Centre for Misfolding Diseases

Publications

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  • Currently displaying 541 - 560 of 2396 publications
Author(s)
Publication title
Journal Name
Publication year
Liquid–Liquid Phase‐Separated Systems from Reversible Gel–Sol Transition of Protein Microgels
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
Advanced Materials
(2021)
33
(doi: 10.1002/adma.202008670)
Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response
P Joshi, M Perni, R Limbocker, B Mannini, S Casford, S Chia, J Habchi, J Labbadia, CM Dobson, M Vendruscolo
Communications Biology
(2021)
4
(doi: 10.1038/s42003-021-02218-7)
Protein Conjugation by Electrophilic Alkynylation using 5-(Alkynyl) dibenzothiophenium Triflates
V Laserna, A Istrate, K Kafuta, TA Hakala, TPJ Knowles, M Alcarazo, GJL Bernardes
Bioconjugate Chemistry
(2021)
32
(doi: 10.1021/acs.bioconjchem.1c00317)
Biomembranes in Bioelectronic Sensing
AK Jayaram, AM Pappa, S Ghosh, ZA Manzer, WC Traberg, TPJ Knowles, S Daniel, RM Owens
Trends in Biotechnology
(2021)
40
(doi: 10.1016/j.tibtech.2021.06.001)
Soluble inflammatory Aβ-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease
DI Sideris, JSH Danial, D Emin, FS Ruggeri, Z Xia, YP Zhang, E Lobanova, H Dakin, S De, A Miller, JC Sang, TPJ Knowles, M Vendruscolo, G Fraser, D Crowther, D Klenerman
Brain Communications
(2021)
3
(doi: 10.1093/braincomms/fcab147)
Distinct responses of human peripheral blood cells to different misfolded protein oligomers.
M Leal-Lasarte, B Mannini, F Chiti, M Vendruscolo, CM Dobson, C Roodveldt, D Pozo
Immunology
(2021)
164
(doi: 10.1111/imm.13377)
Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers
R Limbocker, R Staats, S Chia, FS Ruggeri, B Mannini, CK Xu, M Perni, R Cascella, A Bigi, LR Sasser, NR Block, AK Wright, RP Kreiser, ET Custy, G Meisl, S Errico, J Habchi, P Flagmeier, T Kartanas, JE Hollows, LT Nguyen, K LeForte, D Barbut, JR Kumita, C Cecchi, M Zasloff, TPJ Knowles, CM Dobson, F Chiti, M Vendruscolo
Front Neurosci
(2021)
15
(doi: 10.3389/fnins.2021.680026)
Controlled self-assembly of plant proteins into high-performance multifunctional nanostructured films.
A Kamada, M Rodriguez-Garcia, FS Ruggeri, Y Shen, A Levin, TPJ Knowles
Nature communications
(2021)
12
(doi: 10.1038/s41467-021-23813-6)
Machine learning-aided protein identification from multidimensional signatures
Y Zhang, MA Wright, KL Saar, P Challa, AS Morgunov, QAE Peter, S Devenish, CM Dobson, TPJ Knowles
Lab on A Chip
(2021)
21
(doi: 10.1039/d0lc01148g)
Generic nature of the condensed states of proteins
M Fuxreiter, M Vendruscolo
Nature cell biology
(2021)
23
(doi: 10.1038/s41556-021-00697-8)
Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy
ZF Brotzakis, T Löhr, M Vendruscolo
Chem Sci
(2021)
12
(doi: 10.1039/d1sc00244a)
pH-Responsive Capsules with a Fibril Scaffold Shell Assembled from an Amyloidogenic Peptide.
U Shimanovich, A Levin, D Eliaz, T Michaels, Z Toprakcioglu, B Frohm, E De Genst, S Linse, KS Åkerfeldt, TPJ Knowles
Small (Weinheim an der Bergstrasse, Germany)
(2021)
17
(doi: 10.1002/smll.202007188)
Pulsed Hydrogen-Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer's Disease Mutants.
E Illes-Toth, G Meisl, DL Rempel, TPJ Knowles, ML Gross
ACS Chemical Neuroscience
(2021)
12
(doi: 10.1021/acschemneuro.1c00072)
In situ Sub-Cellular Identification of Functional Amyloids in Bacteria and Archaea by Infrared Nanospectroscopy
DE Otzen, MS Dueholm, Z Najarzadeh, TPJ Knowles, FS Ruggeri
Small methods
(2021)
5
(doi: 10.1002/smtd.202001002)
Rapid highly-sensitive general protein quantification through on-chip chemiluminescence
HK Chiu, T Kartanas, KL Saar, CM Luxhøj, S Devenish, TPJ Knowles
Biomicrofluidics
(2021)
15
(doi: 10.1063/5.0039872)
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
M Emmenegger, E De Cecco, M Hruska-Plochan, T Eninger, MM Schneider, M Barth, E Tantardini, P de Rossi, M Bacioglu, RG Langston, A Kaganovich, N Bengoa-Vergniory, A Gonzalez-Guerra, M Avar, D Heinzer, R Reimann, LM Häsler, TW Herling, NS Matharu, N Landeck, K Luk, R Melki, PJ Kahle, S Hornemann, TPJ Knowles, MR Cookson, M Polymenidou, M Jucker, A Aguzzi
(2021)
(doi: 10.1101/2021.04.25.441302)
Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum
S Fiedler, MA Piziorska, V Denninger, AS Morgunov, A Ilsley, AY Malik, MM Schneider, SRA Devenish, G Meisl, V Kosmoliaptsis, A Aguzzi, H Fiegler, TPJ Knowles
ACS Infect Dis
(2021)
7
(doi: 10.1021/acsinfecdis.1c00047)
Critical assessment of protein intrinsic disorder prediction.
M Necci, D Piovesan, CAID Predictors, DisProt Curators, SCE Tosatto
Nat Methods
(2021)
18
(doi: 10.1038/s41592-021-01117-3)
Elongation rate and average length of amyloid fibrils in solution using isotope-labelled small-angle neutron scattering
BJ Eves, JJ Doutch, AE Terry, H Yin, M Moulin, M Haertlein, VT Forsyth, P Flagmeier, TPJ Knowles, DM Dias, G Lotze, AM Seddon, AM Squires
RSC chemical biology
(2021)
2
(doi: 10.1039/d1cb00001b)
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression
J Conde, RA Pumroy, C Baker, T Rodrigues, A Guerreiro, BB Sousa, MC Marques, BP de Almeida, S Lee, EP Leites, D Picard, A Samanta, SH Vaz, F Sieglitz, M Langini, M Remke, R Roque, T Weiss, M Weller, Y Liu, S Han, F Corzana, VA Morais, CC Faria, T Carvalho, P Filippakopoulos, B Snijder, NL Barbosa-Morais, VY Moiseenkova-Bell, GJL Bernardes
ACS Cent Sci
(2021)
7
(doi: 10.1021/acscentsci.1c00070)
Yusuf Hamied Department of Chemistry
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