Centre for Misfolding Diseases

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  • Currently displaying 601 - 620 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Microfluidic diffusional sizing for studying protein-protein interactions
MM Schneider, CM Dobson, A Aguzzi, FU Hartl, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2021)
50
Rational design of oligomer-specific antibodies as diagnostic tools for Alzheimer's and Parkinson's diseases
M Vendruscolo
FEBS OPEN BIO
(2021)
11
Environmental Dependence of the Structure of the C-terminal Domain of the SARS-CoV-2 Envelope Protein
K Gadhave, A Kumar, P Kumar, SK Kapuganti, N Garg, M Vendruscolo, R Giri
(2020)
(doi: 10.1101/2020.12.29.424646)
A method of incorporating rate constants as kinetic constraints in molecular dynamics simulations.
ZF Brotzakis, M Vendruscolo, PG Bolhuis
Proceedings of the National Academy of Sciences of the United States of America
(2020)
118
(doi: 10.1073/pnas.2012423118)
Interactions of α-synuclein oligomers with lipid membranes
G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, TPJ Knowles
Biochimica et biophysica acta. Biomembranes
(2020)
1863
(doi: 10.1016/j.bbamem.2020.183536)
Environmental Control of Amyloid Polymorphism by Modulation of Hydrodynamic Stress
J Zhou, L Venturelli, L Keiser, SK Sekatskii, F Gallaire, S Kasas, G Longo, TPJ Knowles, FS Ruggeri, G Dietler
ACS Nano
(2020)
15
(doi: 10.1021/acsnano.0c07570)
In vitro measurements of protein–protein interactions show that antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in convalescent serum
S Fiedler, MA Piziorska, V Denninger, AS Morgunov, A Ilsley, AY Malik, MM Schneider, SRA Devenish, G Meisl, A Aguzzi, H Fiegler, TPJ Knowles
(2020)
(doi: 10.1101/2020.12.20.422820)
Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
F Geiger, G Papa, WE Arter, J Acker, KL Saar, N Erkamp, R Qi, J Bravo, S Strauss, G Krainer, OR Burrone, R Jungmann, TPJ Knowles, H Engelke, A Borodavka
(2020)
(doi: 10.1101/2020.12.18.423429)
Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameter.
R Staats, TCT Michaels, P Flagmeier, S Chia, RI Horne, J Habchi, S Linse, TPJ Knowles, CM Dobson, M Vendruscolo
Communications Chemistry
(2020)
3
(doi: 10.1038/s42004-020-00412-y)
Physical mechanisms of amyloid nucleation on fluid membranes.
J Krausser, TPJ Knowles, A Šarić
Proceedings of the National Academy of Sciences
(2020)
117
(doi: 10.1073/pnas.2007694117)
Widespread occurrence of the droplet state of proteins in the human proteome
M Hardenberg, A Horvath, V Ambrus, M Fuxreiter, M Vendruscolo
Proceedings of the National Academy of Sciences
(2020)
117
(doi: 10.1073/PNAS.2007670117)
New solution for fast axial scanning in fluorescence microscopy.
W Zong
Light, science & applications
(2020)
9
(doi: 10.1038/s41377-020-00442-0)
Evolution of Conformation, Nanomechanics, and Infrared Nanospectroscopy of Single Amyloid Fibrils Converting into Microcrystals
J Adamcik, FS Ruggeri, JT Berryman, A Zhang, TPJ Knowles, R Mezzenga
Adv Sci (Weinh)
(2020)
8
(doi: 10.1002/advs.202002182)
Construction of a liquid-liquid phase separation system from the gel-sol transition of elongated protein microgels in a crowding agent
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
(2020)
(doi: 10.1101/2020.12.08.416867)
In Vivo Pretargeting Based on Cysteine-selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry
VFC Ferreira, BL Oliveira, A D'Onofrio, CM Farinha, L Gano, A Paulo, GJL Bernardes, F Mendes
Bioconjugate Chemistry
(2020)
32
(doi: 10.1021/acs.bioconjchem.0c00551)
Sequence determinants of the aggregation of proteins within condensates generated by liquid-liquid phase separation
M Vendruscolo, M Fuxreiter
(2020)
(doi: 10.1101/2020.12.07.414409)
Systematic Activity Maturation of a Single-Domain Antibody with Non-canonical Amino Acids through Chemical Mutagenesis
PR Lindstedt, FA Aprile, P Sormanni, R Rakoto, CM Dobson, GJL Bernardes, M Vendruscolo
Cell Chem Biol
(2020)
28
(doi: 10.1016/j.chembiol.2020.11.002)
Adaptive Optimization of Chemical Reactions with Minimal Experimental Information
D Reker, EA Hoyt, GJL Bernardes, T Rodrigues
Cell Reports Physical Science
(2020)
1
(doi: 10.1016/j.xcrp.2020.100247)
Biophysical studies of protein misfolding and aggregation in in vivo models of Alzheimer's and Parkinson's diseases - ERRATUM.
T Sinnige, K Stroobants, CM Dobson, M Vendruscolo
Q Rev Biophys
(2020)
53
(doi: 10.1017/S0033583520000104)
Amplification, not spreading limits rate of tau aggregate accumulation in Alzheimer’s disease
G Meisl, Y Zuo, K Allinson, T Rittman, S DeVos, JS Sanchez, CK Xu, KE Duff, KA Johnson, JB Rowe, BT Hyman, TPJ Knowles, D Klenerman
(2020)
(doi: 10.1101/2020.11.16.384727)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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