Centre for Misfolding Diseases

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  • Currently displaying 681 - 700 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Microfluidic Templating of Spatially Inhomogeneous Protein Microgels
Y Xu, RPB Jacquat, Y Shen, D Vigolo, D Morse, S Zhang, TPJ Knowles
Small (Weinheim an der Bergstrasse, Germany)
(2020)
16
(doi: 10.1002/smll.202000432)
Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy
FS Ruggeri, B Mannini, R Schmid, M Vendruscolo, TPJ Knowles
Nat Commun
(2020)
11
(doi: 10.1038/s41467-020-16728-1)
Identification of on- and off-pathway oligomers in amyloid fibril formation.
AJ Dear, G Meisl, A Šarić, TCT Michaels, M Kjaergaard, S Linse, TPJ Knowles
Chem Sci
(2020)
11
(doi: 10.1039/c9sc06501f)
High Resolution Biomolecular Condensate Phase Diagrams with a Combinatorial Microdroplet Platform
WE Arter, R Qi, NA Erkamp, G Krainer, K Didi, TJ Welsh, J Acker, J Nixon-Abell, S Qamar, J Guillén-Boixet, TM Franzmann, D Kuster, AA Hyman, A Borodavka, P St George-Hyslop, S Alberti, TPJ Knowles
(2020)
(doi: 10.1101/2020.06.04.132308)
Lipid membranes from naked mole-rat brain lipids are cholesterol-rich, highly phase-separated, and sensitive to amyloid-induced damage
D Frankel, M Davies, B Bhushan, Y Kulaberoglu, P Urriola-Munoz, J Bertrand-Michel, MR Pergande, AA Smith, S Preet, TJ Park, M Vendruscolo, K Rankin, SM Cologna, JR Kumita, N Cenac, E St John Smith
(2020)
(doi: 10.1101/2020.06.05.134973)
Biophysical studies of protein misfolding and aggregation in in vivo models of Alzheimer's and Parkinson's diseases.
T Sinnige, K Stroobants, CM Dobson, M Vendruscolo
Quarterly reviews of biophysics
(2020)
53
(doi: 10.1017/S0033583520000025)
Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large metropolitan region
M Emmenegger, E De Cecco, D Lamparter, RPB Jacquat, J Riou, D Menges, T Ballouz, D Ebner, MM Schneider, IC Morales, B Doğançay, J Guo, A Wiedmer, J Domange, M Imeri, R Moos, C Zografou, L Batkitar, L Madrigal, D Schneider, C Trevisan, A Gonzalez-Guerra, A Carrella, IL Dubach, CK Xu, G Meisl, V Kosmoliaptsis, T Malinauskas, N Burgess-Brown, R Owens, S Hatch, J Mongkolsapaya, GR Screaton, K Schubert, JD Huck, F Liu, F Pojer, K Lau, D Hacker, E Probst-Müller, C Cervia, J Nilsson, O Boyman, L Saleh, K Spanaus, A von Eckardstein, DJ Schaer, N Ban, C-J Tsai, J Marino, GFX Schertler, N Ebert, V Thiel, J Gottschalk, BM Frey, R Reimann, S Hornemann, AM Ring, TPJ Knowles, MA Puhan, CL Althaus, I Xenarios, DI Stuart, A Aguzzi
(2020)
(doi: 10.1101/2020.05.31.20118554)
Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors.
K McAulay, EA Hoyt, M Thomas, M Schimpl, MS Bodnarchuk, HJ Lewis, D Barratt, D Bhavsar, DM Robinson, MJ Deery, DJ Ogg, GJL Bernardes, RA Ward, MJ Waring, JG Kettle
J Am Chem Soc
(2020)
142
(doi: 10.1021/jacs.9b13391)
Synthesis, characterization and photoinduced CO-release by manganese(i) complexes
AL Amorim, A Guerreiro, VA Glitz, DF Coimbra, AJ Bortoluzzi, GF Caramori, AL Braga, A Neves, GJL Bernardes, RA Peralta
New Journal of Chemistry
(2020)
44
(doi: 10.1039/d0nj02260h)
Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses
J Pansieri, IA Iashchishyn, H Fakhouri, L Ostojić, M Malisauskas, G Musteikyte, V Smirnovas, MM Schneider, T Scheidt, CK Xu, G Meisl, TPJ Knowles, E Gazit, R Antoine, LA Morozova-Roche
(2020)
(doi: 10.1101/2020.05.26.116400)
Direct digital sensing of protein biomarkers in solution
G Krainer, KL Saar, WE Arter, TJ Welsh, MA Czekalska, RPB Jacquat, Q Peter, WC Traberg, A Pujari, AK Jayaram, P Challa, CG Taylor, L-M van der Linden, T Franzmann, RM Owens, S Alberti, D Klenerman, TPJ Knowles
BIOPHYSICAL JOURNAL
(2020)
120
(doi: 10.1101/2020.05.24.113498)
Digital Sensing and Molecular Computation by an Enzyme-Free DNA Circuit.
WE Arter, Y Yusim, Q Peter, CG Taylor, D Klenerman, UF Keyser, TPJ Knowles
ACS Nano
(2020)
14
(doi: 10.1021/acsnano.0c00628)
Platinum-Triggered Bond-Cleavage of Pentynoyl Amide and N-Propargyl Handles for Drug-Activation
BL Oliveira, BJ Stenton, VB Unnikrishnan, CR de Almeida, J Conde, M Negrão, FSS Schneider, C Cordeiro, MG Ferreira, GF Caramori, JB Domingos, R Fior, GJL Bernardes
Journal of the American Chemical Society
(2020)
142
(doi: 10.1021/jacs.0c01622)
Sequence-based prediction of protein binding mode landscapes.
A Horvath, M Miskei, V Ambrus, M Vendruscolo, M Fuxreiter
PLoS computational biology
(2020)
16
(doi: 10.1371/journal.pcbi.1007864)
Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils
M Törnquist, R Cukalevski, U Weininger, G Meisl, TPJ Knowles, T Leiding, A Malmendal, M Akke, S Linse
Proceedings of the National Academy of Sciences
(2020)
117
(doi: 10.1073/pnas.1918481117)
Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform.
M Koopman, Q Peter, RI Seinstra, M Perni, M Vendruscolo, CM Dobson, TPJ Knowles, EAA Nollen
Nature protocols
(2020)
15
(doi: 10.1038/s41596-020-0321-9)
Kinetic diversity of amyloid oligomers.
AJ Dear, TCT Michaels, G Meisl, D Klenerman, S Wu, S Perrett, S Linse, CM Dobson, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2020)
117
(doi: 10.1073/pnas.1922267117)
A Sweet Galactose Transfer: Metabolic Oligosaccharide Engineering as a Tool To Study Glycans in Plasmodium Infection
A Kitowski, GJL Bernardes
Chembiochem : a European journal of chemical biology
(2020)
21
(doi: 10.1002/cbic.202000226)
Brain-Sparing Sympathofacilitators Mitigate Obesity without Adverse Cardiovascular Effects
I Mahú, A Barateiro, E Rial-Pensado, N Martinéz-Sánchez, SH Vaz, PMSD Cal, B Jenkins, T Rodrigues, C Cordeiro, MF Costa, R Mendes, E Seixas, MMA Pereira, N Kubasova, V Gres, I Morris, C Temporão, M Olivares, Y Sanz, A Koulman, F Corzana, AM Sebastião, M López, GJL Bernardes, AI Domingos
Cell Metab
(2020)
31
(doi: 10.1016/j.cmet.2020.04.013)
The antidiabetic drug lobeglitazone has the potential to inhibit PTP1B activity
RF Rocha, T Rodrigues, ACO Menegatti, GJL Bernardes, H Terenzi
Bioorg Chem
(2020)
100
(doi: 10.1016/j.bioorg.2020.103927)
Yusuf Hamied Department of Chemistry
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