Centre for Misfolding Diseases

Publications

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  • Currently displaying 601 - 620 of 2456 publications
Author(s)
Publication title
Journal Name
Publication year
In vitro measurements of protein–protein interactions show that antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in convalescent serum
S Fiedler, MA Piziorska, V Denninger, AS Morgunov, A Ilsley, AY Malik, MM Schneider, SRA Devenish, G Meisl, A Aguzzi, H Fiegler, TPJ Knowles
(2020)
(doi: 10.1101/2020.12.20.422820)
Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
F Geiger, G Papa, WE Arter, J Acker, KL Saar, N Erkamp, R Qi, J Bravo, S Strauss, G Krainer, OR Burrone, R Jungmann, TPJ Knowles, H Engelke, A Borodavka
(2020)
(doi: 10.1101/2020.12.18.423429)
Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameter.
R Staats, TCT Michaels, P Flagmeier, S Chia, RI Horne, J Habchi, S Linse, TPJ Knowles, CM Dobson, M Vendruscolo
Communications chemistry
(2020)
3
(doi: 10.1038/s42004-020-00412-y)
Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions (vol 16, pg 3586, 2020)
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GJL Bernardes, TPJ Knowles
Soft Matter
(2020)
17
(doi: 10.1039/d0sm90246b)
Physical mechanisms of amyloid nucleation on fluid membranes.
J Krausser, TPJ Knowles, A Šarić
Proc Natl Acad Sci U S A
(2020)
117
(doi: 10.1073/pnas.2007694117)
New solution for fast axial scanning in fluorescence microscopy
W Zong
Light: Science & Applications
(2020)
9
(doi: 10.1038/s41377-020-00442-0)
Widespread occurrence of the droplet state of proteins in the human proteome.
M Hardenberg, A Horvath, V Ambrus, M Fuxreiter, M Vendruscolo
Proceedings of the National Academy of Sciences
(2020)
117
(doi: 10.1073/PNAS.2007670117)
Evolution of Conformation, Nanomechanics, and Infrared Nanospectroscopy of Single Amyloid Fibrils Converting into Microcrystals.
J Adamcik, FS Ruggeri, JT Berryman, A Zhang, TPJ Knowles, R Mezzenga
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
(2020)
8
(doi: 10.1002/advs.202002182)
In Vivo Pretargeting Based on Cysteine-Selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry
VFC Ferreira, BL Oliveira, A D'Onofrio, CM Farinha, L Gano, A Paulo, GJL Bernardes, F Mendes
Bioconjug Chem
(2020)
32
(doi: 10.1021/acs.bioconjchem.0c00551)
Construction of a liquid-liquid phase separation system from the gel-sol transition of elongated protein microgels in a crowding agent
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
(2020)
(doi: 10.1101/2020.12.08.416867)
Sequence determinants of the aggregation of proteins within condensates generated by liquid-liquid phase separation
M Vendruscolo, M Fuxreiter
(2020)
(doi: 10.1101/2020.12.07.414409)
Systematic Activity Maturation of a Single-Domain Antibody with Non-canonical Amino Acids through Chemical Mutagenesis
PR Lindstedt, FA Aprile, P Sormanni, R Rakoto, CM Dobson, GJL Bernardes, M Vendruscolo
Cell Chem Biol
(2020)
28
(doi: 10.1016/j.chembiol.2020.11.002)
Adaptive Optimization of Chemical Reactions with Minimal Experimental Information
G Lopes Bernardes
Cell Reports Physical Science
(2020)
(doi: 10.1016/j.xcrp.2020.100247)
Adaptive Optimization of Chemical Reactions with Minimal Experimental Information
D Reker, EA Hoyt, GJL Bernardes, T Rodrigues
Cell Reports Physical Science
(2020)
1
(doi: 10.1016/j.xcrp.2020.100247)
Biophysical studies of protein misfolding and aggregation in in vivo models of Alzheimer's and Parkinson's diseases (vol 53, 1, 2020)
T Sinnige, K Stroobants, CM Dobson, M Vendruscolo
Quarterly reviews of biophysics
(2020)
53
(doi: 10.1017/S0033583520000104)
Therapeutic strategies to reduce the toxicity of misfolded protein oligomers
RP Kreiser, AK Wright, NR Block, JE Hollows, LT Nguyen, K LeForte, B Mannini, M Vendruscolo, R Limbocker
Int J Mol Sci
(2020)
21
(doi: 10.3390/ijms21228651)
Perphenazine-macrocycle conjugates rapidly sequester the Aβ42 monomer and inhibit amyloid formation
SR Ball, JSP Adamson, MA Sullivan, MR Zimmermann, V Lo, M Sanz-Hernandez, F Jiang, AH Kwan, EL Werry, TPJ Knowles, M Kassiou, G Meisl, MH Todd, PJ Rutledge, M Sunde
(2020)
(doi: 10.1101/2020.11.16.384248)
Machine learning aided top-down proteomics on a microfluidic platform
Y Zhang, MA Wright, KL Saar, P Challa, AS Morgunov, QAE Peter, S Devenish, CM Dobson, TPJ Knowles
(2020)
(doi: 10.1101/2020.11.14.381376)
Structural Characterization of an Unprecedented Lectin-like Antitumoral anti-MUC1 Antibody
J Macías-León, IA Bermejo, A Asín, A García-García, I Compañón, E Jiménez-Moreno, H Coelho, V Mangini, IS Albuquerque, F Marcelo, JL Asensio, GJL Bernardes, HJ Joshi, R Fiammengo, O Blixt, R Hurtado-Guerrero, F Corzana
Chemical Communications
(2020)
56
(doi: 10.1039/d0cc06349e)
On the Mechanism of Self-Assembly by a Hydrogel-Forming Peptide.
GA Braun, BE Ary, AJ Dear, MCH Rohn, AM Payson, DSM Lee, RC Parry, C Friedman, TPJ Knowles, S Linse, KS Åkerfeldt
Biomacromolecules
(2020)
21
(doi: 10.1021/acs.biomac.0c00989)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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