, W Hoyer, AK Buell
Elife
(2019)
8
(doi: 10.7554/eLife.46112)
Evaluation of linker length effects on a BET bromodomain probe.
R Traquete, E Henderson, S Picaud, PMSD Cal, F Sieglitz, T Rodrigues, R Oliveira, P Filippakopoulos, GJL Bernardes
Chemical Communications
(2019)
55
(doi: 10.1039/c9cc05054j)
A Practical Guide to the Simultaneous Determination of Protein Structure and Dynamics Using Metainference.
T Löhr, C Camilloni, M Bonomi, M Vendruscolo
Methods Mol Biol
(2019)
2022
(doi: 10.1007/978-1-4939-9608-7_13)
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
G Heller, F Aprile, T Michaels, R Limbocker, M Perni, FS Ruggeri, B Mannini, T Löhr, M Bonomi, C Camilloni, A De Simone, I Felli, R Pierattelli, T Knowles, C Dobson, M Vendruscolo
(2019)
(doi: 10.1101/729392)
Ethynylbenziodoxolone Reactivity in Cysteine Bioconjugation
SR Adusumalli, GJL Bernardes
Chem
(2019)
5
(doi: 10.1016/j.chempr.2019.07.014)
Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers
B Mannini, G Vecchi, A Labrador-Garrido, B Fabre, G Fani, JM Franco, K Lilley, D Pozo, M Vendruscolo, F Chiti, CM Dobson, C Roodveldt
ACS Chemical Neuroscience
(2019)
10
(doi: 10.1021/acschemneuro.9b00088)
The Hsp70 Chaperone System Stabilizes a Thermo-sensitive Subproteome in E. coli
L Zhao, G Vecchi, M Vendruscolo, R Körner, M Hayer-Hartl, FU Hartl
Cell reports
(2019)
28
(doi: 10.1016/j.celrep.2019.06.081)
Promoting transparency and reproducibility in enhanced molecular simulations.
PLUMED consortium
Nature Methods
(2019)
16
(doi: 10.1038/s41592-019-0506-8)
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression
S De, DR Whiten, FS Ruggeri, C Hughes, M Rodrigues, DI Sideris, CG Taylor, FA Aprile, S Muyldermans, TPJ Knowles, M Vendruscolo, C Bryant, K Blennow, I Skoog, S Kern, H Zetterberg, D Klenerman
Acta Neuropathol Commun
(2019)
7
(doi: 10.1186/s40478-019-0777-4)
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly
K Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, T Knowles, SILVIA HERNANDEZ AINSA
(2019)
(doi: 10.26434/chemrxiv.8859017.v1)
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S HERNANDEZ AINSA
(2019)
(doi: 10.26434/chemrxiv.8859017)
Nature and Regulation of Protein Folding on the Ribosome
CA Waudby, CM Dobson, J Christodoulou
Trends in Biochemical Sciences
(2019)
44
(doi: 10.1016/j.tibs.2019.06.008)
The Toxicity of Misfolded Protein Oligomers Is Independent of Their Secondary Structure.
M Vivoli Vega, R Cascella, SW Chen, G Fusco, A De Simone, CM Dobson, C Cecchi, F Chiti
ACS Chemical Biology
(2019)
14
(doi: 10.1021/acschembio.9b00324)
Overexpression of osmosensitive Ca2+-activated channel TMEM63B promotes migration in HEK293T cells
M Marques, I Albuquerque, S Vaz, G Bernardes
Biochemistry
(2019)
(doi: 10.1101/626010)
Rapid two-dimensional characterisation of proteins insolution
KL Saar, Q Peter, T Müller, PK Challa, TW Herling, TPJ Knowles
Microsystems & Nanoengineering
(2019)
5
(doi: 10.1038/s41378-019-0072-3)
Universality of filamentous aggregation phenomena.
TCT Michaels, AJ Dear, TPJ Knowles
Physical Review E
(2019)
99
(doi: 10.1103/physreve.99.062415)
Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α-Synuclein and Polyglutamine in Aging Caenorhabditis elegans
RF Laine, T Sinnige, KY Ma, AJ Haack, C Poudel, P Gaida, N Curry, M Perni, EAA Nollen, CM Dobson, M Vendruscolo, GS Kaminski Schierle, CF Kaminski
ACS Chemical Biology
(2019)
14
(doi: 10.1021/acschembio.9b00354)
Analysis of αB-crystallin polydispersity in solution through native microfluidic electrophoresis
MA Wright, FS Ruggeri, KL Saar, PK Challa, JLP Benesch, TPJ Knowles
Analyst
(2019)
144
(doi: 10.1039/c9an00382g)
Overexpression of Osmosensitive Ca
MC Marques, IS Albuquerque, SH Vaz, GJL Bernardes
Biochemistry
(2019)
58
(doi: 10.1021/acs.biochem.9b00224)
Programmable On‐Chip Artificial Cell Producing Post‐Translationally Modified Ubiquitinated Protein
S Zilberzwige-Tal, A Levin, Z Toprakcioglu, TPJ Knowles, E Gazit, J Elbaz
Small
(2019)
15
(doi: 10.1002/smll.201901780)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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