Centre for Misfolding Diseases

Publications

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  • Currently displaying 641 - 660 of 2450 publications
Author(s)
Publication title
Journal Name
Publication year
A kinetic ensemble of the Alzheimer's Aβ peptide
T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo
Nature Computational Science
(2021)
1
(doi: 10.1038/s43588-020-00003-w)
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, S Sarwat, P Joshi, JR Kumita, S Linse, J Habchi, TPJ Knowles, B Mannini, CM Dobson, M Vendruscolo
Commun Biol
(2021)
4
(doi: 10.1038/s42003-020-01490-3)
Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies.
MC Hardenberg, T Sinnige, S Casford, ST Dada, C Poudel, EA Robinson, M Fuxreiter, CF Kaminksi, GS Kaminski Schierle, EAA Nollen, CM Dobson, M Vendruscolo
Journal of molecular cell biology
(2021)
13
(doi: 10.1093/jmcb/mjaa075)
Microfluidic diffusional sizing for studying protein-protein interactions
MM Schneider, CM Dobson, A Aguzzi, FU Hartl, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2021)
50
Generic interactions in the condensed state of proteins
M Fuxreiter, M Vendruscolo
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2021)
50
TRPV2 Modulation by Small Molecules and Lipids
AD Protopopova, RA Pumroy, J de la Roche, FM Haug, BB Sousa, PN Gallo, GJL Bernardes, A Leffler, VY Moiseenkova-Bell
BIOPHYSICAL JOURNAL
(2021)
120
DETECTION AND QUANTIFICATION OF IMMUNOLOGICALLY RELEVANT ALLOANTIBODY-HLA INTERACTIONS USING MICROFLUIDIC ANTIBODY AFFINITY PROFILING
A Priddey, M Schneider, G Karahan, T Scheidt, C Xu, G Meisl, H Copley, F Claas, R Buchli, A Mulder, S Heidt, T Knowles, V Kosmoliaptsis
TRANSPLANT INTERNATIONAL
(2021)
34
Therapeutics Against Protein Misfolded Oligomers in Neurodegenerative Diseases
R Limbocker, A Wright, RP Kreiser, B Mannini, M Vendruscolo
BIOPHYSICAL JOURNAL
(2021)
120
Rational design of oligomer-specific antibodies as diagnostic tools for Alzheimer's and Parkinson's diseases
M Vendruscolo
FEBS OPEN BIO
(2021)
11
Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy
F Brotzakis, T Lohr, M Vendruscolo
FEBS OPEN BIO
(2021)
11
A method of incorporating rate constants as kinetic constraints in molecular dynamics simulations.
ZF Brotzakis, M Vendruscolo, PG Bolhuis
Proceedings of the National Academy of Sciences
(2020)
118
(doi: 10.1073/pnas.2012423118)
Environmental Dependence of the Structure of the C-terminal Domain of the SARS-CoV-2 Envelope Protein
K Gadhave, A Kumar, P Kumar, SK Kapuganti, N Garg, M Vendruscolo, R Giri
(2020)
(doi: 10.1101/2020.12.29.424646)
Interactions of α-synuclein oligomers with lipid membranes.
G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, TPJ Knowles
Biochimica et Biophysica Acta (BBA) - Biomembranes
(2020)
1863
(doi: 10.1016/j.bbamem.2020.183536)
Environmental Control of Amyloid Polymorphism by Modulation of Hydrodynamic Stress
J Zhou, L Venturelli, L Keiser, SK Sekatskii, F Gallaire, S Kasas, G Longo, TPJ Knowles, FS Ruggeri, G Dietler
ACS Nano
(2020)
15
(doi: 10.1021/acsnano.0c07570)
In vitro measurements of protein–protein interactions show that antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in convalescent serum
S Fiedler, MA Piziorska, V Denninger, AS Morgunov, A Ilsley, AY Malik, MM Schneider, SRA Devenish, G Meisl, A Aguzzi, H Fiegler, TPJ Knowles
(2020)
(doi: 10.1101/2020.12.20.422820)
Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
F Geiger, G Papa, WE Arter, J Acker, KL Saar, N Erkamp, R Qi, J Bravo, S Strauss, G Krainer, OR Burrone, R Jungmann, TPJ Knowles, H Engelke, A Borodavka
(2020)
(doi: 10.1101/2020.12.18.423429)
Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameter.
R Staats, TCT Michaels, P Flagmeier, S Chia, RI Horne, J Habchi, S Linse, TPJ Knowles, CM Dobson, M Vendruscolo
Commun Chem
(2020)
3
(doi: 10.1038/s42004-020-00412-y)
Physical mechanisms of amyloid nucleation on fluid membranes.
J Krausser, TPJ Knowles, A Šarić
Proc Natl Acad Sci U S A
(2020)
117
(doi: 10.1073/PNAS.2007694117)
New solution for fast axial scanning in fluorescence microscopy
W Zong
Light Sci Appl
(2020)
9
(doi: 10.1038/s41377-020-00442-0)
Widespread occurrence of the droplet state of proteins in the human proteome.
M Hardenberg, A Horvath, V Ambrus, M Fuxreiter, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2020)
117
(doi: 10.1073/pnas.2007670117)
Yusuf Hamied Department of Chemistry
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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