Centre for Misfolding Diseases

Publications

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  • Currently displaying 581 - 600 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases
K Kulenkampff, A-M Wolf Perez, P Sormanni, J Habchi, M Vendruscolo
Nat Rev Chem
(2021)
5
(doi: 10.1038/s41570-021-00254-9)
Shear-Mediated Sol-Gel Transition of Regenerated Silk Allows the Formation of Janus-like Microgels
Z Toprakcioglu, T Knowles
(2021)
(doi: 10.26434/chemrxiv.13909250.v1)
Shear-Mediated Sol-Gel Transition of Regenerated Silk Allows the Formation of Janus-like Microgels
Z Toprakcioglu, T Knowles
(2021)
(doi: 10.26434/chemrxiv.13909250)
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition
WK Man, B Tahirbegi, MD Vrettas, S Preet, L Ying, M Vendruscolo, A De Simone, G Fusco
Nat Commun
(2021)
12
(doi: 10.1038/s41467-021-21027-4)
Aβ Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors
G Fani, B Mannini, G Vecchi, R Cascella, C Cecchi, CM Dobson, M Vendruscolo, F Chiti
ACS Chem Neurosci
(2021)
12
(doi: 10.1021/acschemneuro.0c00811)
One-Step Generation of Multisomes from Lipid-Stabilized Double Emulsions
MA Czekalska, AMJ Jacobs, Z Toprakcioglu, L Kong, KN Baumann, H Gang, G Zubaite, R Ye, B Mu, A Levin, WTS Huck, TPJ Knowles
ACS Appl Mater Interfaces
(2021)
13
(doi: 10.1021/acsami.0c16019)
Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions
G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.426)
Direct Digital Sensing of Proteins in Solution through Single-Molecule Optofluidics
G Krainer, KL Saar, WE Arter, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.2269)
Infrared Nanospectroscopy Reveals the Molecular Interaction Fingerprint of an Aggregation Inhibitor with Single Ab42 Oligomers
FS Ruggeri, J Habchi, S Chia, RI Horne, M Vendruscolo, TPJ Knowles
Nat Commun
(2021)
12
(doi: 10.1038/s41467-020-20782-0)
Label-Free Protein Analysis Using Liquid Chromatography with Gravimetric Detection.
T Kartanas, A Levin, Z Toprakcioglu, T Scheidt, TA Hakala, J Charmet, TPJ Knowles
Analytical chemistry
(2021)
93
(doi: 10.1021/acs.analchem.0c04149)
In situ kinetic measurements of α-synuclein aggregation reveal large population of short-lived oligomers
E Zurlo, P Kumar, G Meisl, AJ Dear, D Mondal, MMAE Claessens, TPJ Knowles, M Huber
PLoS One
(2021)
16
(doi: 10.1371/journal.pone.0245548)
Facile Installation of Post-translational Modifications on the Tau Protein via Chemical Mutagenesis
PR Lindstedt, RJ Taylor, GJL Bernardes, M Vendruscolo
ACS Chemical Neuroscience
(2021)
12
(doi: 10.1021/acschemneuro.0c00761)
A kinetic ensemble of the Alzheimer's Aβ peptide
T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo
Nat Comput Sci
(2021)
1
(doi: 10.1038/s43588-020-00003-w)
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, S Sarwat, P Joshi, JR Kumita, S Linse, J Habchi, TPJ Knowles, B Mannini, CM Dobson, M Vendruscolo
Communications Biology
(2021)
4
(doi: 10.1038/s42003-020-01490-3)
Observation of an α-1synuclein liquid droplet state and its maturation into Lewy body-like assemblies
MC Hardenberg, T Sinnige, S Casford, ST Dada, C Poudel, EA Robinson, M Fuxreiter, CF Kaminksi, GS Kaminski Schierle, EAA Nollen, CM Dobson, M Vendruscolo
Journal of Molecular Cell Biology
(2021)
13
(doi: 10.1093/jmcb/mjaa075)
DETECTION AND QUANTIFICATION OF IMMUNOLOGICALLY RELEVANT ALLOANTIBODY-HLA INTERACTIONS USING MICROFLUIDIC ANTIBODY AFFINITY PROFILING
A Priddey, M Schneider, G Karahan, T Scheidt, C Xu, G Meisl, H Copley, F Claas, R Buchli, A Mulder, S Heidt, T Knowles, V Kosmoliaptsis
TRANSPLANT INTERNATIONAL
(2021)
34
Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy
F Brotzakis, T Lohr, M Vendruscolo
FEBS OPEN BIO
(2021)
11
Rational design of oligomer-specific antibodies as diagnostic tools for Alzheimer's and Parkinson's diseases
M Vendruscolo
FEBS OPEN BIO
(2021)
11
Generic interactions in the condensed state of proteins
M Fuxreiter, M Vendruscolo
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2021)
50
TRPV2 Modulation by Small Molecules and Lipids
AD Protopopova, RA Pumroy, J de la Roche, FM Haug, BB Sousa, PN Gallo, GJL Bernardes, A Leffler, VY Moiseenkova-Bell
BIOPHYSICAL JOURNAL
(2021)
120
Yusuf Hamied Department of Chemistry
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