Centre for Misfolding Diseases

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  • Currently displaying 581 - 600 of 2398 publications
Author(s)
Publication title
Journal Name
Publication year
Supramolecular Peptide Nanofibrils with Optimized Sequences and Molecular Structures for Efficient Retroviral Transduction
S Sieste, T Mack, E Lump, M Hayn, D Schütz, A Röcker, C Meier, F Kirchhoff, T Knowles, FS Ruggeri, C Synatschke, J Münch, T Weil
(2020)
(doi: 10.26434/chemrxiv.13129709.v1)
Rapid structural, kinetic, and immunochemical analysis of alpha-synuclein oligomers in solution
WE Arter, CK Xu, M Castellana-Cruz, TW Herling, G Krainer, KL Saar, JR Kumita, CM Dobson, TPJ Knowles
Nano Lett
(2020)
20
(doi: 10.1021/acs.nanolett.0c03260)
Microscale diffusiophoresis of proteins
Q Peter, R Jacquat, T Herling, P Challa, T Kartanas, T Knowles
(2020)
(doi: 10.21203/rs.3.rs-90645/v1)
An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase
AE Conicella, R Huang, ZA Ripstein, A Nguyen, E Wang, T Löhr, P Schuck, M Vendruscolo, JL Rubinstein, LE Kay
Proc Natl Acad Sci U S A
(2020)
117
(doi: 10.1073/pnas.2013920117)
Mechanistic insights into transition metal-mediated bioorthogonal uncaging reactions
E Latocheski, GM Dal Forno, TM Ferreira, BL Oliveira, GJL Bernardes, JB Domingos
Chemical Society Reviews
(2020)
49
(doi: 10.1039/d0cs00630k)
Serine-Selective Bioconjugation
JC Vantourout, SR Adusumalli, KW Knouse, DT Flood, A Ramirez, NM Padial, A Istrate, K Maziarz, JN deGruyter, RR Merchant, JX Qiao, MA Schmidt, MJ Deery, MD Eastgate, PE Dawson, GJL Bernardes, PS Baran
J Am Chem Soc
(2020)
142
(doi: 10.1021/jacs.0c05595)
The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils.
D Thacker, K Sanagavarapu, B Frohm, G Meisl, TPJ Knowles, S Linse
Proceedings of the National Academy of Sciences
(2020)
117
(doi: 10.1073/pnas.2002956117)
The role of clearance mechanisms in the kinetics of toxic protein aggregates involved in neurodegenerative diseases
TB Thompson, G Meisl, T Knowles, A Goriely
(2020)
(doi: 10.48550/arxiv.2009.14135)
Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies
S Linse, T Scheidt, K Bernfur, M Vendruscolo, CM Dobson, SIA Cohen, E Sileikis, M Lundqvist, F Qian, T O'Malley, T Bussiere, PH Weinreb, CK Xu, G Meisl, SRA Devenish, TPJ Knowles, O Hansson
Nature structural & molecular biology
(2020)
27
(doi: 10.1038/s41594-020-0505-6)
Deformable and robust core-shell protein microcapsules templated by liquid-liquid phase separated microdroplets
Y Xu, Y Shen, TCT Michaels, KN Baumann, D Vigolo, Q Peter, Y Lu, KL Saar, D Vella, H Zhu, B Li, H Yang, APM Guttenplan, M Rodriguez-Garcia, D Klenerman, TPJ Knowles
(2020)
(doi: 10.48550/arxiv.2009.13413)
Sequential dual site-selective protein labelling enabled by lysine modification.
MJ Matos, L Brown, B Bernardim, A Guerreiro, G Jiménez-Osés, GJL Bernardes
Bioorganic & medicinal chemistry
(2020)
28
(doi: 10.1016/j.bmc.2020.115783)
Microfluidic Affinity Profiling reveals a Broad Range of Target Affinities for Anti-SARS-CoV-2 Antibodies in Plasma of Covid Survivors
M Schneider, M Emmenegger, C Xu, IC Morales, G Meisl, P Turelli, C Zografou, M Zimmermann, B Frey, S Fiedler, V Denninger, R Jacquat, L Madrigal, A Ilsley, V Kosmoliaptsis, H Fiegler, D Trono, T Knowles, A Aguzzi
medRxiv
(2020)
(doi: 10.1101/2020.09.20.20196907)
Converting lateral scanning into axial focusing to speed up three-dimensional microscopy
T Chakraborty, B Chen, S Daetwyler, B-J Chang, O Vanderpoorten, E Sapoznik, CF Kaminski, TPJ Knowles, KM Dean, R Fiolka
Light, science & applications
(2020)
9
(doi: 10.1038/s41377-020-00401-9)
Converting lateral scanning into axial focusing to speed up three-dimensional microscopy.
T Chakraborty, B Chen, S Daetwyler, B-J Chang, O Vanderpoorten, E Sapoznik, CF Kaminski, TPJ Knowles, KM Dean, R Fiolka
Light Sci Appl
(2020)
9
(doi: 10.1038/s41377-020-00401-9)
A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer’s disease
T Ikenoue, FA Aprile, P Sormanni, FS Ruggeri, M Perni, GT Heller, CP Haas, C Middel, R Limbocker, B Mannini, TCT Michaels, TPJ Knowles, CM Dobson, M Vendruscolo
Scientific reports
(2020)
10
(doi: 10.1038/s41598-020-69626-3)
Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition
Y Shen, FS Ruggeri, D Vigolo, A Kamada, S Qamar, A Levin, C Iserman, S Alberti, PS George-Hyslop, TPJ Knowles
Nature Nanotechnology
(2020)
15
(doi: 10.1038/s41565-020-0731-4)
Biomimetic peptide self-assembly for functional materials
A Levin, TA Hakala, L Schnaider, GJL Bernardes, E Gazit, TPJ Knowles
Nat Rev Chem
(2020)
4
(doi: 10.1038/s41570-020-0215-y)
Microfluidic Antibody Affinity Profiling for In-Solution Characterisation of Alloantibody - HLA Interactions in Human Serum
M Schneider, T Scheidt, A Priddey, C Xu, M Hu, S Devenish, G Meisl, C Dobson, V Kosmoliaptsis, T Knowles
bioRxiv
(2020)
(doi: 10.1101/2020.09.14.296442)
Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors.
TCT Michaels, A Šarić, G Meisl, GT Heller, S Curk, P Arosio, S Linse, CM Dobson, M Vendruscolo, TPJ Knowles
Proceedings of the National Academy of Sciences
(2020)
117
(doi: 10.1073/pnas.2006684117)
Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors
JD Seixas, BB Sousa, MC Marques, A Guerreiro, R Traquete, T Rodrigues, IS Albuquerque, MFQ Sousa, AR Lemos, PMF Sousa, TM Bandeiras, D Wu, SK Doyle, CV Robinson, AN Koehler, F Corzana, PM Matias, GJL Bernardes
RSC Chemical Biology
(2020)
1
(doi: 10.1039/d0cb00033g)
Yusuf Hamied Department of Chemistry
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