Centre for Misfolding Diseases

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  • Currently displaying 681 - 700 of 2336 publications
Author(s)
Publication title
Journal Name
Publication year
Determination of protein structural ensembles using cryo-electron microscopy.
M Bonomi, M Vendruscolo
Curr Opin Struct Biol
(2019)
56
(doi: 10.1016/j.sbi.2018.10.006)
Expression of the amyloid-β peptide in a single pair of C. elegans sensory neurons modulates the associated behavioural response
T Sinnige, P Ciryam, S Casford, CM Dobson, M de Bono, M Vendruscolo
PloS one
(2019)
14
(doi: 10.1371/journal.pone.0217746)
Defining α-synuclein species responsible for Parkinson disease phenotypes in mice
JM Froula, M Castellana-Cruz, NM Anabtawi, JD Camino, SW Chen, DR Thrasher, J Freire, AA Yazdi, S Fleming, CM Dobson, JR Kumita, N Cremades, LA Volpicelli-Daley
Journal of Biological Chemistry
(2019)
294
(doi: 10.1074/jbc.ra119.007743)
Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation.
C Torrini, RJ Cubero, E Dirkx, L Braga, H Ali, G Prosdocimo, MI Gutierrez, C Collesi, D Licastro, L Zentilin, M Mano, S Zacchigna, M Vendruscolo, M Marsili, A Samal, M Giacca
Cell reports
(2019)
27
(doi: 10.1016/j.celrep.2019.05.005)
A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data.
AK Sharma, P Sormanni, N Ahmed, P Ciryam, UA Friedrich, G Kramer, EP O'Brien
Plos Computational Biology
(2019)
15
(doi: 10.1371/journal.pcbi.1007070)
Development of a self-immolative linker for tetrazine-triggered release of alcohols in cells
S Davies, B Oliveira, GJL Bernardes
Org Biomol Chem
(2019)
17
(doi: 10.1039/c9ob01167f)
Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies
R Cascella, M Perni, SW Chen, G Fusco, C Cecchi, M Vendruscolo, F Chiti, CM Dobson, A De Simone
ACS chemical biology
(2019)
14
(doi: 10.1021/acschembio.9b00312)
Effects of α-tubulin acetylation on microtubule structure and stability.
L Eshun-Wilson, R Zhang, D Portran, MV Nachury, DB Toso, T Löhr, M Vendruscolo, M Bonomi, JS Fraser, E Nogales
Proc Natl Acad Sci U S A
(2019)
116
(doi: 10.1073/pnas.1900441116)
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation.
MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, B Bernardim, KL Saar, I Compañón, F Corzana, TPJ Knowles, G Jiménez-Osés, GJL Bernardes
Angewandte Chemie International Edition
(2019)
58
(doi: 10.1002/anie.201901405)
Dissecting celastrol with machine learning to unveil dark pharmacology.
T Rodrigues, BP de Almeida, NL Barbosa-Morais, GJL Bernardes
Chem Commun (Camb)
(2019)
55
(doi: 10.1039/c9cc03116b)
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in caenorhabditis elegans
C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, T Sinnige, MC Lechler, N Schlörit, M Lu, RF Laine, CH Michel, M Vendruscolo, CF Kaminski, GS Kaminski Schierle, DC David
Elife
(2019)
8
(doi: 10.7554/elife.43059)
Computational advances in combating colloidal aggregation in drug discovery.
D Reker, GJL Bernardes, T Rodrigues
Nat Chem
(2019)
11
(doi: 10.1038/s41557-019-0234-9)
Potassium Arylethynyltrifluoroborate as an Unstrained Dienophile for Ultrafast and On Demand Activation of Bioorthogonal IEDDA Reactions
Z Guo, B Oliveira, C Navo, P M. S. D. Cal, F Corzana, G Jiménez-Osés, G Bernardes
(2019)
(doi: 10.26434/chemrxiv.8038685.v1)
Determination of the structural ensemble of the molten globule state of a protein by computer simulations.
M Shimizu, Y Kajikawa, K Kuwajima, CM Dobson, Y Okamoto
Proteins: Structure, Function, and Bioinformatics
(2019)
87
(doi: 10.1002/prot.25688)
Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming.
N Ahmed, P Sormanni, P Ciryam, M Vendruscolo, CM Dobson, EP O'Brien
Sci Rep
(2019)
9
(doi: 10.1038/s41598-019-42348-x)
Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates
T Scheidt, U Łapińska, JR Kumita, DR Whiten, D Klenerman, MR Wilson, SIA Cohen, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles, P Arosio
Science Advances
(2019)
5
(doi: 10.1126/sciadv.aau3112)
Sequence-Optimized Peptide Nanofibers as Growth Stimulators for Regeneration of Peripheral Neurons
C Schilling, T Mack, S Lickfett, S Sieste, FS Ruggeri, T Sneideris, A Dutta, T Bereau, R Naraghi, D Sinske, TPJ Knowles, CV Synatschke, T Weil, B Knöll
Advanced Functional Materials
(2019)
29
(doi: 10.1002/adfm.201809112)
Biophysical Techniques in Structural Biology.
CM Dobson
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 88
(2019)
88
(doi: 10.1146/annurev-biochem-013118-111947)
The free energy landscape of the oncogene protein E7 of human papillomavirus type 16 reveals a complex interplay between ordered and disordered regions
P Kukic, GM Lo Piccolo, MO Nogueira, DI Svergun, M Vendruscolo, IC Felli, R Pierattelli
Scientific reports
(2019)
9
(doi: 10.1038/s41598-019-41925-4)
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation
MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, B Bernardim, KL Saar, I Compañón, F Corzana, TPJ Knowles, G Jiménez‐Osés, GJL Bernardes
Angewandte Chemie
(2019)
131
(doi: 10.1002/ange.201901405)
Yusuf Hamied Department of Chemistry
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