Centre for Misfolding Diseases

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  • Currently displaying 561 - 580 of 2450 publications
Author(s)
Publication title
Journal Name
Publication year
Dichloro Butenediamides as Irreversible Site‐Selective Protein Conjugation Reagent
V Laserna, D Abegg, CF Afonso, EM Martin, A Adibekian, P Ravn, F Corzana, GJL Bernardes
Angewandte Chemie
(2021)
133
(doi: 10.1002/ange.202108791)
Sequential storage and release of microdroplets
Z Toprakcioglu, TPJ Knowles
Microsystems & nanoengineering
(2021)
7
(doi: 10.1038/s41378-021-00303-9)
Dichloro Butenediamides as Irreversible Site-Selective Protein Conjugation Reagent.
V Laserna, D Abegg, CF Afonso, EM Martin, A Adibekian, P Ravn, F Corzana, GJL Bernardes
Angewandte Chemie International Edition
(2021)
60
(doi: 10.1002/anie.202108791)
Mechanism of secondary nucleation at the single fibril level from direct observations of Aß42 aggregation
MR Zimmermann, SC Bera, G Meisl, S Dasadhikari, S Ghosh, S Linse, K Garai, TPJ Knowles
Journal of the American Chemical Society
(2021)
143
(doi: 10.1021/jacs.1c07228)
Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at physiological pH
ST Dada, MC Hardenberg, LK Mrugalla, MO McKeon, E Klimont, TCT Michaels, M Vendruscolo
(2021)
(doi: 10.1101/2021.09.26.461836)
A maximum caliber approach for continuum path ensembles
PG Bolhuis, ZF Brotzakis, M Vendruscolo
The European Physical Journal B
(2021)
94
(doi: 10.1140/epjb/s10051-021-00154-3)
A conformational switch controlling the toxicity of the prion protein
K Frontzek, M Bardelli, A Senatore, A Henzi, RR Reimann, S Bedir, M Marino, R Hussain, S Jurt, G Meisl, M Pedotti, F Mazzola, G Siligardi, O Zerbe, M Losa, T Knowles, A Lakkaraju, C Zhu, P Schwarz, S Hornemann, MG Holt, L Simonelli, L Varani, A Aguzzi
(2021)
(doi: 10.1101/2021.09.20.460912)
Sequential Storage and Release of Microdroplets for On and Off-chip Analysis
Z Toprakcioglu, T Knowles
(2021)
(doi: 10.33774/chemrxiv-2021-66zrn)
Sequential Storage and Release of Microdroplets for On and Off-chip Analysis
Z Toprakcioglu, T Knowles
(2021)
(doi: 10.26434/chemrxiv-2021-66zrn)
Liquid-liquid phase separation underpins the formation of replication factories in rotaviruses
F Geiger, J Acker, G Papa, X Wang, WE Arter, KL Saar, N Erkamp, R Qi, J Bravo, S Strauss, G Krainer, OR Burrone, R Jungmann, TPJ Knowles, H Engelke, A Borodavka
The EMBO Journal
(2021)
40
(doi: 10.15252/embj.2021107711)
The binding of the small heat-shock protein αB-crystallin to fibrils of α-synuclein is driven by entropic forces.
T Scheidt, JA Carozza, CC Kolbe, FA Aprile, O Tkachenko, MMJ Bellaiche, G Meisl, QAE Peter, TW Herling, S Ness, M Castellana-Cruz, JLP Benesch, M Vendruscolo, CM Dobson, P Arosio, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2021)
118
(doi: 10.1073/pnas.2108790118)
Combating small-molecule aggregation with machine learning
K Lee, A Yang, Y-C Lin, D Reker, GJL Bernardes, T Rodrigues
Cell Reports Physical Science
(2021)
2
(doi: 10.1016/j.xcrp.2021.100573)
Deformable and Robust Core–Shell Protein Microcapsules Templated by Liquid–Liquid Phase‐Separated Microdroplets
Y Xu, Y Shen, TCT Michaels, KN Baumann, D Vigolo, Q Peter, Y Lu, KL Saar, D Vella, H Zhu, B Li, H Yang, APM Guttenplan, M Rodriguez‐Garcia, D Klenerman, TPJ Knowles
Advanced Materials Interfaces
(2021)
8
(doi: 10.1002/admi.202101071)
New Frontiers for Machine Learning in Protein Science.
AS Morgunov, KL Saar, M Vendruscolo, TPJ Knowles
J Mol Biol
(2021)
433
(doi: 10.1016/j.jmb.2021.167232)
Assessment of Therapeutic Antibody Developability by Combinations of In Vitro and In Silico Methods.
A-M Wolf Pérez, N Lorenzen, M Vendruscolo, P Sormanni
Methods Mol Biol
(2021)
2313
(doi: 10.1007/978-1-0716-1450-1_4)
The Amyloid-β Pathway in Alzheimer’s Disease
H Hampel, J Hardy, K Blennow, C Chen, G Perry, SH Kim, VL Villemagne, P Aisen, M Vendruscolo, T Iwatsubo, CL Masters, M Cho, L Lannfelt, JL Cummings, A Vergallo
Mol Psychiatry
(2021)
26
(doi: 10.1038/s41380-021-01249-0)
Unraveling the Physicochemical Determinants of Protein Liquid-liquid Phase Separation by Nanoscale Infrared Vibrational Spectroscopy.
FS Ruggeri, AM Miller, M Vendruscolo, TPJ Knowles
Bio-protocol
(2021)
11
(doi: 10.21769/bioprotoc.4122)
Liquid–Liquid Phase‐Separated Systems from Reversible Gel–Sol Transition of Protein Microgels (Adv. Mater. 33/2021)
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
Advanced Materials
(2021)
33
(doi: 10.1002/adma.202170258)
Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and Trodusquemine
S Errico, H Ramshini, C Capitini, C Canale, M Spaziano, D Barbut, M Calamai, M Zasloff, R Oropesa-Nuñez, M Vendruscolo, F Chiti
ACS chemical neuroscience
(2021)
12
(doi: 10.1021/acschemneuro.1c00327)
Sequence Determinants of the Aggregation of Proteins Within Condensates Generated by Liquid-liquid Phase Separation: Sequence code of aggregation in protein condensates
M Vendruscolo, M Fuxreiter
Journal of molecular biology
(2021)
434
(doi: 10.1016/j.jmb.2021.167201)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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