Centre for Misfolding Diseases

Publications

Tips on using this search form

  • All search terms are case-insensitive
  • If you specify more than one search option (e.g. you search for both "Authors" and "Paper title") then the publications returned will be those that match all of your search terms
  • To reset the search form, click here
  • Currently displaying 541 - 560 of 2399 publications
Author(s)
Publication title
Journal Name
Publication year
Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
U Nowicka, P Chroscicki, K Stroobants, M Sladowska, M Turek, B Uszczynska-Ratajczak, R Kundra, T Goral, M Perni, CM Dobson, M Vendruscolo, A Chacinska
eLife
(2021)
10
(doi: 10.7554/eLife.65484)
Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5‑LOX Inhibitor that Limits Inflammation
K Neukirch, K Alsabil, C-P Dinh, R Bilancia, M Raasch, A Ville, I Cerqua, G Viault, D Bréard, S Pace, V Temml, E Brunner, PM Jordan, MC Marques, K Loeser, A Gollowitzer, S Permann, J Gerstmeier, S Lorkowski, H Stuppner, U Garscha, T Rodrigues, GJL Bernardes, D Schuster, D Séraphin, P Richomme, A Rossi, AS Mosig, F Roviezzo, O Werz, J-J Helesbeux, A Koeberle
Journal of medicinal chemistry
(2021)
64
(doi: 10.1021/acs.jmedchem.1c00806)
Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions
Z Zawada, Z Guo, BL Oliveira, CD Navo, H Li, PMSD Cal, F Corzana, G Jiménez-Osés, GJL Bernardes
Bioconjug Chem
(2021)
32
(doi: 10.1021/acs.bioconjchem.1c00276)
Modulation of the Interactions Between α-Synuclein and Lipid Membranes by Post-translational Modifications.
R Bell, M Vendruscolo
Frontiers in Neurology
(2021)
12
(doi: 10.3389/fneur.2021.661117)
Exogenous misfolded protein oligomers can cross the intestinal barrier and cause a disease phenotype in C. elegans
M Perni, B Mannini, CK Xu, JR Kumita, CM Dobson, F Chiti, M Vendruscolo
Sci Rep
(2021)
11
(doi: 10.1038/s41598-021-93527-8)
Liquid-liquid phase separated systems from reversible gel-sol transition of protein microgels
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
Advanced Materials
(2021)
33
(doi: 10.1002/adma.202008670)
The unhappy chaperone.
S Linse, K Thalberg, TPJ Knowles
QRB Discov
(2021)
2
(doi: 10.1017/qrd.2021.5)
Two human metabolites rescue a C. elegans model of Alzheimer's disease via a cytosolic unfolded protein response
P Joshi, M Perni, R Limbocker, B Mannini, S Casford, S Chia, J Habchi, J Labbadia, CM Dobson, M Vendruscolo
Communications Biology
(2021)
4
(doi: 10.1038/s42003-021-02218-7)
Protein Conjugation by Electrophilic Alkynylation Using 5‑(Alkynyl)dibenzothiophenium Triflates
V Laserna, A Istrate, K Kafuta, TA Hakala, TPJ Knowles, M Alcarazo, GJL Bernardes
Bioconjugate chemistry
(2021)
32
(doi: 10.1021/acs.bioconjchem.1c00317)
Biomembranes in Bioelectronic Sensing
AK Jayaram, AM Pappa, S Ghosh, ZA Manzer, WC Traberg, TPJ Knowles, S Daniel, RM Owens
Trends in Biotechnology
(2021)
40
(doi: 10.1016/j.tibtech.2021.06.001)
Soluble inflammatory Aβ-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease
DI Sideris, JSH Danial, D Emin, FS Ruggeri, Z Xia, YP Zhang, E Lobanova, H Dakin, S De, A Miller, JC Sang, TPJ Knowles, M Vendruscolo, G Fraser, D Crowther, D Klenerman
Brain Communications
(2021)
3
(doi: 10.1093/braincomms/fcab147)
Distinct responses of human peripheral blood cells to different misfolded protein oligomers
M Leal-Lasarte, B Mannini, F Chiti, M Vendruscolo, CM Dobson, C Roodveldt, D Pozo
Immunology
(2021)
164
(doi: 10.1111/imm.13377)
Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers
R Limbocker, R Staats, S Chia, FS Ruggeri, B Mannini, CK Xu, M Perni, R Cascella, A Bigi, LR Sasser, NR Block, AK Wright, RP Kreiser, ET Custy, G Meisl, S Errico, J Habchi, P Flagmeier, T Kartanas, JE Hollows, LT Nguyen, K LeForte, D Barbut, JR Kumita, C Cecchi, M Zasloff, TPJ Knowles, CM Dobson, F Chiti, M Vendruscolo
Front Neurosci
(2021)
15
(doi: 10.3389/fnins.2021.680026)
Controlled self-assembly of plant proteins into high-performance multifunctional nanostructured films
A Kamada, M Rodriguez-Garcia, FS Ruggeri, Y Shen, A Levin, TPJ Knowles
Nature Communications
(2021)
12
(doi: 10.1038/s41467-021-23813-6)
Machine learning-aided protein identification from multidimensional signatures.
Y Zhang, MA Wright, KL Saar, P Challa, AS Morgunov, QAE Peter, S Devenish, CM Dobson, TPJ Knowles
Lab Chip
(2021)
21
(doi: 10.1039/d0lc01148g)
Generic nature of the condensed states of proteins.
M Fuxreiter, M Vendruscolo
Nature Cell Biology
(2021)
23
(doi: 10.1038/s41556-021-00697-8)
Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy.
ZF Brotzakis, T Löhr, M Vendruscolo
Chem Sci
(2021)
12
(doi: 10.1039/d1sc00244a)
pH-Responsive Capsules with a Fibril Scaffold Shell Assembled from an Amyloidogenic Peptide.
U Shimanovich, A Levin, D Eliaz, T Michaels, Z Toprakcioglu, B Frohm, E De Genst, S Linse, KS Åkerfeldt, TPJ Knowles
Small
(2021)
17
(doi: 10.1002/smll.202007188)
Pulsed Hydrogen–Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer’s Disease Mutants
E Illes-Toth, G Meisl, DL Rempel, TPJ Knowles, ML Gross
ACS chemical neuroscience
(2021)
12
(doi: 10.1021/acschemneuro.1c00072)
In situ Sub-Cellular Identification of Functional Amyloids in Bacteria and Archaea by Infrared Nanospectroscopy
DE Otzen, MS Dueholm, Z Najarzadeh, TPJ Knowles, FS Ruggeri
Small methods
(2021)
5
(doi: 10.1002/smtd.202001002)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
Contacts
Directions

Privacy and cookie policy

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge