Centre for Misfolding Diseases

Publications

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  • Currently displaying 641 - 660 of 2491 publications
Author(s)
Publication title
Journal Name
Publication year
Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response
P Joshi, M Perni, R Limbocker, B Mannini, S Casford, S Chia, J Habchi, J Labbadia, CM Dobson, M Vendruscolo
Communications biology
(2021)
4
(doi: 10.1038/s42003-021-02218-7)
Protein Conjugation by Electrophilic Alkynylation Using 5‑(Alkynyl)dibenzothiophenium Triflates
V Laserna, A Istrate, K Kafuta, TA Hakala, TPJ Knowles, M Alcarazo, GJL Bernardes
Bioconjugate chemistry
(2021)
32
(doi: 10.1021/acs.bioconjchem.1c00317)
Biomembranes in bioelectronic sensing.
AK Jayaram, AM Pappa, S Ghosh, ZA Manzer, WC Traberg, TPJ Knowles, S Daniel, RM Owens
Trends in Biotechnology
(2021)
40
(doi: 10.1016/j.tibtech.2021.06.001)
Soluble inflammatory Aβ-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease
DI Sideris, JSH Danial, D Emin, FS Ruggeri, Z Xia, YP Zhang, E Lobanova, H Dakin, S De, A Miller, JC Sang, TPJ Knowles, M Vendruscolo, G Fraser, D Crowther, D Klenerman
Brain Communications
(2021)
3
(doi: 10.1093/braincomms/fcab147)
Rational design of oligomer-specific antibodies as diagnostic tools for Alzheimer's and Parkinson's diseases
M Vendruscolo
FEBS OPEN BIO
(2021)
11
Microfluidic diffusional sizing for studying protein-protein interactions
MM Schneider, CM Dobson, A Aguzzi, FU Hartl, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2021)
50
Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy
F Brotzakis, T Lohr, M Vendruscolo
FEBS OPEN BIO
(2021)
11
Generic interactions in the condensed state of proteins
M Fuxreiter, M Vendruscolo
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2021)
50
Distinct responses of human peripheral blood cells to different misfolded protein oligomers.
M Leal-Lasarte, B Mannini, F Chiti, M Vendruscolo, CM Dobson, C Roodveldt, D Pozo
Immunology
(2021)
164
(doi: 10.1111/imm.13377)
Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers.
R Limbocker, R Staats, S Chia, FS Ruggeri, B Mannini, CK Xu, M Perni, R Cascella, A Bigi, LR Sasser, NR Block, AK Wright, RP Kreiser, ET Custy, G Meisl, S Errico, J Habchi, P Flagmeier, T Kartanas, JE Hollows, LT Nguyen, K LeForte, D Barbut, JR Kumita, C Cecchi, M Zasloff, TPJ Knowles, CM Dobson, F Chiti, M Vendruscolo
Frontiers in neuroscience
(2021)
15
(doi: 10.3389/fnins.2021.680026)
Machine learning-aided protein identification from multidimensional signatures
Y Zhang, MA Wright, KL Saar, P Challa, AS Morgunov, QAE Peter, S Devenish, CM Dobson, TPJ Knowles
Lab on A Chip
(2021)
21
(doi: 10.1039/d0lc01148g)
Controlled self-assembly of plant proteins into high-performance multifunctional nanostructured films
A Kamada, M Rodriguez-Garcia, FS Ruggeri, Y Shen, A Levin, TPJ Knowles
Nature Communications
(2021)
12
(doi: 10.1038/s41467-021-23813-6)
Generic nature of the condensed states of proteins
M Fuxreiter, M Vendruscolo
Nature Cell Biology
(2021)
23
(doi: 10.1038/s41556-021-00697-8)
Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy
ZF Brotzakis, T Löhr, M Vendruscolo
Chemical Science
(2021)
12
(doi: 10.1039/d1sc00244a)
pH‐Responsive Capsules with a Fibril Scaffold Shell Assembled from an Amyloidogenic Peptide
U Shimanovich, A Levin, D Eliaz, T Michaels, Z Toprakcioglu, B Frohm, E De Genst, S Linse, KS Åkerfeldt, TPJ Knowles
Small
(2021)
17
(doi: 10.1002/smll.202007188)
Deformable and robust core-shell protein microcapsules templated by liquid-liquid phase separated microdroplets
Y Xu, Y Shen, TCT Michaels, KN Baumann, D Vigolo, Q Peter, Y Lu, KL Saar, D Vella, H Zhu, B Li, H Yang, APM Guttenplan, M Rodriguez-Garcia, D Klenerman, TPJ Knowles
(2021)
(doi: 10.48550/arxiv.2009.13413)
Pulsed Hydrogen-Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer's Disease Mutants.
E Illes-Toth, G Meisl, DL Rempel, TPJ Knowles, ML Gross
ACS Chem Neurosci
(2021)
12
(doi: 10.1021/acschemneuro.1c00072)
In situ Sub-Cellular Identification of Functional Amyloids in Bacteria and Archaea by Infrared Nanospectroscopy.
DE Otzen, MS Dueholm, Z Najarzadeh, TPJ Knowles, FS Ruggeri
Small Methods
(2021)
5
(doi: 10.1002/smtd.202001002)
Rapid highly-sensitive general protein quantification through on-chip chemiluminescence
HK Chiu, T Kartanas, KL Saar, CM Luxhøj, S Devenish, TPJ Knowles
Biomicrofluidics
(2021)
15
(doi: 10.1063/5.0039872)
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
M Emmenegger, E De Cecco, M Hruska-Plochan, T Eninger, MM Schneider, M Barth, E Tantardini, P de Rossi, M Bacioglu, RG Langston, A Kaganovich, N Bengoa-Vergniory, A Gonzalez-Guerra, M Avar, D Heinzer, R Reimann, LM Häsler, TW Herling, NS Matharu, N Landeck, K Luk, R Melki, PJ Kahle, S Hornemann, TPJ Knowles, MR Cookson, M Polymenidou, M Jucker, A Aguzzi
(2021)
(doi: 10.1101/2021.04.25.441302)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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