Centre for Misfolding Diseases

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  • Currently displaying 721 - 740 of 2336 publications
Author(s)
Publication title
Journal Name
Publication year
Targeting the Formation of Amyloid Oligomers using Rationally Designed Antibodies
FA Aprile, P Sormanni, M Perni, P Arosio, S Linse, TP Knowles, CM Dobson, M Vendruscolo
Biophysical Journal
(2019)
116
(doi: 10.1016/j.bpj.2018.11.196)
Structure and Dynamics of Alzheimer's Associated Amyloid-Beta Peptide
T Lohr, K Kohlhoff, G Heller, M Vendruscolo
Biophysical Journal
(2019)
116
(doi: 10.1016/j.bpj.2018.11.2352)
In vitro and in silico assessment of the developability of a designed monoclonal antibody library.
A-M Wolf Pérez, P Sormanni, JS Andersen, LI Sakhnini, I Rodriguez-Leon, JR Bjelke, AJ Gajhede, L De Maria, DE Otzen, M Vendruscolo, N Lorenzen
Mabs
(2019)
11
(doi: 10.1080/19420862.2018.1556082)
Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation.
M Ahn, BI Lee, S Chia, J Habchi, JR Kumita, M Vendruscolo, CM Dobson, CB Park
Chem Commun (Camb)
(2019)
55
(doi: 10.1039/c8cc09288e)
De novo design of potent and selective mimics of IL-2/IL-15
D-A Silva, S Yu, UY Ulge, JB Spangler, KM Jude, C Labão-Almeida, LR Ali, A Quijano-Rubio, M Ruterbusch, I Leung, T Biary, SJ Crowley, E Marcos, CD Walkey, BD Weitzner, F Pardo-Avila, J Castellanos, L Carter, L Stewart, SR Riddell, M Pepper, GJL Bernardes, M Dougan, KC Garcia, D Baker
Nature
(2019)
565
(doi: 10.1038/s41586-018-0830-7)
Effects of α-tubulin acetylation on microtubule structure and stability
L Eshun-Wilson, R Zhang, D Portran, M Nachury, D Toso, T Lohr, M Vendruscolo, M Bonomi, J Fraser, E Nogales
(2019)
(doi: 10.1101/516591)
Physical determinants of amyloid assembly in biofilm formation
M Andreasen, G Meisl, JD Taylor, TCT Michaels, A Levin, DE Otzen, MR Chapman, CM Dobson, SJ Matthews, TPJ Knowles
mBio
(2019)
10
(doi: 10.1128/mbio.02279-18)
Nanostructured protein capsules
T Knowles
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
258
Analysis of αb-crystallin polydispersity in solution through native microfluidic electrophoresis
MA Wright, FS Ruggeri, KL Saar, PK Challa, JLP Benesch, TPJ Knowles
Analyst
(2019)
144
(doi: 10.1039/c9an00382g)
General sol to gel transition of liquid-liqud phase separated protein under shear
Y Shen, S Qamar, D Vigolo, A Kamada, S Zhang, P St George-Hyslop, T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2019)
48
Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent
MJ Matos, G Jiménez-Osés, GJL Bernardes
Methods Mol Biol
(2019)
2033
(doi: 10.1007/978-1-4939-9654-4_3)
Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation
JM Kirkpatrick, EK Sacramento, M Mazzetto, S Di Sanzo, C Caterino, A Bartolome, M Sanguanini, N Papaevgeniou, M Lefaki, D Childs, E Terzibasi-Tozzini, N Romanov, M Baumgart, W Huber, N Chondrogianni, M Vendruscolo, A Cellerino, A Ori
MOLECULAR & CELLULAR PROTEOMICS
(2019)
18
General sol to gel transition of liquid-liqud phase separated protein under shear
Y Shen, S Qamar, D Vigolo, A Kamada, S Zhang, P St George-Hyslop, T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2019)
48
Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ACB Burtoloso, G Jiménez-Osés, F Corzana, GJL Bernardes
Nat Protoc
(2019)
14
(doi: 10.1038/s41596-018-0083-9)
Proteome-wide analysis of protein stability in E. coli using pulse proteolysis
L Zhao, G Vecchi, M Vendruscolo, R Koerner, M Hayer-Hartl, U Hartl
MOLECULAR & CELLULAR PROTEOMICS
(2019)
18
Endogenous metabolites rescue a C. elegans model of Alzheimer's disease by triggering a heat shock response
P Joshi, M Perni, R Limbocker, B Mannini, S Casford, S Chia, J Labbadia, C Dobson, M Vendruscolo
FEBS OPEN BIO
(2019)
9
The presence of autoantibodies against the prion protein is independent of PRNP mutations
K Frontzek, M Carta, M Losa, M Epskamp, G Meisl, U Camenisch, T Knowles, S Hornemann, A Aguzzi
PRION
(2019)
13
Cytosolic aggregation of mitochondrial precursor proteins stimulates degeneration of cellular homeostasis
U Nowicka, P Chroscicki, K Stroobants, M Sladowska, M Turek, B Uszczynska-Ratajczak, R Kundra, T Goral, M Vendruscolo, A Chacinska
FEBS OPEN BIO
(2019)
9
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y-C Liao, M Fernandopulle, G Wang, H Choi, L Hao, CM Drerup, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, M Nelson, M Czekalska, G Musteikyte, R Patel, C Stephens, A Pasolli, L Forrest, PS George-Hyslop, J Lippincott-Schwartz, ME Ward
(2019)
(doi: 10.2139/ssrn.3312723)
In vitro and in silico Activity of Iridoids Against Leishmania amazonensis
MH Vendruscolo, GM das Neves, LP Kagami, LC Rodrigues Junior, ML Nunes Diehl, SCB Gnoatto, SA de Loreto Bordignon, PRT Romão, VL Eifler-Lima, GL von Poser
Curr Drug Discov Technol
(2019)
16
(doi: 10.2174/1570163814666171002102058)
Yusuf Hamied Department of Chemistry
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