Centre for Misfolding Diseases

Publications

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  • Currently displaying 681 - 700 of 2398 publications
Author(s)
Publication title
Journal Name
Publication year
A microfluidic strategy for the detection of membrane protein interactions.
Y Zhang, TW Herling, S Kreida, QAE Peter, T Kartanas, S Törnroth-Horsefield, S Linse, TPJ Knowles
Lab on a chip
(2020)
20
(doi: 10.1039/d0lc00205d)
Making biological membrane resistant to the toxicity of misfolded protein oligomers: A lesson from trodusquemine
S Errico, G Lucchesi, D Odino, S Muscat, C Capitini, C Bugelli, C Canale, R Ferrando, G Grasso, D Barbut, M Calamai, A Danani, M Zasloff, A Relini, G Caminati, M Vendruscolo, F Chiti
Nanoscale
(2020)
12
(doi: 10.1039/d0nr05285j)
Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions (vol 31, pg 125, 2020)
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GJL Bernandes, TPJ Knowles
Soft matter
(2020)
16
(doi: 10.1039/d0sm90059a)
Investigation of Natural and Synthetic Aggregation Inhibitors using Microfluidic Applications
T Scheidt, J Carozza, JL Benesch, P Arosio, S Linse, TPJ Knowles
BIOPHYSICAL JOURNAL
(2020)
118
Local micro and nano patterning of microfluidic devices using the solid on liquid deposition process
J Charmet, A Homsy, M Wood, J Covington, L Isa, M Textor, TPJ Knowles, H Keppner
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences Microtas 2017
(2020)
Rational Design of Conformation-Specific Antibodies for Tau Oligomers
K Kulenkampff, FA Aprile, P Sormanni, RT Ranasinghe, D Klenerman, M Vendruscolo
BIOPHYSICAL JOURNAL
(2020)
118
Polyglutamine Aggregation in a Living Animal is Governed by Biophysical Parameters
T Sinnige, T Michaels, M Vendruscolo, RI Morimoto
BIOPHYSICAL JOURNAL
(2020)
118
Proteome-wide observation of the phenomenon of life on the edge of solubility.
G Vecchi, P Sormanni, B Mannini, A Vandelli, GG Tartaglia, CM Dobson, FU Hartl, M Vendruscolo
Proc Natl Acad Sci U S A
(2019)
117
(doi: 10.1073/pnas.1910444117)
Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains
M Maritan, M Romeo, L Oberti, P Sormanni, M Tasaki, R Russo, A Ambrosetti, P Motta, P Rognoni, G Mazzini, A Barbiroli, G Palladini, M Vendruscolo, L Diomede, M Bolognesi, G Merlini, F Lavatelli, S Ricagno
Journal of Molecular Biology
(2019)
432
(doi: 10.1016/j.jmb.2019.12.015)
Determination of a Structural Ensemble Representing the Dynamics of a G-Quadruplex DNA.
G Portella, M Orozco, M Vendruscolo
Biochemistry
(2019)
59
(doi: 10.1021/acs.biochem.9b00493)
Homage to Chris Dobson
J Baum, F Chiti, A De Simone, TPJ Knowles, JR Kumita, SE Radford, CV Robinson, X Salvatella, K Valelli, M Vendruscolo, A Pastore, GG Tartaglia
Front Mol Biosci
(2019)
6
(doi: 10.3389/fmolb.2019.00137)
Proteome-Wide Survey of Cysteine Oxidation by Using a Norbornene Probe.
LJ Alcock, M Langini, K Stühler, M Remke, MV Perkins, GJL Bernardes, JM Chalker
Chembiochem : a European journal of chemical biology
(2019)
21
(doi: 10.1002/cbic.201900729)
A metastable subproteome underlies inclusion formation in muscle proteinopathies.
P Ciryam, M Antalek, F Cid, GG Tartaglia, CM Dobson, A-K Guettsches, B Eggers, M Vorgerd, K Marcus, RA Kley, RI Morimoto, M Vendruscolo, CC Weihl
Acta Neuropathol Commun
(2019)
7
(doi: 10.1186/s40478-019-0853-9)
Protein solubility predictions using the camsol method in the study of protein homeostasis
P Sormanni, M Vendruscolo
Cold Spring Harb Perspect Biol
(2019)
11
(doi: 10.1101/cshperspect.a033845)
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes.
R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, B Mannini, J Habchi, TCT Michaels, PK Challa, M Ahn, ST Casford, N Fernando, CK Xu, ND Kloss, SIA Cohen, JR Kumita, C Cecchi, M Zasloff, S Linse, TPJ Knowles, F Chiti, M Vendruscolo, CM Dobson
Nature Communications
(2019)
10
(doi: 10.1038/s41467-018-07699-5)
Label-Free Analysis of Protein Aggregation and Phase Behavior.
Z Toprakcioglu, P Challa, C Xu, TPJ Knowles
ACS Nano
(2019)
13
(doi: 10.1021/acsnano.9b05552)
Supersaturated proteins are enriched at synapses and underlie cell and tissue vulnerability in Alzheimer's disease.
R Freer, P Sormanni, P Ciryam, B Rammner, SO Rizzoli, CM Dobson, M Vendruscolo
Heliyon
(2019)
5
(doi: 10.1016/j.heliyon.2019.e02589)
Machine learning for target discovery in drug development.
T Rodrigues, GJL Bernardes
Current opinion in chemical biology
(2019)
56
(doi: 10.1016/j.cbpa.2019.10.003)
Protein Microgels from Amyloid Fibril Networks.
LWY Roode, U Shimanovich, S Wu, S Perrett, TPJ Knowles
Adv Exp Med Biol
(2019)
1174
(doi: 10.1007/978-981-13-9791-2_7)
Dynamics and Control of Peptide Self-Assembly and Aggregation
G Meisl, TCT Michaels, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Advances in experimental medicine and biology
(2019)
1174
(doi: 10.1007/978-981-13-9791-2_1)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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