Centre for Misfolding Diseases

Publications

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  • Currently displaying 741 - 760 of 2396 publications
Author(s)
Publication title
Journal Name
Publication year
Making biological membrane resistant to the toxicity of misfolded protein oligomers: a lesson from trodusquemine.
S Errico, G Lucchesi, D Odino, S Muscat, C Capitini, C Bugelli, C Canale, R Ferrando, G Grasso, D Barbut, M Calamai, A Danani, M Zasloff, A Relini, G Caminati, M Vendruscolo, F Chiti
Nanoscale
(2020)
12
(doi: 10.1039/d0nr05285j)
Local micro and nano patterning of microfluidic devices using the solid on liquid deposition process
J Charmet, A Homsy, M Wood, J Covington, L Isa, M Textor, TPJ Knowles, H Keppner
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences Microtas 2017
(2020)
Proteome-wide observation of the phenomenon of life on the edge of solubility
G Vecchi, P Sormanni, B Mannini, A Vandelli, GG Tartaglia, CM Dobson, FU Hartl, M Vendruscolo
Proceedings of the National Academy of Sciences
(2019)
117
(doi: 10.1073/pnas.1910444117)
Physical mechanisms of amyloid nucleation on fluid membranes
J Krausser, TPJ Knowles, A Šarić
(2019)
(doi: 10.1101/2019.12.22.886267)
Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains.
M Maritan, M Romeo, L Oberti, P Sormanni, M Tasaki, R Russo, A Ambrosetti, P Motta, P Rognoni, G Mazzini, A Barbiroli, G Palladini, M Vendruscolo, L Diomede, M Bolognesi, G Merlini, F Lavatelli, S Ricagno
Journal of Molecular Biology
(2019)
432
(doi: 10.1016/j.jmb.2019.12.015)
Homage to Chris Dobson
J Baum, F Chiti, A De Simone, TPJ Knowles, JR Kumita, SE Radford, CV Robinson, X Salvatella, K Valelli, M Vendruscolo, A Pastore, GG Tartaglia
Front Mol Biosci
(2019)
6
(doi: 10.3389/fmolb.2019.00137)
Determination of a Structural Ensemble Representing the Dynamics of a G-Quadruplex DNA.
G Portella, M Orozco, M Vendruscolo
Biochemistry
(2019)
59
(doi: 10.1021/acs.biochem.9b00493)
Proteome‐Wide Survey of Cysteine Oxidation by Using a Norbornene Probe
LJ Alcock, M Langini, K Stühler, M Remke, MV Perkins, GJL Bernardes, JM Chalker
Chembiochem
(2019)
21
(doi: 10.1002/cbic.201900729)
A metastable subproteome underlies inclusion formation in muscle proteinopathies
P Ciryam, M Antalek, F Cid, GG Tartaglia, CM Dobson, A-K Guettsches, B Eggers, M Vorgerd, K Marcus, RA Kley, RI Morimoto, M Vendruscolo, CC Weihl
Acta Neuropathol Commun
(2019)
7
(doi: 10.1186/s40478-019-0853-9)
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, B Mannini, J Habchi, TCT Michaels, PK Challa, M Ahn, ST Casford, N Fernando, CK Xu, ND Kloss, SIA Cohen, JR Kumita, C Cecchi, M Zasloff, S Linse, TPJ Knowles, F Chiti, M Vendruscolo, CM Dobson
Nature Communications
(2019)
10
(doi: 10.1038/s41467-018-07699-5)
Supersaturated proteins are enriched at synapses and underlie cell and tissue vulnerability in Alzheimer's disease.
R Freer, P Sormanni, P Ciryam, B Rammner, SO Rizzoli, CM Dobson, M Vendruscolo
Heliyon
(2019)
5
(doi: 10.1016/j.heliyon.2019.e02589)
Label-Free Analysis of Protein Aggregation and Phase Behavior.
Z Toprakcioglu, P Challa, C Xu, TPJ Knowles
ACS nano
(2019)
13
(doi: 10.1021/acsnano.9b05552)
Machine learning for target discovery in drug development
T Rodrigues, GJL Bernardes
Current Opinion in Chemical Biology
(2019)
56
(doi: 10.1016/j.cbpa.2019.10.003)
Protein Microgels from Amyloid Fibril Networks
LWY Roode, U Shimanovich, S Wu, S Perrett, TPJ Knowles
Advances in Experimental Medicine and Biology
(2019)
1174
(doi: 10.1007/978-981-13-9791-2_7)
Dynamics and Control of Peptide Self-Assembly and Aggregation.
G Meisl, TCT Michaels, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Advances in Experimental Medicine and Biology
(2019)
1174
(doi: 10.1007/978-981-13-9791-2_1)
Innenrücktitelbild: Nucleation and Growth of Amino Acid and Peptide Supramolecular Polymers through Liquid–Liquid Phase Separation (Angew. Chem. 50/2019)
C Yuan, A Levin, W Chen, R Xing, Q Zou, TW Herling, PK Challa, TPJ Knowles, X Yan
Angewandte Chemie
(2019)
131
(doi: 10.1002/ange.201913848)
Inside Back Cover: Nucleation and Growth of Amino Acid and Peptide Supramolecular Polymers through Liquid–Liquid Phase Separation (Angew. Chem. Int. Ed. 50/2019)
C Yuan, A Levin, W Chen, R Xing, Q Zou, TW Herling, PK Challa, TPJ Knowles, X Yan
Angewandte Chemie International Edition
(2019)
58
(doi: 10.1002/anie.201913848)
A Sweet Galactose Transfer – Metabolic Oligosaccharide Engineering as a Tool to Study Glycans in Plasmodium Infection
A Kitowski, G Bernardes
(2019)
(doi: 10.26434/chemrxiv.10119302.v1)
Nucleation and Growth of Amino Acid and Peptide Supramolecular Polymers through Liquid–Liquid Phase Separation
C Yuan, A Levin, W Chen, R Xing, Q Zou, TW Herling, PK Challa, TPJ Knowles, X Yan
Angewandte Chemie
(2019)
131
(doi: 10.1002/ange.201911782)
Nucleation and Growth of Amino Acid and Peptide Supramolecular Polymers through Liquid-Liquid Phase Separation.
C Yuan, A Levin, W Chen, R Xing, Q Zou, TW Herling, PK Challa, TPJ Knowles, X Yan
Angew Chem Int Ed Engl
(2019)
58
(doi: 10.1002/anie.201911782)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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