Centre for Misfolding Diseases

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  • Currently displaying 581 - 600 of 2517 publications
Author(s)
Publication title
Journal Name
Publication year
Retaining the structural integrity of disulfide bonds in diphtheria toxoid carrier protein is crucial for the effectiveness of glycoconjugate vaccine candidates.
F Carboni, A Kitowski, C Sorieul, D Veggi, MC Marques, D Oldrini, E Balducci, B Brogioni, L Del Bino, A Corrado, F Angiolini, L Dello Iacono, I Margarit, MR Romano, GJL Bernardes, R Adamo
Chem Sci
(2022)
13
(doi: 10.1039/d1sc01928g)
Multiphase condensates from a kinetically arrested phase transition
NA Erkamp, T Sneideris, H Ausserwöger, D Qian, S Qamar, J Nixon-Abell, P St George-Hyslop, JD Schmit, DA Weitz, TPJ Knowles
(2022)
(doi: 10.1101/2022.02.09.479538)
Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration
S Fiedler, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, M Emmenegger, V Kosmoliaptsis, ES Theel, JR Mills, AM Sholukh, A Aguzzi, A Iwasaki, AK Lynn, TPJ Knowles
(2022)
(doi: 10.1101/2022.02.03.478946)
Nanofluidic Traps by Two-Photon Fabrication for Extended Detection of Single Macromolecules and Colloids in Solution
O Vanderpoorten, AN Babar, G Krainer, RPB Jacquat, PK Challa, Q Peter, Z Toprakcioglu, CK Xu, UF Keyser, JJ Baumberg, CF Kaminski, TPJ Knowles
ACS Applied Nano Materials
(2022)
5
(doi: 10.1021/acsanm.1c03691)
Phase separating RNA binding proteins form heterogeneous distributions of clusters in subsaturated solutions
M Kar, F Dar, TJ Welsh, L Vogel, R Kühnemuth, A Majumdar, G Krainer, TM Franzmann, S Alberti, CAM Seidel, TPJ Knowles, AA Hyman, RV Pappu
(2022)
(doi: 10.1101/2022.02.03.478969)
Rate‐limiting processes of tau aggregate accumulation in Alzheimer's disease
G Meisl, Y Zuo, K Allinson, T Rittman, SL DeVos, JS Sanchez, CK Xu, KE Duff, KA Johnson, JB Rowe, BT Hyman, T Knowles, D Klenerman
Alzheimer's & Dementia
(2022)
17
(doi: 10.1002/alz.051680)
Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics.
R Khetan, R Curtis, CM Deane, JT Hadsund, U Kar, K Krawczyk, D Kuroda, SA Robinson, P Sormanni, K Tsumoto, J Warwicker, ACR Martin
Mabs
(2022)
14
(doi: 10.1080/19420862.2021.2020082)
Transition metal mediated bioorthogonal release
V Sabatino, VB Unnikrishnan, GJL Bernardes
Chem Catalysis
(2022)
2
(doi: 10.1016/j.checat.2021.12.007)
A Machine Learning Approach to Identify Small Molecule Inhibitors of Secondary Nucleation in α-Synuclein Aggregation
R Horne, A Possenti, S Chia, ZF Brotzakis, R Staats, M Nowinska, M Vendruscolo
(2022)
(doi: 10.21203/rs.3.rs-1236129/v1)
DNA-Liposome Hybrid Carriers for Triggered Cargo Release
KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa
(2022)
(doi: 10.26434/chemrxiv-2022-x731g)
DNA-Liposome Hybrid Carriers for TriggeredCargo Release
KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa
(2022)
(doi: 10.26434/chemrxiv-2022-x731g-v2)
Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates.
TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
Nano letters
(2022)
22
(doi: 10.1021/acs.nanolett.1c03138)
Controlled In‐Cell Generation of Active Palladium(0) Species for Bioorthogonal Decaging
J Konč, V Sabatino, E Jiménez‐Moreno, E Latocheski, LR Pérez, J Day, JB Domingos, GJL Bernardes
Angewandte Chemie
(2022)
134
(doi: 10.1002/ange.202113519)
Droplet Dynamics in Asymmetric Microfluidic Junctions
H Yang, Y Xu, T Knowles
(2022)
(doi: 10.2139/ssrn.4159999)
Improving safety in regional anaesthesia with a novel, yet simple intervention. A staff survey of the impact of the intervention
R Thomas, S Jigajinni, S Green, T Knowles, R McCartney, A Williams
ANAESTHESIA
(2022)
77
Sequence-Based Prediction of Ph-Dependent Protein Solubility Using Camsol
M Oeller, R Kang, R Bell, H Ausserwoger, P Sormanni, M Vendruscolo
SSRN Electronic Journal
(2022)
(doi: 10.2139/ssrn.4189397)
Microchip Free-Flow Electrophoresis for Bioanalysis, Sensing, and Purification
WE Arter, KL Saar, TW Herling, TPJ Knowles
(2022)
2394
(doi: 10.1007/978-1-0716-1811-0_16)
Common sequence motifs of nascent chains engage the ribosome surface and trigger factor.
A Deckert, AME Cassaignau, X Wang, T Włodarski, SHS Chan, CA Waudby, JP Kirkpatrick, M Vendruscolo, LD Cabrita, J Christodoulou
Proc Natl Acad Sci U S A
(2021)
118
(doi: 10.1073/pnas.2103015118)
Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer’s Disease
M Runfola, M Perni, X Yang, M Marchese, A Bacci, S Mero, FM Santorelli, B Polini, G Chiellini, D Giuliani, A Vilella, M Bodria, E Daini, E Vandini, S Rudge, S Gul, MOJ Wakelam, M Vendruscolo, S Rapposelli
Pharmaceuticals
(2021)
14
(doi: 10.3390/ph14121330)
Single-molecule sizing through nano-cavity confinement
RPB Jacquat, G Krainer, QAE Peter, AN Babar, O Vanderpoorten, CK Xu, TJ Welsh, CF Kaminski, UF Keyser, JJ Baumberg, TPJ Knowles
(2021)
(doi: 10.1101/2021.12.13.472369)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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